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Showing 1 to 12 of 518 entries
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Antidepressant Potential of 5-HT3 Receptor Antagonist, N-n- propyl-3-ethoxyquinoxaline-2-carboxamide (6n).

Journal of young pharmacists : JYP

Mahesh R, Bhatt S, Devadoss T, Jindal A, Gautam B, Pandey D.
PMID: 23493308
J Young Pharm. 2012 Oct;4(4):235-44. doi: 10.4103/0975-1483.104367.

The present study was designed to evaluate the antidepressant potential of 5-HT3 receptor antagonist N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n). The compound '6n' with optimum log P and pA 2 value identified from a series of compounds synthesized in our laboratory was subjected...

Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats.

International journal of clinical and experimental medicine

Cai J, Ma J, Xu K, Gao G, Xiang Y, Lin C.
PMID: 26309650
Int J Clin Exp Med. 2015 Jun 15;8(6):9737-43. eCollection 2015.

Radix Sophorae Tonkinensis (S. tonkinensis) is the processed lateral root of Sophora subprostrata (Leguminosae) that widely distributed over the southwest China. Radix Sophorae Tonkinensis has been widely used as a Chinese medicinal herb for the treatment of disease such...

Bupropion Maintenance Treatment in Refractory Bipolar Depression: A Case Report.

Clinical practice and epidemiology in mental health : CP & EMH

Dehning J, Grunze H, Hausmann A.
PMID: 28659991
Clin Pract Epidemiol Ment Health. 2017 May 31;13:43-48. doi: 10.2174/1745017901713010043. eCollection 2017.

BACKGROUND: The optimal duration of antidepressant treatment in bipolar depression appears to be controversial due to a lack of quality evidence, and guideline recommendations are either vague or contradictive. This is especially true for second line treatments such as...

Weight loss medications in Canada - a new frontier or a repeat of past mistakes?.

Diabetes, metabolic syndrome and obesity : targets and therapy

Wharton S, Lee J, Christensen RA.
PMID: 29042804
Diabetes Metab Syndr Obes. 2017 Oct 04;10:413-417. doi: 10.2147/DMSO.S141571. eCollection 2017.

Current methods for the treatment of excess weight can involve healthy behavior changes, pharmacotherapy, and surgical interventions. Many individuals are able to lose some degree of weight through behavioral changes; however, they are often unable to maintain their weight...

How Relevant is Food Craving to Obesity and Its Treatment?.

Frontiers in psychiatry

Potenza MN, Grilo CM.
PMID: 25477827
Front Psychiatry. 2014 Nov 19;5:164. doi: 10.3389/fpsyt.2014.00164. eCollection 2014.

No abstract available.

The Accompanying Changes in Brain Structure of a Remitted Depression Patient with the Bupropion Treatment.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Hou YC, Lai CH.
PMID: 26598593
Clin Psychopharmacol Neurosci. 2015 Dec 31;13(3):319-20. doi: 10.9758/cpn.2015.13.3.319.

The impacts from the bupropion on the brain structures have seldom been mentioned in the literature. The bupropion is a kind of antidepressant with dual action in the norepinephrine and dopamine receptors. Here we have a case to share...

Stimulants for the Control of Hedonic Appetite.

Frontiers in pharmacology

Poulton AS, Hibbert EJ, Champion BL, Nanan RK.
PMID: 27199749
Front Pharmacol. 2016 Apr 25;7:105. doi: 10.3389/fphar.2016.00105. eCollection 2016.

The focus of this paper is treatment of obesity in relation to the management of hedonic appetite. Obesity is a complex condition which may be potentiated by excessive reward seeking in combination with executive functioning deficits that impair cognitive...

Naltrexone/Bupropion ER (Contrave): Newly Approved Treatment Option for Chronic Weight Management in Obese Adults.

P & T : a peer-reviewed journal for formulary management

Sherman MM, Ungureanu S, Rey JA.
PMID: 26957883
P T. 2016 Mar;41(3):164-72.

Naltrexone/bupropion ER (Contrave): newly approved treatment option for chronic weight management in obese adults.

Repurposing psychiatric medicines to target activated microglia in anxious mild cognitive impairment and early Parkinson's disease.

American journal of neurodegenerative disease

Lauterbach EC.
PMID: 27073741
Am J Neurodegener Dis. 2016 Mar 01;5(1):29-51. eCollection 2016.

Anxiety is common in the Mild Cognitive Impairment (MCI) stage of Alzheimer's disease (AD) and the pre-motor stages of Parkinson's disease (PD). A concomitant and possible cause of this anxiety is microglial activation, also considered a key promoter of...

Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs.

International journal of clinical and experimental medicine

Geng P, Wang S, Wang C, Chen J, Zhang L, Yang S, Wen C, Zhou Y, Zhang M.
PMID: 26885208
Int J Clin Exp Med. 2015 Dec 15;8(12):22310-8. eCollection 2015.

Flos Daturae, known as "baimantuoluo" or "yangjinhua" in China, has been used for centuries in Traditional Chinese Medicine for the treatment of asthma, convulsions, pain, and rheumatism. To investigate the influences of Flos Daturae on the activities of rat...

Therapy for Cessation of Smoking.

Medical journal, Armed Forces India

Bhattacharyya D, Rai SP, Neog LS.
PMID: 27408159
Med J Armed Forces India. 2008 Jul;64(3):254-9. doi: 10.1016/S0377-1237(08)80107-4. Epub 2011 Jul 21.

Tobacco dependence is a chronic relapsing medical illness. Unfortunately more than 1.1 billion people worldwide smoke tobacco. Tobacco consumption rate is very high in India. Providing three minutes counseling by physicians doubles the cessation rate as compared to no...

Strategies to promote smoking cessation among adolescents.

Paediatrics & child health

Harvey J, Chadi N.
PMID: 27429574
Paediatr Child Health. 2016 May;21(4):201-8. doi: 10.1093/pch/21.4.201.

In recent years, youth have been exposed to a broader spectrum of tobacco products including smokeless tobacco, hookah (water pipe) and e-cigarettes. Despite active local, provincial/territorial and national prevention strategies and legislated controls, thousands of teenagers develop an addiction...

Showing 1 to 12 of 518 entries