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Showing 1 to 12 of 69 entries
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The effects of cyclooxygenase inhibitors on the brain inflammatory response following traumatic brain injury in rats.

Iranian journal of basic medical sciences

Keshavarzi Z, Khaksari M, Razmi Z, Soltani Hekmat A, Naderi V, Rostami S.
PMID: 23492757
Iran J Basic Med Sci. 2012 Sep;15(5):1102-5.

OBJECTIVES: Cytokines such as IL-1β are involved in inflammatory responses. This study evaluated the role of two different kinds of drugs (ibuprofen and celecoxib) on brain IL-10 and IL-1β after traumatic brain injury (TBI) in male rats.MATERIALS AND METHODS:...

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Keshavarzi Z, Khaksari M, Razmi Z, et al. The effects of cyclooxygenase inhibitors on the brain inflammatory response following traumatic brain injury in rats. Iran J Basic Med Sci. 2012;15(5):1102-5
Keshavarzi, Z., Khaksari, M., Razmi, Z., Soltani Hekmat, A., Naderi, V., & Rostami, S. (2012). The effects of cyclooxygenase inhibitors on the brain inflammatory response following traumatic brain injury in rats. Iranian journal of basic medical sciences, 15(5), 1102-5.
Keshavarzi, Zakieh, et al. "The effects of cyclooxygenase inhibitors on the brain inflammatory response following traumatic brain injury in rats." Iranian journal of basic medical sciences vol. 15,5 (2012): 1102-5.
Keshavarzi Z, Khaksari M, Razmi Z, Soltani Hekmat A, Naderi V, Rostami S. The effects of cyclooxygenase inhibitors on the brain inflammatory response following traumatic brain injury in rats. Iran J Basic Med Sci. 2012 Sep;15(5):1102-5. PMID: 23492757; PMCID: PMC3586930.
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Etoricoxib-induced pretibial erythema and edema.

Indian dermatology online journal

Kumar P.
PMID: 26904451
Indian Dermatol Online J. 2015 Dec;6:S47-9. doi: 10.4103/2229-5178.171046.

Cyclooxygenase inhibitors were developed in the quest of enhanced analgesic efficacy devoid of gastric side effects. Etoricoxib is a second-generation cox-2 inhibitor and as its use increases so do the reports of side effects. We report a case of...

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Kumar P. Etoricoxib-induced pretibial erythema and edema. Indian Dermatol Online J. 2015;6:S47-9doi: 10.4103/2229-5178.171046.
Kumar, P. (2015). Etoricoxib-induced pretibial erythema and edema. Indian dermatology online journal, 6S47-9. https://doi.org/10.4103/2229-5178.171046
Kumar, Pramod. "Etoricoxib-induced pretibial erythema and edema." Indian dermatology online journal vol. 6 (2015): S47-9. doi: https://doi.org/10.4103/2229-5178.171046
Kumar P. Etoricoxib-induced pretibial erythema and edema. Indian Dermatol Online J. 2015 Dec;6:S47-9. doi: 10.4103/2229-5178.171046. PMID: 26904451; PMCID: PMC4738517.
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Reversal of high dietary fructose-induced PPARalpha suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors.

Nutrition & metabolism

Kelley GL, Azhar S.
PMID: 16091142
Nutr Metab (Lond). 2005 Aug 09;2:18. doi: 10.1186/1743-7075-2-18.

High fructose feeding causes diet-induced alterations of lipid metabolism and decreased insulin sensitivity, hallmark of which is a rapid and profound hypertriglyceridemia. One of the mechanisms that contribute to serum hypertriglyceridemia in this model is suppression of hepatic PPARalpha....

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Kelley GL, Azhar S. Reversal of high dietary fructose-induced PPARalpha suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors. Nutr Metab (Lond). 2005;2:18doi: 10.1186/1743-7075-2-18.
Kelley, G. L., & Azhar, S. (2005). Reversal of high dietary fructose-induced PPARalpha suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors. Nutrition & metabolism, 218. https://doi.org/10.1186/1743-7075-2-18
Kelley, Glen L, and Azhar, Salman. "Reversal of high dietary fructose-induced PPARalpha suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors." Nutrition & metabolism vol. 2 (2005): 18. doi: https://doi.org/10.1186/1743-7075-2-18
Kelley GL, Azhar S. Reversal of high dietary fructose-induced PPARalpha suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors. Nutr Metab (Lond). 2005 Aug 09;2:18. doi: 10.1186/1743-7075-2-18. PMID: 16091142; PMCID: PMC1188072.
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Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells.

