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Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates.

Environmental toxicology and pharmacology

Coleman MD, Khalaf LF, Nicholls PJ.
PMID: 21782676
Environ Toxicol Pharmacol. 2003 Dec;15(1):27-32. doi: 10.1016/j.etap.2003.08.003.

A model of human leucopenia has been developed further in the female mouse. Following daily administration to female mice of 50 mg/kg of the aromatase inhibitor aminoglutethimide, significant falls in platelet and white cell counts occurred after 2 and...

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Coleman MD, Khalaf LF, Nicholls PJ. Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates. Environ Toxicol Pharmacol. 2003;15(1):27-32doi: 10.1016/j.etap.2003.08.003.
Coleman, M. D., Khalaf, L. F., & Nicholls, P. J. (2003). Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates. Environmental toxicology and pharmacology, 15(1), 27-32. https://doi.org/10.1016/j.etap.2003.08.003
Coleman, Michael D, et al. "Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates." Environmental toxicology and pharmacology vol. 15,1 (2003): 27-32. doi: https://doi.org/10.1016/j.etap.2003.08.003
Coleman MD, Khalaf LF, Nicholls PJ. Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates. Environ Toxicol Pharmacol. 2003 Dec;15(1):27-32. doi: 10.1016/j.etap.2003.08.003. PMID: 21782676.
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Peritoneal Dialysis.

Canadian Medical Association journal

Ellis KG, Lea RG, Drysdale RD.
PMID: 20327513
Can Med Assoc J. 1963 May 04;88(18):928-31.

Three patients with chronic uremia and one patient with glutethimide intoxication were treated by peritoneal dialysis at the Prince Edward Island Hospital, Charlottetown. The procedure was discovered to be technically simple and was carried on in one instance for...

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Ellis KG, Lea RG, Drysdale RD. Peritoneal Dialysis. Can Med Assoc J. 1963;88(18):928-31
Ellis, K. G., Lea, R. G., & Drysdale, R. D. (1963). Peritoneal Dialysis. Canadian Medical Association journal, 88(18), 928-31.
Ellis, K G, et al. "Peritoneal Dialysis." Canadian Medical Association journal vol. 88,18 (1963): 928-31.
Ellis KG, Lea RG, Drysdale RD. Peritoneal Dialysis. Can Med Assoc J. 1963 May 04;88(18):928-31. PMID: 20327513; PMCID: PMC1921279.
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The determination of (R)- and (S)-glutethimide and the corresponding 4-hydroxyglutethimide metabolises in human serum and urine using a Pirkle-type HPLC chiral stationary phase.

Journal of pharmaceutical and biomedical analysis

Wainer IW, Alembik MC, Fischer LJ.
PMID: 16867472
J Pharm Biomed Anal. 1987;5(7):735-40. doi: 10.1016/0731-7085(87)80088-2.

No abstract available.

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Wainer IW, Alembik MC, Fischer LJ. The determination of (R)- and (S)-glutethimide and the corresponding 4-hydroxyglutethimide metabolises in human serum and urine using a Pirkle-type HPLC chiral stationary phase. J Pharm Biomed Anal. 1987;5(7):735-40doi: 10.1016/0731-7085(87)80088-2.
Wainer, I. W., Alembik, M. C., & Fischer, L. J. (1987). The determination of (R)- and (S)-glutethimide and the corresponding 4-hydroxyglutethimide metabolises in human serum and urine using a Pirkle-type HPLC chiral stationary phase. Journal of pharmaceutical and biomedical analysis, 5(7), 735-40. https://doi.org/10.1016/0731-7085(87)80088-2
Wainer, I W, et al. "The determination of (R)- and (S)-glutethimide and the corresponding 4-hydroxyglutethimide metabolises in human serum and urine using a Pirkle-type HPLC chiral stationary phase." Journal of pharmaceutical and biomedical analysis vol. 5,7 (1987): 735-40. doi: https://doi.org/10.1016/0731-7085(87)80088-2
Wainer IW, Alembik MC, Fischer LJ. The determination of (R)- and (S)-glutethimide and the corresponding 4-hydroxyglutethimide metabolises in human serum and urine using a Pirkle-type HPLC chiral stationary phase. J Pharm Biomed Anal. 1987;5(7):735-40. doi: 10.1016/0731-7085(87)80088-2. PMID: 16867472.
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Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.

