Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 58 entries
Sorted by: Best Match Show Resources per page
Changes in metabolic risk factors over 10 years and their associations with late-life cognitive performance: The Multi-Ethnic Study of Atherosclerosis.

Alzheimer's & dementia (Amsterdam, Netherlands)

Hughes TM, Craft S, Baker LD, Espeland MA, Rapp SR, Sink KM, Bertoni AG, Burke GL, Gottesman RF, Michos ED, Luchsinger JA, Fitzpatrick AL, Hayden KM.
PMID: 28435852
Alzheimers Dement (Amst). 2017 Mar 31;8:18-25. doi: 10.1016/j.dadm.2017.03.003. eCollection 2017.

BACKGROUND: We examined whether changes in metabolic factors over 10 years were associated with cognitive performance.METHODS: Participants from the Multi-Ethnic Study of Atherosclerosis were followed since baseline (2000-2002) with five clinical examinations. At exam 5 (2010-2012), they received a...

Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.

Psychosomatic medicine

Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eriksson JG, Groop L, Räikkönen K, Lahti J.
PMID: 29280852
Psychosom Med. 2018 Apr;80(3):242-251. doi: 10.1097/PSY.0000000000000555.

OBJECTIVE: Shared genetic background may explain phenotypic associations between depression and Type 2 diabetes (T2D). We aimed to study, on a genome-wide level, if genetic correlation and pleiotropic loci exist between depressive symptoms and T2D or glycemic traits.METHODS: We...

Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study.

Chest

Anderson MR, Kim JS, Allison M, Giles JT, Hoffman EA, Ding J, Barr RG, Podolanczuk A.
PMID: 33844978
Chest. 2021 Aug;160(2):582-594. doi: 10.1016/j.chest.2021.03.058. Epub 2021 Apr 15.

BACKGROUND: Obesity is associated with restrictive ventilatory defects and a faster rate of decline in FVC. This association is not exclusively mediated by mechanical factors and may reflect direct pulmonary injury by adipose-derived mediators.RESEARCH QUESTION: Is adipose tissue involved...

Association of abdominal muscle area and density with glucose regulation: The multi-ethnic study of atherosclerosis (MESA).

Diabetes/metabolism research and reviews

Gold RS, Unkart JT, Larsen BA, Price CA, Cless M, Araneta MRG, Allison MA.
PMID: 34328704
Diabetes Metab Res Rev. 2021 Jul 30;e3488. doi: 10.1002/dmrr.3488. Epub 2021 Jul 30.

AIMS: Previous characterisation of body composition as a type 2 diabetes mellitus (T2DM) risk factor has largely focused on adiposity, but less is known about the independent role of skeletal muscle. We examined associations between abdominal muscle and measures...

Pre-Statistical Considerations for Harmonization of Cognitive Instruments: Harmonization of ARIC, CARDIA, CHS, FHS, MESA, and NOMAS.

Journal of Alzheimer's disease : JAD

Briceño EM, Gross AL, Giordani BJ, Manly JJ, Gottesman RF, Elkind MSV, Sidney S, Hingtgen S, Sacco RL, Wright CB, Fitzpatrick A, Fohner AE, Mosley TH, Yaffe K, Levine DA.
PMID: 34459397
J Alzheimers Dis. 2021;83(4):1803-1813. doi: 10.3233/JAD-210459.

BACKGROUND: Meta-analyses of individuals' cognitive data are increasing to investigate the biomedical, lifestyle, and sociocultural factors that influence cognitive decline and dementia risk. Pre-statistical harmonization of cognitive instruments is a critical methodological step for accurate cognitive data harmonization, yet...

Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome.

EBioMedicine

Zeng Y, Amador C, Gao C, Walker RM, Morris SW, Campbell A, Frkatović A, Madden RA, Adams MJ, He S, Bretherick AD, Hayward C, Porteous DJ, Wilson JF, Evans KL, McIntosh AM, Navarro P, Haley CS.
PMID: 34883445
EBioMedicine. 2021 Dec 05;74:103730. doi: 10.1016/j.ebiom.2021.103730. Epub 2021 Dec 05.

BACKGROUND: parent-of-origin effects (POE) play important roles in complex disease and thus understanding their regulation and associated molecular and phenotypic variation are warranted. Previous studies mainly focused on the detection of genomic regions or phenotypes regulated by POE. Understanding...

Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).

