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Showing 1 to 12 of 55 entries
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Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis.

Evidence-based complementary and alternative medicine : eCAM

Xi SY, Teng YH, Chen Y, Li JP, Zhang YY, Liu SL, Zou X, Zhou JY, Wu J, Wang RP.
PMID: 26457107
Evid Based Complement Alternat Med. 2015;2015:236506. doi: 10.1155/2015/236506. Epub 2015 Sep 17.

Jianpi Huayu Decoction (JHD), a Chinese medicine formula, is a typical prescription against multiple tumors in the clinical treatment, which can raise quality of life and decrease complications. The aim of this study is to assess the efficacy of...

Correlation between the protein expression of A-kinase anchor protein 95, cyclin D3 and AKT and pathological indicators in lung cancer tissues.

Experimental and therapeutic medicine

Yu X, Yuan Y, Zhi X, Teng B, Chen X, Huang Q, Chen Y, Guan Z, Zhang Y.
PMID: 26622460
Exp Ther Med. 2015 Sep;10(3):1175-1181. doi: 10.3892/etm.2015.2637. Epub 2015 Jul 15.

The aim of the present study was to investigate the correlation between the protein expression of A-kinase anchor protein 95 (AKAP95), cyclin D3 and AKT with pathological indicators in lung cancer tissues. Immunohistochemistry was used to detect the protein...

Cyclin D3 predicts disease-free survival in breast cancer.

Cancer cell international

Chi Y, Huang S, Liu M, Guo L, Shen X, Wu J.
PMID: 26412984
Cancer Cell Int. 2015 Sep 26;15:89. doi: 10.1186/s12935-015-0245-6. eCollection 2015.

BACKGROUND: Cyclin D3, which induces progression through the G1 phase of the cell cycle, is a regulator of Cyclin-dependent kinases 4 and 6. Previous studies revealed that abnormal expression of Cyclin D3 was found in many different cancers. However,...

Comparative proteome profiling of MCF10A and 184A1 human breast epithelial cells emphasized involvement of CDK4 and cyclin D3 in cell proliferation.

Proteomics. Clinical applications

Bhaskaran N, Lin KW, Gautier A, Woksepp H, Hellman U, Souchelnytskyi S.
PMID: 21136936
Proteomics Clin Appl. 2009 Jan;3(1):68-77. doi: 10.1002/prca.200800045. Epub 2008 Nov 20.

Acquiring high proliferation rate is crucial for carcinogenic transformation of cells. We report here proteome profiling of human breast epithelial cells with low (184A1) and high (MCF10A) proliferation rates. We identified 183 proteins in 184A1 and 318 proteins in...

SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells.

Oncogenesis

Herreros-Villanueva M, Zhang JS, Koenig A, Abel EV, Smyrk TC, Bamlet WR, de Narvajas AA, Gomez TS, Simeone DM, Bujanda L, Billadeau DD.
PMID: 23917223
Oncogenesis. 2013 Aug 05;2:e61. doi: 10.1038/oncsis.2013.23.

SOX2 (Sex-determining region Y (SRY)-Box2) has important functions during embryonic development and is involved in cancer stem cell (CSC) maintenance, in which it impairs cell growth and tumorigenicity. However, the function of SOX2 in pancreatic cancer cells is unclear....

Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest.

Evidence-based complementary and alternative medicine : eCAM

Wang TC, Fang CN, Shen CC, Wei HY, Weng YP, Lin JY, Hsieh-Li HM, Lee CY.
PMID: 22693529
Evid Based Complement Alternat Med. 2012;2012:276032. doi: 10.1155/2012/276032. Epub 2012 May 30.

Lung cancer has long been one of the most deadly forms of cancer. The majority of lung cancers are of the non-small-cell lung cancer (NSCLC) type. Here we used the non-small-cell lung carcinoma cell line A549 to screen 15...

The Mammalian Peptide Adrenomedullin Acts as a Growth Factor in Tobacco Plants.

Frontiers in physiology

Peláez R, Niculcea M, Martínez A.
PMID: 28446879
Front Physiol. 2017 Apr 12;8:219. doi: 10.3389/fphys.2017.00219. eCollection 2017.

Growth factors are extracellular signals that regulate cell proliferation and total body mass. Some animal growth factors can work on plant tissues and vice versa. Here we show that the mammalian growth factor adrenomedullin (AM) induces growth in tobacco...

Effect of TLR2 on the proliferation of inflammation-related colorectal cancer and sporadic colorectal cancer.

Cancer cell international

Meng S, Li Y, Zang X, Jiang Z, Ning H, Li J.
PMID: 32256204
Cancer Cell Int. 2020 Mar 30;20:95. doi: 10.1186/s12935-020-01184-0. eCollection 2020.

BACKGROUND: Colitis-associated cancer (CAC) is a complication of inflammatory bowel disease (IBD) with a poor prognosis because it is often diagnosed in advanced stages with local progression or metastasis. Compared with the more common polyp-induced sporadic colorectal cancer (sCRC),...

MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment.

Frontiers in cell and developmental biology

Song N, Li P, Song P, Li Y, Zhou S, Su Q, Li X, Yu Y, Li P, Feng M, Zhang M, Lin W.
PMID: 32754587
Front Cell Dev Biol. 2020 Jul 10;8:540. doi: 10.3389/fcell.2020.00540. eCollection 2020.

Non-small cell lung cancer (NSCLC) is still challenging for treatment owing to immune tolerance and evasion. MicroRNA-138 (miR-138) not only acts as a tumor suppressor to inhibit tumor cell proliferation and migration but also regulates immune response. The regulatory...

A Review on Splenic Diffuse Red Pulp Small B-Cell Lymphoma.

Current oncology (Toronto, Ont.)

Yilmaz E, Chhina A, Nava VE, Aggarwal A.
PMID: 34940070
Curr Oncol. 2021 Dec 06;28(6):5148-5154. doi: 10.3390/curroncol28060431.

Splenic diffuse red pulp small B-cell lymphoma (SDRPL) is a rare disease, representing

Epstein-Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features.

British journal of haematology

Richter J, John K, Staiger AM, Rosenwald A, Kurz K, Michgehl U, Ott G, Franzenburg S, Kohler C, Finger J, Oschlies I, Paul U, Siebert R, Spang R, Burkhardt B, Klapper W.
PMID: 34617271
Br J Haematol. 2021 Oct 06; doi: 10.1111/bjh.17874. Epub 2021 Oct 06.

Sporadic Burkitt lymphoma (BL) is the most frequent tumour of children and adolescents but a rare subtype of lymphomas in adults. To date most molecular data have been obtained from lymphomas arising in the young. Recently, Epstein-Barr virus (EBV)...

Rational drug combinations with CDK4/6 inhibitors in acute lymphoblastic Leukemia.

Haematologica

Bride KL, Hu H, Tikhonova A, Fuller TJ, Vincent TL, Shraim R, Li MM, Carroll WL, Raetz EA, Aifantis I, Teachey DT.
PMID: 34937317
Haematologica. 2021 Dec 23; doi: 10.3324/haematol.2021.279410. Epub 2021 Dec 23.

Despite improvements in outcomes for children with B and T-cell acute lymphoblastic leukemia (B-ALL and T-ALL), patients with resistant or relapsed disease fare poorly. Previous studies have demonstrated the essential role of cyclin D3 in T-ALL disease initiation and...

Showing 1 to 12 of 55 entries