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Showing 1 to 5 of 5 entries
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Synthesis and characterisation of first row transition metal complexes of functionalized 1,2,4-benzothiadiazines.

Dalton transactions (Cambridge, England : 2003)

Clark ER, Anwar MU, Leontowicz BJ, Beldjoudi Y, Hayward JJ, Chan WT, Gavey EL, Pilkington M, Zysman-Colman E, Rawson JM.
PMID: 25030211
Dalton Trans. 2014 Sep 14;43(34):12996-3005. doi: 10.1039/c4dt01413h.

Reaction of the novel ligand 3-(2'-pyridyl)-benzo-1,2,4-thiadiazine (L) with the transition metal chloride salts MCl2·xH2O (M(II) = Mn, Fe, Co, Cu and Zn) in a 2 : 1 mole ratio afforded the mononuclear octahedral (high spin) complexes L2MCl2 (1a-1e respectively)...

Measurement of acidity constants of benzothiadiazines by solvent extraction with use of a membrane phase-separator.

Talanta

Khan AS, Cantwell FF.
PMID: 18964047
Talanta. 1986 Feb;33(2):119-23. doi: 10.1016/0039-9140(86)80027-3.

For extraction studies a "filter-probe" porous Teflon membrane phase-separator is used in conjunction with a spectrophotometer fitted with a small-volume flow-cell and a peristaltic pump to measure absorbance of the organic phase as a function of aqueous phase pH....

Spectrophotometric determination of benzothiadiazines in dosage forms.

Talanta

Belal F, Rizk M, Ibrahiem F, El-Din MS.
PMID: 18964056
Talanta. 1986 Feb;33(2):170-2. doi: 10.1016/0039-9140(86)80036-4.

The analytical utility of ethyl acetoacetate for the spectrophotometric determination of benzothiadiazine diuretics has been studied. The procedure developed is based on coupling of the diazotized drugs with the reagent, which possesses an active methylene group. The stoichiometry of...

Copper-promoted aerial oxidation of benzothiadiazines: access to benzothiadiazine S-oxide heterocycles.

Dalton transactions (Cambridge, England : 2003)

Clark ER, Hayward JJ, Leontowicz BJ, Anwar MU, Pilkington M, Rawson JM.
PMID: 25563651
Dalton Trans. 2015 Feb 07;44(5):2071-4. doi: 10.1039/c4dt03467h.

Cu(II)-promoted aerial oxidation of a series of benzothiadiazines () under ambient conditions affords the first structurally characterised examples of thiadiazine S-oxides (). The isolation of the homoleptic Cu(II) 3-(2'-pyridyl)benzothiadiazide-S-oxide complex provides insight into the reaction mechanism.

5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors.

ACS medicinal chemistry letters

Battisti UM, Jozwiak K, Cannazza G, Puia G, Stocca G, Braghiroli D, Parenti C, Brasili L, Carrozzo MM, Citti C, Troisi L.
PMID: 24900368
ACS Med Chem Lett. 2011 Nov 14;3(1):25-9. doi: 10.1021/ml200184w. eCollection 2012 Jan 12.

The potential therapeutic benefit of compounds able to activate AMPA receptors (AMPAr) has led to the search for new AMPAr positive modulators. On the basis of crystallographic data of the benzothiadiazines binding mode in the S1S2 GluA2 dimer interface,...

Showing 1 to 5 of 5 entries