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Showing 1 to 10 of 10 entries
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Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis.

BMJ (Clinical research ed.)

Virtanen M, Nyberg ST, Batty GD, Jokela M, Heikkilä K, Fransson EI, Alfredsson L, Bjorner JB, Borritz M, Burr H, Casini A, Clays E, De Bacquer D, Dragano N, Elovainio M, Erbel R, Ferrie JE, Hamer M, Jöckel KH, Kittel F, Knutsson A, Koskenvuo M, Koskinen A, Lunau T, Madsen IE, Nielsen ML, Nordin M, Oksanen T, Pahkin K, Pejtersen JH, Pentti J, Rugulies R, Salo P, Shipley MJ, Siegrist J, Steptoe A, Suominen SB, Theorell T, Toppinen-Tanner S, Väänänen A, Vahtera J, Westerholm PJ, Westerlund H, Slopen N, Kawachi I, Singh-Manoux A, Kivimäki M.
PMID: 23929894
BMJ. 2013 Aug 08;347:f4746. doi: 10.1136/bmj.f4746.

OBJECTIVE: To determine the association between self reported job insecurity and incident coronary heart disease.DESIGN: A meta-analysis combining individual level data from a collaborative consortium and published studies identified by a systematic review.DATA SOURCES: We obtained individual level data...

Associations between Mobility, Cognition, and Brain Structure in Healthy Older Adults.

Frontiers in aging neuroscience

Demnitz N, Zsoldos E, Mahmood A, Mackay CE, Kivimäki M, Singh-Manoux A, Dawes H, Johansen-Berg H, Ebmeier KP, Sexton CE.
PMID: 28588477
Front Aging Neurosci. 2017 May 23;9:155. doi: 10.3389/fnagi.2017.00155. eCollection 2017.

Mobility limitations lead to a cascade of adverse events in old age, yet the neural and cognitive correlates of mobility performance in older adults remain poorly understood. In a sample of 387 adults (mean age 69.0 ± 5.1 years),...

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.

BioData mining

Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, Riess H, Sivapalaratnam S, Tragante V, van Iperen EPA, Brautbar A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Larson EB, Rasmussen-Torvik LJ, Tromp G, Baumert J, Cruickshanks KJ, Farrall M, Hingorani AD, Hovingh GK, Kleber ME, Klein BE, Klein R, Koenig W, Lange LA, Mӓrz W, North KE, Charlotte Onland-Moret N, Reiner AP, Talmud PJ, van der Schouw YT, Wilson JG, Kivimaki M, Kumari M, Moore JH, Drenos F, Asselbergs FW, Keating BJ, Ritchie MD.
PMID: 28770004
BioData Min. 2017 Jul 24;10:25. doi: 10.1186/s13040-017-0145-5. eCollection 2017.

BACKGROUND: The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol...

Association Between Systemic Inflammation and Individual Symptoms of Depression: A Pooled Analysis of 15 Population-Based Cohort Studies.

The American journal of psychiatry

Frank P, Jokela M, Batty GD, Cadar D, Steptoe A, Kivimäki M.
PMID: 34645276
Am J Psychiatry. 2021 Dec;178(12):1107-1118. doi: 10.1176/appi.ajp.2021.20121776. Epub 2021 Oct 14.

OBJECTIVE: Evidence from anti-inflammatory drug trials for the treatment of depression has been inconsistent. This may be ascribed to the differing symptom-specific effects of inflammation. Accordingly, the authors explored the associations between systemic inflammation and an array of individual...

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.

BioData mining

Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, Riess H, Sivapalaratnam S, Tragante V, van Iperen EPA, Brautbar A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Larson EB, Rasmussen-Torvik LJ, Tromp G, Baumert J, Cruickshanks KJ, Farrall M, Hingorani AD, Hovingh GK, Kleber ME, Klein BE, Klein R, Koenig W, Lange LA, Mӓrz W, North KE, Charlotte Onland-Moret N, Reiner AP, Talmud PJ, van der Schouw YT, Wilson JG, Kivimaki M, Kumari M, Moore JH, Drenos F, Asselbergs FW, Keating BJ, Ritchie MD.
PMID: 28770004
BioData Min. 2017 Jul 24;10:25. doi: 10.1186/s13040-017-0145-5. eCollection 2017.

