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Showing 1 to 12 of 394 entries
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Safety of rhGH, Early vs Late: the Hare Seems Fine, but What About the Tortoise?.

The Journal of clinical endocrinology and metabolism

Rogol AD.
PMID: 34963134
J Clin Endocrinol Metab. 2021 May 13;106(6):e2450-e2451. doi: 10.1210/clinem/dgab116.

No abstract available.

Outcomes in children treated with growth hormone for Prader-Willi syndrome: data from the ANSWER Program® and NordiNet® International Outcome Study.

International journal of pediatric endocrinology

Angulo M, Abuzzahab MJ, Pietropoli A, Ostrow V, Kelepouris N, Tauber M.
PMID: 33292530
Int J Pediatr Endocrinol. 2020 Nov 10;2020(1):20. doi: 10.1186/s13633-020-00090-6.

BACKGROUND: Growth hormone (GH) deficiency is common in patients with Prader-Willi syndrome (PWS) and leads to short adult stature. The current study assessed clinical outcomes based on real-world observational data in pediatric patients with PWS who were treated with...

Height outcomes in children with growth hormone deficiency and idiopathic short stature treated concomitantly with growth hormone and aromatase inhibitor therapy: data from the ANSWER program.

International journal of pediatric endocrinology

Miller BS, Ross J, Ostrow V.
PMID: 33042202
Int J Pediatr Endocrinol. 2020;2020:19. doi: 10.1186/s13633-020-00089-z. Epub 2020 Oct 06.

BACKGROUND: Treatment of children with growth hormone deficiency (GHD) or idiopathic short stature (ISS) using GH is only effective for bone growth prior to epiphyseal fusion. Aromatase inhibitor therapy (AIT) blocks estrogen production, thereby delaying epiphyseal fusion. The current...

[Growth hormone deficit: Influence of puberty on the response to treatment].

Anales de pediatria

Sánchez Malo MJ, Hidalgo Sanz J, Hernández Tejedor C, García Ventura M, Ferrer Lozano M, Labarta Aizpún JI, de Arriba Muñoz A.
PMID: 33994327
An Pediatr (Engl Ed). 2021 May 13; doi: 10.1016/j.anpedi.2021.04.003. Epub 2021 May 13.

INTRODUCTION: Short stature is the most frequent reason for consultation in Pediatric Endocrinology consultations and sometimes requires treatment with growth hormone. The aim of the study was to analyze the response to treatment based on its onset in pubertal...

Homicidality and Psychosis Caused by an Over-the-Counter Performance-Enhancing Supplement Containing Dendrobium Extract and L-Dopa.

P & T : a peer-reviewed journal for formulary management

Flynn A, Lincoln J, Burke M.
PMID: 27313436
P T. 2016 Jun;41(6):381-4.

The authors examine the role that unregulated dietary supplements may have had in a young man who presented with psychotic and homicidal ideations.


Acta endocrinologica (Bucharest, Romania : 2005)

Kör Y, Keskin M.
PMID: 31149129
Acta Endocrinol (Buchar). 2016 Oct-Dec;12(4):443-449. doi: 10.4183/aeb.2016.443.

BACKGROUND/AIMS: Growth hormone (GH) treatment has severe cost burden on patients, their families, and healthcare systems. Therefore, accuracy of diagnosis should be confirmed; factors affecting the response to treatment should be defined. The present study is performed to evaluate...

Sleep deprivation and diet affect human GH gene expression in transgenic mice in vivo.

Endocrine connections

Jarmasz JS, Jin Y, Vakili H, Cattini PA.
PMID: 33112821
Endocr Connect. 2020 Dec;9(12):1135-1147. doi: 10.1530/EC-20-0354.

Human (h) growth hormone (GH) production studies are largely limited to effects on secretion. How pituitary hGH gene (hGH-N/GH1) expression is regulated is important in our understanding of the role hGH plays in physiology and disease. Here we assess...

Noonan syndrome and Turner syndrome patients respond similarly to 4 years' growth-hormone therapy: longitudinal analysis of growth-hormone-naïve patients enrolled in the NordiNet® International Outcome Study and the ANSWER Program.

International journal of pediatric endocrinology

Lee PA, Ross JL, Pedersen BT, Kotnik P, Germak JA, Christesen HT.
PMID: 26351466
Int J Pediatr Endocrinol. 2015;2015(1):17. doi: 10.1186/s13633-015-0015-1. Epub 2015 Sep 08.

BACKGROUND: Turner syndrome (TS) and Noonan syndrome (NS) are distinct syndromes associated with short stature and other similar phenotypic features. We compared the responses to growth hormone (GH) therapy of TS and NS patients enrolled in the NordiNet® International...

Pregnancy outcomes in women receiving growth hormone replacement therapy enrolled in the NordiNet® International Outcome Study (IOS) and the American Norditropin® Studies: Web-Enabled Research (ANSWER) Program.


Biller BMK, Höybye C, Carroll P, Gordon MB, Birkegård AC, Kelepouris N, Nedjatian N, Weber MM.
PMID: 33709288
Pituitary. 2021 Aug;24(4):611-621. doi: 10.1007/s11102-021-01138-3. Epub 2021 Mar 12.

PURPOSE: Data on the safety of growth hormone (GH) replacement therapy during pregnancy are limited. We report a combined analysis of data from pregnant women treated with GH while enrolled in two non-interventional, multicenter studies: NordiNet® International Outcome Study...

Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism.

Frontiers in veterinary science

Načeradská M, Návojová Horáčková K, Fridrichová M.
PMID: 34881322
Front Vet Sci. 2021 Nov 22;8:773355. doi: 10.3389/fvets.2021.773355. eCollection 2021.

A 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and

Acceptance of a reusable self-injection device for recombinant human growth hormone: final data from a questionnaire-based, cross-sectional, international, multicenter, observational study in pediatric patients.

Medical devices (Auckland, N.Z.)

Schnabel D, Partsch CJ, Houang M, Ehtisham S, Johnstone H, Zabransky M, Kiess W.
PMID: 27660496
Med Devices (Auckl). 2016 Sep 07;9:317-24. doi: 10.2147/MDER.S115933. eCollection 2016.

BACKGROUND: A questionnaire-based survey was conducted to assess attitudes toward a reusable self-injection system (SurePal™) among pediatric patients with growth disturbances who were prescribed treatment with Omnitrope(®) within routine clinical practice.METHODS: This was a multicenter, observational study, incorporated into...

Recombinant human growth hormone improves the immune status of rats with septic encephalopathy: The role of VEGFR2 in the prevalence of endoplasmic reticulum stress repair module.

International immunopharmacology

Zaky DA, Eldehna WM, El Kerdawy AM, Abdallah DM, El Abhar HS, Wadie W.
PMID: 34794887
Int Immunopharmacol. 2021 Dec;101:108370. doi: 10.1016/j.intimp.2021.108370. Epub 2021 Nov 15.

Septic encephalopathy results from the intense reaction of the immune system to infection. The role of growth hormone (GH) signaling in maintaining brain function is well established; however, the involvement of the vascular endothelial growth factor receptor-2 (VEGFR2) in...

Showing 1 to 12 of 394 entries