Alzheimer's & dementia : the journal of the Alzheimer's Association

Lockhart SN, Schaich CL, Craft S, Sachs BC, Rapp SR, Jung Y, Whitlow CT, Solingapuram Sai KK, Cleveland M, Williams BJ, Burke GL, Bertoni A, Hayden KM, Hughes TM.
PMID: 34482601
Alzheimers Dement. 2021 Sep 05; doi: 10.1002/alz.12429. Epub 2021 Sep 05.

INTRODUCTION: Little is known about how antecedent vascular risk factor (VRF) profiles impact late-life brain health.METHODS: We examined baseline VRFs, and cognitive testing and neuroimaging measures (β-amyloid [Aβ] PET, MRI) in a diverse longitudinal cohort (N = 159; 50%...

Stratifying the Risk of Cardiovascular Disease in Obstructive Sleep Apnea Using Machine Learning.

The Laryngoscope

Gourishetti SC, Taylor R, Isaiah A.
PMID: 34487556
Laryngoscope. 2022 Jan;132(1):234-241. doi: 10.1002/lary.29852. Epub 2021 Sep 06.

OBJECTIVES/HYPOTHESIS: Obstructive sleep apnea (OSA) is associated with higher risk of morbidity and mortality related to cardiovascular disease (CVD). Due to overlapping clinical risk factors, identifying high-risk patients with OSA who are likely to develop CVD remains challenging. We...

Associations of sleep duration and sleep-wake rhythm with lung parenchymal abnormalities on computed tomography: The MESA study.

Journal of sleep research

Kim JS, Dashti HS, Huang T, Cade BE, Podolanczuk AJ, O'Hearn DJ, Hoffman EA, Wang H, Blaikley J, Barr RG, Redline S.
PMID: 34498326
J Sleep Res. 2021 Sep 09;e13475. doi: 10.1111/jsr.13475. Epub 2021 Sep 09.

Impairment of the circadian rhythm promotes lung inflammation and fibrosis in pre-clinical models. We aimed to examine whether short and/or long sleep duration and other markers of sleep-wake patterns are associated with a greater burden of lung parenchymal abnormalities...

Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study.

Chest

Anderson MR, Kim JS, Allison M, Giles JT, Hoffman EA, Ding J, Barr RG, Podolanczuk A.
PMID: 33844978
Chest. 2021 Aug;160(2):582-594. doi: 10.1016/j.chest.2021.03.058. Epub 2021 Apr 15.

BACKGROUND: Obesity is associated with restrictive ventilatory defects and a faster rate of decline in FVC. This association is not exclusively mediated by mechanical factors and may reflect direct pulmonary injury by adipose-derived mediators.RESEARCH QUESTION: Is adipose tissue involved...

Health Literacy Within a Diverse Community-Based Cohort: The Multi-Ethnic Study of Atherosclerosis.

Journal of immigrant and minority health

Anderson MD, Merkin SS, Everson-Rose SA, Widome R, Seeman T, Magnani JW, Rodriguez CJ, Lutsey PL.
PMID: 33206278
J Immigr Minor Health. 2021 Aug;23(4):659-667. doi: 10.1007/s10903-020-01123-1. Epub 2020 Nov 18.

BACKGROUND: Health literacy has yet to be described in a non-clinical, racially diverse, community-based cohort.METHODS: Four questions assessing health literacy were asked during annual phone encounters with Multi-Ethnic Study of Atherosclerosis (MESA) participants between 2016 and 2018 (n =...

Reproducibility of global electrical heterogeneity measurements on 12-lead ECG: The Multi-Ethnic Study of Atherosclerosis.

Journal of electrocardiology

Haq KT, Lutz KJ, Peters KK, Craig NE, Mitchell E, Desai AK, Stencel NWL, Soliman EZ, Lima JAC, Tereshchenko LG.
PMID: 34626835
J Electrocardiol. 2021 Nov-Dec;69:96-104. doi: 10.1016/j.jelectrocard.2021.09.014. Epub 2021 Oct 02.

OBJECTIVE: Vectorcardiographic (VCG) global electrical heterogeneity (GEH) metrics showed clinical usefulness. We aimed to assess the reproducibility of GEH metrics.METHODS: GEH was measured on two 10-s 12‑lead ECGs recorded on the same day in 4316 participants of the Multi-Ethnic...

Showing 1 to 12 of 58 entries