Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 5 of 5 entries
Sorted by: Best Match Show Resources per page
Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout .

ImmunoHorizons

Webb LM, Phythian-Adams AT, Costain AH, Brown SL, Lundie RJ, Forde-Thomas J, Cook PC, Jackson-Jones LH, Marley AK, Smits HH, Hoffmann KF, Tait Wojno ED, MacDonald AS.
PMID: 34462311
Immunohorizons. 2021 Aug 30;5(8):721-732. doi: 10.4049/immunohorizons.2100071.

Plasmacytoid dendritic cells (pDCs) are potent producers of type I IFN (IFN-I) during viral infection and respond to IFN-I in a positive feedback loop that promotes their function. IFN-I shapes dendritic cell responses during helminth infection, impacting their ability...

Schistosome tegumental ecto-apyrase (SmATPDase1) degrades exogenous pro-inflammatory and pro-thrombotic nucleotides.

PeerJ

Da'dara AA, Bhardwaj R, Ali YB, Skelly PJ.
PMID: 24711968
PeerJ. 2014 Mar 18;2:e316. doi: 10.7717/peerj.316. eCollection 2014.

Schistosomes are parasitic worms that can survive in the hostile environment of the human bloodstream where they appear refractory to both immune elimination and thrombus formation. We hypothesize that parasite migration in the bloodstream can stress the vascular endothelium...

Development of a novel real-time polymerase chain reaction assay for the sensitive detection of Schistosoma japonicum in human stool.

PLoS neglected tropical diseases

Halili S, Grant JR, Pilotte N, Gordon CA, Williams SA.
PMID: 34695134
PLoS Negl Trop Dis. 2021 Oct 25;15(10):e0009877. doi: 10.1371/journal.pntd.0009877. eCollection 2021 Oct.

BACKGROUND: Elimination and control of Schistosoma japonicum, the most virulent of the schistosomiasis-causing blood flukes, requires the development of sensitive and specific diagnostic tools capable of providing an accurate measurement of the infection prevalence in endemic areas. Typically, detection...

Role of vascular endothelial growth factor signaling in Schistosoma-induced experimental pulmonary hypertension.

Pulmonary circulation

Chabon JJ, Gebreab L, Kumar R, Debella E, Tanaka T, Koyanagi D, Rodriguez Garcia A, Sanders L, Perez M, Tuder RM, Graham BB.
PMID: 25006448
Pulm Circ. 2014 Jun;4(2):289-99. doi: 10.1086/675992.

There is significant evidence that Th2 (T helper 2)-mediated inflammation supports the pathogenesis of both human and experimental animal models of pulmonary hypertension (PH). A key immune regulator is vascular endothelial growth factor (VEGF), which is produced by Th2...

A furoxan-amodiaquine hybrid as a potential therapeutic for three parasitic diseases().

MedChemComm

Mott BT, Cheng KC, Guha R, Kommer VP, Williams DL, Vermeire JJ, Cappello M, Maloney DJ, Rai G, Jadhav A, Simeonov A, Inglese J, Posner GH, Thomas CJ.
PMID: 23205265
Medchemcomm. 2012 Dec;3(12):1505-1511. doi: 10.1039/C2MD20238G.

Parasitic diseases continue to have a devastating impact on human populations worldwide. Lack of effective treatments, the high cost of existing ones, and frequent emergence of resistance to these agents provide a strong argument for the development of novel...

Showing 1 to 5 of 5 entries