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Showing 1 to 12 of 3919 entries
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Application of sustained delivery microsphere of cyclosporine A for preventing posterior capsular opacification in rabbits.

International journal of ophthalmology

Pei C, Xu Y, Jiang JX, Cui LJ, Li L, Qin L.
PMID: 23550193
Int J Ophthalmol. 2013;6(1):1-7. doi: 10.3980/j.issn.2222-3959.2013.01.01. Epub 2013 Feb 18.

AIM: To explore the inhibitory effect of a sustained cyclosporin A (CsA) delivery microsphere (CsA-MS) on posterior capsular opacification (PCO) in rabbit eyes after cataract extraction.METHODS: Twenty New Zealand white rabbits accepted cataract extraction plus intraocular lens implantation and...

Identifying, highlighting and reducing polypharmacy in a UK hospice inpatient unit using improvement Science methods.

BMJ quality improvement reports

Phippen A, Pickard J, Steinke D, Cope M, Roberts D.
PMID: 28321300
BMJ Qual Improv Rep. 2017 Mar 10;6(1). doi: 10.1136/bmjquality.u211783.w5035. eCollection 2017.

Polypharmacy, the concurrent use of multiple medications by one individual is a growing global issue driven by an ageing population and increasing prevalence of multi-morbidity[1]. Polypharmacy can be problematic: interactions between medications, reduced adherence to medication, burden of medication...

Light-responsive molecular containers.

Chemical communications (Cambridge, England)

Díaz-Moscoso A, Ballester P.
PMID: 28382335
Chem Commun (Camb). 2017 Apr 25;53(34):4635-4652. doi: 10.1039/c7cc01568b.

Encapsulation of small molecules in molecular containers able to release them in a controlled way in order to perform specific tasks (e.g. catalysis or drug delivery) constitutes an idea that has been around for several years. Light is becoming...

A randomized, double-blind, placebo-controlled, cross-over study to evaluate analgesic activity of Terminalia chebula in healthy human volunteers using a mechanical pain model.

Journal of anaesthesiology, clinical pharmacology

Pokuri VK, Kumar CU, Pingali U.
PMID: 27625480
J Anaesthesiol Clin Pharmacol. 2016 Jul-Sep;32(3):329-32. doi: 10.4103/0970-9185.173365.

BACKGROUND AND AIMS: To evaluate analgesic activity and safety of single oral dose (1000 mg) of Terminalia chebula using a mechanical pain model in healthy human volunteers.MATERIAL AND METHODS: Twelve healthy volunteers were randomized to receive either single oral...

[Light and scanning electron microscopy of anterior lens capsule following different capsulorhexis techniques].

Vestnik oftalmologii

Avetisov KS, Fеdorov AA, Novikov IA.
PMID: 26977720
Vestn Oftalmol. 2015 Nov-Dec;131(6):4-10. doi: 10.17116/oftalma201513164-10.

UNLABELLED: Aim - to assess the morphology of anterior lens capsules following circular capsulorhexis, for which capsulotomy was either manual or femtosecond (FS) laser produced.MATERIAL AND METHODS: A total of 30 capsular samples obtained during phacoemulsification surgery were studied...

Encapsulation of spherical nanoparticles by colloidal dimers.

Physical chemistry chemical physics : PCCP

Munaò G, Costa D, Prestipino S, Caccamo C.
PMID: 27538707
Phys Chem Chem Phys. 2016 Sep 28;18(36):24922-30. doi: 10.1039/c6cp04704a. Epub 2016 Aug 19.

We study by Monte Carlo simulation the coating process of colloidal dimers onto spherical nanoparticles. To this end we investigate a simplified mixture of hard spheres (the guest particles) and hard dimers formed by two tangent spheres of different...

Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea: A Randomized, Double-Masked, Placebo-Controlled Trial.

