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Showing 1 to 12 of 62 entries
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A modified human ELISPOT assay to detect specific responses to primary tumor cell targets.

Journal of translational medicine

Malyguine A, Strobl SL, Shafer-Weaver KA, Ulderich T, Troke A, Baseler M, Kwak LW, Neelapu SS.
PMID: 15050026
J Transl Med. 2004 Mar 29;2(1):9. doi: 10.1186/1479-5876-2-9.

BACKGROUND: The desired outcome of cancer vaccination is to induce a potent T cell response which can specifically recognize and eliminate autologous tumor cells in vivo. Accordingly, immunological assays that demonstrate recognition of native tumor cells (tumor-specific) may be...

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Malyguine A, Strobl SL, Shafer-Weaver KA, et al. A modified human ELISPOT assay to detect specific responses to primary tumor cell targets. J Transl Med. 2004;2(1):9doi: 10.1186/1479-5876-2-9.
Malyguine, A., Strobl, S. L., Shafer-Weaver, K. A., Ulderich, T., Troke, A., Baseler, M., Kwak, L. W., & Neelapu, S. S. (2004). A modified human ELISPOT assay to detect specific responses to primary tumor cell targets. Journal of translational medicine, 2(1), 9. https://doi.org/10.1186/1479-5876-2-9
Malyguine, Anatoli, et al. "A modified human ELISPOT assay to detect specific responses to primary tumor cell targets." Journal of translational medicine vol. 2,1 (2004): 9. doi: https://doi.org/10.1186/1479-5876-2-9
Malyguine A, Strobl SL, Shafer-Weaver KA, Ulderich T, Troke A, Baseler M, Kwak LW, Neelapu SS. A modified human ELISPOT assay to detect specific responses to primary tumor cell targets. J Transl Med. 2004 Mar 29;2(1):9. doi: 10.1186/1479-5876-2-9. PMID: 15050026; PMCID: PMC415560.
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Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional study.

BMC blood disorders

Zhang M, O'brien TR, Kopp WC, Goedert JJ.
PMID: 15656905
BMC Blood Disord. 2005 Jan 18;5(1):2. doi: 10.1186/1471-2326-5-2.

BACKGROUND: With chronic infection, hepatitis C virus (HCV) RNA can be detected in B cells and associated with B-cell disorders, but these are not well defined. METHODS: The relationship between HCV infection and lymphocyte subpopulations was evaluated rigorously in...

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Zhang M, O'brien TR, Kopp WC, et al. Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional study. BMC Blood Disord. 2005;5(1):2doi: 10.1186/1471-2326-5-2.
Zhang, M., O'brien, T. R., Kopp, W. C., Goedert, J. J. (2005). Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional study. BMC blood disorders, 5(1), 2. https://doi.org/10.1186/1471-2326-5-2
Zhang, Mingdong, et al. "Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional study." BMC blood disorders vol. 5,1 (2005): 2. doi: https://doi.org/10.1186/1471-2326-5-2
Zhang M, O'brien TR, Kopp WC, Goedert JJ. Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional study. BMC Blood Disord. 2005 Jan 18;5(1):2. doi: 10.1186/1471-2326-5-2. PMID: 15656905; PMCID: PMC546217.
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Stereoselective Synthesis of Quaternary Proline Analogues.

European journal of organic chemistry

Calaza MI, Cativiela C.
PMID: 19655047
European J Org Chem. 2008;20:3427-3448. doi: 10.1002/ejoc.200800225.

This review describes available methods for the diastereoselective and asymmetric synthesis of quaternary prolines. The focus is on the preparation of alpha-functionalized prolines with the pyrrolidine moiety not embedded in a polycyclic frame. The diverse synthetic approaches are classified...

