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Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some …

evaluation

Sondhi SM, Lozach O.
GSID: TXu01aBjYGoJ
SM Sondhi, N Singh, A Kumar, O Lozach… - Bioorganic & medicinal …, 2006 - Elsevier

A series of N-(acridin-9-yl)-4-(benzo[d]imidazol/oxazol-2-yl) benzamides has been synthesized by the condensation of 9-aminoacridine derivatives with benzimidazole or benzoxazole derivatives. Condensation of 2-hydroxy naphthaldehyde with functionalized diamines leads …

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Sondhi, S. M., Singh, N., Kumar, A., Lozach, O., & Meijer, L. (2006). Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases. Bioorganic & medicinal chemistry, 14(11), 3758-3765.
Sondhi, Sham M., et al. "Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases." Bioorganic & medicinal chemistry 14.11 (2006): 3758-3765.
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Strain-promoted oxidative annulation of arynes and cyclooctynes with benzamides: palladium-catalyzed C-H/N-H activation for the synthesis of N-heterocycles.

Organic letters

Peng X, Wang W, Jiang C, Sun D, Xu Z, Tung CH.
PMID: 25275617
Org Lett. 2014 Oct 17;16(20):5354-7. doi: 10.1021/ol5025426. Epub 2014 Oct 02.

Strained alkynes include arynes and cyclooctynes reacted with N-methoxyamides through palladium-catalyzed C-H/N-H activation for the first time. A variety of important N-heterocycles such as phenanthridinones and isoquinolones were constructed in one step with high efficiency.

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Peng X, Wang W, Jiang C, et al. Strain-promoted oxidative annulation of arynes and cyclooctynes with benzamides: palladium-catalyzed C-H/N-H activation for the synthesis of N-heterocycles. Org Lett. 2014;16(20):5354-7doi: 10.1021/ol5025426.
Peng, X., Wang, W., Jiang, C., Sun, D., Xu, Z., & Tung, C. H. (2014). Strain-promoted oxidative annulation of arynes and cyclooctynes with benzamides: palladium-catalyzed C-H/N-H activation for the synthesis of N-heterocycles. Organic letters, 16(20), 5354-7. https://doi.org/10.1021/ol5025426
Peng, Xianglong, et al. "Strain-promoted oxidative annulation of arynes and cyclooctynes with benzamides: palladium-catalyzed C-H/N-H activation for the synthesis of N-heterocycles." Organic letters vol. 16,20 (2014): 5354-7. doi: https://doi.org/10.1021/ol5025426
Peng X, Wang W, Jiang C, Sun D, Xu Z, Tung CH. Strain-promoted oxidative annulation of arynes and cyclooctynes with benzamides: palladium-catalyzed C-H/N-H activation for the synthesis of N-heterocycles. Org Lett. 2014 Oct 17;16(20):5354-7. doi: 10.1021/ol5025426. Epub 2014 Oct 02. PMID: 25275617.
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Copper-Catalyzed Intramolecular Benzylic C-H Amination for the Synthesis of Isoindolinones.

The Journal of organic chemistry

Yamamoto C, Takamatsu K, Hirano K, Miura M.
PMID: 27504671
J Org Chem. 2016 Sep 02;81(17):7675-84. doi: 10.1021/acs.joc.6b01393. Epub 2016 Aug 18.

A copper-catalyzed intramolecular amination occurs at the benzylic C-H of 2-methylbenzamides to deliver the corresponding isoindolinones of great interest in medicinal chemistry. The mild and abundant MnO2 works well as a terminal oxidant, and the reaction proceeds smoothly under...

