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Showing 1 to 12 of 32 entries
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Inhibin A/B in HMG or recombinant FSH ovarian stimulation with cetrorelix medication.

Reproductive biomedicine online

Engel JB, Felberbaum RE, Reissmann T, Kose R, Diedrich K.
PMID: 12513871
Reprod Biomed Online. 2001;3(2):104-108. doi: 10.1016/s1472-6483(10)61976-1.

The inhibins are valuable factors in the assessment of the quality of an ovarian stimulation cycle. In spite of good clinical results with recombinant FSH and multiple dose LHRH- antagonist (Cetrotide((R))) administration, there remains a theoretical concern that in...

Inhibin and activin Molecular aspects of regulation and function.

Trends in endocrinology and metabolism: TEM

Mayo KE.
PMID: 18407237
Trends Endocrinol Metab. 1994 Dec;5(10):407-15. doi: 10.1016/1043-2760(95)92523-l.

Inhibins and activins exhibit a broad spectrum of biologic activities, many of which affect the reproductive axis. Within the ovary and testis, the synthesis of the inhibin and activin alpha and beta subunits is regulated by circulating hormones, such...

Serum biomarkers for predicting pregnancy outcome in women undergoing IVF: human chorionic gonadotropin, progesterone, and inhibin A level at 11 days post-ET.

Clinical and experimental reproductive medicine

Kim JH, Shin MS, Yi G, Jee BC, Lee JR, Suh CS, Kim SH.
PMID: 22563548
Clin Exp Reprod Med. 2012 Mar;39(1):28-32. doi: 10.5653/cerm.2012.39.1.28. Epub 2012 Mar 31.

OBJECTIVE: This study was performed to assess the prognostic value of serum hCG, progesterone, and inhibin A levels measured at 11 days post-ET for predicting pregnancy outcome in women participating in IVF.METHODS: Between May 2005 and April 2008, sera...

The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models.

Journal of skin cancer

Glick AB.
PMID: 23326666
J Skin Cancer. 2012;2012:249063. doi: 10.1155/2012/249063. Epub 2012 Dec 26.

TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells, extracellular matrix production, angiogenesis,...

Alterations in plasma and ovarian immunoreactive inhibin during reproductive aging in the female rat.

Endocrine

Jih MH, Wu TC.
PMID: 21153184
Endocrine. 1995 May;3(5):327-33. doi: 10.1007/BF03021415.

Previously, we showed that ovarian inhibin α- and β;(A)-subunit mRNAs are elevated in middle-aged and old persistent-estrous (PE) female rats. To determine whether higher inhibin subunit mRNA expressions result in increased circulating inhibins during reproductive aging, plasma immunoreactive inhibin...

Curative GnRHa treatment has an unexpected repressive effect on Sertoli cell specific genes.

Basic and clinical andrology

Gegenschatz-Schmid K, Verkauskas G, Demougin P, Bilius V, Dasevicius D, Stadler MB, Hadziselimovic F.
PMID: 29456864
Basic Clin Androl. 2018 Feb 09;28:2. doi: 10.1186/s12610-018-0067-1. eCollection 2018.

BACKGROUND: Follicle stimulating hormone and testosterone stimulate Sertoli cells to support germ cell function and differentiation. During mini-puberty, when gonadotropin (GnRH) stimulates increases in plasma luteinizing hormone (LH) and testosterone levels, gonocytes are transformed into Ad spermatogonia. In cryptorchidism,...

Identification of Novel Nucleotide Changes in INHBB Gene by Mutation Screening in Females with Ovarian Dysgenesis: A Case Report.

Journal of reproduction & infertility

Chauhan P, Rani A, Rai AK.
PMID: 34987992
J Reprod Infertil. 2021 Oct-Dec;22(4):295-301. doi: 10.18502/jri.v22i4.7656.

BACKGROUND: Inhibin and activin regulate the follicle stimulating hormone level by their antagonistic actions and thus have been considered as strong candidate genes in the etiology of ovarian dysgenesis. In the present study, two cases of primary amenorrhea with...

Serum and urine profiles of TGF-β superfamily members in reproductive aged women.

Clinica chimica acta; international journal of clinical chemistry

Calvert ME, Kalra B, Patel A, Kumar A, Shaw ND.
PMID: 34875272
Clin Chim Acta. 2021 Dec 05;524:96-100. doi: 10.1016/j.cca.2021.12.002. Epub 2021 Dec 05.

BACKGROUND: TGF-β superfamily members are important biomarkers of reproductive health in women desiring fertility and during pregnancy. TGF-β proteins derived from the ovary and/or placenta have been detected in serum in women, but there have been very few attempts...

Ovarian Aging: Role of Pituitary-Ovarian Axis Hormones and ncRNAs in Regulating Ovarian Mitochondrial Activity.

Frontiers in endocrinology

Colella M, Cuomo D, Peluso T, Falanga I, Mallardo M, De Felice M, Ambrosino C.
PMID: 34975760
Front Endocrinol (Lausanne). 2021 Dec 16;12:791071. doi: 10.3389/fendo.2021.791071. eCollection 2021.

The number of mitochondria in the oocyte along with their functions (e.g., energy production, scavenger activity) decline with age progression. Such multifaceted functions support several processes during oocyte maturation, ranging from energy supply to synthesis of the steroid hormones....

The role of inhibin in polycystic ovary syndrome.

Human fertility (Cambridge, England)

Lockwood GM.
PMID: 11844360
Hum Fertil (Camb). 2000;3(2):86-92. doi: 10.1080/1464727002000198751.

Polycystic ovary syndrome (PCOS) is a common heterogeneous disorder which, in its severest manifestations, is associated with anovulation, hyperandrogenism and metabolic imbalance. The biochemical markers for the condition can include a significantly raised LH:FSH ratio and a raised testosterone...

From Consternation to Revelation: Discovery of a Role for IGSF1 in Pituitary Control of Thyroid Function.

Journal of the Endocrine Society

Bernard DJ, Brûlé E, Smith CL, Joustra SD, Wit JM.
PMID: 29594256
J Endocr Soc. 2018 Feb 06;2(3):220-231. doi: 10.1210/js.2017-00478. eCollection 2018 Mar 01.

Immunoglobulin superfamily, member 1 (IGSF1) is a transmembrane glycoprotein highly expressed in the mammalian pituitary gland. Shortly after its discovery in 1998, the protein was proposed to function as a coreceptor for inhibins (and was even temporarily renamed inhibin...

Serum and urine profiles of TGF-β superfamily members in reproductive aged women.

Clinica chimica acta; international journal of clinical chemistry

Calvert ME, Kalra B, Patel A, Kumar A, Shaw ND.
PMID: 34875272
Clin Chim Acta. 2021 Dec 05;524:96-100. doi: 10.1016/j.cca.2021.12.002. Epub 2021 Dec 05.

BACKGROUND: TGF-β superfamily members are important biomarkers of reproductive health in women desiring fertility and during pregnancy. TGF-β proteins derived from the ovary and/or placenta have been detected in serum in women, but there have been very few attempts...

Showing 1 to 12 of 32 entries