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Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D(1) dopamine antagonists SCH-39166 and A-66359.

Behavioural pharmacology

Vanover KE, Kleven MS, Woolverton WL.
PMID: 11224059
Behav Pharmacol. 1991 Apr;2(2):151-159.

Rhesus monkeys were trained in a 2-lever, food-reinforced drug discrimination paradigm to discriminate cocaine (0.2 or 0.4mg/kg, i.m., 10min pre-session) from saline. Before test sessions, in which responding on either lever was reinforced, the monkeys were injected with various...

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Vanover KE, Kleven MS, Woolverton WL. Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D(1) dopamine antagonists SCH-39166 and A-66359. Behav Pharmacol. 1991;2(2):151-159
Vanover, K. E., Kleven, M. S., & Woolverton, W. L. (1991). Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D(1) dopamine antagonists SCH-39166 and A-66359. Behavioural pharmacology, 2(2), 151-159.
Vanover, K.E., et al. "Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D(1) dopamine antagonists SCH-39166 and A-66359." Behavioural pharmacology vol. 2,2 (1991): 151-159.
Vanover KE, Kleven MS, Woolverton WL. Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D(1) dopamine antagonists SCH-39166 and A-66359. Behav Pharmacol. 1991 Apr;2(2):151-159. PMID: 11224059.
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Time-dependent and schedule-dependent effects of dopamine receptor blockade.

Behavioural pharmacology

Willner P, Phillips G, Sampson D, Muscat R.
PMID: 11175400
Behav Pharmacol. 1989;1(2):169-176.

Rats were trained on one of two multiple random-interval schedules of reinforcement, which contained both ascending and descending reinforcement density sequences. The design of the schedules made it possible to determine whether performance changes in a particular component depended...

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Willner P, Phillips G, Sampson D, et al. Time-dependent and schedule-dependent effects of dopamine receptor blockade. Behav Pharmacol. 1989;1(2):169-176
Willner, P., Phillips, G., Sampson, D., & Muscat, R. (1989). Time-dependent and schedule-dependent effects of dopamine receptor blockade. Behavioural pharmacology, 1(2), 169-176.
Willner, P., et al. "Time-dependent and schedule-dependent effects of dopamine receptor blockade." Behavioural pharmacology vol. 1,2 (1989): 169-176.
Willner P, Phillips G, Sampson D, Muscat R. Time-dependent and schedule-dependent effects of dopamine receptor blockade. Behav Pharmacol. 1989;1(2):169-176. PMID: 11175400.
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Tetrabenazine is neuroprotective in Huntington's disease mice.

Molecular neurodegeneration

Wang H, Chen X, Li Y, Tang TS, Bezprozvanny I.
PMID: 20420689
Mol Neurodegener. 2010 Apr 26;5:18. doi: 10.1186/1750-1326-5-18.

BACKGROUND: Huntington's disease (HD) is a neurodegenerative disorder caused by a polyglutamine (polyQ) expansion in Huntingtin protein (Htt). PolyQ expansion in Httexp causes selective degeneration of striatal medium spiny neurons (MSN) in HD patients. A number of previous studies...

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Wang H, Chen X, Li Y, et al. Tetrabenazine is neuroprotective in Huntington's disease mice. Mol Neurodegener. 2010;5:18doi: 10.1186/1750-1326-5-18.
Wang, H., Chen, X., Li, Y., Tang, T. S., & Bezprozvanny, I. (2010). Tetrabenazine is neuroprotective in Huntington's disease mice. Molecular neurodegeneration, 518. https://doi.org/10.1186/1750-1326-5-18
Wang, Hongyu, et al. "Tetrabenazine is neuroprotective in Huntington's disease mice." Molecular neurodegeneration vol. 5 (2010): 18. doi: https://doi.org/10.1186/1750-1326-5-18
Wang H, Chen X, Li Y, Tang TS, Bezprozvanny I. Tetrabenazine is neuroprotective in Huntington's disease mice. Mol Neurodegener. 2010 Apr 26;5:18. doi: 10.1186/1750-1326-5-18. PMID: 20420689; PMCID: PMC2873255.
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Potentiation of licking in rats by stimulation of both D-1 and D-2 dopamine receptors.

Journal of psychopharmacology (Oxford, England)

Zarrindast MR, Roushan-Zamir F, Amir-Rahmat F, Moslehi M.
PMID: 22291386
J Psychopharmacol. 1992 Jan;6(3):395-8. doi: 10.1177/026988119200600309.