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Yamamoto C, Takamatsu K, Hirano K, et al. Copper-Catalyzed Intramolecular Benzylic C-H Amination for the Synthesis of Isoindolinones. J Org Chem. 2016;81(17):7675-84doi: 10.1021/acs.joc.6b01393.
Yamamoto, C., Takamatsu, K., Hirano, K., & Miura, M. (2016). Copper-Catalyzed Intramolecular Benzylic C-H Amination for the Synthesis of Isoindolinones. The Journal of organic chemistry, 81(17), 7675-84. https://doi.org/10.1021/acs.joc.6b01393
Yamamoto, Chiaki, et al. "Copper-Catalyzed Intramolecular Benzylic C-H Amination for the Synthesis of Isoindolinones." The Journal of organic chemistry vol. 81,17 (2016): 7675-84. doi: https://doi.org/10.1021/acs.joc.6b01393
Yamamoto C, Takamatsu K, Hirano K, Miura M. Copper-Catalyzed Intramolecular Benzylic C-H Amination for the Synthesis of Isoindolinones. J Org Chem. 2016 Sep 02;81(17):7675-84. doi: 10.1021/acs.joc.6b01393. Epub 2016 Aug 18. PMID: 27504671.
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Corrigendum to "Efficacy of a high free iodine barrier teat disinfectant for the prevention of naturally occurring new intramammary infections and clinical mastitis in dairy cows" (J. Dairy Sci. 100:3930-3939).

Journal of dairy science

Martins CMMR, Pinheiro ESC, Gentilini M, Benavides ML, Santos MV.
PMID: 28923657
J Dairy Sci. 2017 Oct;100(10):8630. doi: 10.3168/jds.2017-100-10-8630.

No abstract available.

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Martins CMMR, Pinheiro ESC, Gentilini M, et al. Corrigendum to "Efficacy of a high free iodine barrier teat disinfectant for the prevention of naturally occurring new intramammary infections and clinical mastitis in dairy cows" (J. Dairy Sci. 100:3930-3939). J Dairy Sci. 2017;100(10):8630doi: 10.3168/jds.2017-100-10-8630.
Martins, C. M. M. R., Pinheiro, E. S. C., Gentilini, M., Benavides, M. L., & Santos, M. V. (2017). Corrigendum to "Efficacy of a high free iodine barrier teat disinfectant for the prevention of naturally occurring new intramammary infections and clinical mastitis in dairy cows" (J. Dairy Sci. 100:3930-3939). Journal of dairy science, 100(10), 8630. https://doi.org/10.3168/jds.2017-100-10-8630
Martins, C M M R, et al. "Corrigendum to "Efficacy of a high free iodine barrier teat disinfectant for the prevention of naturally occurring new intramammary infections and clinical mastitis in dairy cows" (J. Dairy Sci. 100:3930-3939)." Journal of dairy science vol. 100,10 (2017): 8630. doi: https://doi.org/10.3168/jds.2017-100-10-8630
Martins CMMR, Pinheiro ESC, Gentilini M, Benavides ML, Santos MV. Corrigendum to "Efficacy of a high free iodine barrier teat disinfectant for the prevention of naturally occurring new intramammary infections and clinical mastitis in dairy cows" (J. Dairy Sci. 100:3930-3939). J Dairy Sci. 2017 Oct;100(10):8630. doi: 10.3168/jds.2017-100-10-8630. PMID: 28923657.
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Chasing after Non-cyanobacterial Nitrogen Fixation in Marine Pelagic Environments.

Frontiers in microbiology

Moisander PH, Benavides M, Bonnet S, Berman-Frank I, White AE, Riemann L.
PMID: 28943875
Front Microbiol. 2017 Sep 08;8:1736. doi: 10.3389/fmicb.2017.01736. eCollection 2017.

Traditionally, cyanobacterial activity in oceanic photic layers was considered responsible for the marine pelagic dinitrogen (N

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Moisander PH, Benavides M, Bonnet S, et al. Chasing after Non-cyanobacterial Nitrogen Fixation in Marine Pelagic Environments. Front Microbiol. 2017;8:1736doi: 10.3389/fmicb.2017.01736.
Moisander, P. H., Benavides, M., Bonnet, S., Berman-Frank, I., White, A. E., & Riemann, L. (2017). Chasing after Non-cyanobacterial Nitrogen Fixation in Marine Pelagic Environments. Frontiers in microbiology, 81736. https://doi.org/10.3389/fmicb.2017.01736
Moisander, Pia H, et al. "Chasing after Non-cyanobacterial Nitrogen Fixation in Marine Pelagic Environments." Frontiers in microbiology vol. 8 (2017): 1736. doi: https://doi.org/10.3389/fmicb.2017.01736
Moisander PH, Benavides M, Bonnet S, Berman-Frank I, White AE, Riemann L. Chasing after Non-cyanobacterial Nitrogen Fixation in Marine Pelagic Environments. Front Microbiol. 2017 Sep 08;8:1736. doi: 10.3389/fmicb.2017.01736. eCollection 2017. PMID: 28943875; PMCID: PMC5596534.
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Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route.

