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Showing 1 to 7 of 7 entries
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Volatile Anesthetic Isoflurane Attenuates Liver Injury in Experimental Polymicrobial Sepsis Model.

Translational perioperative and pain medicine

Koutsogiannaki S, Zha H, Yuki K.
PMID: 29977977
Transl Perioper Pain Med. 2018;5(3):63-74. doi: 10.31480/2330-4871/071. Epub 2018 May 22.

Volatile anesthetics are often administered to patients with sepsis for procedural anesthesia or sedation in intensive care units. Sepsis still carries significant morbidities and mortalities, and organ injuries pose major complications. Early liver dysfunction is associated with poor outcome...

Platelet glycoprotein Ibα provides radiation protection.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Corken A, Ghosh SP, Du R, Boerma M, Ware J, Pathak R.
PMID: 34971661
Radiother Oncol. 2021 Dec 28; doi: 10.1016/j.radonc.2021.12.030. Epub 2021 Dec 28.

BACKGROUND AND PURPOSE: Platelet membrane glycoprotein Ibα (GPIbα), the major ligand-binding subunit of the GPIb-IX-V complex, binds to a number of ligands contributing to hemostasis, thrombosis, and inflammation. Binding to von Willebrand factor (VWF) initiates the process of hemostasis/thrombosis,...

Platelet glycoprotein Ibα provides radiation protection.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Corken A, Ghosh SP, Du R, Boerma M, Ware J, Pathak R.
PMID: 34971661
Radiother Oncol. 2021 Dec 28;167:143-148. doi: 10.1016/j.radonc.2021.12.030. Epub 2021 Dec 28.

BACKGROUND AND PURPOSE: Platelet membrane glycoprotein Ibα (GPIbα), the major ligand-binding subunit of the GPIb-IX-V complex, binds to a number of ligands contributing to hemostasis, thrombosis, and inflammation. Binding to von Willebrand factor (VWF) initiates the process of hemostasis/thrombosis,...

Platelet glycoprotein Ibα provides radiation protection.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Corken A, Ghosh SP, Du R, Boerma M, Ware J, Pathak R.
PMID: 34971661
Radiother Oncol. 2021 Dec 28;167:143-148. doi: 10.1016/j.radonc.2021.12.030. Epub 2021 Dec 28.

BACKGROUND AND PURPOSE: Platelet membrane glycoprotein Ibα (GPIbα), the major ligand-binding subunit of the GPIb-IX-V complex, binds to a number of ligands contributing to hemostasis, thrombosis, and inflammation. Binding to von Willebrand factor (VWF) initiates the process of hemostasis/thrombosis,...

Platelet glycoprotein Ibα provides radiation protection.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Corken A, Ghosh SP, Du R, Boerma M, Ware J, Pathak R.
PMID: 34971661
Radiother Oncol. 2021 Dec 28;167:143-148. doi: 10.1016/j.radonc.2021.12.030. Epub 2021 Dec 28.

BACKGROUND AND PURPOSE: Platelet membrane glycoprotein Ibα (GPIbα), the major ligand-binding subunit of the GPIb-IX-V complex, binds to a number of ligands contributing to hemostasis, thrombosis, and inflammation. Binding to von Willebrand factor (VWF) initiates the process of hemostasis/thrombosis,...

Cell Adhesion Molecules are Upregulated and May Drive Inflammation in Chronic Rhinosinusitis with Nasal Polyposis.

Journal of asthma and allergy

Blight BJ, Gill AS, Sumsion JS, Pollard CE, Ashby S, Oakley GM, Alt JA, Pulsipher A.
PMID: 34079296
J Asthma Allergy. 2021 May 27;14:585-593. doi: 10.2147/JAA.S307197. eCollection 2021.

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly characterized by eosinophil- and T helper 2 cell (Th2)-biased inflammation. Integrins and intercellular adhesion molecules (ICAMs) are superfamilies of cell adhesion molecules (CAMs) that facilitate the recruitment and trafficking of...

MD Simulations on a Well-Built Docking Model Reveal Fine Mechanical Stability and Force-Dependent Dissociation of Mac-1/GPIbα Complex.

Frontiers in molecular biosciences

Jiang X, Sun X, Lin J, Ling Y, Fang Y, Wu J.
PMID: 33968982
Front Mol Biosci. 2021 Apr 22;8:638396. doi: 10.3389/fmolb.2021.638396. eCollection 2021.

Interaction of leukocyte integrin macrophage-1 antigen (Mac-1) to platelet glycoprotein Ibα (GPIbα) is critical for platelet-leukocyte crosstalk in hemostasis and inflammatory responses to vessel injuries under hemodynamic environments. The mechano-regulation and its molecular basis for binding of Mac-1 to...

Showing 1 to 7 of 7 entries