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Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report.

Journal of medical case reports

Mizrahi A, Czerniak A, Ohana P, Amiur S, Gallula J, Matouk I, Abu-Lail R, Birman T, Hochberg A, Levy T.
PMID: 20663201
J Med Case Rep. 2010 Jul 27;4:228. doi: 10.1186/1752-1947-4-228.

INTRODUCTION: Ovarian cancer ascitic fluid, which contains malignant cells, is usually present in women with an advanced stage disease. There are currently no effective therapies for the treatment of ovarian cancer ascitic fluid. We developed a new therapeutic strategy...

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Mizrahi A, Czerniak A, Ohana P, et al. Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report. J Med Case Rep. 2010;4:228doi: 10.1186/1752-1947-4-228.
Mizrahi, A., Czerniak, A., Ohana, P., Amiur, S., Gallula, J., Matouk, I., Abu-Lail, R., Birman, T., Hochberg, A., & Levy, T. (2010). Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report. Journal of medical case reports, 4228. https://doi.org/10.1186/1752-1947-4-228
Mizrahi, Aya, et al. "Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report." Journal of medical case reports vol. 4 (2010): 228. doi: https://doi.org/10.1186/1752-1947-4-228
Mizrahi A, Czerniak A, Ohana P, Amiur S, Gallula J, Matouk I, Abu-Lail R, Birman T, Hochberg A, Levy T. Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report. J Med Case Rep. 2010 Jul 27;4:228. doi: 10.1186/1752-1947-4-228. PMID: 20663201; PMCID: PMC2918631.
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Optimization of the Expression of DT386-BR2 Fusion Protein in .

Advanced biomedical research

Shafiee F, Rabbani M, Jahanian-Najafabadi A.
PMID: 28349025
Adv Biomed Res. 2017 Mar 01;6:22. doi: 10.4103/2277-9175.201334. eCollection 2017.

BACKGROUND: The aim of this study was to determine the best condition for the production of DT386-BR2 fusion protein, an immunotoxin consisting of catalytic and translocation domains of diphtheria toxin fused to BR2, a cancer specific cell penetrating peptide,...

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Shafiee F, Rabbani M, Jahanian-Najafabadi A. Optimization of the Expression of DT386-BR2 Fusion Protein in . Adv Biomed Res. 2017;6:22doi: 10.4103/2277-9175.201334.
Shafiee, F., Rabbani, M., & Jahanian-Najafabadi, A. (2017). Optimization of the Expression of DT386-BR2 Fusion Protein in . Advanced biomedical research, 622. https://doi.org/10.4103/2277-9175.201334
Shafiee, Fatemeh, et al. "Optimization of the Expression of DT386-BR2 Fusion Protein in ." Advanced biomedical research vol. 6 (2017): 22. doi: https://doi.org/10.4103/2277-9175.201334
Shafiee F, Rabbani M, Jahanian-Najafabadi A. Optimization of the Expression of DT386-BR2 Fusion Protein in . Adv Biomed Res. 2017 Mar 01;6:22. doi: 10.4103/2277-9175.201334. eCollection 2017. PMID: 28349025; PMCID: PMC5353773.
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Global transcriptome analysis of T-competent progenitors in the bone marrow.

Genomics data

Yu VW, Scadden DT.
PMID: 26484235
Genom Data. 2015 Jun 05;5:100-2. doi: 10.1016/j.gdata.2015.05.024. eCollection 2015 Sep.

T cells are known to develop in the thymus. However, molecular events that control the transition from hematopoietic progenitor cells in the bone marrow to T precursor cells seeded in the thymus remained poorly defined. Our recent report showed...

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Yu VW, Scadden DT. Global transcriptome analysis of T-competent progenitors in the bone marrow. Genom Data. 2015;5:100-2doi: 10.1016/j.gdata.2015.05.024.
Yu, V. W., & Scadden, D. T. (2015). Global transcriptome analysis of T-competent progenitors in the bone marrow. Genomics data, 5100-2. https://doi.org/10.1016/j.gdata.2015.05.024
Yu, Vionnie W C, and Scadden, David T. "Global transcriptome analysis of T-competent progenitors in the bone marrow." Genomics data vol. 5 (2015): 100-2. doi: https://doi.org/10.1016/j.gdata.2015.05.024
Yu VW, Scadden DT. Global transcriptome analysis of T-competent progenitors in the bone marrow. Genom Data. 2015 Jun 05;5:100-2. doi: 10.1016/j.gdata.2015.05.024. eCollection 2015 Sep. PMID: 26484235; PMCID: PMC4583637.
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Vaccines Through Centuries: Major Cornerstones of Global Health.