Biomarker insights

Brust AK, Ulbrich HK, Seigel GM, Pfeiffer N, Grus FH.
PMID: 19578520
Biomark Insights. 2008 Jul 08;3:387-402. doi: 10.4137/bmi.s692.

Glaucoma is characterized by a loss of retinal ganglion cells (RGC) which is associated with a decrease of visual function. Neuroprotective agents as a new therapeutic strategy could prevent the remaining neurons from apoptotic cell death. Previous studies have...

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Brust AK, Ulbrich HK, Seigel GM, et al. Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells. Biomark Insights. 2008;3:387-402doi: 10.4137/bmi.s692.
Brust, A. K., Ulbrich, H. K., Seigel, G. M., Pfeiffer, N., & Grus, F. H. (2008). Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells. Biomarker insights, 3387-402. https://doi.org/10.4137/bmi.s692
Brust, Anja-Kristina, et al. "Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells." Biomarker insights vol. 3 (2008): 387-402. doi: https://doi.org/10.4137/bmi.s692
Brust AK, Ulbrich HK, Seigel GM, Pfeiffer N, Grus FH. Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells. Biomark Insights. 2008 Jul 08;3:387-402. doi: 10.4137/bmi.s692. PMID: 19578520; PMCID: PMC2688370.
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Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells.

Immune network

Kim HJ, Lee YH, Im SA, Kim K, Lee CK.
PMID: 20631879
Immune Netw. 2010 Jun;10(3):92-8. doi: 10.4110/in.2010.10.3.92. Epub 2010 Jun 30.

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve pain, reduce fever and inhibit inflammation. NSAIDs function mainly through inhibition of cyclooxygenase (COX). Growing evidence suggests that NSAIDs also have immunomodulatory effects on T and B cells. Here...

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Kim HJ, Lee YH, Im SA, et al. Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells. Immune Netw. 2010;10(3):92-8doi: 10.4110/in.2010.10.3.92.
Kim, H. J., Lee, Y. H., Im, S. A., Kim, K., & Lee, C. K. (2010). Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells. Immune network, 10(3), 92-8. https://doi.org/10.4110/in.2010.10.3.92
Kim, Hyun-Jin, et al. "Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells." Immune network vol. 10,3 (2010): 92-8. doi: https://doi.org/10.4110/in.2010.10.3.92
Kim HJ, Lee YH, Im SA, Kim K, Lee CK. Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells. Immune Netw. 2010 Jun;10(3):92-8. doi: 10.4110/in.2010.10.3.92. Epub 2010 Jun 30. PMID: 20631879; PMCID: PMC2902675.
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Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway.

Thrombosis journal

Topf HG, Rauh M, Rascher W, Dötsch J, Klinge JM.
PMID: 22564812
Thromb J. 2012 May 07;10(1):6. doi: 10.1186/1477-9560-10-6.

UNLABELLED: The clinical use of Sodium nitroprusside (SNP) may be associated with an alteration of platelet function. The main focus of this study was the effect of SNP on platelet aggregation in the absence or presence of endothelial cells.METHODS:...

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Topf HG, Rauh M, Rascher W, et al. Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway. Thromb J. 2012;10(1):6doi: 10.1186/1477-9560-10-6.
Topf, H. G., Rauh, M., Rascher, W., Dötsch, J., & Klinge, J. M. (2012). Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway. Thrombosis journal, 10(1), 6. https://doi.org/10.1186/1477-9560-10-6
Topf, Hans-Georg, et al. "Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway." Thrombosis journal vol. 10,1 (2012): 6. doi: https://doi.org/10.1186/1477-9560-10-6
Topf HG, Rauh M, Rascher W, Dötsch J, Klinge JM. Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway. Thromb J. 2012 May 07;10(1):6. doi: 10.1186/1477-9560-10-6. PMID: 22564812; PMCID: PMC3528661.
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Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts.

Oncology letters

Li W, Tang YX, Wan L, Cai JH, Zhang J.
PMID: 23426648
Oncol Lett. 2013 Mar;5(3):923-928. doi: 10.3892/ol.2012.1086. Epub 2012 Dec 19.

