Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 983 entries
Sorted by: Best Match Show Resources per page
Depressant effects of Agastache mexicana methanol extract and one of major metabolites tilianin.

Asian Pacific journal of tropical medicine

González-Trujano ME, Ponce-Muñoz H, Hidalgo-Figueroa S, Navarrete-Vázquez G, Estrada-Soto S.
PMID: 25902158
Asian Pac J Trop Med. 2015 Mar;8(3):185-90. doi: 10.1016/S1995-7645(14)60312-6.

OBJECTIVE: To determine the depressant-like effects and the possible mechanism of action of tilianin isolated from active methanol extract of Agastache mexicana (A. mexicana). Also, to establish the pharmacophoric requirements of tilianin, as a possible ligand of GABAA/BZD receptor,...

Why It Is Not Always Anxiety: A Tough Diagnosis of Stiff Person Syndrome.

Case reports in neurological medicine

Cervantes CE, Lee Lau H, Binazir TA, O'Brien KO, Cross JS.
PMID: 28890837
Case Rep Neurol Med. 2017;2017:7431092. doi: 10.1155/2017/7431092. Epub 2017 Aug 14.

Anxiety disorder is a commonly used diagnosis that may mask underlying conditions. Stiff person syndrome (SPS) is a rare neuroimmunological disorder characterized by progressive rigidity and painful muscle spasms affecting axial and lower extremity musculature. These episodes can be...

Comparison of surgical conditions following premedication with oral clonidine versus oral diazepam for endoscopic sinus surgery: A randomized, double-blinded study.

Journal of anaesthesiology, clinical pharmacology

Bhat Pai RV, Badiger S, Sachidananda R, Basappaji SM, Shanbhag R, Rao R.
PMID: 27275059
J Anaesthesiol Clin Pharmacol. 2016 Apr-Jun;32(2):250-6. doi: 10.4103/0970-9185.182112.

BACKGROUND AND AIMS: Endoscopic sinus surgery (ESS) provides a challenge and an opportunity to the anesthesiologists to prove their mettle and give the surgeons a surgical field which can make their delicate surgery safer,more precise and faster. The aim...

Effect of single-use versus combined-use moschus and diazepam on expression of amino acid neurotransmitters in the rat corpus striatum.

Neural regeneration research

Zhang N, Liu P, He X.
PMID: 25767496
Neural Regen Res. 2012 Jan 25;7(3):182-6. doi: 10.3969/j.issn.1673-5374.2012.03.004.

The present study analyzed expressional changes of excitatory neurotransmitters and inhibitory neurotransmitters in the rat corpus striatum after single-use and combined-use diazepam and Chinese herb moschus. The influence of moschus on the central nervous system was analyzed, in particular...

Hypnotic effect of Coriandrum sativum, Ziziphus jujuba, Lavandula angustifolia and Melissa officinalis extracts in mice.

Research in pharmaceutical sciences

Hajhashemi V, Safaei A.
PMID: 26779267
Res Pharm Sci. 2015 Nov-Dec;10(6):477-84.

The aim of the present study was to evaluate hypnotic effect of Coriandrum sativum, Ziziphus jujuba, Lavandula angustifolia and Melissa officinalis hydroalcoholic extracts in mice to select the most effective ones for a combination formula. Three doses of the...

Therapeutic effect of acupuncture in BALB/c model of cutaneous leishmaniasis.

Advanced biomedical research

Shakibapour M, Mahmoodi M, Hoseini SG, Rostami F, Mansurian M, Jafari R, Izadi S, Charehdar S, Hejazi SH.
PMID: 25879002
Adv Biomed Res. 2015 Mar 25;4:77. doi: 10.4103/2277-9175.153904. eCollection 2015.

BACKGROUND: Current research findings demonstrate that acupuncture, a traditional Chinese medicine, has beneficial effects on several acute and chronic infectious and inflammatory diseases. Acupuncture promotes tissue healing and regulates immune response in various disease conditions. Cutaneous leishmaniasis (CL) is...

Glial Endozepines Inhibit Feeding-Related Autonomic Functions by Acting at the Brainstem Level.

