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Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome.

PloS one

Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S.
PMID: 27658297
PLoS One. 2016 Sep 22;11(9):e0162974. doi: 10.1371/journal.pone.0162974. eCollection 2016.

We describe a fully automated pipeline for the morphometric phenotyping of mouse brains from μMRI data, and show its application to the Tc1 mouse model of Down syndrome, to identify new morphological phenotypes in the brain of this first...

Interpreting regional differences in neonatal outcomes for extremely preterm babies.

Acta paediatrica (Oslo, Norway : 1992)

Marlow N.
PMID: 24354571
Acta Paediatr. 2014 Jan;103(1):4-5. doi: 10.1111/apa.12518.

No abstract available.

Diffusion imaging changes in grey matter in Alzheimer's disease: a potential marker of early neurodegeneration.

Alzheimer's research & therapy

Weston PS, Simpson IJ, Ryan NS, Ourselin S, Fox NC.
PMID: 26136857
Alzheimers Res Ther. 2015 Jul 01;7(1):47. doi: 10.1186/s13195-015-0132-3. eCollection 2015.

Alzheimer's disease (AD) is recognized to have a long presymptomatic period, during which there is progressive accumulation of molecular pathology, followed by inexorable neuronal damage. The ability to identify presymptomatic individuals with evidence of neurodegenerative change, to stage their...

Showing 1 to 3 of 3 entries