The present study aimed to investigate the combined effects of Taxol and cyclooxygenase (COX) inhibitors on angiogenesis and cell apoptosis of SKOV-3 human ovarian carcinoma cell xenograft-bearing mice. The experiments were continued for 28 days. Animals were treated with...

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Li W, Tang YX, Wan L, et al. Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts. Oncol Lett. 2012;5(3):923-928doi: 10.3892/ol.2012.1086.
Li, W., Tang, Y. X., Wan, L., Cai, J. H., & Zhang, J. (2013). Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts. Oncology letters, 5(3), 923-928. https://doi.org/10.3892/ol.2012.1086
Li, Wei, et al. "Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts." Oncology letters vol. 5,3 (2013): 923-928. doi: https://doi.org/10.3892/ol.2012.1086
Li W, Tang YX, Wan L, Cai JH, Zhang J. Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts. Oncol Lett. 2013 Mar;5(3):923-928. doi: 10.3892/ol.2012.1086. Epub 2012 Dec 19. PMID: 23426648; PMCID: PMC3576189.
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DPRESS: Localizing estimates of predictive uncertainty.

Journal of cheminformatics

Clark RD.
PMID: 20298517
J Cheminform. 2009 Jul 14;1(1):11. doi: 10.1186/1758-2946-1-11.

BACKGROUND: The need to have a quantitative estimate of the uncertainty of prediction for QSAR models is steadily increasing, in part because such predictions are being widely distributed as tabulated values disconnected from the models used to generate them....

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Clark RD. DPRESS: Localizing estimates of predictive uncertainty. J Cheminform. 2009;1(1):11doi: 10.1186/1758-2946-1-11.
Clark, R. D. (2009). DPRESS: Localizing estimates of predictive uncertainty. Journal of cheminformatics, 1(1), 11. https://doi.org/10.1186/1758-2946-1-11
Clark, Robert D. "DPRESS: Localizing estimates of predictive uncertainty." Journal of cheminformatics vol. 1,1 (2009): 11. doi: https://doi.org/10.1186/1758-2946-1-11
Clark RD. DPRESS: Localizing estimates of predictive uncertainty. J Cheminform. 2009 Jul 14;1(1):11. doi: 10.1186/1758-2946-1-11. PMID: 20298517; PMCID: PMC3225832.
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Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations.

Pharmaceuticals (Basel, Switzerland)

Gáspár R, Hajagos-Tóth J.
PMID: 24276256
Pharmaceuticals (Basel). 2013 May 23;6(6):689-99. doi: 10.3390/ph6060689.

Dihydropyridine Ca2+ channel blockers (CCBs) are widely accepted in the treatment of premature labour. Their mechanism of action in tocolysis involves the blockade of L-type Ca2+ channels, influenced by the Ca2+-activated K+ channels, beta-adrenergic receptors (β-ARs) and sexual hormones....

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Gáspár R, Hajagos-Tóth J. Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel). 2013;6(6):689-99doi: 10.3390/ph6060689.
Gáspár, R., & Hajagos-Tóth, J. (2013). Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel, Switzerland), 6(6), 689-99. https://doi.org/10.3390/ph6060689
Gáspár, Róbert, and Hajagos-Tóth, Judit. "Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations." Pharmaceuticals (Basel, Switzerland) vol. 6,6 (2013): 689-99. doi: https://doi.org/10.3390/ph6060689
Gáspár R, Hajagos-Tóth J. Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel). 2013 May 23;6(6):689-99. doi: 10.3390/ph6060689. PMID: 24276256; PMCID: PMC3816733.
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Effects of cyclooxygenase inhibitors on survival time in ovarian cancer xenograft-bearing mice.

Oncology letters

Li W, Xu XL, Zhang J, Cai JH, Tang YX.
PMID: 23205124
Oncol Lett. 2012 Dec;4(6):1269-1273. doi: 10.3892/ol.2012.929. Epub 2012 Sep 20.

The present study was designed to investigate whether cyclooxygenase (COX) inhibitors (coxibs) could prolong survival time by attenuating the tumor growth of ovarian cancer xenograft-bearing mice. Tumor growth and survival time were observed and compared in mice which were...