The Journal of chemical physics

Benavides AL, Aragones JL, Vega C.
PMID: 27036458
J Chem Phys. 2016 Mar 28;144(12):124504. doi: 10.1063/1.4943780.

The solubility of NaCl in water is evaluated by using three force field models: Joung-Cheatham for NaCl dissolved in two different water models (SPC/E and TIP4P/2005) and Smith Dang NaCl model in SPC/E water. The methodology based on free-energy...

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Benavides AL, Aragones JL, Vega C. Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route. J Chem Phys. 2016;144(12):124504doi: 10.1063/1.4943780.
Benavides, A. L., Aragones, J. L., & Vega, C. (2016). Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route. The Journal of chemical physics, 144(12), 124504. https://doi.org/10.1063/1.4943780
Benavides, A L, et al. "Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route." The Journal of chemical physics vol. 144,12 (2016): 124504. doi: https://doi.org/10.1063/1.4943780
Benavides AL, Aragones JL, Vega C. Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route. J Chem Phys. 2016 Mar 28;144(12):124504. doi: 10.1063/1.4943780. PMID: 27036458.
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Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C-H Cleavage.

Organic letters

Miura W, Hirano K, Miura M.
PMID: 26226391
Org Lett. 2015 Aug 21;17(16):4034-7. doi: 10.1021/acs.orglett.5b01940. Epub 2015 Jul 30.

A Cu(OAc)2/Cy2NMe-mediated oxidative direct coupling of benzamides with maleimides has been developed. The aromatic C-H alkenylation with the aid of an 8-aminoquinoline-based bidentate directing group is followed by an intramolecular aza-Michael-type addition to form the isoindolone-incorporated spirosuccinimides, which are...

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Miura W, Hirano K, Miura M. Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C-H Cleavage. Org Lett. 2015;17(16):4034-7doi: 10.1021/acs.orglett.5b01940.
Miura, W., Hirano, K., & Miura, M. (2015). Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C-H Cleavage. Organic letters, 17(16), 4034-7. https://doi.org/10.1021/acs.orglett.5b01940
Miura, Wataru, et al. "Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C-H Cleavage." Organic letters vol. 17,16 (2015): 4034-7. doi: https://doi.org/10.1021/acs.orglett.5b01940
Miura W, Hirano K, Miura M. Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C-H Cleavage. Org Lett. 2015 Aug 21;17(16):4034-7. doi: 10.1021/acs.orglett.5b01940. Epub 2015 Jul 30. PMID: 26226391.
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Effect of Fodder Tree Species with Condensed Tannin Contents on In vitro Methane Production.

Asian-Australasian journal of animal sciences

Vázquez EG, Medina LH, Benavides LM, Caratachea AJ, Razo GS, Burgos AJ, Rodríguez RO.
PMID: 26732330
Asian-Australas J Anim Sci. 2016 Jan;29(1):73-9. doi: 10.5713/ajas.15.0464.

The objective was to evaluate the effect of fodder tree species (FTS) with condensed tannin contents: Cordia elaeagnoides, Platymiscium lasiocarpum, Vitex mollis, and Haematoxylon brasiletto, on in vitro methane (CH4) production at 24 h post incubation. The analysis was...

