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Showing 1 to 12 of 16 entries
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Different virulence of .

American journal of translational research

Zhang X, Zhao S, Sun L, Li W, Wei Q, Ashman RB, Hu Y.
PMID: 28123633
Am J Transl Res. 2017 Jan 15;9(1):50-62. eCollection 2017.

No abstract available.

Sex Difference in Plasma Deoxyribonuclease Activity in Rats.

Physiological research

Janovičová Ľ, Gromová B, Drobná D, Konečná B, Renczés E, Borbélyová V, Hodosy J, Celec P.
PMID: 34717068
Physiol Res. 2021 Dec 30;70(6):913-920. doi: 10.33549/physiolres.934766. Epub 2021 Oct 30.

Extracellular DNA (ecDNA) activates immune cells and is involved in the pathogenesis of diseases associated with inflammation such as sepsis, rheumatoid arthritis or metabolic syndrome. DNA can be cleaved by deoxyribonucleases (DNases), some of which are secreted out of...

Deoxyribonuclease I Activity, Cell-Free DNA, and Risk of Liver Cancer in a Prospective Cohort.

JNCI cancer spectrum

Golonka RM, Yeoh BS, Petrick JL, Weinstein SJ, Albanes D, Gewirtz AT, McGlynn KA, Vijay-Kumar M.
PMID: 30815627
JNCI Cancer Spectr. 2018 Dec;2(4):pky083. doi: 10.1093/jncics/pky083. Epub 2019 Feb 21.

BACKGROUND: Circulating cell-free DNA (cfDNA) is a proposed latent biomarker for several cancers, including liver cancer. Deoxyribonucleases (DNases) facilitate the timely and efficient degradation of cfDNA, leading us to hypothesize that DNase I and/or II might be a more...

Possible relationship between yeast deoxyribonucleases and deoxyribonucleic Acid yield.

Applied and environmental microbiology

El-Nakhal H, Phaff HJ.
PMID: 16345800
Appl Environ Microbiol. 1981 Jun;41(6):1482-3. doi: 10.1128/aem.41.6.1482-1483.1981.

The deoxyribonucleic acid (DNA) yield and deoxyribonuclease (DNase) activity of several yeasts were correlated. Debaryomyces castellii and Debaryomyces franciscae were found to contain active DNases which carry out DNA hydrolysis, whereas the amounts of DNA as determined by extraction...

Role of Cell-Free DNA and Deoxyribonucleases in Tumor Progression.

International journal of molecular sciences

Alekseeva L, Mironova N.
PMID: 34830126
Int J Mol Sci. 2021 Nov 12;22(22). doi: 10.3390/ijms222212246.

Many studies have reported an increase in the level of circulating cell-free DNA (cfDNA) in the blood of patients with cancer. cfDNA mainly comes from tumor cells and, therefore, carries features of its genomic profile. Moreover, tumor-derived cfDNA can...

Hyaluronic acid in viscous malignant mesothelioma pleural effusion.

Respirology case reports

Cheah HM, Fitzgerald D, Louw A, Creaney J, Lee YCG.
PMID: 33304592
Respirol Case Rep. 2020 Dec 03;9(1):e00694. doi: 10.1002/rcr2.694. eCollection 2021 Jan.

Malignant pleural effusion (MPE) is common with mesothelioma. We report two cases of extraordinarily viscous MPEs associated with mesothelioma. The viscosity prohibited spontaneous gravity-dependent drainage via indwelling pleural catheters. Our ex vivo experiments found very high hyaluronic acid (HA)...

Sex Difference in Plasma Deoxyribonuclease Activity in Rats.

Physiological research

Janovičová Ľ, Gromová B, Drobná D, Konečná B, Renczés E, Borbélyová V, Hodosy J, Celec P.
PMID: 34717068
Physiol Res. 2021 Oct 30;70(6). Epub 2021 Oct 30.

Extracellular DNA (ecDNA) activates immune cells and is involved in the pathogenesis of diseases associated with inflammation such as sepsis, rheumatoid arthritis or metabolic syndrome. DNA can be cleaved by deoxyribonucleases (DNases), some of which are secreted out of...

Capsular Type, Sequence Type and Microbial Resistance Factors Impact on DNase Activity of .

European journal of microbiology & immunology

Florindo C, Barroco CA, Silvestre I, Damião V, Gomes JP, Spellerberg B, Santos-Sanches I, Borrego MJ.
PMID: 30719332
Eur J Microbiol Immunol (Bp). 2018 Dec 11;8(4):149-154. doi: 10.1556/1886.2018.00026. eCollection 2018 Dec 23.

Extracellular deoxyribonucleases (DNases) contribute to the spread of pathogenic bacteria through the evasion from host innate immunity. Our main objective was to evaluate the production of extracellular DNases by human and bovine

DNase I: structure, function, and use in medicine and forensic science.

Legal medicine (Tokyo, Japan)

Kishi K, Yasuda T, Takeshita H.
PMID: 12935527
Leg Med (Tokyo). 2001 Jun;3(2):69-83. doi: 10.1016/s1344-6223(01)00004-9.

In this review, available structural data of deoxyribonucleases I (DNases I) from several mammalian species, hen, snake and frog are summarized. Comparative studies on enzymatic and immunological properties and glycosylation are discussed, and several evolutionary conclusions are presented. Over...

Characterization of deoxyribonucleases induced by poxviruses.

Journal of virology

Jungwirth C, Launer J, Dombrowski G, Horák I.
PMID: 16789119
J Virol. 1969 Dec;4(6):866-71. doi: 10.1128/JVI.4.6.866-871.1969.

Increases in deoxyribonuclease activity assayed at alkaline pH can be observed in poxvirus-infected cells when native or denatured deoxyribonucleic acid (DNA) is used as substrate. The deoxyribonuclease assayable with native DNA as substrate, induced in HeLa cells by cowpoxvirus...

Extracellular Deoxyribonucleases in Members of the Family Enterobacteriaceae.

Journal of bacteriology

Rothberg NW, Swartz MN.
PMID: 16562039
J Bacteriol. 1965 Jul;90(1):294-5. doi: 10.1128/jb.90.1.294-295.1965.

No abstract available.

Approaches to Dispersing Medical Biofilms.

Microorganisms

Fleming D, Rumbaugh KP.
PMID: 28368320
Microorganisms. 2017 Apr 01;5(2). doi: 10.3390/microorganisms5020015.

Biofilm-associated infections pose a complex problem to the medical community, in that residence within the protection of a biofilm affords pathogens greatly increased tolerances to antibiotics and antimicrobials, as well as protection from the host immune response. This results...

Showing 1 to 12 of 16 entries