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Calaza MI, Cativiela C. Stereoselective Synthesis of Quaternary Proline Analogues. European J Org Chem. 2008;20:3427-3448doi: 10.1002/ejoc.200800225.
Calaza, M. I., & Cativiela, C. (2008). Stereoselective Synthesis of Quaternary Proline Analogues. European journal of organic chemistry, 203427-3448. https://doi.org/10.1002/ejoc.200800225
Calaza, M Isabel, and Cativiela, Carlos. "Stereoselective Synthesis of Quaternary Proline Analogues." European journal of organic chemistry vol. 20 (2008): 3427-3448. doi: https://doi.org/10.1002/ejoc.200800225
Calaza MI, Cativiela C. Stereoselective Synthesis of Quaternary Proline Analogues. European J Org Chem. 2008;20:3427-3448. doi: 10.1002/ejoc.200800225. PMID: 19655047; PMCID: PMC2719988.
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Conformation dependence of pKa's of the chromophores from the purple asFP595 and yellow zFP538 fluorescent proteins.

Theochem

Nemukhin AV, Topol IA, Grigorenko BL, Savitsky AP, Collins JR.
PMID: 19721695
Theochem. 2008 Aug 30;863(1):39-43. doi: 10.1016/j.theochem.2008.05.014.

Two members of the green fluorescent protein family, the purple asFP595 and yellow zFP538 proteins, are perspective fluorescent markers for use in multicolor imaging and resonance energy-transfer applications. We report the results of quantum based calculations of the solution...

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Nemukhin AV, Topol IA, Grigorenko BL, et al. Conformation dependence of pKa's of the chromophores from the purple asFP595 and yellow zFP538 fluorescent proteins. Theochem. 2008;863(1):39-43doi: 10.1016/j.theochem.2008.05.014.
Nemukhin, A. V., Topol, I. A., Grigorenko, B. L., Savitsky, A. P., & Collins, J. R. (2008). Conformation dependence of pKa's of the chromophores from the purple asFP595 and yellow zFP538 fluorescent proteins. Theochem, 863(1), 39-43. https://doi.org/10.1016/j.theochem.2008.05.014
Nemukhin, A V, et al. "Conformation dependence of pKa's of the chromophores from the purple asFP595 and yellow zFP538 fluorescent proteins." Theochem vol. 863,1 (2008): 39-43. doi: https://doi.org/10.1016/j.theochem.2008.05.014
Nemukhin AV, Topol IA, Grigorenko BL, Savitsky AP, Collins JR. Conformation dependence of pKa's of the chromophores from the purple asFP595 and yellow zFP538 fluorescent proteins. Theochem. 2008 Aug 30;863(1):39-43. doi: 10.1016/j.theochem.2008.05.014. PMID: 19721695; PMCID: PMC2598386.
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Magnetic resonance assessment of response to therapy: tumor change measurement, truth data and error sources.

Translational oncology

Jackson EF, Barboriak DP, Bidaut LM, Meyer CR.
PMID: 19956380
Transl Oncol. 2009 Dec;2(4):211-5. doi: 10.1593/tlo.09241.

This article describes methods and issues that are specific to the assessment of change in tumor characteristics as measured using quantitative magnetic resonance (MR) techniques and how this relates to the establishment of quantitative MR imaging (MRI) biomarkers of...

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Jackson EF, Barboriak DP, Bidaut LM, et al. Magnetic resonance assessment of response to therapy: tumor change measurement, truth data and error sources. Transl Oncol. 2009;2(4):211-5doi: 10.1593/tlo.09241.
Jackson, E. F., Barboriak, D. P., Bidaut, L. M., & Meyer, C. R. (2009). Magnetic resonance assessment of response to therapy: tumor change measurement, truth data and error sources. Translational oncology, 2(4), 211-5. https://doi.org/10.1593/tlo.09241
Jackson, Edward F, et al. "Magnetic resonance assessment of response to therapy: tumor change measurement, truth data and error sources." Translational oncology vol. 2,4 (2009): 211-5. doi: https://doi.org/10.1593/tlo.09241
Jackson EF, Barboriak DP, Bidaut LM, Meyer CR. Magnetic resonance assessment of response to therapy: tumor change measurement, truth data and error sources. Transl Oncol. 2009 Dec;2(4):211-5. doi: 10.1593/tlo.09241. PMID: 19956380; PMCID: PMC2781079.
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Bringing diagnostic technologies to the clinical laboratory: Rigor, regulation, and reality.

Proteomics. Clinical applications

Whiteley G.
PMID: 19325937
Proteomics Clin Appl. 2008;2(10):1378-1385. doi: 10.1002/prca.200780170.

