Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 199 entries
Sorted by: Best Match Show Resources per page
Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells.

Oncology letters

Jiang G, Dong S, Yu M, Han X, Zheng C, Zhu X, Tong X.
PMID: 28356970
Oncol Lett. 2017 Feb;13(2):857-866. doi: 10.3892/ol.2016.5471. Epub 2016 Dec 07.

Gap junctions (GJs) serve the principal role in the antineoplastic (cytotoxicity and induced apoptosis) effect of chemical drugs. The aim of the present study was to determine the effect of GJ intercellular communication (GJIC) composed of connexin 43 (Cx43)...

Cite
Jiang G, Dong S, Yu M, et al. Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells. Oncol Lett. 2016;13(2):857-866doi: 10.3892/ol.2016.5471.
Jiang, G., Dong, S., Yu, M., Han, X., Zheng, C., Zhu, X., & Tong, X. (2017). Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells. Oncology letters, 13(2), 857-866. https://doi.org/10.3892/ol.2016.5471
Jiang, Guojun, et al. "Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells." Oncology letters vol. 13,2 (2017): 857-866. doi: https://doi.org/10.3892/ol.2016.5471
Jiang G, Dong S, Yu M, Han X, Zheng C, Zhu X, Tong X. Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells. Oncol Lett. 2017 Feb;13(2):857-866. doi: 10.3892/ol.2016.5471. Epub 2016 Dec 07. PMID: 28356970; PMCID: PMC5351289.
Copy Download .nbib Format: NLM
Unequivocal glycyrrhizin isomer determination and comparative in vitro bioactivities of root extracts in four Glycyrrhiza species.

Journal of advanced research

Farag MA, Porzel A, Wessjohann LA.
PMID: 25685548
J Adv Res. 2015 Jan;6(1):99-104. doi: 10.1016/j.jare.2014.05.001. Epub 2014 May 14.

Glycyrrhiza glabra, commonly known as licorice, is a popular herbal supplement used for the treatment of chronic inflammatory conditions and as sweetener in the food industry. This species contains a myriad of phytochemicals including the major saponin glycoside glycyrrhizin...

Cite
Farag MA, Porzel A, Wessjohann LA. Unequivocal glycyrrhizin isomer determination and comparative in vitro bioactivities of root extracts in four Glycyrrhiza species. J Adv Res. 2014;6(1):99-104doi: 10.1016/j.jare.2014.05.001.
Farag, M. A., Porzel, A., & Wessjohann, L. A. (2015). Unequivocal glycyrrhizin isomer determination and comparative in vitro bioactivities of root extracts in four Glycyrrhiza species. Journal of advanced research, 6(1), 99-104. https://doi.org/10.1016/j.jare.2014.05.001
Farag, Mohamed A, et al. "Unequivocal glycyrrhizin isomer determination and comparative in vitro bioactivities of root extracts in four Glycyrrhiza species." Journal of advanced research vol. 6,1 (2015): 99-104. doi: https://doi.org/10.1016/j.jare.2014.05.001
Farag MA, Porzel A, Wessjohann LA. Unequivocal glycyrrhizin isomer determination and comparative in vitro bioactivities of root extracts in four Glycyrrhiza species. J Adv Res. 2015 Jan;6(1):99-104. doi: 10.1016/j.jare.2014.05.001. Epub 2014 May 14. PMID: 25685548; PMCID: PMC4293670.
Copy Download .nbib Format: NLM
Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice.

Journal of agricultural and food chemistry

Wu CH, Chen AZ, Yen GC.
PMID: 25588318
J Agric Food Chem. 2015 Feb 04;63(4):1200-1209. doi: 10.1021/jf505471a. Epub 2015 Jan 26.

The clinical use of antineoplastic drug cisplatin (CP) is commonly complicated by nephrotoxic side effects that limit its application and therapeutic efficiency. This study used a model of CP-induced renal injury in male BALB/c mice to investigate the protective...

Cite
Wu CH, Chen AZ, Yen GC. Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice. J Agric Food Chem. 2015;63(4):1200-1209doi: 10.1021/jf505471a.
Wu, C. H., Chen, A. Z., & Yen, G. C. (2015). Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice. Journal of agricultural and food chemistry, 63(4), 1200-1209. https://doi.org/10.1021/jf505471a
Wu, Chi-Hao, et al. "Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice." Journal of agricultural and food chemistry vol. 63,4 (2015): 1200-1209. doi: https://doi.org/10.1021/jf505471a
Wu CH, Chen AZ, Yen GC. Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice. J Agric Food Chem. 2015 Feb 04;63(4):1200-1209. doi: 10.1021/jf505471a. Epub 2015 Jan 26. PMID: 25588318.
Copy Download .nbib Format: NLM
Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice.