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Vázquez EG, Medina LH, Benavides LM, et al. Effect of Fodder Tree Species with Condensed Tannin Contents on In vitro Methane Production. Asian-Australas J Anim Sci. 2016;29(1):73-9doi: 10.5713/ajas.15.0464.
Vázquez, E. G., Medina, L. H., Benavides, L. M., Caratachea, A. J., Razo, G. S., Burgos, A. J., & Rodríguez, R. O. (2016). Effect of Fodder Tree Species with Condensed Tannin Contents on In vitro Methane Production. Asian-Australasian journal of animal sciences, 29(1), 73-9. https://doi.org/10.5713/ajas.15.0464
Vázquez, Ernestina Gutiérrez, et al. "Effect of Fodder Tree Species with Condensed Tannin Contents on In vitro Methane Production." Asian-Australasian journal of animal sciences vol. 29,1 (2016): 73-9. doi: https://doi.org/10.5713/ajas.15.0464
Vázquez EG, Medina LH, Benavides LM, Caratachea AJ, Razo GS, Burgos AJ, Rodríguez RO. Effect of Fodder Tree Species with Condensed Tannin Contents on In vitro Methane Production. Asian-Australas J Anim Sci. 2016 Jan;29(1):73-9. doi: 10.5713/ajas.15.0464. PMID: 26732330; PMCID: PMC4698691.
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Ruthenium(II)-Catalyzed C-H Oxygenations of Reusable Sulfoximine Benzamides.

Organic letters

Raghuvanshi K, Zell D, Ackermann L.
PMID: 28234011
Org Lett. 2017 Mar 17;19(6):1278-1281. doi: 10.1021/acs.orglett.6b03898. Epub 2017 Feb 24.

C-H oxygenations of synthetically meaningful sulfoximine benzamides were accomplished by a versatile ruthenium catalysis regime. The ruthenium(II) catalyst was characterized by excellent mono- and chemoselectivity as well as positional selectivity via facile base-assisted intramolecular electrophilic substitution-type (BIES) C-H activation....

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Raghuvanshi K, Zell D, Ackermann L. Ruthenium(II)-Catalyzed C-H Oxygenations of Reusable Sulfoximine Benzamides. Org Lett. 2017;19(6):1278-1281doi: 10.1021/acs.orglett.6b03898.
Raghuvanshi, K., Zell, D., & Ackermann, L. (2017). Ruthenium(II)-Catalyzed C-H Oxygenations of Reusable Sulfoximine Benzamides. Organic letters, 19(6), 1278-1281. https://doi.org/10.1021/acs.orglett.6b03898
Raghuvanshi, Keshav, et al. "Ruthenium(II)-Catalyzed C-H Oxygenations of Reusable Sulfoximine Benzamides." Organic letters vol. 19,6 (2017): 1278-1281. doi: https://doi.org/10.1021/acs.orglett.6b03898
Raghuvanshi K, Zell D, Ackermann L. Ruthenium(II)-Catalyzed C-H Oxygenations of Reusable Sulfoximine Benzamides. Org Lett. 2017 Mar 17;19(6):1278-1281. doi: 10.1021/acs.orglett.6b03898. Epub 2017 Feb 24. PMID: 28234011.
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Ir(III)-Catalyzed Carbenoid Functionalization of Benzamides: Synthesis of N-Methoxyisoquinolinediones and N-Methoxyisoquinolinones.

Organic letters

Phatake RS, Patel P, Ramana CV.
PMID: 27227376
Org Lett. 2016 Jun 17;18(12):2828-31. doi: 10.1021/acs.orglett.6b01072. Epub 2016 May 26.

A mild and efficient Ir(III)-catalyzed C-H carbenoid functionalization strategy has been developed to access N-methoxyisoquinolinediones and N-methoxyisoquinolinones. The reaction proceeds efficiently in high yield at room temperature over a broad range of substrates without requirement of any additional oxidants...

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Phatake RS, Patel P, Ramana CV. Ir(III)-Catalyzed Carbenoid Functionalization of Benzamides: Synthesis of N-Methoxyisoquinolinediones and N-Methoxyisoquinolinones. Org Lett. 2016;18(12):2828-31doi: 10.1021/acs.orglett.6b01072.
Phatake, R. S., Patel, P., & Ramana, C. V. (2016). Ir(III)-Catalyzed Carbenoid Functionalization of Benzamides: Synthesis of N-Methoxyisoquinolinediones and N-Methoxyisoquinolinones. Organic letters, 18(12), 2828-31. https://doi.org/10.1021/acs.orglett.6b01072
Phatake, Ravindra S, et al. "Ir(III)-Catalyzed Carbenoid Functionalization of Benzamides: Synthesis of N-Methoxyisoquinolinediones and N-Methoxyisoquinolinones." Organic letters vol. 18,12 (2016): 2828-31. doi: https://doi.org/10.1021/acs.orglett.6b01072
Phatake RS, Patel P, Ramana CV. Ir(III)-Catalyzed Carbenoid Functionalization of Benzamides: Synthesis of N-Methoxyisoquinolinediones and N-Methoxyisoquinolinones. Org Lett. 2016 Jun 17;18(12):2828-31. doi: 10.1021/acs.orglett.6b01072. Epub 2016 May 26. PMID: 27227376.
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Ruthenium-Catalyzed C-H Benzoxylation of tert-Benzamides with Aromatic Acids by Weak Coordination.

