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Showing 1 to 12 of 199 entries
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Factor XIII-A Val34Leu polymorphism might beassociated with myocardial infarction risk: an updated meta-analysis.

International journal of clinical and experimental medicine

Wang G, Zou Z, Ji X, Ni Q, Ma Z.
PMID: 25664069
Int J Clin Exp Med. 2014 Dec 15;7(12):5547-52. eCollection 2014.

Although many epidemiologic studies have investigated the FXIII-A Val34Leu polymorphism and their associations with myocardial infarction (MI), definite conclusions can't be drawn. To clarify the effects of FXIII-A Val34Leu polymorphism on the risk of MI, a meta-analysis was performed....

Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?.

Journal of blood medicine

Korte W.
PMID: 25031548
J Blood Med. 2014 Jul 09;5:107-13. doi: 10.2147/JBM.S35395. eCollection 2014.

Circulating factor XIII (FXIII) consists of two active (A) and two carrier (B) subunits in tetrameric form. Congenital FXIII deficiency is a rare autosomal-recessive trait that mostly results from an FXIII A-subunit deficiency. Classic coagulation assays, such as prothrombin...

MOLECULAR MODELLING, 3D-QSAR, AND DRUG DOCKING STUDIES ON THE ROLE OF NATURAL ANTICOAGULANT COMPOUNDS IN ANTITHROMBOTIC THERAPY.

International journal of pharmaceutical sciences and research

Kakarla P, Devireddy AR, Inupakutika MA, Cheeti UR, Floyd JT, Mun MM, Vigil RN, Hunter RP, Varela MF.
PMID: 25750914
Int J Pharm Sci Res. 2014;5(10):4141-4152.

Thromboembolic disorders are the leading cause of human mortality. Therefore, development of effective anticoagulant therapy is critical. Factor XIIIA (FXIIIA) protein is a crucial factor in the blood coagulation cascade, and hence it is a vital target for evolution...

Once daily ledipasvir/sofosbuvir fixed-dose combination with ribavirin in patients with inherited bleeding disorders and hepatitis C genotype 1 infection.

Haemophilia : the official journal of the World Federation of Hemophilia

Stedman CAM, Hyland RH, Ding X, Pang PS, McHutchison JG, Gane EJ.
PMID: 26315711
Haemophilia. 2016 Mar;22(2):214-217. doi: 10.1111/hae.12791. Epub 2015 Aug 28.

AIM: People with inherited bleeding disorders have been disproportionally affected by HCV. We assessed the fixed-dose combination of the NS5A inhibitor ledipasvir (LDV) with the NS5B polymerase inhibitor sofosbuvir (SOF) with ribavirin (RBV) in patients with genotype 1 HCV...

Experimentally induced cerebral aneurysms as model for non-surgical treatment.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Hashimoto N, Hazama F.
PMID: 18638772
J Clin Neurosci. 1994 Oct;1(4):266-73. doi: 10.1016/0967-5868(94)90068-x.

This article summarizes the results of our experimental studies on the pathogenesis of cerebral aneurysm. Experimentally induced aneurysms in rats and in monkeys resemble those of human cases both in location and in microscopic structure. By studying early changes...

Response: Factor XIIIa--Expressing Dermal Dendrocytes in AIDS-Associated Cutaneous Kaposi's Sarcomas.

Science (New York, N.Y.)

Gallo RC, Salahuddin SZ, Nakamura S.
PMID: 17751283
Science. 1989 Mar 31;243(4899):1737. doi: 10.1126/science.243.4899.1737.

No abstract available.

Human epidermal transglutaminase.

The Journal of investigative dermatology

Goldsmith LA.
PMID: 20479731
J Invest Dermatol. 1983 Jun;80(1):39s-41s. doi: 10.1038/jid.1983.10.

Epidermal transglutaminase and its structural consequences were first described by studies of the Massachusetts General Hospital dermatology research laboratories in the early 1970s. The enzyme catalyzes an irreversible and necessary step in epidermal terminal differentiation. These features of the...

Cytomorphology of Erdheim-Chester disease presenting as a retroperitoneal soft tissue lesion.

CytoJournal

Purgina B, Jaffe R, Monaco SE, Khalbuss WE, Beasley HS, Dunn JA, Pantanowitz L.
PMID: 22279491
Cytojournal. 2011;8:22. doi: 10.4103/1742-6413.91242. Epub 2011 Dec 27.

Erdheim-Chester disease (ECD) is a rare, multisystem disorder of macrophages. Patients manifest with histiocytic infiltrates that lead to xanthogranulomatous lesions in multiple organ systems. The cytologic features of this disorder are not well characterized. As a result, the cytologic...

Screening tests of the hemostatic system.

Canadian family physician Medecin de famille canadien

Hayne OA.
PMID: 20469270
Can Fam Physician. 1976 Dec;22:33-5.

The hemostatic system consists of the subcutaneous tissue/vessel wall/platelet system and the coagulation cascade. Hemostasis occurs initially through the interaction between circulating platelets and subendothelial collagen, so that a platelet plug is formed. The platelet plug produces hemostasis, but...

Coming full circle with factor XIII.

Blood

Lord ST.
PMID: 21436080
Blood. 2011 Mar 24;117(12):3255-6. doi: 10.1182/blood-2011-02-332627.

No abstract available.

Malignant melanoma and its stromal nonimmune microecosystem.

Journal of oncology

Piérard GE, Piérard-Franchimont C, Delvenne P.
PMID: 22811710
J Oncol. 2012;2012:584219. doi: 10.1155/2012/584219. Epub 2012 Jun 28.

In recent years, rapid advances were reached in the understanding of a series of biologic signals influencing cutaneous malignant melanoma (CMM) cells. CMM is in close contact with a peculiar dermal extracellular matrix (ECM). Stromal cells store and release...

Acute Abdomen in a Young Girl with Factor XIII Deficiency Perianesthetic Issues.

Journal of obstetrics and gynaecology of India

Chakravarty C, Sivakumaran S, Punk J, Singh N, Pandey R, Darlong V.
PMID: 23543997
J Obstet Gynaecol India. 2012 Apr;62(2):205-6. doi: 10.1007/s13224-011-0103-y. Epub 2012 Mar 07.

No abstract available.

Showing 1 to 12 of 199 entries