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Li W, Xu XL, Zhang J, et al. Effects of cyclooxygenase inhibitors on survival time in ovarian cancer xenograft-bearing mice. Oncol Lett. 2012;4(6):1269-1273doi: 10.3892/ol.2012.929.
Li, W., Xu, X. L., Zhang, J., Cai, J. H., & Tang, Y. X. (2012). Effects of cyclooxygenase inhibitors on survival time in ovarian cancer xenograft-bearing mice. Oncology letters, 4(6), 1269-1273. https://doi.org/10.3892/ol.2012.929
Li, Wei, et al. "Effects of cyclooxygenase inhibitors on survival time in ovarian cancer xenograft-bearing mice." Oncology letters vol. 4,6 (2012): 1269-1273. doi: https://doi.org/10.3892/ol.2012.929
Li W, Xu XL, Zhang J, Cai JH, Tang YX. Effects of cyclooxygenase inhibitors on survival time in ovarian cancer xenograft-bearing mice. Oncol Lett. 2012 Dec;4(6):1269-1273. doi: 10.3892/ol.2012.929. Epub 2012 Sep 20. PMID: 23205124; PMCID: PMC3506753.
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The role of lipids in corneal diseases and dystrophies: a systematic review.

Clinical and translational medicine

Rowsey TG, Karamichos D.
PMID: 28782089
Clin Transl Med. 2017 Dec;6(1):30. doi: 10.1186/s40169-017-0158-1. Epub 2017 Aug 11.

Corneal diseases are an extensive cause of blindness worldwide and continue to persist as a challenging public health concern. Recently, various lipid-based therapies have been advocated for the modulation of corneal diseases; however, the number of studies is still...

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Rowsey TG, Karamichos D. The role of lipids in corneal diseases and dystrophies: a systematic review. Clin Transl Med. 2017;6(1):30doi: 10.1186/s40169-017-0158-1.
Rowsey, T. G., & Karamichos, D. (2017). The role of lipids in corneal diseases and dystrophies: a systematic review. Clinical and translational medicine, 6(1), 30. https://doi.org/10.1186/s40169-017-0158-1
Rowsey, Tyler G, and Karamichos, Dimitrios. "The role of lipids in corneal diseases and dystrophies: a systematic review." Clinical and translational medicine vol. 6,1 (2017): 30. doi: https://doi.org/10.1186/s40169-017-0158-1
Rowsey TG, Karamichos D. The role of lipids in corneal diseases and dystrophies: a systematic review. Clin Transl Med. 2017 Dec;6(1):30. doi: 10.1186/s40169-017-0158-1. Epub 2017 Aug 11. PMID: 28782089; PMCID: PMC5552625.
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Topical diclofenac sodium, dexamethasone and placebo compared in a model of immunogenic uveitis in rabbits.

Ocular immunology and inflammation

Neumann R, Jabbur NS, Vickers F, Foster SC.
PMID: 22827198
Ocul Immunol Inflamm. 1993;1(1):87-98. doi: 10.3109/09273949309086543.

Unacceptable side effects involved in topical steroid usage for uveitis have prompted the search for alternative antiinflammatory drugs for the treatment of ocular inflammation. Cyclooxygenase inhibitors have been widely used for systemic inflammatory conditions over the last two decades...

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Neumann R, Jabbur NS, Vickers F, et al. Topical diclofenac sodium, dexamethasone and placebo compared in a model of immunogenic uveitis in rabbits. Ocul Immunol Inflamm. 1993;1(1):87-98doi: 10.3109/09273949309086543.
Neumann, R., Jabbur, N. S., Vickers, F., & Foster, S. C. (1993). Topical diclofenac sodium, dexamethasone and placebo compared in a model of immunogenic uveitis in rabbits. Ocular immunology and inflammation, 1(1), 87-98. https://doi.org/10.3109/09273949309086543
Neumann, R, et al. "Topical diclofenac sodium, dexamethasone and placebo compared in a model of immunogenic uveitis in rabbits." Ocular immunology and inflammation vol. 1,1 (1993): 87-98. doi: https://doi.org/10.3109/09273949309086543
Neumann R, Jabbur NS, Vickers F, Foster SC. Topical diclofenac sodium, dexamethasone and placebo compared in a model of immunogenic uveitis in rabbits. Ocul Immunol Inflamm. 1993;1(1):87-98. doi: 10.3109/09273949309086543. PMID: 22827198.
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Showing 1 to 12 of 69 entries