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Urine desmosine as a marker of lung injury following total knee arthroplasty. A pilot study.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery

Memtsoudis SG, Starcher B, González Della Valle A, Ma Y, Jules-Elysee K, Sculco TP.
PMID: 19521737
HSS J. 2009 Sep;5(2):154-8. doi: 10.1007/s11420-009-9116-9. Epub 2009 Jun 12.

Lung injury following total knee arthroplasty (TKA) may occur secondary to embolization of bone debris, fat, and cement. Clinically relevant respiratory failure is rare and is therefore difficult to study. To facilitate future investigations on this subject, we evaluated...

Cite
Memtsoudis SG, Starcher B, González Della Valle A, et al. Urine desmosine as a marker of lung injury following total knee arthroplasty. A pilot study. HSS J. 2009;5(2):154-8doi: 10.1007/s11420-009-9116-9.
Memtsoudis, S. G., Starcher, B., González Della Valle, A., Ma, Y., Jules-Elysee, K., & Sculco, T. P. (2009). Urine desmosine as a marker of lung injury following total knee arthroplasty. A pilot study. HSS journal : the musculoskeletal journal of Hospital for Special Surgery, 5(2), 154-8. https://doi.org/10.1007/s11420-009-9116-9
Memtsoudis, Stavros G, et al. "Urine desmosine as a marker of lung injury following total knee arthroplasty. A pilot study." HSS journal : the musculoskeletal journal of Hospital for Special Surgery vol. 5,2 (2009): 154-8. doi: https://doi.org/10.1007/s11420-009-9116-9
Memtsoudis SG, Starcher B, González Della Valle A, Ma Y, Jules-Elysee K, Sculco TP. Urine desmosine as a marker of lung injury following total knee arthroplasty. A pilot study. HSS J. 2009 Sep;5(2):154-8. doi: 10.1007/s11420-009-9116-9. Epub 2009 Jun 12. PMID: 19521737; PMCID: PMC2744754.
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Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;215:108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 215108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. 215 (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
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Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;215:108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 215108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. 215 (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
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Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;215:108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 215108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. 215 (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
Copy Download .nbib Format: NLM
Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;215:108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 215108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. 215 (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
Copy Download .nbib Format: NLM
Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
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Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries.

ERJ open research

Singh KP, Lawyer G, Muthumalage T, Maremanda KP, Khan NA, McDonough SR, Ye D, McIntosh S, Rahman I.
PMID: 31886159
ERJ Open Res. 2019 Dec 23;5(4). doi: 10.1183/23120541.00182-2019. eCollection 2019 Oct.

BACKGROUND: Electronic cigarettes (e-cigs) were introduced as electronic nicotine delivery systems, and have become very popular in the USA and globally. There is a paucity of data on systemic injury biomarkers of vaping in e-cig users that can be...

Cite
Singh KP, Lawyer G, Muthumalage T, et al. Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries. ERJ Open Res. 2019;5(4)doi: 10.1183/23120541.00182-2019.
Singh, K. P., Lawyer, G., Muthumalage, T., Maremanda, K. P., Khan, N. A., McDonough, S. R., Ye, D., McIntosh, S., & Rahman, I. (2019). Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries. ERJ open research, 5(4), . https://doi.org/10.1183/23120541.00182-2019
Singh, Kameshwar P, et al. "Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries." ERJ open research vol. 5,4 (2019). doi: https://doi.org/10.1183/23120541.00182-2019
Singh KP, Lawyer G, Muthumalage T, Maremanda KP, Khan NA, McDonough SR, Ye D, McIntosh S, Rahman I. Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries. ERJ Open Res. 2019 Dec 23;5(4). doi: 10.1183/23120541.00182-2019. eCollection 2019 Oct. PMID: 31886159; PMCID: PMC6926365.
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Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;215:108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 215108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. 215 (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
Copy Download .nbib Format: NLM
Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome.

Experimental eye research

Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N.
PMID: 34929161
Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17.

Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation associated with the disease mechanism is incompletely understood. This study evaluated the molecules of the...

Cite
Rebecca M, Sripriya K, Bharathselvi M, et al. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021;215:108898doi: 10.1016/j.exer.2021.108898.
Rebecca, M., Sripriya, K., Bharathselvi, M., Shantha, B., Vijaya, L., & Angayarkanni, N. (2021). Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Experimental eye research, 215108898. https://doi.org/10.1016/j.exer.2021.108898
Rebecca, Manohar, et al. "Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome." Experimental eye research vol. 215 (2021): 108898. doi: https://doi.org/10.1016/j.exer.2021.108898
Rebecca M, Sripriya K, Bharathselvi M, Shantha B, Vijaya L, Angayarkanni N. Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome. Exp Eye Res. 2021 Dec 17;215:108898. doi: 10.1016/j.exer.2021.108898. Epub 2021 Dec 17. PMID: 34929161.
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A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy.

