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Target Identification of .

Frontiers in pharmacology

Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP.
PMID: 29018348
Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017.

Mycobacterium phenotypic hits are a good reservoir for new chemotypes for the treatment of tuberculosis. However, the absence of defined molecular targets and modes of action could lead to failure in drug development. Therefore, a combination of ligand-based and...

Cite
Mugumbate G, Mendes V, Blaszczyk M, et al. Target Identification of . Front Pharmacol. 2017;8:681doi: 10.3389/fphar.2017.00681.
Mugumbate, G., Mendes, V., Blaszczyk, M., Sabbah, M., Papadatos, G., Lelievre, J., Ballell, L., Barros, D., Abell, C., Blundell, T. L., & Overington, J. P. (2017). Target Identification of . Frontiers in pharmacology, 8681. https://doi.org/10.3389/fphar.2017.00681
Mugumbate, Grace, et al. "Target Identification of ." Frontiers in pharmacology vol. 8 (2017): 681. doi: https://doi.org/10.3389/fphar.2017.00681
Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP. Target Identification of . Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017. PMID: 29018348; PMCID: PMC5623190.
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Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry.

IUCrJ

Blundell TL.
PMID: 28875019
IUCrJ. 2017 Jun 29;4:308-321. doi: 10.1107/S2052252517009241. eCollection 2017 Jul 01.

The development of structure-guided drug discovery is a story of knowledge exchange where new ideas originate from all parts of the research ecosystem. Dorothy Crowfoot Hodgkin obtained insulin from Boots Pure Drug Company in the 1930s and insulin crystallization...

Cite
Blundell TL. Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry. IUCrJ. 2017;4:308-321doi: 10.1107/S2052252517009241.
Blundell, T. L. (2017). Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry. IUCrJ, 4308-321. https://doi.org/10.1107/S2052252517009241
Blundell, Tom L. "Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry." IUCrJ vol. 4 (2017): 308-321. doi: https://doi.org/10.1107/S2052252517009241
Blundell TL. Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry. IUCrJ. 2017 Jun 29;4:308-321. doi: 10.1107/S2052252517009241. eCollection 2017 Jul 01. PMID: 28875019; PMCID: PMC5571795.
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