Frontiers in cellular neuroscience

Barrett JM, Degenaar P, Sernagor E.
PMID: 26379501
Front Cell Neurosci. 2015 Aug 25;9:330. doi: 10.3389/fncel.2015.00330. eCollection 2015.

Retinitis pigmentosa (RP) is a progressive retinal dystrophy that causes visual impairment and eventual blindness. Retinal prostheses are the best currently available vision-restoring treatment for RP, but only restore crude vision. One possible contributing factor to the poor quality...

Cite
Barrett JM, Degenaar P, Sernagor E. Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice. Front Cell Neurosci. 2015;9:330doi: 10.3389/fncel.2015.00330.
Barrett, J. M., Degenaar, P., & Sernagor, E. (2015). Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice. Frontiers in cellular neuroscience, 9330. https://doi.org/10.3389/fncel.2015.00330
Barrett, John M, et al. "Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice." Frontiers in cellular neuroscience vol. 9 (2015): 330. doi: https://doi.org/10.3389/fncel.2015.00330
Barrett JM, Degenaar P, Sernagor E. Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice. Front Cell Neurosci. 2015 Aug 25;9:330. doi: 10.3389/fncel.2015.00330. eCollection 2015. PMID: 26379501; PMCID: PMC4548307.
Copy Download .nbib Format: NLM
18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation.

Genes & nutrition

Mahmoud AM, Al Dera HS.
PMID: 26386843
Genes Nutr. 2015 Nov;10(6):41. doi: 10.1007/s12263-015-0491-1. Epub 2015 Sep 19.

18β-Glycyrrhetinic acid (18β-GA) has been proposed as a promising hepatoprotective agent. The current study aimed to investigate the protective action and the possible mechanisms of 18β-GA against cyclophosphamide (CP)-induced liver injury in rats, focusing on the role of peroxisome...

Cite
Mahmoud AM, Al Dera HS. 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes Nutr. 2015;10(6):41doi: 10.1007/s12263-015-0491-1.
Mahmoud, A. M., & Al Dera, H. S. (2015). 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes & nutrition, 10(6), 41. https://doi.org/10.1007/s12263-015-0491-1
Mahmoud, Ayman M, and Al Dera, Hussein S. "18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation." Genes & nutrition vol. 10,6 (2015): 41. doi: https://doi.org/10.1007/s12263-015-0491-1
Mahmoud AM, Al Dera HS. 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation. Genes Nutr. 2015 Nov;10(6):41. doi: 10.1007/s12263-015-0491-1. Epub 2015 Sep 19. PMID: 26386843; PMCID: PMC4575654.
Copy Download .nbib Format: NLM
Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects.

Frontiers in pharmacology

Mizoguchi K, Ikarashi Y.
PMID: 28377723
Front Pharmacol. 2017 Mar 21;8:149. doi: 10.3389/fphar.2017.00149. eCollection 2017.

Yokukansan (YKS), a traditional Japanese Kampo medicine, has indications for use in night crying and irritability in children, as well as neurosis and insomnia. It is currently also used for the remedy of the behavioral and psychological symptoms of...

Cite
Mizoguchi K, Ikarashi Y. Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects. Front Pharmacol. 2017;8:149doi: 10.3389/fphar.2017.00149.
Mizoguchi, K., & Ikarashi, Y. (2017). Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects. Frontiers in pharmacology, 8149. https://doi.org/10.3389/fphar.2017.00149
Mizoguchi, Kazushige, and Ikarashi, Yasushi. "Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects." Frontiers in pharmacology vol. 8 (2017): 149. doi: https://doi.org/10.3389/fphar.2017.00149
Mizoguchi K, Ikarashi Y. Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects. Front Pharmacol. 2017 Mar 21;8:149. doi: 10.3389/fphar.2017.00149. eCollection 2017. PMID: 28377723; PMCID: PMC5359390.
Copy Download .nbib Format: NLM
Hematopoiesis: Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hemopoietic Stem Cells.

Hematology (Amsterdam, Netherlands)

Ploemacher RE, Mayen AE, De Koning AE, Krenacs T, Rosendaal M.
PMID: 11399609
Hematology. 2000;5(2):133-147. doi: 10.1080/10245332.2000.11746498.

