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Showing 1 to 12 of 258 entries
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Anti-spasmodic assessment of hydroalcoholic extract and essential oil of aerial part of Pycnocycla caespitosa Boiss. & Hausskn on rat ileum contractions.

Research in pharmaceutical sciences

Sadraei H, Asghari G, Alipour M.
PMID: 27051430
Res Pharm Sci. 2016 Jan-Feb;11(1):33-42.

Pycnocycla caespitosa is an essential oil-containing plant naturally growing in southwest of Iran. The extract of this plant has been used as remedy in traditional medicine. Another species of Pycnocyla (P. spinosa) possessed antispasmodic activity. The pharmacological objective of...

Pharmacologic Agents for Chronic Diarrhea.

Intestinal research

Lee KJ.
PMID: 26576135
Intest Res. 2015 Oct;13(4):306-12. doi: 10.5217/ir.2015.13.4.306. Epub 2015 Oct 15.

Chronic diarrhea is usually associated with a number of non-infectious causes. When definitive treatment is unavailable, symptomatic drug therapy is indicated. Pharmacologic agents for chronic diarrhea include loperamide, 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists, diosmectite, cholestyramine, probiotics, antispasmodics, rifaximin,...

Loperamide Will Stop You Up but It Can Also Bring You Down: Answers to the January 2017 Journal Club questions.

Annals of emergency medicine

Bellew S, Barrett TW.
PMID: 28545698
Ann Emerg Med. 2017 Jun;69(6):786-791. doi: 10.1016/j.annemergmed.2017.02.007.

No abstract available.

Evaluation of the anti-diarrheal activity of the leaf extract of Croton macrostachyus Hocsht. ex Del. (Euphorbiaceae) in mice model.

BMC complementary and alternative medicine

Degu A, Engidawork E, Shibeshi W.
PMID: 27681095
BMC Complement Altern Med. 2016 Sep 29;16(1):379. doi: 10.1186/s12906-016-1357-9.

BACKGROUND: Traditional healers in Ethiopia use a wide range of medicinal plants with antidiarrheal properties. Among these, Croton macrostachyus is one such plant claimed to have an antidiarrheal activity in Ethiopian folklore medicine. Previous studies showed that the crude...

Loperamide Induced Life Threatening Ventricular Arrhythmia.

Case reports in cardiology

Upadhyay A, Bodar V, Malekzadegan M, Singh S, Frumkin W, Mangla A, Doshi K.
PMID: 27547470
Case Rep Cardiol. 2016;2016:5040176. doi: 10.1155/2016/5040176. Epub 2016 Jul 28.

Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors. It is gaining popularity among drug abusers as opioid substitute. We report a case of a 46-year-old male that was presented after cardiac arrest. After ruling out...

Loperamide Induced Torsades de Pointes: A Case Report and Review of the Literature.

Case reports in medicine

Mukarram O, Hindi Y, Catalasan G, Ward J.
PMID: 26989420
Case Rep Med. 2016;2016:4061980. doi: 10.1155/2016/4061980. Epub 2016 Feb 18.

Abuse of over the counter drugs often gets overlooked by health care providers. Loperamide is one such over the counter drug that is often abused by drug addicts. We present here a case of a young male attaining euphoria...

Comprehensive study of buffer systems and local pH effects in electromembrane extraction.

Analytica chimica acta

Restan MS, Jensen H, Shen X, Huang C, Martinsen ØG, Kubáň P, Gjelstad A, Pedersen-Bjergaard S.
PMID: 28843554
Anal Chim Acta. 2017 Sep 01;984:116-123. doi: 10.1016/j.aca.2017.06.049. Epub 2017 Jun 30.

Different phosphate-, acetate- and formate buffers in the pH range 2.0-6.8 were tested for electromembrane extraction (EME) in a 96-well system. The five basic drugs haloperidol, loperamide, methadone, nortriptyline, and pethidine were selected as model analytes. The EME performance...

Loperamide-induced acute pancreatitis.

Case reports in gastrointestinal medicine

Vidarsdottir H, Vidarsdottir H, Moller PH, Bjornsson ES.
PMID: 24198981
Case Rep Gastrointest Med. 2013;2013:517414. doi: 10.1155/2013/517414. Epub 2013 Oct 02.

Acute pancreatitis is a common disease leading to hospitalizations, most often caused by gallstones or alcohol. We present a case of a patient diagnosed with acute pancreatitis considered to be due to loperamide treatment for diarrhea.

Colectomy and acute renal failure: a case report with unusual presentation.

Case reports in nephrology

Sahin OZ, Bilir C, Ayaz T.
PMID: 25143842
Case Rep Nephrol. 2014;2014:821970. doi: 10.1155/2014/821970. Epub 2014 Jul 17.

Surgery is the only curative modality but occasionally it can have some long term complication such as short bowel syndrome. We presented a case reporting a 63-year-old man who had subtotal colectomy with liver metastasectomy according to the colon...

Prevention and management of chemotherapy-induced diarrhea in patients with colorectal cancer: a consensus statement by the Canadian Working Group on Chemotherapy-Induced Diarrhea.

Current oncology (Toronto, Ont.)

Maroun JA, Anthony LB, Blais N, Burkes R, Dowden SD, Dranitsaris G, Samson B, Shah A, Thirlwell MP, Vincent MD, Wong R.
PMID: 17576459
Curr Oncol. 2007 Feb;14(1):13-20. doi: 10.3747/co.2007.96.

Chemotherapy-induced diarrhea (cid) is a common side effect of cancer treatment and can cause significant morbidity and mortality. Diarrhea is frequently severe enough to require a dose reduction of, a delay in, or a discontinuation of chemotherapy. Diarrhea-associated mortality...

ADL-2-1294 (Adolor).

IDrugs : the investigational drugs journal

Wheeler GD.
PMID: 16047259
IDrugs. 2000 Nov;3(11):1373-8.

Adolor is developing various local and topical formulations of the antidiarrheal compound loperamide (ADL-2-1294), which acts as an opiate receptor agonist in the peripheral nervous system, for the potential treatment of pruritus and pain associated with burns, wounds, eye...

Antidiarrheal activity of flowers of Ixora Coccinea Linn. in rats.

Journal of Ayurveda and integrative medicine

Maniyar Y, Bhixavatimath P, Agashikar NV.
PMID: 21731376
J Ayurveda Integr Med. 2010 Oct;1(4):287-91. doi: 10.4103/0975-9476.74422.

Ixora coccinea Linn (Rubiaceae), a small shrub cultivated throughout India, has been reported to possess a number of medicinal properties. It has traditionally been used for the treatment of diarrhea and dysentery. However the claims of Ayurveda have to...

Showing 1 to 12 of 258 entries