Frontiers in neuroscience

Guillebaud F, Girardet C, Abysique A, Gaigé S, Barbouche R, Verneuil J, Jean A, Leprince J, Tonon MC, Dallaporta M, Lebrun B, Troadec JD.
PMID: 28611581
Front Neurosci. 2017 May 30;11:308. doi: 10.3389/fnins.2017.00308. eCollection 2017.

Endozepines are endogenous ligands for the benzodiazepine receptors and also target a still unidentified GPCR. The endozepine octadecaneuropeptide (ODN), an endoproteolytic processing product of the diazepam-binding inhibitor (DBI) was recently shown to be involved in food intake control as...

Monomeric Octahedral Ruthenium(II) Complex Enabled meta-C-H Nitration of Arenes with Removable Auxiliaries.

Organic letters

Fan Z, Li J, Lu H, Wang DY, Wang C, Uchiyama M, Zhang A.
PMID: 28574271
Org Lett. 2017 Jun 16;19(12):3199-3202. doi: 10.1021/acs.orglett.7b01297. Epub 2017 Jun 02.

A removable oxime-assisted meta-C-H nitration of arenes is reported. Mechanistic investigations and DFT calculations reveal a new monomeric octahedral ruthenium(II) complex is responsible for the meta-selective nitration. Dioxygen as a cooxidant is crucial for achieving high conversion and good...

Berberine attenuates convulsing behavior and extracellular glutamate and aspartate changes in 4-aminopyridine treated rats.

Iranian journal of basic medical sciences

Sadeghnia HR, Taji AR, Forouzanfar F, Hosseinzadeh H.
PMID: 28656093
Iran J Basic Med Sci. 2017 May;20(5):588-593. doi: 10.22038/IJBMS.2017.8756.

OBJECTIVES: K+ channel blocker 4-aminopyridine (4-AP) stimulates the release of glutamate from nerve terminals and induces seizures. Berberine as a potential herbal drug exerts several pharmacological actions on the central nervous system including anxiolytic, anticonvulsant, and neuroprotective properties. The...

Wen-dan decoction improves negative emotions in sleep-deprived rats by regulating orexin-a and leptin expression.

Evidence-based complementary and alternative medicine : eCAM

Wu F, Song Y, Li F, He X, Ma J, Feng T, Guan B, Wang L, Li S, Liu X, Liu Y, Mao M, Liu J, Bai S, Song C.
PMID: 24864160
Evid Based Complement Alternat Med. 2014;2014:872547. doi: 10.1155/2014/872547. Epub 2014 Apr 17.

Wen-Dan Decoction (WDD), a formula of traditional Chinese medicine, has been clinically used for treating insomnia for approximately 800 years. However, the therapeutic mechanisms of WDD remain unclear. Orexin-A plays a key role in the sleep-wake cycle, while leptin...

Effect of diazepam on dopamine and homovanillic acid levels in the corpus striatum of rats pretreated with γ-hydroxybutyric acid.

Neurochemical research

Massotti M.
PMID: 24272327
Neurochem Res. 1977 Dec;2(6):689-94. doi: 10.1007/BF00963781.

The effects of increasing doses of diazepam on striatal dopamine (DA) and homovanillic acid (HVA) levels were studied in rats pretreated with γ-hydroxybutyric acid (GHB). A dose of 750 mg/kg of GHB causes a rise of both DA and...

Anxiolytic, sedative, and hypnotic activities of aqueous extract of Morinda citrifolia fruit.

Journal of Ayurveda and integrative medicine

Kannan S, Manickam S, RajaMohammed MA.
PMID: 24948855
J Ayurveda Integr Med. 2014 Apr;5(2):73-5. doi: 10.4103/0975-9476.131738.

Morinda citrifolia (Indian mulberry or noni) fruit has been long used as a folk medicine for a wide range of health purposes as it is claimed to have analgesic, antiinflammatory, antioxidant, detoxifier, and cell-rejuvenator properties. A recent study has...

Showing 1 to 12 of 983 entries