The 80-100 fold increased immunohistological expression of the Gap Junction (GJ) protein Connexin-43 in murine bone marrow during the neonatal period and directly following cytoreductive treatment of adult mice suggests that the regulation of stem cell proliferation may involve...

Cite
Ploemacher RE, Mayen AE, De Koning AE, et al. Hematopoiesis: Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hemopoietic Stem Cells. Hematology. 2000;5(2):133-147doi: 10.1080/10245332.2000.11746498.
Ploemacher, R. E., Mayen, A. E., De Koning, A. E., Krenacs, T., & Rosendaal, M. (2000). Hematopoiesis: Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hemopoietic Stem Cells. Hematology (Amsterdam, Netherlands), 5(2), 133-147. https://doi.org/10.1080/10245332.2000.11746498
Ploemacher, ROB E., et al. "Hematopoiesis: Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hemopoietic Stem Cells." Hematology (Amsterdam, Netherlands) vol. 5,2 (2000): 133-147. doi: https://doi.org/10.1080/10245332.2000.11746498
Ploemacher RE, Mayen AE, De Koning AE, Krenacs T, Rosendaal M. Hematopoiesis: Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hemopoietic Stem Cells. Hematology. 2000;5(2):133-147. doi: 10.1080/10245332.2000.11746498. PMID: 11399609.
Copy Download .nbib Format: NLM
Assay methods for antihepatotoxic activity using peroxide-induced cytotoxicity in primary cultured hepatocytes1.

Planta medica

Kiso Y, Kato O, Hikino H.
PMID: 17340401
Planta Med. 1985 Feb;51(1):50-2. doi: 10.1055/s-2007-969391.

Conditions were investigated to devise IN VITRO assay methods for antihepatotoxic activity using peroxide-induced damage in primary cultured rat liver cells. Utilizing linoleic acid peroxide, benzoyl peroxide, cumene hydroperoxide and adenosine diphosphate/Fe (3+), satisfactory assay procedures were established. Some...

Cite
Kiso Y, Kato O, Hikino H. Assay methods for antihepatotoxic activity using peroxide-induced cytotoxicity in primary cultured hepatocytes1. Planta Med. 1985;51(1):50-2doi: 10.1055/s-2007-969391.
Kiso, Y., Kato, O., & Hikino, H. (1985). Assay methods for antihepatotoxic activity using peroxide-induced cytotoxicity in primary cultured hepatocytes1. Planta medica, 51(1), 50-2. https://doi.org/10.1055/s-2007-969391
Kiso, Y, et al. "Assay methods for antihepatotoxic activity using peroxide-induced cytotoxicity in primary cultured hepatocytes1." Planta medica vol. 51,1 (1985): 50-2. doi: https://doi.org/10.1055/s-2007-969391
Kiso Y, Kato O, Hikino H. Assay methods for antihepatotoxic activity using peroxide-induced cytotoxicity in primary cultured hepatocytes1. Planta Med. 1985 Feb;51(1):50-2. doi: 10.1055/s-2007-969391. PMID: 17340401.
Copy Download .nbib Format: NLM
Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP-Induced Cell Death in PC12 Cells.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Kim YJ, Lee CS.
PMID: 20157396
Korean J Physiol Pharmacol. 2008 Apr;12(2):65-71. doi: 10.4196/kjpp.2008.12.2.65. Epub 2008 Apr 30.

The present study examined the inhibitory effect of licorice compounds glycyrrhizin and a metabolite 18beta-glycyrrhetinic acid on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse and on the 1-methyl-4-phenylpyridinium (MPP(+))-induced cell death in differentiated PC12 cells. MPTP treatment increased...

Cite
Kim YJ, Lee CS. Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP-Induced Cell Death in PC12 Cells. Korean J Physiol Pharmacol. 2008;12(2):65-71doi: 10.4196/kjpp.2008.12.2.65.
Kim, Y. J., & Lee, C. S. (2008). Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP-Induced Cell Death in PC12 Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 12(2), 65-71. https://doi.org/10.4196/kjpp.2008.12.2.65
Kim, Yun Jeong, and Lee, Chung Soo. "Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP-Induced Cell Death in PC12 Cells." The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol. 12,2 (2008): 65-71. doi: https://doi.org/10.4196/kjpp.2008.12.2.65
Kim YJ, Lee CS. Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP-Induced Cell Death in PC12 Cells. Korean J Physiol Pharmacol. 2008 Apr;12(2):65-71. doi: 10.4196/kjpp.2008.12.2.65. Epub 2008 Apr 30. PMID: 20157396; PMCID: PMC2817536.
Copy Download .nbib Format: NLM
1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid.