Open forum infectious diseases

Ehrhardt S, Guo N, Hinz R, Schoppen S, May J, Reiser M, Schroeder MP, Schmiedel S, Keuchel M, Reisinger EC, Langeheinecke A, de Weerth A, Schuchmann M, Schaberg T, Ligges S, Eveslage M, Hagen RM, Burchard GD, Lohse AW.
PMID: 26973849
Open Forum Infect Dis. 2016 Jan 29;3(1):ofw011. doi: 10.1093/ofid/ofw011. eCollection 2016 Jan.

Background.  Antibiotic-associated diarrhea (AAD) and Clostridium difficile-associated diarrhea (CDAD) are common complications of antibiotic use. Data on the efficacy of probiotics to prevent AAD and CDAD are unclear. We aimed to evaluate the efficacy of Saccharomyces boulardii to prevent...

Metal-Organic Framework for Emulsifying Carbon Dioxide and Water.

Angewandte Chemie (International ed. in English)

Liu C, Zhang J, Zheng L, Zhang J, Sang X, Kang X, Zhang B, Luo T, Tan X, Han B.
PMID: 27529754
Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11372-6. doi: 10.1002/anie.201602150. Epub 2016 Aug 16.

Forming emulsions of carbon dioxide (CO2 ) and water can largely expand the utility of CO2 . Herein we propose for the first time the utilization of a metal-organic framework (MOF) for emulsifying CO2 and water. Owing to the...

κ-Carrageenan/locust bean gum as hard capsule gelling agents.

Carbohydrate polymers

He H, Ye J, Zhang X, Huang Y, Li X, Xiao M.
PMID: 28917884
Carbohydr Polym. 2017 Nov 01;175:417-424. doi: 10.1016/j.carbpol.2017.07.049. Epub 2017 Jul 21.

A novel gelling agent, comprising blended κ-carrageenan (κ-C), a seaweed polysaccharide and locust bean gum (LBG), was used to prepare hard capsules. The distinct synergism between κ-C and LBG were verified by the textural profile analysis (TPA), FTIR and...

Evaluation of bioequivalence of five 0.1 mg dutasteride capsules compared to one 0.5 mg dutasteride capsule: a randomized study in healthy male volunteers.

Journal of drug assessment

Fossler MJ, Collins DA, Ino H, Sarai N, Ravindranath R, Bowen CL, Burns O.
PMID: 27536459
J Drug Assess. 2015 Jul 14;4(1):24-9. doi: 10.3109/21556660.2015.1067219. eCollection 2015.

OBJECTIVE: To evaluate the bioequivalence of five 0.1 mg dutasteride capsules to one 0.5 mg dutasteride capsule in healthy adult male subjects under fasting conditions.METHODS: This was a single-center, open-label, randomized, single dose, two-way cross-over study (ClinicalTrials.gov identifier NCT01929330)....

Cryopreservation the seeds of a Taiwanese terrestrial orchid, Bletilla formosana (Hayata) Schltr. by vitrification.

Botanical studies

Hu WH, Yang YH, Liaw SI, Chang C.
PMID: 28510879
Bot Stud. 2013 Dec;54(1):33. doi: 10.1186/1999-3110-54-33. Epub 2013 Sep 12.

BACKGROUND: The cryopreservation of orchid seeds is an important conservation method, studies of the effects of cryopreservation on the seeds of wild orchids are scant. This investigation was to establish a method for the vitrification and cryopreservation of seeds...

To catalyze or not to catalyze: elucidation of the subtle differences between the hexameric capsules of pyrogallolarene and resorcinarene.

Chemical science

Zhang Q, Catti L, Kaila VRI, Tiefenbacher K.
PMID: 28451294
Chem Sci. 2017 Feb 01;8(2):1653-1657. doi: 10.1039/c6sc04565k. Epub 2016 Nov 15.

The closely related, self-assembled resorcinarene and pyrogallolarene capsules display contrasting and puzzling encapsulation behaviors. Herein, we elucidate the reasons for these differences by combining experimental studies and DFT calculations. Furthermore, we report that, in contrast to the resorcinarene capsule,...

Showing 1 to 12 of 3919 entries