Apomorphine-induced licking in rats was assessed by recording the total number of licks by direct observation. Apomorphine induced licking dose dependently. The maximum response was obtained by 0.5 mg/kg of the drug and 30 min after drug administration. Pre-treatment...

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Zarrindast MR, Roushan-Zamir F, Amir-Rahmat F, et al. Potentiation of licking in rats by stimulation of both D-1 and D-2 dopamine receptors. J Psychopharmacol. 1992;6(3):395-8doi: 10.1177/026988119200600309.
Zarrindast, M. R., Roushan-Zamir, F., Amir-Rahmat, F., & Moslehi, M. (1992). Potentiation of licking in rats by stimulation of both D-1 and D-2 dopamine receptors. Journal of psychopharmacology (Oxford, England), 6(3), 395-8. https://doi.org/10.1177/026988119200600309
Zarrindast, M R, et al. "Potentiation of licking in rats by stimulation of both D-1 and D-2 dopamine receptors." Journal of psychopharmacology (Oxford, England) vol. 6,3 (1992): 395-8. doi: https://doi.org/10.1177/026988119200600309
Zarrindast MR, Roushan-Zamir F, Amir-Rahmat F, Moslehi M. Potentiation of licking in rats by stimulation of both D-1 and D-2 dopamine receptors. J Psychopharmacol. 1992 Jan;6(3):395-8. doi: 10.1177/026988119200600309. PMID: 22291386.
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The role of neurokinin-1 (substance P) antagonists in the prevention of postoperative nausea and vomiting.

Journal of anaesthesiology, clinical pharmacology

Okafor D, Kaye AD, Kaye RJ, Urman RD.
PMID: 29416232
J Anaesthesiol Clin Pharmacol. 2017 Oct-Dec;33(4):441-445. doi: 10.4103/0970-9185.222511.

Postoperative nausea and vomiting (PONV) can be very debilitating for surgical patients, and effective management reduces potential morbidity, aiding in patient satisfaction, and minimizing the need for unintended hospital stays. Risk factors include female sex, nonsmoker, and having a...

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Okafor D, Kaye AD, Kaye RJ, et al. The role of neurokinin-1 (substance P) antagonists in the prevention of postoperative nausea and vomiting. J Anaesthesiol Clin Pharmacol. 2017;33(4):441-445doi: 10.4103/0970-9185.222511.
Okafor, D., Kaye, A. D., Kaye, R. J., & Urman, R. D. (2017). The role of neurokinin-1 (substance P) antagonists in the prevention of postoperative nausea and vomiting. Journal of anaesthesiology, clinical pharmacology, 33(4), 441-445. https://doi.org/10.4103/0970-9185.222511
Okafor, Dionne, et al. "The role of neurokinin-1 (substance P) antagonists in the prevention of postoperative nausea and vomiting." Journal of anaesthesiology, clinical pharmacology vol. 33,4 (2017): 441-445. doi: https://doi.org/10.4103/0970-9185.222511
Okafor D, Kaye AD, Kaye RJ, Urman RD. The role of neurokinin-1 (substance P) antagonists in the prevention of postoperative nausea and vomiting. J Anaesthesiol Clin Pharmacol. 2017 Oct-Dec;33(4):441-445. doi: 10.4103/0970-9185.222511. PMID: 29416232; PMCID: PMC5791253.
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The Effect of Dopamine Antagonist Treatment on Auditory Verbal Hallucinations in Healthy Individuals Is Clearly Influenced by .

Frontiers in genetics

Zhuo C, Xu Y, Zhang L, Jing R, Zhou C.
PMID: 30894870
Front Genet. 2019 Mar 06;10:92. doi: 10.3389/fgene.2019.00092. eCollection 2019.

Few studies have been conducted to explore the influence of the catechol-o-methyltransferase (

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Zhuo C, Xu Y, Zhang L, et al. The Effect of Dopamine Antagonist Treatment on Auditory Verbal Hallucinations in Healthy Individuals Is Clearly Influenced by . Front Genet. 2019;10:92doi: 10.3389/fgene.2019.00092.
Zhuo, C., Xu, Y., Zhang, L., Jing, R., & Zhou, C. (2019). The Effect of Dopamine Antagonist Treatment on Auditory Verbal Hallucinations in Healthy Individuals Is Clearly Influenced by . Frontiers in genetics, 1092. https://doi.org/10.3389/fgene.2019.00092
Zhuo, Chuanjun, et al. "The Effect of Dopamine Antagonist Treatment on Auditory Verbal Hallucinations in Healthy Individuals Is Clearly Influenced by ." Frontiers in genetics vol. 10 (2019): 92. doi: https://doi.org/10.3389/fgene.2019.00092
Zhuo C, Xu Y, Zhang L, Jing R, Zhou C. The Effect of Dopamine Antagonist Treatment on Auditory Verbal Hallucinations in Healthy Individuals Is Clearly Influenced by . Front Genet. 2019 Mar 06;10:92. doi: 10.3389/fgene.2019.00092. eCollection 2019. PMID: 30894870; PMCID: PMC6414462.
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Activation of D1/5 Dopamine Receptors in the Dorsal Medial Prefrontal Cortex Promotes Incubated-Like Aversive Responses.