With the numerous reports of new technologies and biomarkers reported in the literature, it may be surprising that there are not an equal number of new products available to the clinical diagnostic laboratory. Powerful potential tools such as protein...

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Whiteley G. Bringing diagnostic technologies to the clinical laboratory: Rigor, regulation, and reality. Proteomics Clin Appl. 2008;2(10):1378-1385doi: 10.1002/prca.200780170.
Whiteley, G. (2008). Bringing diagnostic technologies to the clinical laboratory: Rigor, regulation, and reality. Proteomics. Clinical applications, 2(10), 1378-1385. https://doi.org/10.1002/prca.200780170
Whiteley, Gordon. "Bringing diagnostic technologies to the clinical laboratory: Rigor, regulation, and reality." Proteomics. Clinical applications vol. 2,10 (2008): 1378-1385. doi: https://doi.org/10.1002/prca.200780170
Whiteley G. Bringing diagnostic technologies to the clinical laboratory: Rigor, regulation, and reality. Proteomics Clin Appl. 2008;2(10):1378-1385. doi: 10.1002/prca.200780170. PMID: 19325937; PMCID: PMC2660881.
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Towards Building a High Performance Spatial Query System for Large Scale Medical Imaging Data.

Proceedings of the ... ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems : ACM GIS. ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems

Aji A, Wang F, Saltz JH.
PMID: 24501719
Proc ACM SIGSPATIAL Int Conf Adv Inf. 2012 Nov 06;2012:309-318. doi: 10.1145/2424321.2424361.

Support of high performance queries on large volumes of scientific spatial data is becoming increasingly important in many applications. This growth is driven by not only geospatial problems in numerous fields, but also emerging scientific applications that are increasingly...

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Aji A, Wang F, Saltz JH. Towards Building a High Performance Spatial Query System for Large Scale Medical Imaging Data. Proc ACM SIGSPATIAL Int Conf Adv Inf. 2012;2012:309-318doi: 10.1145/2424321.2424361.
Aji, A., Wang, F., & Saltz, J. H. (2012). Towards Building a High Performance Spatial Query System for Large Scale Medical Imaging Data. Proceedings of the ... ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems : ACM GIS. ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems, 2012309-318. https://doi.org/10.1145/2424321.2424361
Aji, Ablimit, et al. "Towards Building a High Performance Spatial Query System for Large Scale Medical Imaging Data." Proceedings of the ... ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems : ACM GIS. ACM SIGSPATIAL International Conference on Advances in Geographic Information Systems vol. 2012 (2012): 309-318. doi: https://doi.org/10.1145/2424321.2424361
Aji A, Wang F, Saltz JH. Towards Building a High Performance Spatial Query System for Large Scale Medical Imaging Data. Proc ACM SIGSPATIAL Int Conf Adv Inf. 2012 Nov 06;2012:309-318. doi: 10.1145/2424321.2424361. PMID: 24501719; PMCID: PMC3909999.
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A Unique Case of Classic Kaposi's sarcoma restricted to the toes.

Journal of dermatological case reports

Renteria AS, Marshall VA, Sun Y, Chockalingam P, Cooper JS, Huang Y, Whitby D.
PMID: 24133565
J Dermatol Case Rep. 2013 Sep 30;7(3):97-100. doi: 10.3315/jdcr.2013.1146. eCollection 2013.

BACKGROUND: Kaposi's sarcoma associated-herpesvirus causes all forms of Kaposi's sarcoma, and six major subtypes have been described based on the amino acid sequences of the open reading frame K1.MAIN OBSERVATION: A 71-year-old man from China, HIV negative, presented with...

