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Showing 1 to 11 of 11 entries
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Cox Models With Smooth Functional Effect of Covariates Measured With Error.

Journal of the American Statistical Association

Cheng YJ, Crainiceanu CM.
PMID: 21818167
J Am Stat Assoc. 2009 Sep 01;104(487):1144-1154. doi: 10.1198/jasa.2009.tm08160.

We propose, develop, and implement a fully Bayesian inferential approach for the Cox model when the log hazard function contains unknown smooth functions of the variables measured with error. Our approach is to model nonparametrically both the log-baseline hazard...

Stroke Mortality, Clinical Presentation and Day of Arrival: The Atherosclerosis Risk in Communities (ARIC) Study.

Stroke research and treatment

O'Brien EC, Rose KM, Shahar E, Rosamond WD.
PMID: 21772968
Stroke Res Treat. 2011;2011:383012. doi: 10.4061/2011/383012. Epub 2011 May 05.

Background. Recent studies report that acute stroke patients who present to the hospital on weekends have higher rates of 28-day mortality than similar patients who arrive during the week. However, how this association is related to clinical presentation and...

Television, physical activity, diet, and body weight status: the ARIC cohort.

The international journal of behavioral nutrition and physical activity

Meyer AM, Evenson KR, Couper DJ, Stevens J, Pereria MA, Heiss G.
PMID: 19091124
Int J Behav Nutr Phys Act. 2008 Dec 17;5:68. doi: 10.1186/1479-5868-5-68.

BACKGROUND: Television (TV) watching is the most common leisure activity in the United States. Few studies of adults have described the relationship between TV and health behaviors such as physical activity, diet, and body weight status.METHODS: Extant data from...

Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.

American journal of hematology

Jo Hodonsky C, Schurmann C, Schick UM, Kocarnik J, Tao R, van Rooij FJ, Wassel C, Buyske S, Fornage M, Hindorff LA, Floyd JS, Ganesh SK, Lin DY, North KE, Reiner AP, Loos RJ, Kooperberg C, Avery CL.
PMID: 29905378
Am J Hematol. 2018 Jun 15; doi: 10.1002/ajh.25161. Epub 2018 Jun 15.

Red blood cell (RBC) traits provide insight into a wide range of physiological states and exhibit moderate to high heritability, making them excellent candidates for genetic studies to inform underlying biologic mechanisms. Previous RBC trait genome-wide association studies were...

Longitudinal development of incident gout from low-normal baseline serum urate concentrations: individual participant data analysis.

BMC rheumatology

Robinson PC, Frampton C, Phipps-Green A, Neogi T, Stamp L, Taylor W, Merriman TR, Dalbeth N.
PMID: 34452645
BMC Rheumatol. 2021 Aug 28;5(1):33. doi: 10.1186/s41927-021-00204-4.

INTRODUCTION: Elevated serum urate (SU) concentration is the central risk factor for the development of gout. The aim of this study was to examine the incidence of gout in people with low and normal SU levels (

Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women.

Frontiers in genetics

Topless RK, Flynn TJ, Cadzow M, Stamp LK, Dalbeth N, Black MA, Merriman TR.
PMID: 26528330
Front Genet. 2015 Oct 14;6:313. doi: 10.3389/fgene.2015.00313. eCollection 2015.

The SLC2A9 gene, that encodes a renal uric acid reuptake transporter, has genetic variants that explain ∼3% of variance in urate levels. There are previous reports of non-additive interaction between SLC2A9 genotype and environmental factors which influence urate control....

Marital Status, Hypertension, Coronary Heart Disease, Diabetes, and Death Among African American Women and Men: Incidence and Prevalence in the Atherosclerosis Risk in Communities (ARIC) Study Participants.

Journal of family issues

Schwandt HM, Coresh J, Hindin MJ.
PMID: 26752799
J Fam Issues. 2010 Sep;31(9):1211-1229. doi: 10.1177/0192513X10365487.

No abstract available.

Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

PLoS genetics

Liu CT, Monda KL, Taylor KC, Lange L, Demerath EW, Palmas W, Wojczynski MK, Ellis JC, Vitolins MZ, Liu S, Papanicolaou GJ, Irvin MR, Xue L, Griffin PJ, Nalls MA, Adeyemo A, Liu J, Li G, Ruiz-Narvaez EA, Chen WM, Chen F, Henderson BE, Millikan RC, Ambrosone CB, Strom SS, Guo X, Andrews JS, Sun YV, Mosley TH, Yanek LR, Shriner D, Haritunians T, Rotter JI, Speliotes EK, Smith M, Rosenberg L, Mychaleckyj J, Nayak U, Spruill I, Garvey WT, Pettaway C, Nyante S, Bandera EV, Britton AF, Zonderman AB, Rasmussen-Torvik LJ, Chen YD, Ding J, Lohman K, Kritchevsky SB, Zhao W, Peyser PA, Kardia SL, Kabagambe E, Broeckel U, Chen G, Zhou J, Wassertheil-Smoller S, Neuhouser ML, Rampersaud E, Psaty B, Kooperberg C, Manson JE, Kuller LH, Ochs-Balcom HM, Johnson KC, Sucheston L, Ordovas JM, Palmer JR, Haiman CA, McKnight B, Howard BV, Becker DM, Bielak LF, Liu Y, Allison MA, Grant SF, Burke GL, Patel SR, Schreiner PJ, Borecki IB, Evans MK, Taylor H, Sale MM, Howard V, Carlson CS, Rotimi CN, Cushman M, Harris TB, Reiner AP, Cupples LA, North KE, Fox CS.
PMID: 23966867
PLoS Genet. 2013;9(8):e1003681. doi: 10.1371/journal.pgen.1003681. Epub 2013 Aug 15.

Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker of body fat distribution. Although obesity disproportionately affects minority populations, few studies have conducted genome-wide association study (GWAS) of fat distribution among those of predominantly...

Improved Horvitz-Thompson Estimation of Model Parameters from Two-phase Stratified Samples: Applications in Epidemiology.

Statistics in biosciences

Breslow NE, Lumley T, Ballantyne CM, Chambless LE, Kulich M.
PMID: 20174455
Stat Biosci. 2009 May 01;1(1):32. doi: 10.1007/s12561-009-9001-6.

The case-cohort study involves two-phase sampling: simple random sampling from an infinite super-population at phase one and stratified random sampling from a finite cohort at phase two. Standard analyses of case-cohort data involve solution of inverse probability weighted (IPW)...

Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study.

Journal of obesity

Kucharska-Newton AM, Monda KL, Bielinski SJ, Boerwinkle E, Rea TD, Rosamond WD, Pankow JS, Köttgen A, Heiss G, North KE.
PMID: 20798759
J Obes. 2010;2010. doi: 10.1155/2010/651903. Epub 2010 Feb 22.

We examined the association of variation in the type 2 diabetes risk-conferring TCF7L2 gene with the risk of incident coronary heart disease (CHD) among the lean, overweight, and obese members of the Atherosclerosis Risk in Communities (ARIC) Study cohort....

Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.

Genome medicine

Meeks KAC, Bentley AR, Gouveia MH, Chen G, Zhou J, Lei L, Adeyemo AA, Doumatey AP, Rotimi CN.
PMID: 34620218
Genome Med. 2021 Oct 07;13(1):156. doi: 10.1186/s13073-021-00971-2.

BACKGROUND: A complex set of perturbations occur in cytokines and hormones in the etiopathogenesis of obesity and related cardiometabolic conditions such as type 2 diabetes (T2D). Evidence for the genetic regulation of these cytokines and hormones is limited, particularly...

Showing 1 to 11 of 11 entries