Frontiers in behavioral neuroscience

Castillo Díaz F, Kramar CP, Hernandez MA, Medina JH.
PMID: 29163081
Front Behav Neurosci. 2017 Oct 31;11:209. doi: 10.3389/fnbeh.2017.00209. eCollection 2017.

It is well established that neurons of the mammalian medial prefrontal cortex (mPFC) modulate different behavioral outputs, including several memory types. This behavioral modulation is, at least in part, under the control of the D1-like Dopamine (DA) receptor (D1/5R)...

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Castillo Díaz F, Kramar CP, Hernandez MA, et al. Activation of D1/5 Dopamine Receptors in the Dorsal Medial Prefrontal Cortex Promotes Incubated-Like Aversive Responses. Front Behav Neurosci. 2017;11:209doi: 10.3389/fnbeh.2017.00209.
Castillo Díaz, F., Kramar, C. P., Hernandez, M. A., & Medina, J. H. (2017). Activation of D1/5 Dopamine Receptors in the Dorsal Medial Prefrontal Cortex Promotes Incubated-Like Aversive Responses. Frontiers in behavioral neuroscience, 11209. https://doi.org/10.3389/fnbeh.2017.00209
Castillo Díaz, Fernando, et al. "Activation of D1/5 Dopamine Receptors in the Dorsal Medial Prefrontal Cortex Promotes Incubated-Like Aversive Responses." Frontiers in behavioral neuroscience vol. 11 (2017): 209. doi: https://doi.org/10.3389/fnbeh.2017.00209
Castillo Díaz F, Kramar CP, Hernandez MA, Medina JH. Activation of D1/5 Dopamine Receptors in the Dorsal Medial Prefrontal Cortex Promotes Incubated-Like Aversive Responses. Front Behav Neurosci. 2017 Oct 31;11:209. doi: 10.3389/fnbeh.2017.00209. eCollection 2017. PMID: 29163081; PMCID: PMC5674926.
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Gabapentin treatment in clozapine-induced restless legs syndrome: two cases and a review of the literature.

Therapeutic advances in psychopharmacology

Kumar V, Venkatasubramanian G.
PMID: 28101323
Ther Adv Psychopharmacol. 2017 Jan;7(1):42-47. doi: 10.1177/2045125316672133. Epub 2016 Oct 12.

Restless legs syndrome (RLS) is a neuro-sensorimotor disorder affecting 2-4% of adults. It is characterized by intense urges to move the legs, associated with unpleasant sensory disturbances in the legs occurring at rest and manifests mostly in the evening...

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Kumar V, Venkatasubramanian G. Gabapentin treatment in clozapine-induced restless legs syndrome: two cases and a review of the literature. Ther Adv Psychopharmacol. 2016;7(1):42-47doi: 10.1177/2045125316672133.
Kumar, V., & Venkatasubramanian, G. (2017). Gabapentin treatment in clozapine-induced restless legs syndrome: two cases and a review of the literature. Therapeutic advances in psychopharmacology, 7(1), 42-47. https://doi.org/10.1177/2045125316672133
Kumar, Vijaya, and Venkatasubramanian, Ganesan. "Gabapentin treatment in clozapine-induced restless legs syndrome: two cases and a review of the literature." Therapeutic advances in psychopharmacology vol. 7,1 (2017): 42-47. doi: https://doi.org/10.1177/2045125316672133
Kumar V, Venkatasubramanian G. Gabapentin treatment in clozapine-induced restless legs syndrome: two cases and a review of the literature. Ther Adv Psychopharmacol. 2017 Jan;7(1):42-47. doi: 10.1177/2045125316672133. Epub 2016 Oct 12. PMID: 28101323; PMCID: PMC5228712.
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A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Orsini A, Foiadelli T, Magistrali M, Carli N, Bagnasco I, Dassi P, Verrotti A, Marcotulli D, Canavese C, Nicita F, Capuano A, Marra C, Fetta A, Nosadini M, Sartori S, Papa A, Viri M, Greco F, Pavone P, Simonini G, Matricardi S, Siquilini S, Marchese F, De Grandis E, Brunenghi BM, Malattia C, Bassanese F, Bergonzini P, Bonuccelli A, Consolini R, Marseglia GL, Peroni D, Striano P, Cordelli D, Savasta S.
PMID: 34768201
Eur J Paediatr Neurol. 2021 Nov 06;36:1-6. doi: 10.1016/j.ejpn.2021.11.002. Epub 2021 Nov 06.