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Renteria AS, Marshall VA, Sun Y, et al. A Unique Case of Classic Kaposi's sarcoma restricted to the toes. J Dermatol Case Rep. 2013;7(3):97-100doi: 10.3315/jdcr.2013.1146.
Renteria, A. S., Marshall, V. A., Sun, Y., Chockalingam, P., Cooper, J. S., Huang, Y., & Whitby, D. (2013). A Unique Case of Classic Kaposi's sarcoma restricted to the toes. Journal of dermatological case reports, 7(3), 97-100. https://doi.org/10.3315/jdcr.2013.1146
Renteria, Anne S, et al. "A Unique Case of Classic Kaposi's sarcoma restricted to the toes." Journal of dermatological case reports vol. 7,3 (2013): 97-100. doi: https://doi.org/10.3315/jdcr.2013.1146
Renteria AS, Marshall VA, Sun Y, Chockalingam P, Cooper JS, Huang Y, Whitby D. A Unique Case of Classic Kaposi's sarcoma restricted to the toes. J Dermatol Case Rep. 2013 Sep 30;7(3):97-100. doi: 10.3315/jdcr.2013.1146. eCollection 2013. PMID: 24133565; PMCID: PMC3797018.
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High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis.

Blood advances

Lombardo KA, Coffey DG, Morales AJ, Carlson CS, Towlerton AMH, Gerdts SE, Nkrumah FK, Neequaye J, Biggar RJ, Orem J, Casper C, Mbulaiteye SM, Bhatia KG, Warren EH.
PMID: 29296973
Blood Adv. 2017 Mar 21;1(9):535-544. doi: 10.1182/bloodadvances.2016000794. eCollection 2017 Mar 28.

Burkitt lymphoma (BL), the most common pediatric cancer in sub-Saharan Africa, is a malignancy of antigen-experienced B lymphocytes. High-throughput sequencing (HTS) of the immunoglobulin heavy (

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Lombardo KA, Coffey DG, Morales AJ, et al. High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis. Blood Adv. 2017;1(9):535-544doi: 10.1182/bloodadvances.2016000794.
Lombardo, K. A., Coffey, D. G., Morales, A. J., Carlson, C. S., Towlerton, A. M. H., Gerdts, S. E., Nkrumah, F. K., Neequaye, J., Biggar, R. J., Orem, J., Casper, C., Mbulaiteye, S. M., Bhatia, K. G., & Warren, E. H. (2017). High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis. Blood advances, 1(9), 535-544. https://doi.org/10.1182/bloodadvances.2016000794
Lombardo, Katharine A, et al. "High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis." Blood advances vol. 1,9 (2017): 535-544. doi: https://doi.org/10.1182/bloodadvances.2016000794
Lombardo KA, Coffey DG, Morales AJ, Carlson CS, Towlerton AMH, Gerdts SE, Nkrumah FK, Neequaye J, Biggar RJ, Orem J, Casper C, Mbulaiteye SM, Bhatia KG, Warren EH. High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis. Blood Adv. 2017 Mar 21;1(9):535-544. doi: 10.1182/bloodadvances.2016000794. eCollection 2017 Mar 28. PMID: 29296973; PMCID: PMC5728594.
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A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS.

Proceedings. IEEE International Symposium on Biomedical Imaging

Kong J, Cooper L, Wang F, Chisolm C, Moreno C, Kurc T, Widener P, Brat D, Saltz J.
PMID: 22249771
Proc IEEE Int Symp Biomed Imaging. 2011 Mar 30;2128-2131. doi: 10.1109/ISBI.2011.5872833.

In this paper, we present a comprehensive framework to support classification of nuclei in digital microscopy images of diffuse gliomas. This system integrates multiple modules designed for convenient human annotations, standard-based data management, efficient data query and analysis. In...

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Kong J, Cooper L, Wang F, et al. A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS. Proc IEEE Int Symp Biomed Imaging. 2011;2128-2131doi: 10.1109/ISBI.2011.5872833.
Kong, J., Cooper, L., Wang, F., Chisolm, C., Moreno, C., Kurc, T., Widener, P., Brat, D., & Saltz, J. (2011). A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS. Proceedings. IEEE International Symposium on Biomedical Imaging, 2128-2131. https://doi.org/10.1109/ISBI.2011.5872833
Kong, Jun, et al. "A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS." Proceedings. IEEE International Symposium on Biomedical Imaging vol. (2011): 2128-2131. doi: https://doi.org/10.1109/ISBI.2011.5872833
Kong J, Cooper L, Wang F, Chisolm C, Moreno C, Kurc T, Widener P, Brat D, Saltz J. A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS. Proc IEEE Int Symp Biomed Imaging. 2011 Mar 30;2128-2131. doi: 10.1109/ISBI.2011.5872833. PMID: 22249771; PMCID: PMC3256584.
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e-Science, caGrid, and Translational Biomedical Research.