Frontiers in public health

Hajj Hussein I, Chams N, Chams S, El Sayegh S, Badran R, Raad M, Gerges-Geagea A, Leone A, Jurjus A.
PMID: 26636066
Front Public Health. 2015 Nov 26;3:269. doi: 10.3389/fpubh.2015.00269. eCollection 2015.

Multiple cornerstones have shaped the history of vaccines, which may contain live-attenuated viruses, inactivated organisms/viruses, inactivated toxins, or merely segments of the pathogen that could elicit an immune response. The story began with Hippocrates 400 B.C. with his description...

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Hajj Hussein I, Chams N, Chams S, et al. Vaccines Through Centuries: Major Cornerstones of Global Health. Front Public Health. 2015;3:269doi: 10.3389/fpubh.2015.00269.
Hajj Hussein, I., Chams, N., Chams, S., El Sayegh, S., Badran, R., Raad, M., Gerges-Geagea, A., Leone, A., & Jurjus, A. (2015). Vaccines Through Centuries: Major Cornerstones of Global Health. Frontiers in public health, 3269. https://doi.org/10.3389/fpubh.2015.00269
Hajj Hussein, Inaya, et al. "Vaccines Through Centuries: Major Cornerstones of Global Health." Frontiers in public health vol. 3 (2015): 269. doi: https://doi.org/10.3389/fpubh.2015.00269
Hajj Hussein I, Chams N, Chams S, El Sayegh S, Badran R, Raad M, Gerges-Geagea A, Leone A, Jurjus A. Vaccines Through Centuries: Major Cornerstones of Global Health. Front Public Health. 2015 Nov 26;3:269. doi: 10.3389/fpubh.2015.00269. eCollection 2015. PMID: 26636066; PMCID: PMC4659912.
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Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak.

Oncoimmunology

Lutz MB, Baur AS, Schuler-Thurner B, Schuler G.
PMID: 25050193
Oncoimmunology. 2014 Mar 17;3:e28223. doi: 10.4161/onci.28223. eCollection 2014.

Ontak

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Lutz MB, Baur AS, Schuler-Thurner B, et al. Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak. Oncoimmunology. 2014;3:e28223doi: 10.4161/onci.28223.
Lutz, M. B., Baur, A. S., Schuler-Thurner, B., & Schuler, G. (2014). Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak. Oncoimmunology, 3e28223. https://doi.org/10.4161/onci.28223
Lutz, Manfred B, et al. "Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak." Oncoimmunology vol. 3 (2014): e28223. doi: https://doi.org/10.4161/onci.28223
Lutz MB, Baur AS, Schuler-Thurner B, Schuler G. Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak. Oncoimmunology. 2014 Mar 17;3:e28223. doi: 10.4161/onci.28223. eCollection 2014. PMID: 25050193; PMCID: PMC4091105.
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Next generation sequencing analysis of nine Corynebacterium ulcerans isolates reveals zoonotic transmission and a novel putative diphtheria toxin-encoding pathogenicity island.

Genome medicine

Meinel DM, Margos G, Konrad R, Krebs S, Blum H, Sing A.
PMID: 25587356
Genome Med. 2014 Nov 28;6(11):113. doi: 10.1186/s13073-014-0113-3. eCollection 2014.

BACKGROUND: Toxigenic Corynebacterium ulcerans can cause a diphtheria-like illness in humans and have been found in domestic animals, which were suspected to serve as reservoirs for a zoonotic transmission. Additionally, toxigenic C. ulcerans were reported to take over the...