OBJECTIVES: Sydenham's Chorea (SC) is a neuropsychiatric disorder and a major manifestation of acute rheumatic fever. The erroneous assumption that SC is a benign and self-limiting disease, has led to a lack of high-quality scientific evidence of the therapeutical...

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Orsini A, Foiadelli T, Magistrali M, et al. A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors. Eur J Paediatr Neurol. 2021;36:1-6doi: 10.1016/j.ejpn.2021.11.002.
Orsini, A., Foiadelli, T., Magistrali, M., Carli, N., Bagnasco, I., Dassi, P., Verrotti, A., Marcotulli, D., Canavese, C., Nicita, F., Capuano, A., Marra, C., Fetta, A., Nosadini, M., Sartori, S., Papa, A., Viri, M., Greco, F., Pavone, P., Simonini, G., Matricardi, S., Siquilini, S., Marchese, F., De Grandis, E., Brunenghi, B. M., Malattia, C., Bassanese, F., Bergonzini, P., Bonuccelli, A., Consolini, R., Marseglia, G. L., Peroni, D., Striano, P., Cordelli, D., & Savasta, S. (2021). A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 361-6. https://doi.org/10.1016/j.ejpn.2021.11.002
Orsini, Alessandro, et al. "A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors." European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society vol. 36 (2021): 1-6. doi: https://doi.org/10.1016/j.ejpn.2021.11.002
Orsini A, Foiadelli T, Magistrali M, Carli N, Bagnasco I, Dassi P, Verrotti A, Marcotulli D, Canavese C, Nicita F, Capuano A, Marra C, Fetta A, Nosadini M, Sartori S, Papa A, Viri M, Greco F, Pavone P, Simonini G, Matricardi S, Siquilini S, Marchese F, De Grandis E, Brunenghi BM, Malattia C, Bassanese F, Bergonzini P, Bonuccelli A, Consolini R, Marseglia GL, Peroni D, Striano P, Cordelli D, Savasta S. A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors. Eur J Paediatr Neurol. 2021 Nov 06;36:1-6. doi: 10.1016/j.ejpn.2021.11.002. Epub 2021 Nov 06. PMID: 34768201.
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Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.

Biological & pharmaceutical bulletin

Obara K, Matsuoka Y, Iwata N, Abe Y, Ikegami Y, Shioda N, Hattori Y, Hamamatsu S, Yoshioka K, Yamaki F, Matsuo K, Yoshio T, Tanaka Y.
PMID: 34334499
Biol Pharm Bull. 2021;44(8):1140-1150. doi: 10.1248/bpb.b21-00363.

The clinical applications of antipsychotics for symptoms unrelated to schizophrenia, such as behavioral and psychological symptoms, in patients with Alzheimer's disease, and the likelihood of doctors prescribing antipsychotics for elderly people are increasing. In elderly people, drug-induced and aging-associated...

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Obara K, Matsuoka Y, Iwata N, et al. Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles. Biol Pharm Bull. 2021;44(8):1140-1150doi: 10.1248/bpb.b21-00363.
Obara, K., Matsuoka, Y., Iwata, N., Abe, Y., Ikegami, Y., Shioda, N., Hattori, Y., Hamamatsu, S., Yoshioka, K., Yamaki, F., Matsuo, K., Yoshio, T., & Tanaka, Y. (2021). Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles. Biological & pharmaceutical bulletin, 44(8), 1140-1150. https://doi.org/10.1248/bpb.b21-00363
Obara, Keisuke, et al. "Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles." Biological & pharmaceutical bulletin vol. 44,8 (2021): 1140-1150. doi: https://doi.org/10.1248/bpb.b21-00363
Obara K, Matsuoka Y, Iwata N, Abe Y, Ikegami Y, Shioda N, Hattori Y, Hamamatsu S, Yoshioka K, Yamaki F, Matsuo K, Yoshio T, Tanaka Y. Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles. Biol Pharm Bull. 2021;44(8):1140-1150. doi: 10.1248/bpb.b21-00363. PMID: 34334499.
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A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Orsini A, Foiadelli T, Magistrali M, Carli N, Bagnasco I, Dassi P, Verrotti A, Marcotulli D, Canavese C, Nicita F, Capuano A, Marra C, Fetta A, Nosadini M, Sartori S, Papa A, Viri M, Greco F, Pavone P, Simonini G, Matricardi S, Siquilini S, Marchese F, De Grandis E, Brunenghi BM, Malattia C, Bassanese F, Bergonzini P, Bonuccelli A, Consolini R, Marseglia GL, Peroni D, Striano P, Cordelli D, Savasta S.
PMID: 34768201
Eur J Paediatr Neurol. 2021 Nov 06;36:1-6. doi: 10.1016/j.ejpn.2021.11.002. Epub 2021 Nov 06.