Computer

Saltz J, Kurc T, Hastings S, Langella S, Oster S, Ervin D, Sharma A, Pan T, Gurcan M, Permar J, Ferreira R, Payne P, Catalyurek U, Caserta E, Leone G, Ostrowski MC, Madduri R, Foster I, Madhavan S, Buetow KH, Shanbhag K, Siegel E.
PMID: 21311723
Computer (Long Beach Calif). 2008 Nov;41(11):58-66. doi: 10.1109/MC.2008.459.

Translational research projects target a wide variety of diseases, test many different kinds of biomedical hypotheses, and employ a large assortment of experimental methodologies. Diverse data, complex execution environments, and demanding security and reliability requirements make the implementation of...

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Saltz J, Kurc T, Hastings S, et al. e-Science, caGrid, and Translational Biomedical Research. Computer (Long Beach Calif). 2008;41(11):58-66doi: 10.1109/MC.2008.459.
Saltz, J., Kurc, T., Hastings, S., Langella, S., Oster, S., Ervin, D., Sharma, A., Pan, T., Gurcan, M., Permar, J., Ferreira, R., Payne, P., Catalyurek, U., Caserta, E., Leone, G., Ostrowski, M. C., Madduri, R., Foster, I., Madhavan, S., Buetow, K. H., Shanbhag, K., & Siegel, E. (2008). e-Science, caGrid, and Translational Biomedical Research. Computer, 41(11), 58-66. https://doi.org/10.1109/MC.2008.459
Saltz, Joel, et al. "e-Science, caGrid, and Translational Biomedical Research." Computer vol. 41,11 (2008): 58-66. doi: https://doi.org/10.1109/MC.2008.459
Saltz J, Kurc T, Hastings S, Langella S, Oster S, Ervin D, Sharma A, Pan T, Gurcan M, Permar J, Ferreira R, Payne P, Catalyurek U, Caserta E, Leone G, Ostrowski MC, Madduri R, Foster I, Madhavan S, Buetow KH, Shanbhag K, Siegel E. e-Science, caGrid, and Translational Biomedical Research. Computer (Long Beach Calif). 2008 Nov;41(11):58-66. doi: 10.1109/MC.2008.459. PMID: 21311723; PMCID: PMC3035203.
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Chemical phylogenetics of histone deacetylases.

Nature chemical biology

Bradner JE, West N, Grachan ML, Greenberg EF, Haggarty SJ, Warnow T, Mazitschek R.
PMID: 20139990
Nat Chem Biol. 2010 Mar;6(3):238-243. doi: 10.1038/nchembio.313. Epub 2010 Feb 07.

The broad study of histone deacetylases in chemistry, biology and medicine relies on tool compounds to derive mechanistic insights. A phylogenetic analysis of class I and II histone deacetylases (HDACs) as targets of a comprehensive, structurally diverse panel of...

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Bradner JE, West N, Grachan ML, et al. Chemical phylogenetics of histone deacetylases. Nat Chem Biol. 2010;6(3):238-243doi: 10.1038/nchembio.313.
Bradner, J. E., West, N., Grachan, M. L., Greenberg, E. F., Haggarty, S. J., Warnow, T., & Mazitschek, R. (2010). Chemical phylogenetics of histone deacetylases. Nature chemical biology, 6(3), 238-243. https://doi.org/10.1038/nchembio.313
Bradner, James E, et al. "Chemical phylogenetics of histone deacetylases." Nature chemical biology vol. 6,3 (2010): 238-243. doi: https://doi.org/10.1038/nchembio.313
Bradner JE, West N, Grachan ML, Greenberg EF, Haggarty SJ, Warnow T, Mazitschek R. Chemical phylogenetics of histone deacetylases. Nat Chem Biol. 2010 Mar;6(3):238-243. doi: 10.1038/nchembio.313. Epub 2010 Feb 07. PMID: 20139990; PMCID: PMC2822059.
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Showing 1 to 12 of 62 entries