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Showing 1 to 10 of 10 entries
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Behçet's Disease: Do Natural Killer Cells Play a Significant Role?.

Frontiers in immunology

Petrushkin H, Hasan MS, Stanford MR, Fortune F, Wallace GR.
PMID: 25852697
Front Immunol. 2015 Mar 24;6:134. doi: 10.3389/fimmu.2015.00134. eCollection 2015.

Behçet's disease (BD) is a complex inflammatory disease, of unknown etiology. While disease pathogenesis remains unclear, a strong relationship between BD and HLA-B*51 has been established over the last 30 years. A number of theories exist regarding the cause...

HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in Vietnamese.

Asia Pacific allergy

Nguyen DV, Chu HC, Nguyen DV, Phan MH, Craig T, Baumgart K, van Nunen S.
PMID: 25938071
Asia Pac Allergy. 2015 Apr;5(2):68-77. doi: 10.5415/apallergy.2015.5.2.68. Epub 2015 Apr 29.

BACKGROUND: In Vietnam, we observed a high incidence of carbamazepine (CBZ)-induced severe cutaneous adverse drug reactions (SCARs)-Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), and drug-induced hypersensitivity rash with eosinophilia and systemic symptoms (DRESS). In other Asian countries, HLA-B(*)1502 is an...

Investigating the association of Lamotrigine and Phenytoin-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with HLA-B*1502 in Iranian population.

Experimental dermatology

Sabourirad S, Mortezaee R, Mojarad M, Eslahi A, Shahrokhi Y, Kiafar B, Jarahi L, Afkhami Ardakani S, Farrokhi S.
PMID: 33217035
Exp Dermatol. 2021 Feb;30(2):284-287. doi: 10.1111/exd.14240. Epub 2020 Dec 04.

Previous studies have found an association between HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS)/ toxic epidermal necrosis (TEN) spectrum in Han Chinese populations. This study aims to investigate the association between HLA-B*1502 and lamotrigine- or phenytoin- induced SJS/TEN in...

Antibodies to cryptic epitopes on HLA class I and class II heavy chains bound to single antigen beads: Clinically relevant?.

Transplant immunology

Ravindranath MH, Filippone EJ, Amato-Menker CJ, Arosa FA, Das B, Ou Y, Norin AJ.
PMID: 34656784
Transpl Immunol. 2021 Dec;69:101482. doi: 10.1016/j.trim.2021.101482. Epub 2021 Oct 14.

Cell surface HLA class I consists of trimers, i.e., alpha - heavy chain, beta - 2 - microglobulin, and a peptide, termed closed conformers (CC) on non-activated lymphocytes. HLA class I and class II may also exist, respectively, as...

Association of Bw4/Bw6 mismatch across class I HLA loci with renal graft outcomes in first time transplants.

Human immunology

Tang MS, Wang M, Chang SH, Alhamad T, Liu C.
PMID: 34362574
Hum Immunol. 2021 Oct;82(10):767-774. doi: 10.1016/j.humimm.2021.07.008. Epub 2021 Aug 03.

Bw4 and Bw6 are strongly immunogenic epitopes routinely assigned based on HLA-B typing results per Organ Procurement and Transplantation Network (OPTN) policies. These public epitopes and their variants are shared by some cross-reactive HLA-A and -C antigens. Although epitope...

Identification of five novel HLA-B alleles in donors from the Colombian Bone Marrow Donor Registry.

HLA

Hernández DG, Camacho Ramírez N, Mosquera Martínez M, Cendales PA, Camacho BA.
PMID: 34931486
HLA. 2021 Dec 20; doi: 10.1111/tan.14516. Epub 2021 Dec 20.

Identification of 5 novel HLA-B alleles in 5 samples from Colombian bone marrow donors. This article is protected by copyright. All rights reserved.

Frequencies of HLA-A and HLA-B alleles in a Mexico City mestizo sample.

American journal of human biology : the official journal of the Human Biology Council

Weckmann AL, Vargas-Alarcón G, López M, González N, De Leo C, Castelán N, Bordes J, Alarcón-Segovia D, Granados J, Ramírez E, Lisker R.
PMID: 28561491
Am J Hum Biol. 1997;9(1):1-5. doi: 10.1002/(SICI)1520-6300(1997)9:1<1::AID-AJHB1>3.0.CO;2-5.

The aim of the present study was to evaluate the frequency of HLA-A and HLA-B antigens in a sample of the Mexico City Mestizo population. Previous similar studies were done by other authors in nonrelated individuals, while the present...

Measles Virus Epitope Presentation by HLA: Novel Insights into Epitope Selection, Dominance, and Microvariation.

Frontiers in immunology

Schellens IM, Meiring HD, Hoof I, Spijkers SN, Poelen MC, van Gaans-van den Brink JA, Costa AI, Vennema H, Keşmir C, van Baarle D, van Els CA.
PMID: 26579122
Front Immunol. 2015 Nov 02;6:546. doi: 10.3389/fimmu.2015.00546. eCollection 2015.

Immunity to infections with measles virus (MV) can involve vigorous human leukocyte antigen (HLA) class I-restricted CD8(+) cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome. To address which...

Identification of five novel HLA-B alleles in donors from the Colombian Bone Marrow Donor Registry.

HLA

Hernández DG, Camacho Ramírez N, Mosquera Martínez M, Cendales PA, Camacho BA.
PMID: 34931486
HLA. 2021 Dec 20; doi: 10.1111/tan.14516. Epub 2021 Dec 20.

Identification of five novel HLA-B alleles in five samples from Colombian bone marrow donors.

Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B*58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions.

Allergy, asthma & immunology research

Nguyen DV, Vida C, Chu HC, Fulton R, Li J, Fernando SL.
PMID: 27826965
Allergy Asthma Immunol Res. 2017 Jan;9(1):79-84. doi: 10.4168/aair.2017.9.1.79.

The HLA B*58:01 allele has been worldwide reported as a pharmacogenetic susceptibility to allopurinol-induced severe cutaneous adverse reactions (SCARs). To prevent these life-threatening conditions, the American College of Rheumatology hingly recommended that the HLA-B*58:01 be screened prior to the...

Showing 1 to 10 of 10 entries