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Showing 1 to 12 of 394 entries
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The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients

adult

[No authors listed]
GSID: NwmNbGHcuccJ
J Gibney, JD Wallace, T Spinks… - The Journal of …, 1999 - academic.oup.com

… The long term effects of GH replacement in adult GH-deficient … IN RECENT years the condition of adult GH deficiency (GHD… In this study we report on a cohort of 21 patients with adult …

Unexpected effects of the MIP-CreER transgene and tamoxifen on β-cell growth in C57Bl6/J male mice.

Physiological reports

Carboneau BA, Le TD, Dunn JC, Gannon M.
PMID: 27670405
Physiol Rep. 2016 Sep;4(18). doi: 10.14814/phy2.12863.

Transgenic mouse models have been fundamental in the discovery of factors that regulate β-cell development, mass, and function. Several groups have recently shown that some of these models display previously uncharacterized phenotypes due to the transgenic system itself. These...

Role of abnormal anterior pituitary hormones-growth hormone and prolactin in active systemic lupus erythematosus.

International journal of clinical and experimental medicine

Zhu X, Xu J, Li S, Huang W, Li F.
PMID: 26770558
Int J Clin Exp Med. 2015 Oct 15;8(10):19223-31. eCollection 2015.

BACKGROUND: The role of anterior pituitary hormones in systemic lupus erythematosus (SLE) remains controversial.AIMS AND OBJECTIVES: We determined the expression levels of human growth hormone (GH), prolactin (PRL), and their receptors in subjects presenting with SLE, and modulation of...

A randomized controlled trial to compare the effects of liquid versus powdered recombinant human growth hormone in treating patients with severe burns.

Biomedical reports

Chen G, Shao H, Pan X.
PMID: 27123246
Biomed Rep. 2016 May;4(5):551-556. doi: 10.3892/br.2016.635. Epub 2016 Mar 22.

Recombinant human growth hormone (rhGH) promotes protein utilization and synthesis, and is widely used as a therapy to treat severe burns. The present randomized controlled trial evaluated the effects of different forms of rhGH on patients with severe burns....

Exploiting Nanobodies in the Detection and Quantification of Human Growth Hormone .

Frontiers in endocrinology

Murad H, Assaad JM, Al-Shemali R, Abbady AQ.
PMID: 28611730
Front Endocrinol (Lausanne). 2017 May 30;8:115. doi: 10.3389/fendo.2017.00115. eCollection 2017.

BACKGROUND: Monitoring blood levels of human growth hormone (hGH) in most children with short stature deficiencies is crucial for taking a decision of treatment with extended course of daily and expensive doses of recombinant hGH (rhGH or SomatropinMETHODS: A...

Patients' perceptions on the usability of the SurePal™ self-injection device for Omnitrope.

Therapeutic advances in endocrinology and metabolism

Coutant R, Dupuis C, Pigeon P, Rebaud P.
PMID: 29051812
Ther Adv Endocrinol Metab. 2017 Sep;8(9):129-137. doi: 10.1177/2042018817730545. Epub 2017 Oct 02.

BACKGROUND: A questionnaire-based survey was conducted to evaluate attitudes towards a reusable self-injection system, SurePal™, among paediatric patients with growth disturbances who were prescribed treatment with somatropin (OmnitropeMETHODS: This cross-sectional survey was incorporated into the multinational, multi-centre, noninterventional PAtients...

Human Growth Hormone in Sports: No.

The Physician and sportsmedicine

Murray TH.
PMID: 27442926
Phys Sportsmed. 1986 May;14(5):29. doi: 10.1080/00913847.1986.11709063.

No abstract available.

Human Growth Hormone: The Latest Ergogenic Aid?.

The Physician and sportsmedicine

Cowart VS.
PMID: 27404836
Phys Sportsmed. 1988 Mar;16(3):175-85. doi: 10.1080/00913847.1988.11709462.

The supply of human growth hormone now available to athletes seems small and costly, but drug testing experts agree that abuse of the substance could become a serious problem, especially if synthetic hormone becomes more widely available.

Effect of Amino Acids on Growth Hormone Release.

The Physician and sportsmedicine

Jacobson BH.
PMID: 27437804
Phys Sportsmed. 1990 Jan;18(1):63-70. doi: 10.1080/00913847.1990.11709950.

In brief: The contention that amino acids increase secretion of human growth hormone has served as the catalyst for their increased popularity. Although growth hormone has been linked to muscle hypertrophy and its secretion is known to increase with...

The effect of topically applied recombinant human growth hormone on wound healing in pigs.

Wounds : a compendium of clinical research and practice

Kim SH, Heo EJ, Lee SW.
PMID: 25903440
Wounds. 2009 Jun;21(6):158-63.

The beneficial wound healing effect of the systemic growth hormone (GH) mediated by insulin-like growth factor 1 (IGF-1) has been widely reported. Recent studies have suggested that GH facilitates wound healing not by circulating IGF-1, but by local IGF-1...

A randomized pilot trial of growth hormone with anastrozole versus growth hormone alone, starting at the very end of puberty in adolescents with idiopathic short stature.

International journal of pediatric endocrinology

Rothenbuhler A, Linglart A, Bougnères P.
PMID: 25972902
Int J Pediatr Endocrinol. 2015;2015(1):4. doi: 10.1186/1687-9856-2015-4. Epub 2015 Feb 16.

BACKGROUND: When given during the course of puberty, anastrozole (A), an aromatase inhibitor, has been shown to increase the predicted adult height (PAH) of GH-deficient (GHD) boys treated with recombinant human growth hormone (rhGH). Our study questioned whether this...

Vascular Applications of Human Gene Therapy.

Journal of thrombosis and thrombolysis

Pickering JG, Takeshita S, Feldman L, Losordo DW, Isner JM.
PMID: 10608008
J Thromb Thrombolysis. 1995;1(3):299-302. doi: 10.1007/BF01060740.

Complexing recombinant DNA with cationic liposomes is a convenient means of introducing foreign genes into cells (lipofection) and could potentially form the basis for genetically modifying diseased blood vessels in patients. The mechanism of lipofection is incompletely understood, but...

Showing 1 to 12 of 394 entries