OBJECTIVES: Sydenham's Chorea (SC) is a neuropsychiatric disorder and a major manifestation of acute rheumatic fever. The erroneous assumption that SC is a benign and self-limiting disease, has led to a lack of high-quality scientific evidence of the therapeutical...

Cite
Orsini A, Foiadelli T, Magistrali M, et al. A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors. Eur J Paediatr Neurol. 2021;36:1-6doi: 10.1016/j.ejpn.2021.11.002.
Orsini, A., Foiadelli, T., Magistrali, M., Carli, N., Bagnasco, I., Dassi, P., Verrotti, A., Marcotulli, D., Canavese, C., Nicita, F., Capuano, A., Marra, C., Fetta, A., Nosadini, M., Sartori, S., Papa, A., Viri, M., Greco, F., Pavone, P., Simonini, G., Matricardi, S., Siquilini, S., Marchese, F., De Grandis, E., Brunenghi, B. M., Malattia, C., Bassanese, F., Bergonzini, P., Bonuccelli, A., Consolini, R., Marseglia, G. L., Peroni, D., Striano, P., Cordelli, D., & Savasta, S. (2021). A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 361-6. https://doi.org/10.1016/j.ejpn.2021.11.002
Orsini, Alessandro, et al. "A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors." European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society vol. 36 (2021): 1-6. doi: https://doi.org/10.1016/j.ejpn.2021.11.002
Orsini A, Foiadelli T, Magistrali M, Carli N, Bagnasco I, Dassi P, Verrotti A, Marcotulli D, Canavese C, Nicita F, Capuano A, Marra C, Fetta A, Nosadini M, Sartori S, Papa A, Viri M, Greco F, Pavone P, Simonini G, Matricardi S, Siquilini S, Marchese F, De Grandis E, Brunenghi BM, Malattia C, Bassanese F, Bergonzini P, Bonuccelli A, Consolini R, Marseglia GL, Peroni D, Striano P, Cordelli D, Savasta S. A nationwide study on Sydenham's chorea: Clinical features, treatment and prognostic factors. Eur J Paediatr Neurol. 2021 Nov 06;36:1-6. doi: 10.1016/j.ejpn.2021.11.002. Epub 2021 Nov 06. PMID: 34768201.
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The Pharmacologic Treatment of Stuttering and Its Neuropharmacologic Basis.

Frontiers in neuroscience

Maguire GA, Nguyen DL, Simonson KC, Kurz TL.
PMID: 32292321
Front Neurosci. 2020 Mar 27;14:158. doi: 10.3389/fnins.2020.00158. eCollection 2020.

Stuttering is a DSM V psychiatric condition for which there are no FDA-approved medications for treatment. A growing body of evidence suggests that dopamine antagonist medications are effective in reducing the severity of stuttering symptoms. Stuttering shares many similarities...

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Maguire GA, Nguyen DL, Simonson KC, et al. The Pharmacologic Treatment of Stuttering and Its Neuropharmacologic Basis. Front Neurosci. 2020;14:158doi: 10.3389/fnins.2020.00158.
Maguire, G. A., Nguyen, D. L., Simonson, K. C., & Kurz, T. L. (2020). The Pharmacologic Treatment of Stuttering and Its Neuropharmacologic Basis. Frontiers in neuroscience, 14158. https://doi.org/10.3389/fnins.2020.00158
Maguire, Gerald A, et al. "The Pharmacologic Treatment of Stuttering and Its Neuropharmacologic Basis." Frontiers in neuroscience vol. 14 (2020): 158. doi: https://doi.org/10.3389/fnins.2020.00158
Maguire GA, Nguyen DL, Simonson KC, Kurz TL. The Pharmacologic Treatment of Stuttering and Its Neuropharmacologic Basis. Front Neurosci. 2020 Mar 27;14:158. doi: 10.3389/fnins.2020.00158. eCollection 2020. PMID: 32292321; PMCID: PMC7118465.
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