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Showing 1 to 12 of 1106 entries
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Effects of High-Dose Capsaicin on TMD Subjects: A Randomized Clinical Study.

JDR clinical and translational research

Campbell BK, Fillingim RB, Lee S, Brao R, Price DD, Neubert JK.
PMID: 28879245
JDR Clin Trans Res. 2017 Jan;2(1):58-65. doi: 10.1177/2380084416675837. Epub 2016 Oct 26.

Temporomandibular joint disorder (TMD) is a complex musculoskeletal disorder that presents with pain, limited jaw opening, and abnormal noises in the temporomandibular joint. Despite the significant impact that TMD has in terms of suffering and financial burden, relatively few...

Amitriptyline 2% cream vs. capsaicin 0.75% cream in the treatment of painful diabetic neuropathy (Double blind, randomized clinical trial of efficacy and safety).

Iranian journal of pharmaceutical research : IJPR

Kiani J, Ahmad Nasrollahi S, Esna-Ashari F, Fallah P, Sajedi F.
PMID: 26664395
Iran J Pharm Res. 2015;14(4):1263-8.

Because of less systemic side effects of topical medications in pain relief of the painful form of diabetic peripheral neuropathy, this study aimed to compare the effect of amitriptyline and capsaicin cream in relieving pain in this condition. In...

Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine.

The open pain journal

Iadarola MJ, Gonnella GL.
PMID: 26779292
Open Pain J. 2013;6:95-107. doi: 10.2174/1876386301306010095. Epub 2013 Mar 08.

This review examines existing preclinical and clinical studies related to resiniferatoxin (RTX) and its potential uses in pain treatment. Like capsaicin, RTX is a vanilloid receptor (TRPV1) agonist, only more potent. This increased potency confers both quantitative and qualitative...

Management of Neuropathic Pain Associated with Spinal Cord Injury.

Pain and therapy

Hagen EM, Rekand T.
PMID: 25744501
Pain Ther. 2015 Jun;4(1):51-65. doi: 10.1007/s40122-015-0033-y. Epub 2015 Mar 06.

Spinal cord injury (SCI) is an injury to the spinal cord that leads to varying degrees of motor and/or sensory deficits and paralysis. Chronic pain of both neuropathic and nociceptive type is common and contributes to reduced quality of...

Antinociceptive action of .

Avicenna journal of phytomedicine

Leite LI, Leite GO, Fernandes Silva BA, Gonçalves Sousa SD, Coutinho TS, Sampaio RS, Menezes I, Martins Costa JG, Campos AR.
PMID: 28265551
Avicenna J Phytomed. 2017 Jan-Feb;7(1):93-98.

MATERIALS AND METHODS: The antinociceptive activity was assessed using the capsaicin, glutamate, hot plate and cold allodynia tests. The antipuritic effects were also verified based on histamine-induced scratching behavior.RESULTS: EOVA reduced the paw licking induced by capsaicin, but not...

Capsaicin reverses the inhibitory effect of licochalcone A/β-Arbutin on tyrosinase expression in b16 mouse melanoma cells.

Pharmacognosy magazine

Hong JH, Chen HJ, Xiang SJ, Cao SW, An BC, Ruan SF, Zhang B, Weng LD, Zhu HX, Liu Q.
PMID: 29576710
Pharmacogn Mag. 2018 Jan-Mar;14(53):110-115. doi: 10.4103/pm.pm_103_17. Epub 2018 Feb 20.

INTRODUCTION: Melanin is synthesized by melanocytes, which are located in the basal layer of the skin. After synthesis, melanin is further deposited on the surface of the skin to form black spots or chloasma. Tyrosinase is a rate-limiting enzyme...

The effect of the electrophilic fatty acid nitro-oleic acid on TRP channel function in sensory neurons.

Nitric oxide : biology and chemistry

Beckel JM, de Groat WC.
PMID: 29578059
Nitric Oxide. 2018 Mar 22; doi: 10.1016/j.niox.2018.03.015. Epub 2018 Mar 22.

Nitro-oleic acid (NO

Asthma-like airway inflammation and responses in a rat model of atopic dermatitis induced by neonatal capsaicin treatment.

Journal of asthma and allergy

Han RT, Kim S, Choi K, Jwa H, Lee J, Kim HY, Kim HJ, Kim HR, Back SK, Na HS.
PMID: 28572736
J Asthma Allergy. 2017 May 18;10:181-189. doi: 10.2147/JAA.S124902. eCollection 2017.

Recent studies have shown that approximately 70% of patients with severe atopic dermatitis (AD) develop asthma. Development of AD in infancy and subsequent other atopic diseases such as asthma in childhood is referred to as atopic march. However, a...

Perception of chemesthetic stimuli in groups who differ by food involvement and culinary experience.

Food quality and preference

Byrnes N, Loss CR, Hayes JE.
PMID: 26516297
Food Qual Prefer. 2015 Dec 01;46:142-150. doi: 10.1016/j.foodqual.2015.07.017.

In the English language, there is generally a limited lexicon when referring to the sensations elicited by chemesthetic stimuli like capsaicin, allyl isothiocyanate, and eugenol, the orally irritating compounds found in chiles, wasabi, and cloves, respectively. Elsewhere, experts and...

Food & nutrition research

Wu S, Pan H, Tan S, Ding C, Huang G, Liu G, Guo J, Su Z.
PMID: 28659743
Food Nutr Res. 2017 Jun 14;61(1):1331658. doi: 10.1080/16546628.2017.1331658. eCollection 2017.

Chitosan and capsaicin are compounds extracted from natural products and have been indicated to lower body weight and prevent fatty liver. However, their applications are limited by poor oral bioavailability, low compliance and some serious side effects. To solve...

Capsaicin-Inspired Thiol-Ene Terpolymer Networks Designed for Antibiofouling Coatings.

Langmuir : the ACS journal of surfaces and colloids

Wang H, Jasensky J, Ulrich NW, Cheng J, Huang H, Chen Z, He C.
PMID: 29100465
Langmuir. 2017 Nov 28;33(47):13689-13698. doi: 10.1021/acs.langmuir.7b03098. Epub 2017 Nov 16.

Novel photocurable ternary polymer networks were prepared by incorporating N-(4-hydroxy-3-methoxybenzyl)-acrylamide (HMBA) into a cross-linked thiol-ene network based on poly(ethylene glycol)diacrylate (PEGDA) and (mercaptopropyl)methylsiloxane homopolymers (MSHP). The ternary network materials displayed bactericidal activity against Escherichia coli and Staphylococcus aureus and...

Protective effect of (-)-epigallocatechin-3-gallate on capsaicin-induced DNA damage and oxidative stress in human erythrocyes and leucocytes in vitro.

Cytotechnology

Pandır D.
PMID: 24728932
Cytotechnology. 2015 Mar;67(2):367-77. doi: 10.1007/s10616-014-9695-2. Epub 2014 Apr 13.

The aim of this study is to show that protective effects of the main catechin (-)-epigallocatechin-3-gallate (EGCG) against capsaicin (CAP) induced oxidative stress and DNA damage in human blood in vitro. Superoxide dismutase, catalase, glutathione peroxidase and malondialdehyde (MDA)...

Showing 1 to 12 of 1106 entries