The Journal of organic chemistry

More NY, Padala K, Jeganmohan M.
PMID: 29087195
J Org Chem. 2017 Dec 01;82(23):12691-12700. doi: 10.1021/acs.joc.7b02495. Epub 2017 Nov 15.

A highly regioselective C-H benzoxylation of tertiary benzamides with aromatic acids by weak O-amide coordination in the presence of [{RuCl

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More NY, Padala K, Jeganmohan M. Ruthenium-Catalyzed C-H Benzoxylation of tert-Benzamides with Aromatic Acids by Weak Coordination. J Org Chem. 2017;82(23):12691-12700doi: 10.1021/acs.joc.7b02495.
More, N. Y., Padala, K., & Jeganmohan, M. (2017). Ruthenium-Catalyzed C-H Benzoxylation of tert-Benzamides with Aromatic Acids by Weak Coordination. The Journal of organic chemistry, 82(23), 12691-12700. https://doi.org/10.1021/acs.joc.7b02495
More, Nagnath Yadav, et al. "Ruthenium-Catalyzed C-H Benzoxylation of tert-Benzamides with Aromatic Acids by Weak Coordination." The Journal of organic chemistry vol. 82,23 (2017): 12691-12700. doi: https://doi.org/10.1021/acs.joc.7b02495
More NY, Padala K, Jeganmohan M. Ruthenium-Catalyzed C-H Benzoxylation of tert-Benzamides with Aromatic Acids by Weak Coordination. J Org Chem. 2017 Dec 01;82(23):12691-12700. doi: 10.1021/acs.joc.7b02495. Epub 2017 Nov 15. PMID: 29087195.
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Direct Amidation of N-Boc- and N-Cbz-Protected Amines via Rhodium-Catalyzed Coupling of Arylboroxines and Carbamates.

Organic letters

Lim DS, Lew TT, Zhang Y.
PMID: 26605554
Org Lett. 2015 Dec 18;17(24):6054-7. doi: 10.1021/acs.orglett.5b03061. Epub 2015 Nov 25.

N-Boc- and N-Cbz-protected amines are directly converted into amides by a novel rhodium-catalyzed coupling of arylboroxines and carbamates, replacing the traditional two-step deprotection-condensation sequence. Both protected anilines and aliphatic amines are efficiently transformed into a wide variety of secondary...

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Lim DS, Lew TT, Zhang Y. Direct Amidation of N-Boc- and N-Cbz-Protected Amines via Rhodium-Catalyzed Coupling of Arylboroxines and Carbamates. Org Lett. 2015;17(24):6054-7doi: 10.1021/acs.orglett.5b03061.
Lim, D. S., Lew, T. T., & Zhang, Y. (2015). Direct Amidation of N-Boc- and N-Cbz-Protected Amines via Rhodium-Catalyzed Coupling of Arylboroxines and Carbamates. Organic letters, 17(24), 6054-7. https://doi.org/10.1021/acs.orglett.5b03061
Lim, Diane S W, et al. "Direct Amidation of N-Boc- and N-Cbz-Protected Amines via Rhodium-Catalyzed Coupling of Arylboroxines and Carbamates." Organic letters vol. 17,24 (2015): 6054-7. doi: https://doi.org/10.1021/acs.orglett.5b03061
Lim DS, Lew TT, Zhang Y. Direct Amidation of N-Boc- and N-Cbz-Protected Amines via Rhodium-Catalyzed Coupling of Arylboroxines and Carbamates. Org Lett. 2015 Dec 18;17(24):6054-7. doi: 10.1021/acs.orglett.5b03061. Epub 2015 Nov 25. PMID: 26605554.
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Showing 1 to 12 of 632 entries