Respiratory medicine

Cantor JO, Ma S, Liu X, Campos MA, Strange C, Stocks JM, Devine MS, El Bayadi SG, Lipchik RJ, Sandhaus RA, Turino GM.
PMID: 33906126
Respir Med. 2021 Jun;182:106402. doi: 10.1016/j.rmed.2021.106402. Epub 2021 Apr 14.

INTRODUCTION: A previous 2-week clinical trial of aerosolized hyaluronan (HA) in COPD showed a rapid reduction in lung elastic fiber breakdown, as measured by sputum levels of the unique elastin crosslinks, desmosine and isodesmosine (DID). To further assess the...

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Cantor JO, Ma S, Liu X, et al. A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy. Respir Med. 2021;182:106402doi: 10.1016/j.rmed.2021.106402.
Cantor, J. O., Ma, S., Liu, X., Campos, M. A., Strange, C., Stocks, J. M., Devine, M. S., El Bayadi, S. G., Lipchik, R. J., Sandhaus, R. A., & Turino, G. M. (2021). A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy. Respiratory medicine, 182106402. https://doi.org/10.1016/j.rmed.2021.106402
Cantor, Jerome O, et al. "A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy." Respiratory medicine vol. 182 (2021): 106402. doi: https://doi.org/10.1016/j.rmed.2021.106402
Cantor JO, Ma S, Liu X, Campos MA, Strange C, Stocks JM, Devine MS, El Bayadi SG, Lipchik RJ, Sandhaus RA, Turino GM. A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy. Respir Med. 2021 Jun;182:106402. doi: 10.1016/j.rmed.2021.106402. Epub 2021 Apr 14. PMID: 33906126.
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Differences in elastase hydrolysates of elastin from ligamentum nuchae.

FEBS letters

Ledvina M, Bartos F.
PMID: 11945239
FEBS Lett. 1968 Jul;1(1):9-12. doi: 10.1016/0014-5793(68)80005-5.

By means of molecular exclusive chromatography, a marked difference in the distribution of desmosine and isodesmosine in the products of proteolysis has been found between the partial enzymatic hydrolysates of elastin from the bovine nuchal ligament prepared by two...

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Ledvina M, Bartos F. Differences in elastase hydrolysates of elastin from ligamentum nuchae. FEBS Lett. 1968;1(1):9-12doi: 10.1016/0014-5793(68)80005-5.
Ledvina, M., & Bartos, F. (1968). Differences in elastase hydrolysates of elastin from ligamentum nuchae. FEBS letters, 1(1), 9-12. https://doi.org/10.1016/0014-5793(68)80005-5
Ledvina, M, and Bartos, F. "Differences in elastase hydrolysates of elastin from ligamentum nuchae." FEBS letters vol. 1,1 (1968): 9-12. doi: https://doi.org/10.1016/0014-5793(68)80005-5
Ledvina M, Bartos F. Differences in elastase hydrolysates of elastin from ligamentum nuchae. FEBS Lett. 1968 Jul;1(1):9-12. doi: 10.1016/0014-5793(68)80005-5. PMID: 11945239.
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Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease.

Journal of clinical medicine

Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R.
PMID: 31357639
J Clin Med. 2019 Jul 27;8(8). doi: 10.3390/jcm8081116.

Elastin degradation is accelerated in chronic obstructive pulmonary disease (COPD) and is partially regulated by Matrix Gla Protein (MGP), via a vitamin K-dependent pathway. The aim was to assess vitamin K status in COPD as well as associations between...

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Piscaer I, van den Ouweland JMW, Vermeersch K, et al. Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease. J Clin Med. 2019;8(8)doi: 10.3390/jcm8081116.
Piscaer, I., van den Ouweland, J. M. W., Vermeersch, K., Reynaert, N. L., Franssen, F. M. E., Keene, S., Wouters, E. F. M., Janssens, W., Vermeer, C., & Janssen, R. (2019). Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease. Journal of clinical medicine, 8(8), . https://doi.org/10.3390/jcm8081116
Piscaer, Ianthe, et al. "Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease." Journal of clinical medicine vol. 8,8 (2019). doi: https://doi.org/10.3390/jcm8081116
Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R. Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease. J Clin Med. 2019 Jul 27;8(8). doi: 10.3390/jcm8081116. PMID: 31357639; PMCID: PMC6724066.
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