BACKGROUND: The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol...

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.

BioData mining

Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, Riess H, Sivapalaratnam S, Tragante V, van Iperen EPA, Brautbar A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Larson EB, Rasmussen-Torvik LJ, Tromp G, Baumert J, Cruickshanks KJ, Farrall M, Hingorani AD, Hovingh GK, Kleber ME, Klein BE, Klein R, Koenig W, Lange LA, Mӓrz W, North KE, Charlotte Onland-Moret N, Reiner AP, Talmud PJ, van der Schouw YT, Wilson JG, Kivimaki M, Kumari M, Moore JH, Drenos F, Asselbergs FW, Keating BJ, Ritchie MD.
PMID: 28770004
BioData Min. 2017 Jul 24;10:25. doi: 10.1186/s13040-017-0145-5. eCollection 2017.

BACKGROUND: The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol...

Physical activity and peripheral artery disease: Two prospective cohort studies and a systematic review.

Atherosclerosis

Heikkilä K, Coughlin PA, Pentti J, Kivimäki M, Halonen JI.
PMID: 31136912
Atherosclerosis. 2019 Jul;286:114-120. doi: 10.1016/j.atherosclerosis.2019.05.008. Epub 2019 May 10.

BACKGROUND AND AIMS: Physical activity is a modifiable risk factor for cardiovascular disease and an important therapy in individuals with intermittent claudication. However, its role in the development of peripheral artery disease (PAD) is unclear. We have examined the...

Adverse childhood experiences and incident coronary heart disease: a counterfactual analysis in the Whitehall II prospective cohort study.

American journal of preventive cardiology

Akasaki M, Nicholas O, Abell J, Valencia-Hernández CA, Hardy R, Steptoe A.
PMID: 34611646
Am J Prev Cardiol. 2021 Jun 24;7:100220. doi: 10.1016/j.ajpc.2021.100220. eCollection 2021 Sep.

OBJECTIVES: Adverse childhood experience is thought to be associated with risk of coronary heart disease, but it is not clear which experiences are cardiotoxic, and whether risk increases with the accumulation of adverse childhood experiences.METHODS: Participants were 5149 adults...

Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory.

International journal of obesity (2005)

Brunner EJ, Maruyama K, Shipley M, Cable N, Iso H, Hiyoshi A, Stallone D, Kumari M, Tabak A, Singh-Manoux A, Wilson J, Langenberg C, Wareham N, Boniface D, Hingorani A, Kivimäki M, Llewellyn C.
PMID: 33446837
Int J Obes (Lond). 2021 Apr;45(4):758-765. doi: 10.1038/s41366-020-00735-9. Epub 2021 Jan 14.

BACKGROUND/OBJECTIVES: The mediating role of eating behaviors in genetic susceptibility to weight gain during mid-adult life is not fully understood. This longitudinal study aims to help us understand contributions of genetic susceptibility and appetite to weight gain.SUBJECTS/METHODS: We followed...

Structural social relations and cognitive ageing trajectories: evidence from the Whitehall II cohort study.

International journal of epidemiology

Elovainio M, Sommerlad A, Hakulinen C, Pulkki-Råback L, Virtanen M, Kivimäki M, Singh-Manoux A.
PMID: 29121238
Int J Epidemiol. 2018 Jun 01;47(3):701-708. doi: 10.1093/ije/dyx209.

BACKGROUND: Social relations are important for health, particularly at older ages. We examined the salience of frequency of social contacts and marital status for cognitive ageing trajectories over 21 years, from midlife to early old age.METHODS: Data are from...

Showing 1 to 10 of 10 entries