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Proteomics on Fixed Tissue Specimens - A Review.

Current proteomics

Reimel BA, Pan S, May DH, Shaffer SA, Goodlett DR, McIntosh MW, Yerian LM, Bronner MP, Chen R, Brentnall TA.
PMID: 19829741
Curr Proteomics. 2009 Apr 01;6(1):63-69. doi: 10.2174/157016409787847420.

The vast majority of clinical tissue samples are formalin-fixed and paraffin-preserved. This type of preservation has been considered an obstacle to protein extraction from these tissues. However, these are the very tissue samples that have associated patient histories, diagnoses...

Proteomics studies of pancreatic cancer.

Proteomics. Clinical applications

Chen R, Pan S, Aebersold R, Brentnall TA.
PMID: 18633454
Proteomics Clin Appl. 2007;1(12):1582-1591. doi: 10.1002/prca.200700414.

Pancreatic cancer is the fourth leading cause of cancer death in the United States, with 4% survival 5 years after diagnosis. Biomarkers are desperately needed to improve earlier, more curable cancer diagnosis and to develop new effective therapeutic targets....

Showing 1 to 2 of 2 entries