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Showing 1 to 12 of 662 entries
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Past, present, and future of hormonal therapy in recurrent endometrial cancer.

International journal of women's health

Carlson MJ, Thiel KW, Leslie KK.
PMID: 24833920
Int J Womens Health. 2014 May 02;6:429-35. doi: 10.2147/IJWH.S40942. eCollection 2014.

Endometrial cancer is a heterogeneous disease. Type I cancers are hormonally driven, typically present with a low grade at an early stage, and are of endometrioid histology. These cancers are often cured by surgery, and the rate of recurrence...

Hormonal based treatment of ovarian anaplastic ependymoma with anastrozole.

Gynecologic oncology reports

Gorski JW, Taylor JS, Zhang J, Liu J, Jazaeri AA.
PMID: 28393092
Gynecol Oncol Rep. 2017 Mar 14;20:93-96. doi: 10.1016/j.gore.2017.03.005. eCollection 2017 May.

OBJECTIVE: Ovarian anaplastic ependymoma is a rare gynecologic malignancy that poses diagnostic and treatment challenges. Treatment of sub-optimally debulked disease usually portends poor prognosis. Molecular testing of tumor specimen can identify more specific targets for additional therapy such as...

Endometriosis: alternative methods of medical treatment.

International journal of women's health

Muñoz-Hernando L, Muñoz-Gonzalez JL, Marqueta-Marques L, Alvarez-Conejo C, Tejerizo-García Á, Lopez-Gonzalez G, Villegas-Muñoz E, Martin-Jimenez A, Jiménez-López JS.
PMID: 26089705
Int J Womens Health. 2015 Jun 11;7:595-603. doi: 10.2147/IJWH.S78829. eCollection 2015.

Endometriosis is an inflammatory estrogen-dependent disease defined by the presence of endometrial glands and stroma at extrauterine sites. The main purpose of endometriosis management is alleviating pain associated to the disease. This can be achieved surgically or medically, although...

Influence of aromatase inhibitors therapy on the occurrence of rheumatoid arthritis in women with breast cancer: results from a large population-based study of the Italian Society for Rheumatology.

RMD open

Caprioli M, Carrara G, Sakellariou G, Silvagni E, Scirè CA.
PMID: 29071118
RMD Open. 2017 Sep 28;3(2):e000523. doi: 10.1136/rmdopen-2017-000523. eCollection 2017.

OBJECTIVES: The purpose of this study was to evaluate the risk of developing rheumatoid arthritis (RA) in a population of patients with breast cancer treated with aromatase inhibitors (AIs) compared with tamoxifen.METHODS: Data were collected from the administrative healthcare...

ER-positive breast cancer patients with more than three positive nodes or grade 3 tumors are at high risk of late recurrence after 5-year adjuvant endocrine therapy.

OncoTargets and therapy

Song F, Zhang J, Li S, Wu J, Jin T, Qin J, Wang Y, Wang M, Xu J.
PMID: 29042797
Onco Targets Ther. 2017 Oct 03;10:4859-4867. doi: 10.2147/OTT.S142698. eCollection 2017.

PURPOSE: Currently, although several clinical trials available give strong suggestions that extension of endocrine therapy has benefits, the risk level at which patients may benefit from extended endocrine therapy remains uncertain. This study aimed to identify the proportion of...

Targeted therapy for breast cancer prevention.

Frontiers in oncology

den Hollander P, Savage MI, Brown PH.
PMID: 24069582
Front Oncol. 2013 Sep 23;3:250. doi: 10.3389/fonc.2013.00250.

With a better understanding of the etiology of breast cancer, molecularly targeted drugs have been developed and are being testing for the treatment and prevention of breast cancer. Targeted drugs that inhibit the estrogen receptor (ER) or estrogen-activated pathways...

Aromatase inhibitors-induced bone loss in early breast cancer.

BoneKEy reports

Body JJ.
PMID: 24936287
Bonekey Rep. 2012 Oct 03;1:201. doi: 10.1038/bonekey.2012.201. eCollection 2012.

Women with breast cancer have an increased prevalence and incidence of fractures. This increased risk of fracture has become most evident following the use of aromatase inhibitors (AIs) as standard adjuvant therapy. AI-induced bone loss occurs at more than...

Survival benefit of zoledronic Acid in postmenopausal breast cancer patients receiving aromatase inhibitors.

Journal of breast cancer

Ahn SG, Kim SH, Lee HM, Lee SA, Jeong J.
PMID: 25548583
J Breast Cancer. 2014 Dec;17(4):350-5. doi: 10.4048/jbc.2014.17.4.350. Epub 2014 Dec 26.

PURPOSE: A growing body of evidence indicates that zoledronic acid (ZA) can improve the clinical outcome in patients with breast cancer and low estrogen levels. In the present study, we aimed to investigate the survival benefit of ZA administration...

Primary Hormone Therapy in Elderly Women with Hormone-Sensitive Locoregional Breast Cancer: Endocrine Therapy Alone Is a Reasonable Alternative in Selected Patients.

Breast care (Basel, Switzerland)

Quiroga-García V, Cirauqui-Cirauqui B, Bugés-Sánchez C, Luna-Tomás MÁ, Castellà-Fernández EM, Mariscal-Martínez A, Margelí-Vila M.
PMID: 26648829
Breast Care (Basel). 2015 Jul;10(3):179-83. doi: 10.1159/000382112. Epub 2015 May 22.

BACKGROUND: Treatment with aromatase inhibitors (AIs) followed by surgery is often recommended for women with locoregional hormone-sensitive breast cancer. However, no study has compared the efficacy of AIs alone versus AIs followed by surgery.METHODS: 33 postmenopausal breast cancer patients...

Economic Evaluetion of Fulvestrant 500 MG (F500) Versus Original Nonsteroidal Aromatase Inhibitors in Patient with Advanced Breast Canser in Russia (2 LINE THERAPY).

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Krysanov I, Tyapkina M.
PMID: 27202276
Value Health. 2014 Nov;17(7):A637. doi: 10.1016/j.jval.2014.08.2291. Epub 2014 Oct 26.

No abstract available.

Variations in the body mass index in Brazilian women undergoing adjuvant chemotherapy for breast cancer.

Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia

Ricci MD, Formigoni MC, Zuliani LM, Aoki DS, Mota BS, Filassi JR, Piato JR, Baracat EC.
PMID: 25493402
Rev Bras Ginecol Obstet. 2014 Nov;36(11):503-508. doi: 10.1590/s0100-720320140005081. Epub 2014 Nov 01.

PURPOSE: To evaluate variations in the body mass index in patients undergoing adjuvant chemotherapy for breast cancer, and to associate these changes with patient's age and adjuvant chemotherapy regimen.METHODS: We performed a retrospective cohort study in order to correlate...

Treatment of hormone positive uterine leiomyosarcoma with aromatase inhibitors.

Clinical sarcoma research

Thanopoulou E, Thway K, Khabra K, Judson I.
PMID: 25018868
Clin Sarcoma Res. 2014 Jun 26;4:5. doi: 10.1186/2045-3329-4-5. eCollection 2014.

BACKGROUND: Aromatase inhibitors (AIs) have not been used consistently as part of the management of hormone receptor positive uterine leiomyosarcomas (ULMS). As a result, the published data regarding the efficacy of AIs in this subtype of ULMS are sparse.METHODS:...

Showing 1 to 12 of 662 entries