Journal of clinical pharmacology

Doyno CR, White CM.
PMID: 34396551
J Clin Pharmacol. 2021 Aug;61:S114-S128. doi: 10.1002/jcph.1922.

There are many nonopioid central nervous system depressant substances that share a gamma-aminobutyric acid (GABA) receptor-related mechanism of action. These sedatives-hypnotics can be indicated to treat anxiety, seizures, depression, and insomnia but are also used as substances of abuse...

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Doyno CR, White CM. Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank. J Clin Pharmacol. 2021;61:S114-S128doi: 10.1002/jcph.1922.
Doyno, C. R., & White, C. M. (2021). Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank. Journal of clinical pharmacology, 61S114-S128. https://doi.org/10.1002/jcph.1922
Doyno, Cassandra R, and White, C Michael. "Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank." Journal of clinical pharmacology vol. 61 (2021): S114-S128. doi: https://doi.org/10.1002/jcph.1922
Doyno CR, White CM. Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank. J Clin Pharmacol. 2021 Aug;61:S114-S128. doi: 10.1002/jcph.1922. PMID: 34396551.
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Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC.

Talanta

Ali I, Naim L, Ghanem A, Aboul-Enein HY.
PMID: 18970673
Talanta. 2006 Jun 15;69(4):1013-7. doi: 10.1016/j.talanta.2005.12.004. Epub 2006 Jan 10.

Recently, two new immobilized polysaccharides based CSPs, namely tris-(3,5-dimethylphenylcarbamate) derivatives of amylose and cellulose known as Chiralpak IA and Chiralpak IB were introduced, which may be used with a wide range of solvents including standard and prohibited ones. Several...

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Ali I, Naim L, Ghanem A, et al. Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC. Talanta. 2006;69(4):1013-7doi: 10.1016/j.talanta.2005.12.004.
Ali, I., Naim, L., Ghanem, A., & Aboul-Enein, H. Y. (2006). Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC. Talanta, 69(4), 1013-7. https://doi.org/10.1016/j.talanta.2005.12.004
Ali, Imran, et al. "Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC." Talanta vol. 69,4 (2006): 1013-7. doi: https://doi.org/10.1016/j.talanta.2005.12.004
Ali I, Naim L, Ghanem A, Aboul-Enein HY. Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC. Talanta. 2006 Jun 15;69(4):1013-7. doi: 10.1016/j.talanta.2005.12.004. Epub 2006 Jan 10. PMID: 18970673.
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Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide.

Toxicology in vitro : an international journal published in association with BIBRA

Ali H, Khalaf L, Nicholls PJ, Poole A.
PMID: 20702198
Toxicol In Vitro. 1990;4(4):381-3. doi: 10.1016/0887-2333(90)90084-7.

The aromatase inhibitor, aminoglutethimide, causes a blood dyscrasia in about 1% of women taking the drug for the treatment of advanced breast cancer. The parent compound, glutethimide, is known not to possess this toxic action. The effect of both...

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Ali H, Khalaf L, Nicholls PJ, et al. Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide. Toxicol In Vitro. 1990;4(4):381-3doi: 10.1016/0887-2333(90)90084-7.
Ali, H., Khalaf, L., Nicholls, P. J., & Poole, A. (1990). Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide. Toxicology in vitro : an international journal published in association with BIBRA, 4(4), 381-3. https://doi.org/10.1016/0887-2333(90)90084-7
Ali, H, et al. "Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide." Toxicology in vitro : an international journal published in association with BIBRA vol. 4,4 (1990): 381-3. doi: https://doi.org/10.1016/0887-2333(90)90084-7
Ali H, Khalaf L, Nicholls PJ, Poole A. Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide. Toxicol In Vitro. 1990;4(4):381-3. doi: 10.1016/0887-2333(90)90084-7. PMID: 20702198.
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Note on Glutethimide.

Canadian Medical Association journal

Bennett JS.
PMID: 20327235
Can Med Assoc J. 1962 Sep 08;87(10):571.

No abstract available.

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Bennett JS. Note on Glutethimide. Can Med Assoc J. 1962;87(10):571
Bennett, J. S. (1962). Note on Glutethimide. Canadian Medical Association journal, 87(10), 571.
Bennett, J S. "Note on Glutethimide." Canadian Medical Association journal vol. 87,10 (1962): 571.
Bennett JS. Note on Glutethimide. Can Med Assoc J. 1962 Sep 08;87(10):571. PMID: 20327235; PMCID: PMC1849394.
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Showing 1 to 7 of 7 entries