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Showing 1 to 7 of 7 entries
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Inhibitory potential of three Yin-tonification herbal formulas on the activities of human major cytochrome P450 and UDP- glucuronosyltransferases isozymes in vitro.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Seong Eun J, Hyeun-Kyoo S, Hyekyung H.
PMID: 32186076
J Tradit Chin Med. 2018 Aug;38(4):511-522.

OBJECTIVE: To investigate the influence of Yin-tonification herbal formulas Jaeumganghwa-tang (Ziyin Jianghuo Tang, JEGHT), Ssanghwa-tang (Shuanghe Tang, SHT) and Yukmijihwang-tang (Liuwei Di huang Tang, YMJHT) on the activities of human major cytochrome P450 (CYP450s) and UDP-glucuronosyltransferases isozymes (UGTs) in...

Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring.

Molecular and cellular pediatrics

Alcorta-García MR, López-Villaseñor CN, Sánchez-Ferrer G, Flores-Mendoza H, Castorena-Torres F, Aguilar-Torres MA, Sepúlveda-Treviño CM, Hernández-Hernández JA, López-Sánchez RC, Lara-Díaz VJ.
PMID: 32476096
Mol Cell Pediatr. 2020 Jun 01;7(1):4. doi: 10.1186/s40348-020-00096-3.

BACKGROUND: To ascertain interactions of caffeine ingestion, food, medications, and environmental exposures during preterm human gestation, under informed consent, we studied a cohort of Mexican women with further preterm offspring born at ≤ 34 completed weeks. At birth, blood...

Anti-platelet Therapy Resistance - Concept, Mechanisms and Platelet Function Tests in Intensive Care Facilities.

Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)

Mărginean A, Bănescu C, Scridon A, Dobreanu M.
PMID: 29967831
J Crit Care Med (Targu Mures). 2016 Feb 09;2(1):6-15. doi: 10.1515/jccm-2015-0021. eCollection 2016 Jan.

It is well known that critically ill patients require special attention and additional consideration during their treatment and management. The multiple systems and organ dysfunctions, typical of the critical patient, often results in different patterns of enteral absorption in...

Xenobiotica; the fate of foreign compounds in biological systems

Säll C, Fogt Hjorth C.
PMID: 34913834
Xenobiotica. 2021 Dec 29;1-15. doi: 10.1080/00498254.2021.2018628. Epub 2021 Dec 29.

1. NDec is a novel, oral, fixed-dose formulation of decitabine and tetrahydrouridine that is currently being developed for the treatment of patients with sickle cell disease. Here, we examine the potential for both components of NDec to interact with...

Association of The Common CYP1A1*2C Variant (Ile462Val Polymorphism) with Chronic Myeloid Leukemia (CML) in Patients Undergoing Imatinib Therapy.

Cell journal

Lakkireddy S, Aula S, Avn S, Kapley A, Rao Digumarti R, Jamil K.
PMID: 26464823
Cell J. 2015;17(3):510-9. doi: 10.22074/cellj.2015.11. Epub 2015 Oct 07.

OBJECTIVE: Cytochrome P450 is one of the major drug metabolizing enzyme families and its role in metabolism of cancer drugs cannot be less emphasized. The association be- tween single nucleotide polymorphisms (SNPs) in CYP1A1 and pathogenesis of chronic myeloid...

Application of a Pharmacogenetics-Based Precision Medicine Model (5SPM) to Psychotic Patients That Presented Poor Response to Neuroleptic Therapy.

Journal of personalized medicine

Carrascal-Laso L, Franco-Martín MÁ, García-Berrocal MB, Marcos-Vadillo E, Sánchez-Iglesias S, Lorenzo C, Sánchez-Martín A, Ramos-Gallego I, García-Salgado MJ, Isidoro-García M, Chu SL, Schlegel R, Quek F, Christy A.
PMID: 33352925
J Pers Med. 2020 Dec 18;10(4). doi: 10.3390/jpm10040289.

Antipsychotics are the keystone of the treatment of severe and prolonged mental disorders. However, there are many risks associated with these drugs and not all patients undergo full therapeutic profit from them. The application of the 5 Step Precision...

Comparison of clinical pharmacology of voriconazole and posaconazole.

Contemporary oncology (Poznan, Poland)

Sienkiewicz BM, Łapiński Ł, Wiela-Hojeńska A.
PMID: 28373817
Contemp Oncol (Pozn). 2016;20(5):365-373. doi: 10.5114/wo.2016.64594. Epub 2016 Dec 20.

Despite greater knowledge and possibilities in pharmacotherapy, fungal infections remain a challenge for clinicians. As the population of immunocompromised patients and those treated for their hematologic ailments increases, the number of fungal infections grows too. This is why there...

Showing 1 to 7 of 7 entries