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Showing 1 to 12 of 244 entries
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Expression of e-cadherin, leukemia inhibitory factor and progesterone receptor in mouse blastocysts after ovarian stimulation.

Cell journal

Movaghar B, Askarian S.
PMID: 23508459
Cell J. 2012;14(3):225-30. Epub 2012 Dec 12.

OBJECTIVE: The appropriate interaction between a blastocyst and the endometrium is essential for successful implantation. Numerous factors, including hormone receptors (progesterone receptor), cytokines [leukemia inhibitory factors (LIF)], and adherence molecules such as E-cadherin are involved in the cross-talk that...

Culture conditions for bovine embryonic stem cell-like cells isolated from blastocysts after external fertilization.

Cytotechnology

Jin M, Wu A, Dorzhin S, Yue Q, Ma Y, Liu D.
PMID: 22438181
Cytotechnology. 2012 Aug;64(4):379-89. doi: 10.1007/s10616-011-9408-z. Epub 2012 Mar 22.

Although isolation and characterization of embryonic stem cells have been successful in cattle, maintenance of bovine embryonic stem cells in culture remains difficult. In this study, we compared different methods of cell passaging, feeder cell layers and medium conditions...

Conserved Role of bFGF and a Divergent Role of LIF for Pluripotency Maintenance and Survival in Canine Pluripotent Stem Cells.

Stem cells and development

Luo J, Cibelli JB.
PMID: 27492281
Stem Cells Dev. 2016 Nov 01;25(21):1670-1680. doi: 10.1089/scd.2016.0164. Epub 2016 Sep 19.

Dogs have been widely used as a preclinical model for human disease. With the successful generation of canine induced pluripotent stem cells (ciPSCs), the biomedical community has a unique opportunity to study therapeutic interventions using autologous stem cells that...

Protective effect of resveratrol against light-induced retinal degeneration in aged SAMP8 mice.

Oncotarget

Liu Z, Wu Z, Li J, Marmalidou A, Zhang R, Yu M.
PMID: 29029471
Oncotarget. 2017 Jul 22;8(39):65778-65788. doi: 10.18632/oncotarget.19473. eCollection 2017 Sep 12.

PURPOSE: The purpose of this study was to determine the protective effects of Resveratrol (RESV) on acute bright light-induced retinal degeneration in aged senescence accelerated mouse strain.METHODS: Ten three-month-old male SAMP8 mice (prone to aging) were randomly assigned to...

Expression of leukemia inhibitory factor in craniopharyngioma.

Endocrine pathology

Tran A, Kovacs K, Stefaneanu L, Kontogeorgos G, Scheithauer BW, Melmed S.
PMID: 27519214
Endocr Pathol. 1999 Jun;10(2):103-8. doi: 10.1007/BF02739822.

It has recently been reported that overexpression of leukemia inhibitory factor (LIF) in mice transgenic for LIF causes invagination of the anterior wall of Rathke's pouch leading to the formation of cysts lined by LIF immunoreactive epithelial cells. Strong...

Simplified three-dimensional culture system for long-term expansion of embryonic stem cells.

World journal of stem cells

McKee C, Perez-Cruet M, Chavez F, Chaudhry GR.
PMID: 26328022
World J Stem Cells. 2015 Aug 26;7(7):1064-77. doi: 10.4252/wjsc.v7.i7.1064.

AIM: To devise a simplified and efficient method for long-term culture and maintenance of embryonic stem cells requiring less frequent passaging.METHODS: Mouse embryonic stem cells (ESCs) labeled with enhanced yellow fluorescent protein were cultured in three-dimensional (3-D) self-assembling scaffolds...

The regulation of leukemia inhibitory factor.

Cancer cell & microenvironment

Yue X, Wu L, Hu W.
PMID: 26807429
Cancer Cell Microenviron. 2015;2(3). doi: 10.14800/ccm.877.

Leukemia inhibitory factor (LIF), a secreted cytokine, plays an important role in a wide array of biological processes including inducing differentiation of leukemia cell, inflammatory response, neuronal development, embryonic implantation, stem cell self-renewal and cancer progression, etc. LIF exerts...

Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer.

Genes & cancer

Yeh JE, Kreimer S, Walker SR, Emori MM, Krystal H, Richardson A, Ivanov AR, Frank DA.
PMID: 26000098
Genes Cancer. 2015 Mar;6(3):153-68. doi: 10.18632/genesandcancer.58.

Since the neoplastic phenotype of a cell is largely driven by aberrant gene expression patterns, increasing attention has been focused on transcription factors that regulate critical mediators of tumorigenesis such as signal transducer and activator of transcription 3 (STAT3)....

[Expression of leukemia inhibitory factor gene in decidua from women with habitual abortion].

Yi chuan = Hereditas

Li G, Wang YX, Liu XQ, Weng YG, He JL, Chen XM.
PMID: 16126674
Yi Chuan. 2002 May;24(3):251-3.

To evaluate the relationship between habitual abortion of unknown etiology and expression of leukemia inhibitory factor (LIF) gene in the decidua,the expression of LIF gene in the decidua were detected in 32 cases of habitual abortion of unknown etiology...

Role of cytokines in rheumatoid arthritis.

Drug news & perspectives

Odeh M.
PMID: 15616621
Drug News Perspect. 1998 Aug;11(6):331-41. doi: 10.1358/dnp.1998.11.6.661380.

Cytokines have emerged as crucial players in mediating synovial inflammation in the rheumatoid joint, where the local and systemic production of cytokines appears to account for most of the pathologic and clinical manifestations of rheumatoid arthritis. Among the cytokines,...

In vitro characterization of fetal hematopoietic stem cells: range and kinetics of cell production from individual stem cells.

Biotechnology and bioengineering

Young JC, DiGiusto D, Backer MP.
PMID: 18627009
Biotechnol Bioeng. 1996 Jun 05;50(5):465-78. doi: 10.1002/(SICI)1097-0290(19960605)50:5<465::AID-BIT1>3.0.CO;2-D.

We have developed methods for detailed characterization of the proliferation kinetics and lineage potential of single human hematopoietic progenitor cells in an in vitro culture system. Fetal bone marrow CD34(hi)/lin(-) cells were cultured at one cell per well in...

The effects of leukemia inhibitory factor (lif) on cell multiplication and locomotion in human teratocarcinoma cells.

International journal of oncology

Granerus M, Bierke P, Engstrom W.
PMID: 21559730
Int J Oncol. 1994 Dec;5(6):1419-23. doi: 10.3892/ijo.5.6.1419.

The human teratocarcinoma cell line (Tera 2) could be stimulated to a moderate increase in cell number in serum-free medium by addition of 5 ng leukemia inhibitory factor (LIF)/ml. However this effect was only observed in short term (24...

Showing 1 to 12 of 244 entries