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Showing 1 to 8 of 8 entries
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Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome.

PloS one

Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S.
PMID: 27658297
PLoS One. 2016 Sep 22;11(9):e0162974. doi: 10.1371/journal.pone.0162974. eCollection 2016.

We describe a fully automated pipeline for the morphometric phenotyping of mouse brains from μMRI data, and show its application to the Tc1 mouse model of Down syndrome, to identify new morphological phenotypes in the brain of this first...

Optimising low molecular weight hydrogels for automated 3D printing.

Soft matter

Nolan MC, Fuentes Caparrós AM, Dietrich B, Barrow M, Cross ER, Bleuel M, King SM, Adams DJ.
PMID: 29083003
Soft Matter. 2017 Nov 22;13(45):8426-8432. doi: 10.1039/c7sm01694h.

Hydrogels prepared from low molecular weight gelators (LMWGs) are formed as a result of hierarchical intermolecular interactions between gelators to form fibres, and then further interactions between the self-assembled fibres via physical entanglements, as well as potential branching points....

Autologous Cells for Kidney Bioengineering.

Current transplantation reports

Wilm B, Tamburrini R, Orlando G, Murray P.
PMID: 27547698
Curr Transplant Rep. 2016;3:207-220. doi: 10.1007/s40472-016-0107-8. Epub 2016 Jun 09.

Worldwide, increasing numbers of patients are developing end-stage renal disease, and at present, the only treatment options are dialysis or kidney transplantation. Dialysis is associated with increased morbidity and mortality, poor life quality and high economic costs. Transplantation is...

Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies.

NPJ Regenerative medicine

Scarfe L, Brillant N, Kumar JD, Ali N, Alrumayh A, Amali M, Barbellion S, Jones V, Niemeijer M, Potdevin S, Roussignol G, Vaganov A, Barbaric I, Barrow M, Burton NC, Connell J, Dazzi F, Edsbagge J, French NS, Holder J, Hutchinson C, Jones DR, Kalber T, Lovatt C, Lythgoe MF, Patel S, Patrick PS, Piner J, Reinhardt J, Ricci E, Sidaway J, Stacey GN, Starkey Lewis PJ, Sullivan G, Taylor A, Wilm B, Poptani H, Murray P, Goldring CEP, Park BK.
PMID: 29302362
NPJ Regen Med. 2017 Oct 19;2:28. doi: 10.1038/s41536-017-0029-9. eCollection 2017.

Regenerative medicine therapies hold enormous potential for a variety of currently incurable conditions with high unmet clinical need. Most progress in this field to date has been achieved with cell-based regenerative medicine therapies, with over a thousand clinical trials...

High magnetic relaxivity in a fluorescent CdSe/CdS/ZnS quantum dot functionalized with MRI contrast molecules.

Chemical communications (Cambridge, England)

McAdams SG, Lewis DJ, McNaughter PD, Lewis EA, Haigh SJ, O'Brien P, Tuna F.
PMID: 28828448
Chem Commun (Camb). 2017 Sep 21;53(76):10500-10503. doi: 10.1039/c7cc05537d.

Light emitting semiconducting quantum dots show great promise as solar cells, optoelectronic devices and multimodal imaging probes. Here we demonstrate successful grafting of a thiol-functionalised Gd

Roadmap to clinical translation: insights from a UK regenerative medicine platform workshop on mesenchymal stromal cells.

Regenerative medicine

Asante CO, Dazzi F.
PMID: 29243943
Regen Med. 2017 Dec;12(8):895-897. doi: 10.2217/rme-2017-0097. Epub 2017 Dec 15.

No abstract available.

Magnetic hyperthermia controlled drug release in the GI tract: solving the problem of detection.

Scientific reports

Bear JC, Patrick PS, Casson A, Southern P, Lin FY, Powell MJ, Pankhurst QA, Kalber T, Lythgoe M, Parkin IP, Mayes AG.
PMID: 27671546
Sci Rep. 2016 Sep 27;6:34271. doi: 10.1038/srep34271.

Drug delivery to the gastrointestinal (GI) tract is highly challenging due to the harsh environments any drug- delivery vehicle must experience before it releases it's drug payload. Effective targeted drug delivery systems often rely on external stimuli to effect...

Correction to Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo.

ACS nano

Comenge J, Fragueiro O, Sharkey J, Taylor A, Held M, Burton NC, Park BK, Wilm B, Murray P, Brust M, Lévy R.
PMID: 30106277
ACS Nano. 2018 Aug 28;12(8):8831. doi: 10.1021/acsnano.8b05577. Epub 2018 Aug 14.

No abstract available.

Showing 1 to 8 of 8 entries