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Showing 1 to 12 of 2065 entries
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The interleukin‐1 genotype as a severity factor in adult periodontal disease

adult

Kornman KS.
GSID: pMm2_FkADiYJ
KS Kornman, A Crane, HY Wang… - Journal of clinical …, 1997 - Wiley Online Library

… Periodontitis involves multiple clinical patterns including various severities of adult periodontitis. … adult periodontitis_ has been reported to affect over 30% of the adult population. with …

The role of serum cytokines in the pathogenesis of hepatic osteodystrophy in male cirrhotic patients.

Gastroenterology research and practice

Soylu AR, Tuglu C, Arikan E, Yetisyigit T, Kunduracılar H, Koker IH, Unsal G, Tezel AH, Umit H, Berkarda S.
PMID: 23097664
Gastroenterol Res Pract. 2012;2012:425079. doi: 10.1155/2012/425079. Epub 2012 Oct 14.

Objective. In this study, we aimed to investigate the possible role of serum cytokines in the development of hepatic osteodystrophy. Matherial and Methods. 44 consecutive male cirrhotic patients (17 alcoholic, 20 hepatitis B, 7 hepatitis C), 15 age- and...

The Role of Interleukin-1 Genotype in the Association between Coronary Heart Disease and Periodontitis in a Syrian Population.

ISRN dentistry

Bashour L, Khattab R, Harfoush E.
PMID: 23691333
ISRN Dent. 2013 Apr 14;2013:195678. doi: 10.1155/2013/195678. Print 2013.

Objective. To determine whether differences exist between periodontitis subjects with and without Coronary Heart Disease (CHD) in a Syrian population in the distribution of IL-1 alleles at positions IL-1α+4845, IL-1β+3954, IL-1β-511, and IL-1RN VNTR. Background. The role of Interleukin-1...

Effect of serum interleukin-1 receptor antagonist level on survival of patients with non-small cell lung cancer.

Molecular and clinical oncology

Yigit M, Değirmencioğlu S, Ugurlu E, Yaren A.
PMID: 28515924
Mol Clin Oncol. 2017 May;6(5):708-712. doi: 10.3892/mco.2017.1195. Epub 2017 Mar 15.

Due to poor prognosis in advanced non-small cell lung cancer (NSCLC), new effective markers are required in the monitoring of the disease. The present study aimed to investigate the association between the serum IL-1 receptor antagonist (IL-1Ra) level, overall...

Intra-articular interleukin-1 receptor antagonist (IL1-ra) microspheres for posttraumatic osteoarthritis: in vitro biological activity and in vivo disease modifying effect.

Journal of experimental orthopaedics

Elsaid KA, Ubhe A, Shaman Z, D'Souza G.
PMID: 27539076
J Exp Orthop. 2016 Dec;3(1):18. doi: 10.1186/s40634-016-0054-4. Epub 2016 Aug 19.

BACKGROUND: Interleukin-1 receptor antagonist (IL-1 ra) can be disease-modifying in posttraumatic osteoarthritis (PTOA). One limitation is its short joint residence time. We hypothesized that IL-1 ra encapsulation in poly (lactide-co-glycolide) (PLGA) microspheres reduces IL-1 ra systemic absorption and provides...

The Use of IL-1 Receptor Antagonist (Anakinra) in Idiopathic Recurrent Pericarditis: A Narrative Review.

Cardiology research and practice

Baskar S, Klein AL, Zeft A.
PMID: 26942035
Cardiol Res Pract. 2016;2016:7840724. doi: 10.1155/2016/7840724. Epub 2016 Jan 31.

Recurrent pericarditis is a complication of acute pericarditis in 20-30% of the patients and is usually idiopathic in nature. The underlying pathogenesis of this condition remains unclear, although immune-mediated mechanisms seem likely. A subgroup of these patients with refractory...

A case of cryopyrin-associated periodic syndrome with kidney transplant failure.