Acta crystallographica. Section E, Structure reports online

Hu J, Yu L, Wang R, Ju Y.
PMID: 21582833
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 10;65:o1547. doi: 10.1107/S1600536809020996.

THE TITLE COMPOUND [SYSTEMATIC NAME: 11-oxo-2,3-(oxy-dinitrilo)olean-12-en-29-oic acid], C(30)H(42)N(2)O(4), contains a linear array of five six-membered rings and a five-membered heterocyclic ring. The C ring, containing an α,β-unsaturated ketone, has a slightly distorted half-chair conformation, as does the A ring,...

Cite
Hu J, Yu L, Wang R, et al. 1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid. Acta Crystallogr Sect E Struct Rep Online. 2009;65:o1547doi: 10.1107/S1600536809020996.
Hu, J., Yu, L., Wang, R., & Ju, Y. (2009). 1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid. Acta crystallographica. Section E, Structure reports online, 65o1547. https://doi.org/10.1107/S1600536809020996
Hu, Jun, et al. "1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid." Acta crystallographica. Section E, Structure reports online vol. 65 (2009): o1547. doi: https://doi.org/10.1107/S1600536809020996
Hu J, Yu L, Wang R, Ju Y. 1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid. Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 10;65:o1547. doi: 10.1107/S1600536809020996. PMID: 21582833; PMCID: PMC2969501.
Copy Download .nbib Format: NLM
Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex.

Bioinformation

Yamaguchi H, Kidachi Y, Kamiie K, Noshita T, Umetsu H.
PMID: 23275711
Bioinformation. 2012;8(23):1147-53. doi: 10.6026/97320630081147. Epub 2012 Nov 23.

UNLABELLED: Structural analysis of the high-mobility group protein B1 (HMGB1)-DNA complex and a docking simulation between glycyrrhetinic acid (GA) and the HMGB1-DNA complex were performed with a software package the Molecular Operating Environment (MOE). An HMGB1-DNA (PDB code: 2GZK)...

Cite
Yamaguchi H, Kidachi Y, Kamiie K, et al. Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex. Bioinformation. 2012;8(23):1147-53doi: 10.6026/97320630081147.
Yamaguchi, H., Kidachi, Y., Kamiie, K., Noshita, T., & Umetsu, H. (2012). Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex. Bioinformation, 8(23), 1147-53. https://doi.org/10.6026/97320630081147
Yamaguchi, Hideaki, et al. "Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex." Bioinformation vol. 8,23 (2012): 1147-53. doi: https://doi.org/10.6026/97320630081147
Yamaguchi H, Kidachi Y, Kamiie K, Noshita T, Umetsu H. Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex. Bioinformation. 2012;8(23):1147-53. doi: 10.6026/97320630081147. Epub 2012 Nov 23. PMID: 23275711; PMCID: PMC3530883.
Copy Download .nbib Format: NLM
[Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells].

Zhongguo fei ai za zhi = Chinese journal of lung cancer

Huang W, Huang J, Zhang D, Zhang R, Liao Z.
PMID: 21272475
Zhongguo Fei Ai Za Zhi. 2003 Aug 20;6(4):254-7. doi: 10.3779/j.issn.1009-3419.2003.04.02.

BACKGROUND: To study the anti-invasive effects and its mechanism and apoptosis induction of pentacyclic triterpenoid including glycyrrhizin (GL), 18β-glycyrrhetinic acid (GA), ursolic acid (UA) and oleanolic acid (OA) in highly potentially metastatic lung cancer cell line (PGCL3).METHODS: The invasive...

Cite
Huang W, Huang J, Zhang D, et al. [Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells]. Zhongguo Fei Ai Za Zhi. 2003;6(4):254-7doi: 10.3779/j.issn.1009-3419.2003.04.02.
Huang, W., Huang, J., Zhang, D., Zhang, R., & Liao, Z. (2003). [Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells]. Zhongguo fei ai za zhi = Chinese journal of lung cancer, 6(4), 254-7. https://doi.org/10.3779/j.issn.1009-3419.2003.04.02
Huang, Wei, et al. "[Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells]." Zhongguo fei ai za zhi = Chinese journal of lung cancer vol. 6,4 (2003): 254-7. doi: https://doi.org/10.3779/j.issn.1009-3419.2003.04.02
Huang W, Huang J, Zhang D, Zhang R, Liao Z. [Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells]. Zhongguo Fei Ai Za Zhi. 2003 Aug 20;6(4):254-7. doi: 10.3779/j.issn.1009-3419.2003.04.02. Chinese. PMID: 21272475.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 199 entries