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Meinel DM, Margos G, Konrad R, et al. Next generation sequencing analysis of nine Corynebacterium ulcerans isolates reveals zoonotic transmission and a novel putative diphtheria toxin-encoding pathogenicity island. Genome Med. 2014;6(11):113doi: 10.1186/s13073-014-0113-3.
Meinel, D. M., Margos, G., Konrad, R., Krebs, S., Blum, H., & Sing, A. (2014). Next generation sequencing analysis of nine Corynebacterium ulcerans isolates reveals zoonotic transmission and a novel putative diphtheria toxin-encoding pathogenicity island. Genome medicine, 6(11), 113. https://doi.org/10.1186/s13073-014-0113-3
Meinel, Dominik M, et al. "Next generation sequencing analysis of nine Corynebacterium ulcerans isolates reveals zoonotic transmission and a novel putative diphtheria toxin-encoding pathogenicity island." Genome medicine vol. 6,11 (2014): 113. doi: https://doi.org/10.1186/s13073-014-0113-3
Meinel DM, Margos G, Konrad R, Krebs S, Blum H, Sing A. Next generation sequencing analysis of nine Corynebacterium ulcerans isolates reveals zoonotic transmission and a novel putative diphtheria toxin-encoding pathogenicity island. Genome Med. 2014 Nov 28;6(11):113. doi: 10.1186/s13073-014-0113-3. eCollection 2014. PMID: 25587356; PMCID: PMC4293111.
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Determination of the presence of diphtheria toxin in the myocardial tissue of rabbits and a female subject by using an immunofluorescent antibody method.

Journal of clinical medicine research

Ceyhan M, Ozsurekci Y, Aydin MM, Akcali KC, Talim B, Celik M, Karadag Oncel E, Gurbuz V, Aycan AE, Onbasilar I, Buzgan T.
PMID: 25883712
J Clin Med Res. 2015 Jun;7(6):472-8. doi: 10.14740/jocmr2142w. Epub 2015 Apr 08.

BACKGROUND: Clinical diagnosis of diphtheria is often difficult, in particular in countries where the disease is rarely observed, such as Turkey. In 2011, after 12 years of no recorded diphtheria cases in Turkey, a 34-year-old woman was diagnosed with...

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Ceyhan M, Ozsurekci Y, Aydin MM, et al. Determination of the presence of diphtheria toxin in the myocardial tissue of rabbits and a female subject by using an immunofluorescent antibody method. J Clin Med Res. 2015;7(6):472-8doi: 10.14740/jocmr2142w.
Ceyhan, M., Ozsurekci, Y., Aydin, M. M., Akcali, K. C., Talim, B., Celik, M., Karadag Oncel, E., Gurbuz, V., Aycan, A. E., Onbasilar, I., & Buzgan, T. (2015). Determination of the presence of diphtheria toxin in the myocardial tissue of rabbits and a female subject by using an immunofluorescent antibody method. Journal of clinical medicine research, 7(6), 472-8. https://doi.org/10.14740/jocmr2142w
Ceyhan, Mehmet, et al. "Determination of the presence of diphtheria toxin in the myocardial tissue of rabbits and a female subject by using an immunofluorescent antibody method." Journal of clinical medicine research vol. 7,6 (2015): 472-8. doi: https://doi.org/10.14740/jocmr2142w
Ceyhan M, Ozsurekci Y, Aydin MM, Akcali KC, Talim B, Celik M, Karadag Oncel E, Gurbuz V, Aycan AE, Onbasilar I, Buzgan T. Determination of the presence of diphtheria toxin in the myocardial tissue of rabbits and a female subject by using an immunofluorescent antibody method. J Clin Med Res. 2015 Jun;7(6):472-8. doi: 10.14740/jocmr2142w. Epub 2015 Apr 08. PMID: 25883712; PMCID: PMC4394922.
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Gene therapy for human colorectal carcinoma using human CEA promoter contro led bacterial ADP-ribosylating toxin genes human CEA: PEA & DTA gene transfer.

World journal of gastroenterology

Cao GW, Qi ZT, Pan X, Zhang XQ, Miao XH, Feng Y, Lu XH, Kuriyama S, Du P.
PMID: 11819328
World J Gastroenterol. 1998 Oct;4(5):388-391. doi: 10.3748/wjg.v4.i5.388.

AIM:To establish a tissue-specific gene therapy for colorectal carcinoma using bacterial ADP-ribosylating toxin genes. METHODS:Pseudomonas exotoxin A domain [II+III (PEA) was cloned from genomic DNA of Pseudomonas aeruginosa.PEA and diphtheria toxin A chain gene (DTA) were modified to express...

