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Showing 1 to 12 of 93 entries
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GM-CSF as successful salvage therapy of metamizole (dipyrone)-induced agranulocytosis with Fournier's gangrene and severe septic shock in an adolescent.

Clinical case reports

Winkler A, Kietz S, Bahlmann H, Jafarzade G, Lode HN, Heckmann M.
PMID: 27525093
Clin Case Rep. 2016 Jul 20;4(8):816-9. doi: 10.1002/ccr3.616. eCollection 2016 Aug.

This case report describes the successful use of granulocyte and macrophage colony-stimulating factor as salvage therapy and an alternative to hematopoietic stem cell transplantation in a 14-year-old adolescent with metamizole (dipyrone)-induced agranulocytosis and severe septic shock.

Antinociceptive effect of aqueous extracts from the bark of Croton guatemalensis Lotsy in mice.

Research in pharmaceutical sciences

Del Carmen RO, Willam HM, Del Carmen GM, Nataly JG, Stefany CO, Anahi CA, Domingo PT, Leonardo GP, Miguel Pde L.
PMID: 27051428
Res Pharm Sci. 2016 Jan-Feb;11(1):15-22.

Croton guatemalensis Lotsy (CGL), known as "copalchi" in Chiapas, Mexico, is used for the treatment of fever, abdominal pain and malaria and also as a remedy for chills and for treating rheumatism. The aim of this study was to...

Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells.

Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

Shao J, Feng G.
PMID: 24385693
Chin J Cancer Res. 2013 Dec;25(6):662-70. doi: 10.3978/j.issn.1000-9604.2013.11.05.

OBJECTIVE: To determine the selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells.METHODS: Proliferation assay, lactate dehydrogenase (LDH) assay, apoptosis detecting, flow cytometry and western blot were performed.RESULTS: It was found that treatment with propafenone...

Clinical Comparison of Dexketoprofen Trometamol and Dipyrone in Postoperative Dental Pain.

Journal of clinical pharmacology

Bagán JV, López Arranz JS, Valencia E, Santamaría J, Eguidazu I, Horas M, Forns M, Zapata A, Artigas R, Mauleón D.
PMID: 29023870
J Clin Pharmacol. 1998 Dec;38:55S-64S. doi: 10.1002/jcph.1998.38.s1.55.

A total of 125 outpatients with moderate to severe pain after surgical removal of one impacted third molar were randomly assigned to receive dexketoprofen trometamol 12.5 or 25 mg or dipyrone 575 mg. For first-dose assessments, patients rated their...

[Current conservative treatment of renal colic: value of prostaglandin synthesis inhibitors].

Schmerz (Berlin, Germany)

Zwergel U, Felgner J, Rombach H, Zwergel T.
PMID: 12799978
Schmerz. 1998 Apr 20;12(2):112-7. doi: 10.1007/s004829800049.

Prostaglandin synthesis inhibitors and parasympatholytic drugs are often used as analgetics in the case of renal colic. This paper analyzes how and whether these drug effects are important for the analgetic therapy. In an animal and in a human...

[Analgesic and analgesia-potentiating action of B vitamins].

Schmerz (Berlin, Germany)

Jurna I.
PMID: 12799982
Schmerz. 1998 Apr 20;12(2):136-41. doi: 10.1007/s004829800054.

Disregarding pain resulting from vitamin deficiency, an analgesic effect seems to be exerted only by vitamin B1 (thiamine), vitamin B6 (pyridoxines), and vitamin B12 (cobalamine), particularly when the three are given in combination. The analgesic effect is attributed to...

Synthesis and Analgesic Activity of eta-(Anisole)- Triscarbonyl-Chromium(0).

Metal-based drugs

Andrade E Silva ML, Neto AF, Miller J.
PMID: 18475877
Met Based Drugs. 1999;6(1):25-9. doi: 10.1155/MBD.1999.25.

The general method for synthesis the eta(6)-(arene)-triscarbonyl-chromium(0) complexes was modified and applied for preparation of eta(6)-(anisole)-triscarbonyl-chromium(0) and the study of its analgesic activity was undertaken. A significant analgesic activity was observed after intraperitoneal injection, in Wistar rats. Two doses...

Diffusion layer titration of dipyrone in pharmaceuticals at a dual-band electrochemical cell.

Talanta

Paixão TR, Camargo Matos R, Bertotti M.
PMID: 18969237
Talanta. 2003 Dec 04;61(5):725-32. doi: 10.1016/S0039-9140(03)00334-5.

This paper describes the use of a thin-layered dual-band electrochemical cell operating at flow conditions to determine dipyrone (sodium salt of 1-phenil-2,3-dimethyl-4-methylaminomethanesulfonate-5-pyrazolone) by reaction with electrogenerated iodine. The electrolytic cell consisted of two closely spaced gold electrodes, the upper...

Intramuscular Dipyrone versus Oral Ibuprofen or Nimesulide for Reduction of Fever in the Outpatient Setting.

Clinical drug investigation

Yilmaz HL, Alparslan N, Yildizdas D, Bayram I, Alhan E.
PMID: 17535064
Clin Drug Investig. 2003;23(8):519-26. doi: 10.2165/00044011-200323080-00004.

OBJECTIVE: To compare the effectiveness and rate of temperature reduction of three antipyretic medications in febrile children.DESIGN: A single-dose, randomised, prospective, modified double-blind, parallel clinical trial.SETTING: The paediatric emergency department of a university hospital that has 13 000 annual...

Electronic micropipettor: a versatile fluid propulsion and injection device for micro-flow analysis.

Analytica chimica acta

Daniel D, Gutz IG.
PMID: 17723442
Anal Chim Acta. 2006 Jul 07;571(2):218-27. doi: 10.1016/j.aca.2006.04.076. Epub 2006 May 05.

The shortage of ready to use small sized liquid propulsion and switching devices for microfluidic cells (micro-cell) is a bottleneck in the dissemination of micro-flow analysis (mu-FA), now that microfluidic electrochemical cells can be designed and assembled in any...

Comparison of dexketoprofen trometamol and dipyrone in the treatment of renal colic.

Clinical drug investigation

Sánchez-Carpena J, Sesma-Sánchez J, Sánchez-Juan C, Tomás-Vecina S, García-Alonso D, Rico-Salvadó J, Forns M, Mas M, Paredes I, Artigas R.
PMID: 23340921
Clin Drug Investig. 2003;23(3):139-52. doi: 10.2165/00044011-200323030-00001.

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used for pain relief in patients with renal colic. Dexketoprofen trometamol is an NSAID that has demonstrated good analgesic efficacy and a good safety profile after oral administration in different models...

Anesthetic management for oocyte retrieval: An exploratory analysis comparing outcome in in vitro fertilization cycles with and without pre-implantation genetic diagnosis.

Journal of human reproductive sciences

Ioscovich A, Eldar-Geva T, Weitman M, Altarescu G, Rivilis A, Elstein D.
PMID: 24672167
J Hum Reprod Sci. 2013 Oct;6(4):263-6. doi: 10.4103/0974-1208.126303.

PURPOSE: To date, there has been no comparison of outcomes in women undergoing anesthesia for in vitro fertilization (IVF) oocyte retrieval for the purpose of pre-implantation genetic diagnosis (PGD) because of their or their partner's genetic disease relative to...

Showing 1 to 12 of 93 entries