CEN case reports

Imaizumi R, Ishii Y, Miki K, Kudo S, Murakami T, Koyama I, Nakajima I, Fuchinoue S, Kawaguchi Y, Taniguchi A, Teraoka S.
PMID: 28509262
CEN Case Rep. 2015 May;4(1):1-5. doi: 10.1007/s13730-014-0129-y. Epub 2014 Jun 14.

The cryopyrin-associated periodic syndrome (CAPS) is an autosomal dominant autoinflammatory disease characterized by fever, skin rash, and joint involvement with acute inflammatory response. The genetic defect involves the NLRP3 gene that encodes cryopyrin and leads to an abnormal production...

Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.

World journal of hepatology

Reiter FP, Wimmer R, Wottke L, Artmann R, Nagel JM, Carranza MO, Mayr D, Rust C, Fickert P, Trauner M, Gerbes AL, Hohenester S, Denk GU.
PMID: 27004088
World J Hepatol. 2016 Mar 18;8(8):401-10. doi: 10.4254/wjh.v8.i8.401.

AIM: To study the interleukin-1 (IL-1) pathway as a therapeutic target for liver fibrosis in vitro and in vivo using the ATP-binding cassette transporter b4(-/-) (Abcb4(-/-)) mouse model.METHODS: Female and male Abcb4(-/-) mice from 6 to 13 mo of...

Efficacy of Trigonella foenum-graecum Seed Extract in Reducing Metabolic and Inflammatory Alterations Associated With Menopause.

Iranian Red Crescent medical journal

Abedinzade M, Nasri S, Jamal Omodi M, Ghasemi E, Ghorbani A.
PMID: 26732240
Iran Red Crescent Med J. 2015 Nov 16;17(11):e26685. doi: 10.5812/ircmj.26685. eCollection 2015 Nov.

BACKGROUND: Several experimental and clinical studies support beneficial effects of Trigonella foenum-graecum (fenugreek) in the management of metabolic diseases and inflammatory disorders.OBJECTIVES: The purpose of this study was to examine the effect of T. foenum-graecum seed extract in reducing...

Genes Involved in Interleukin-1 Receptor Type II Activities Are Associated With Asthmatic Phenotypes.

Allergy, asthma & immunology research

Madore AM, Vaillancourt VT, Bouzigon E, Sarnowski C, Monier F, Dizier MH, Demenais F, Laprise C.
PMID: 27334786
Allergy Asthma Immunol Res. 2016 Sep;8(5):466-70. doi: 10.4168/aair.2016.8.5.466.

PURPOSE: Interleukin-1 (IL-1) plays a key role in inflammation and immunity and its decoy receptor, IL-1R2, has been implicated in transcriptomic and genetic studies of asthma.METHODS: Two large asthma family collections, the French-Canadian Saguenay-Lac-St-Jean (SLSJ) study and the French...

Interleukin-1 receptor antagonist inhibits angiogenesis via blockage IL-1α/PI3K/NF-κβ pathway in human colon cancer cell.

Cancer management and research

Ma J, Sun X, Guo T, Su H, Chen Q, Gong Z, Qi J, Zhao X.
PMID: 29062241
Cancer Manag Res. 2017 Oct 09;9:481-493. doi: 10.2147/CMAR.S147699. eCollection 2017.

PURPOSE: This article investigates the relationship between cancer cells and stromal cells in carcinoma cell living microenvironment and elucidates the mechanism that interleukin-1 receptor antagonist (IL-1RA) blocks metastatic potential in colon cancer.METHODS: Western blot and RT-PCR assay were used...

Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer.

Frontiers in pharmacology

Armbruster N, Krieg J, Weißenberger M, Scheller C, Steinert AF.
PMID: 28536528
Front Pharmacol. 2017 May 09;8:255. doi: 10.3389/fphar.2017.00255. eCollection 2017.

No abstract available.

Showing 1 to 12 of 2065 entries