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Cao GW, Qi ZT, Pan X, et al. Gene therapy for human colorectal carcinoma using human CEA promoter contro led bacterial ADP-ribosylating toxin genes human CEA: PEA & DTA gene transfer. World J Gastroenterol. 1998;4(5):388-391doi: 10.3748/wjg.v4.i5.388.
Cao, G. W., Qi, Z. T., Pan, X., Zhang, X. Q., Miao, X. H., Feng, Y., Lu, X. H., Kuriyama, S., & Du, P. (1998). Gene therapy for human colorectal carcinoma using human CEA promoter contro led bacterial ADP-ribosylating toxin genes human CEA: PEA & DTA gene transfer. World journal of gastroenterology, 4(5), 388-391. https://doi.org/10.3748/wjg.v4.i5.388
Cao, Guang-Wen, et al. "Gene therapy for human colorectal carcinoma using human CEA promoter contro led bacterial ADP-ribosylating toxin genes human CEA: PEA & DTA gene transfer." World journal of gastroenterology vol. 4,5 (1998): 388-391. doi: https://doi.org/10.3748/wjg.v4.i5.388
Cao GW, Qi ZT, Pan X, Zhang XQ, Miao XH, Feng Y, Lu XH, Kuriyama S, Du P. Gene therapy for human colorectal carcinoma using human CEA promoter contro led bacterial ADP-ribosylating toxin genes human CEA: PEA & DTA gene transfer. World J Gastroenterol. 1998 Oct;4(5):388-391. doi: 10.3748/wjg.v4.i5.388. PMID: 11819328; PMCID: PMC4767734.
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Genetic Ablation of Floral Cells in Arabidopsis.

The Plant cell

Thorsness MK, Kandasamy MK, Nasrallah ME, Nasrallah JB.
PMID: 12271062
Plant Cell. 1993 Mar;5(3):253-261. doi: 10.1105/tpc.5.3.253.

A chimeric toxic gene consisting of the diphtheria toxin A chain gene fused to a promoter previously shown to direct pistil- and anther-specific expression was used to genetically target cell killing in transgenic Arabidopsis. Flowers of Arabidopsis transformants that...

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Thorsness MK, Kandasamy MK, Nasrallah ME, et al. Genetic Ablation of Floral Cells in Arabidopsis. Plant Cell. 1993;5(3):253-261doi: 10.1105/tpc.5.3.253.
Thorsness, M. K., Kandasamy, M. K., Nasrallah, M. E., & Nasrallah, J. B. (1993). Genetic Ablation of Floral Cells in Arabidopsis. The Plant cell, 5(3), 253-261. https://doi.org/10.1105/tpc.5.3.253
Thorsness, M. K., et al. "Genetic Ablation of Floral Cells in Arabidopsis." The Plant cell vol. 5,3 (1993): 253-261. doi: https://doi.org/10.1105/tpc.5.3.253
Thorsness MK, Kandasamy MK, Nasrallah ME, Nasrallah JB. Genetic Ablation of Floral Cells in Arabidopsis. Plant Cell. 1993 Mar;5(3):253-261. doi: 10.1105/tpc.5.3.253. PMID: 12271062; PMCID: PMC160267.
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AN EFFECT OF SHORT ELECTRIC WAVES ON DIPHTHERIA TOXIN INDEPENDENT OF THE HEAT FACTOR.

Science (New York, N.Y.)

Mellon RR, Szymanowski WT, Hicks RA.
PMID: 17811682
Science. 1930 Aug 15;72(1859):174-5. doi: 10.1126/science.72.1859.174-a.

No abstract available.

