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Showing 1 to 10 of 10 entries
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The NO stimulator, Catestatin, improves the Frank-Starling response in normotensive and hypertensive rat hearts.

Nitric oxide : biology and chemistry

Angelone T, Quintieri AM, Pasqua T, Filice E, Cantafio P, Scavello F, Rocca C, Mahata SK, Gattuso A, Cerra MC.
PMID: 26241941
Nitric Oxide. 2015 Nov 15;50:10-19. doi: 10.1016/j.niox.2015.07.004. Epub 2015 Aug 01.

The myocardial response to mechanical stretch (Frank-Starling law) is an important physiological cardiac determinant. Modulated by many endogenous substances, it is impaired in the presence of cardiovascular pathologies and during senescence. Catestatin (CST:hCgA352-372), a 21-amino-acid derivate of Chromogranin A...

New continuous cell-line from human medullary-thyroid carcinoma - sinj - phenotypic analysis and invivo carcinogenesis.

International journal of oncology

Pfragner R, Wirnsberger G, Behmel A, Wolf G, Passath A, Ingolic E, Adamiker D, Schauenstein K.
PMID: 21573635
Int J Oncol. 1993 May;2(5):831-6. doi: 10.3892/ijo.2.5.831.

SINJ is a new continuous human cell line derived from a lymph node metastasis of a probably sporadic medullary thyroid carcinoma. It is compared to MTC-SK, another medullary thyroid carcinoma cell line, established earlier (1). SINJ has been continuously...

A novel stepwise integrative analysis pipeline reveals distinct microbiota-host interactions and link to symptoms in irritable bowel syndrome.

Scientific reports

Polster A, Öhman L, Tap J, Derrien M, Le Nevé B, Sundin J, Törnblom H, Cvijovic M, Simrén M.
PMID: 33750831
Sci Rep. 2021 Mar 09;11(1):5521. doi: 10.1038/s41598-021-84686-9.

Although incompletely understood, microbiota-host interactions are assumed to be altered in irritable bowel syndrome (IBS). We, therefore, aimed to develop a novel analysis pipeline tailored for the integrative analysis of microbiota-host interactions and association to symptoms and prove its...

Regulation of chromogranin a and chromogranin B (secretogranin I) synthesis in bovine cultured chromaffin cells.

Journal of neuroendocrinology

Galindo E, Bader MF, Aunis D.
PMID: 19215537
J Neuroendocrinol. 1991 Dec 01;3(6):669-77. doi: 10.1111/j.1365-2826.1991.tb00332.x.

Abstract In the present study we investigated the regulation of Chromogranin A (CGA) and Chromogranin B (CGB) biosynthesis in bovine chromaffin cells maintained in primary culture. Cellular proteins were labelled with [(35)S]methionine and the incorporated radioactivity was used as...

Chromogranins: Universal proteins in secretory organelles from paramecium to man.

Neurochemistry international

Helle KB.
PMID: 20504617
Neurochem Int. 1990;17(2):165-75. doi: 10.1016/0197-0186(90)90139-k.

The immunological approach to chromaffin granule research in the mid 1960s led to the discovery of the coexistence and cosecretion of chromogranins with catecholamine hormones and adenine nucleotides. Now three members of the chromogranin family of uniquely acidic proteins...

Distribution of mRNAs for Chromogranins A and B and Secretogranin II in Rat Brain.

The European journal of neuroscience

Mahata SK, Mahata M, Marksteiner J, Sperk G, Fischer-Colbrie R, Winkler H.
PMID: 12106456
Eur J Neurosci. 1991;3(9):895-904. doi: 10.1111/j.1460-9568.1991.tb00101.x.

The mRNA distribution of chromogranins A and B and secretogranin II was determined in rat brain. In Northern blots the oligonucleotide probes used hybridized with single mRNA species of the expected sizes. With tissue hybridization the mRNA signals for...

Soluble acidic lipoprotein components of adrenomedullary chromaffin granules. Relation to chromogranins.

FEBS letters

Mylroie R, Koenig H.
PMID: 11945556
FEBS Lett. 1971 Jan 12;12(3):121-124. doi: 10.1016/0014-5793(71)80048-0.

No abstract available.

Antiserum directed against chromogranin A and B (CAB) is a useful marker for peptide hormone-producing endocrine cells and tumors.

Endocrine pathology

Larsson L, Alumets J, Eriksson B, Håkanson R, Lundquist G, Öberg K, Sundler F.
PMID: 32138402
Endocr Pathol. 1992 Mar;3(1):14-22. doi: 10.1007/BF02921339.

Certain proteins, such as the chromogranins, have a ubiquitous occurrence in nearly ail peptide hormone-producing cells. To date, little is known about their functional role as structural proteins, precursors of bioactive peptides, or enzymes. Such proteins may serve as...

Synchronous large-cell neuroendocrine carcinoma and adenocarcinoma of the colon.

Gut and liver

Park JS, Kim L, Kim CH, Bang BW, Lee DH, Jeong S, Shin YW, Kim HG.
PMID: 20479925
Gut Liver. 2010 Mar;4(1):122-5. doi: 10.5009/gnl.2010.4.1.122. Epub 2010 Mar 30.

Large-cell neuroendocrine carcinoma of the colon is a rare entity with a prognosis that is usually poor due to the high likelihood of early metastasis. A 61-year-old man had surgery for colon cancer of the transverse colon and cecum....

Histopathological Chromogranin A-Positivity Is Associated with Right-Sided Colorectal Cancers and Worse Prognosis.

Cancers

Herold Z, Dank M, Herold M, Nagy P, Rosta K, Somogyi A.
PMID: 33383764
Cancers (Basel). 2020 Dec 29;13(1). doi: 10.3390/cancers13010067.

BACKGROUND: Colorectal cancer (CRC) is known to be affected by paraneoplastic thrombocytosis and chromogranin A-positive neuroendocrine-cell differentiation (CgAMETHODS: A prospective cohort pilot study of 42 CRC patients and 42 age- and sex-matched controls was carried out. Plasma interleukin-6, thrombopoietin,...

Showing 1 to 10 of 10 entries