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Mellon RR, Szymanowski WT, Hicks RA. AN EFFECT OF SHORT ELECTRIC WAVES ON DIPHTHERIA TOXIN INDEPENDENT OF THE HEAT FACTOR. Science. 1930;72(1859):174-5doi: 10.1126/science.72.1859.174-a.
Mellon, R. R., Szymanowski, W. T., & Hicks, R. A. (1930). AN EFFECT OF SHORT ELECTRIC WAVES ON DIPHTHERIA TOXIN INDEPENDENT OF THE HEAT FACTOR. Science (New York, N.Y.), 72(1859), 174-5. https://doi.org/10.1126/science.72.1859.174-a
Mellon, R R, et al. "AN EFFECT OF SHORT ELECTRIC WAVES ON DIPHTHERIA TOXIN INDEPENDENT OF THE HEAT FACTOR." Science (New York, N.Y.) vol. 72,1859 (1930): 174-5. doi: https://doi.org/10.1126/science.72.1859.174-a
Mellon RR, Szymanowski WT, Hicks RA. AN EFFECT OF SHORT ELECTRIC WAVES ON DIPHTHERIA TOXIN INDEPENDENT OF THE HEAT FACTOR. Science. 1930 Aug 15;72(1859):174-5. doi: 10.1126/science.72.1859.174-a. PMID: 17811682.
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STUDIES ON CARBON DIOXIDE V. THE MECHANISM RESPONSIBLE FOR THE PRESERVING ACTION OF CARBON DIOXIDE ON DIPHTHERIA TOXIN.

Journal of bacteriology

Plastridge WN, Rettger LF.
PMID: 16559382
J Bacteriol. 1929 Aug;18(2):101-15. doi: 10.1128/jb.18.2.101-115.1929.

No abstract available.

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Plastridge WN, Rettger LF. STUDIES ON CARBON DIOXIDE V. THE MECHANISM RESPONSIBLE FOR THE PRESERVING ACTION OF CARBON DIOXIDE ON DIPHTHERIA TOXIN. J Bacteriol. 1929;18(2):101-15doi: 10.1128/jb.18.2.101-115.1929.
Plastridge, W. N., & Rettger, L. F. (1929). STUDIES ON CARBON DIOXIDE V. THE MECHANISM RESPONSIBLE FOR THE PRESERVING ACTION OF CARBON DIOXIDE ON DIPHTHERIA TOXIN. Journal of bacteriology, 18(2), 101-15. https://doi.org/10.1128/jb.18.2.101-115.1929
Plastridge, W N, and Rettger, L F. "STUDIES ON CARBON DIOXIDE V. THE MECHANISM RESPONSIBLE FOR THE PRESERVING ACTION OF CARBON DIOXIDE ON DIPHTHERIA TOXIN." Journal of bacteriology vol. 18,2 (1929): 101-15. doi: https://doi.org/10.1128/jb.18.2.101-115.1929
Plastridge WN, Rettger LF. STUDIES ON CARBON DIOXIDE V. THE MECHANISM RESPONSIBLE FOR THE PRESERVING ACTION OF CARBON DIOXIDE ON DIPHTHERIA TOXIN. J Bacteriol. 1929 Aug;18(2):101-15. doi: 10.1128/jb.18.2.101-115.1929. PMID: 16559382; PMCID: PMC375071.
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Further Studies upon the Effect of Various Carbohydrates on Production of Diphtheria Toxin with Special Reference to its Flocculating Titer and Final pH.

Journal of bacteriology

Hazen EL, Heller G.
PMID: 16559546
J Bacteriol. 1932 Mar;23(3):195-209. doi: 10.1128/jb.23.3.195-209.1932.

No abstract available.

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Hazen EL, Heller G. Further Studies upon the Effect of Various Carbohydrates on Production of Diphtheria Toxin with Special Reference to its Flocculating Titer and Final pH. J Bacteriol. 1932;23(3):195-209doi: 10.1128/jb.23.3.195-209.1932.
Hazen, E. L., & Heller, G. (1932). Further Studies upon the Effect of Various Carbohydrates on Production of Diphtheria Toxin with Special Reference to its Flocculating Titer and Final pH. Journal of bacteriology, 23(3), 195-209. https://doi.org/10.1128/jb.23.3.195-209.1932
Hazen, E L, and Heller, G. "Further Studies upon the Effect of Various Carbohydrates on Production of Diphtheria Toxin with Special Reference to its Flocculating Titer and Final pH." Journal of bacteriology vol. 23,3 (1932): 195-209. doi: https://doi.org/10.1128/jb.23.3.195-209.1932
Hazen EL, Heller G. Further Studies upon the Effect of Various Carbohydrates on Production of Diphtheria Toxin with Special Reference to its Flocculating Titer and Final pH. J Bacteriol. 1932 Mar;23(3):195-209. doi: 10.1128/jb.23.3.195-209.1932. PMID: 16559546; PMCID: PMC533316.
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Showing 1 to 12 of 290 entries