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Showing 1 to 12 of 35 entries
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Silver(I) complexes containing diclofenac and niflumic acid induce apoptosis in human-derived cancer cell lines.

Archives of physiology and biochemistry

Altay A, Caglar S, Caglar B.
PMID: 31516039
Arch Physiol Biochem. 2019 Sep 13;1-11. doi: 10.1080/13813455.2019.1662454. Epub 2019 Sep 13.

We investigated the anti-cancer activity of [Ag(μ-dicl)]

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Altay A, Caglar S, Caglar B. Silver(I) complexes containing diclofenac and niflumic acid induce apoptosis in human-derived cancer cell lines. Arch Physiol Biochem. 2019;1-11doi: 10.1080/13813455.2019.1662454.
Altay, A., Caglar, S., & Caglar, B. (2019). Silver(I) complexes containing diclofenac and niflumic acid induce apoptosis in human-derived cancer cell lines. Archives of physiology and biochemistry, 1-11. https://doi.org/10.1080/13813455.2019.1662454
Altay, Ahmet, et al. "Silver(I) complexes containing diclofenac and niflumic acid induce apoptosis in human-derived cancer cell lines." Archives of physiology and biochemistry vol. (2019): 1-11. doi: https://doi.org/10.1080/13813455.2019.1662454
Altay A, Caglar S, Caglar B. Silver(I) complexes containing diclofenac and niflumic acid induce apoptosis in human-derived cancer cell lines. Arch Physiol Biochem. 2019 Sep 13;1-11. doi: 10.1080/13813455.2019.1662454. Epub 2019 Sep 13. PMID: 31516039.
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Interactions of Anti-Inflammatory and Antibiotic Drugs at Mineral Surfaces Can Control Environmental Fate and Transport.

Environmental science & technology

Luo T, Xu J, Cheng W, Zhou L, Marsac R, Wu F, Boily JF, Hanna K.
PMID: 34910456
Environ Sci Technol. 2021 Dec 15; doi: 10.1021/acs.est.1c06449. Epub 2021 Dec 15.

Various pharmaceutical compounds often coexist in contaminated soils, yet little is known about how their interactions impact their mobility. We here show that two typical antibiotic and anti-inflammatory agents (nalidixic acid (NA) and niflumic acid (NFA)) commonly form dimers...

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Luo T, Xu J, Cheng W, et al. Interactions of Anti-Inflammatory and Antibiotic Drugs at Mineral Surfaces Can Control Environmental Fate and Transport. Environ Sci Technol. 2021;doi: 10.1021/acs.est.1c06449.
Luo, T., Xu, J., Cheng, W., Zhou, L., Marsac, R., Wu, F., Boily, J. F., & Hanna, K. (2021). Interactions of Anti-Inflammatory and Antibiotic Drugs at Mineral Surfaces Can Control Environmental Fate and Transport. Environmental science & technology, . https://doi.org/10.1021/acs.est.1c06449
Luo, Tao, et al. "Interactions of Anti-Inflammatory and Antibiotic Drugs at Mineral Surfaces Can Control Environmental Fate and Transport." Environmental science & technology vol. (2021). doi: https://doi.org/10.1021/acs.est.1c06449
Luo T, Xu J, Cheng W, Zhou L, Marsac R, Wu F, Boily JF, Hanna K. Interactions of Anti-Inflammatory and Antibiotic Drugs at Mineral Surfaces Can Control Environmental Fate and Transport. Environ Sci Technol. 2021 Dec 15; doi: 10.1021/acs.est.1c06449. Epub 2021 Dec 15. PMID: 34910456.
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In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data.

Crystal growth & design

Vázquez Marrero VR, Berríos CP, Dios Rodríguez L, Stelzer T, López-Mejías V.
PMID: 32863778
Cryst Growth Des. 2019;19(7):4101-4108. doi: 10.1021/acs.cgd.9b00529. Epub 2019 Jun 07.

Solubility measurements for polymorphic compounds are often accompanied by solvent-mediated phase transformations. In this study, solubility measurements from undersaturated solutions are employed to investigate the solubility of the two most stable polymorphs of flufenamic acid (FFA forms I and...

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Vázquez Marrero VR, Berríos CP, Dios Rodríguez L, et al. In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data. Cryst Growth Des. 2019;19(7):4101-4108doi: 10.1021/acs.cgd.9b00529.
Vázquez Marrero, V. R., Berríos, C. P., Dios Rodríguez, L., Stelzer, T., & López-Mejías, V. (2019). In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data. Crystal growth & design, 19(7), 4101-4108. https://doi.org/10.1021/acs.cgd.9b00529
Vázquez Marrero, Víctor R, et al. "In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data." Crystal growth & design vol. 19,7 (2019): 4101-4108. doi: https://doi.org/10.1021/acs.cgd.9b00529
Vázquez Marrero VR, Berríos CP, Dios Rodríguez L, Stelzer T, López-Mejías V. In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data. Cryst Growth Des. 2019;19(7):4101-4108. doi: 10.1021/acs.cgd.9b00529. Epub 2019 Jun 07. PMID: 32863778; PMCID: PMC7453630.
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Ion channel activity during the action potential in Chara: new insights with new techniques.

Journal of experimental botany

Thiel G, Homann U, Plieth C.
PMID: 21245235
J Exp Bot. 1997 Mar;48:609-22. doi: 10.1093/jxb/48.Special_Issue.609.

The dynamics of macroscopic currents underlying the electrically triggered action potential (AP) in the giant alga Chara corallina were directly recorded with an action potential clamp method. In this technique an AP is recorded and repetitively replayed as the...

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Thiel G, Homann U, Plieth C. Ion channel activity during the action potential in Chara: new insights with new techniques. J Exp Bot. 1997;48:609-22doi: 10.1093/jxb/48.Special_Issue.609.
Thiel, G., Homann, U., & Plieth, C. (1997). Ion channel activity during the action potential in Chara: new insights with new techniques. Journal of experimental botany, 48609-22. https://doi.org/10.1093/jxb/48.Special_Issue.609
Thiel, G, et al. "Ion channel activity during the action potential in Chara: new insights with new techniques." Journal of experimental botany vol. 48 (1997): 609-22. doi: https://doi.org/10.1093/jxb/48.Special_Issue.609
Thiel G, Homann U, Plieth C. Ion channel activity during the action potential in Chara: new insights with new techniques. J Exp Bot. 1997 Mar;48:609-22. doi: 10.1093/jxb/48.Special_Issue.609. PMID: 21245235.
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Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice.

The e-journal of neonatology research

Vucovich M, Ehinger N, Poole SD, Lamb FS, Reese J.
PMID: 23710420
EJ Neonatol Res. 2012 Jan;2(1):13-24.

The mechanisms that regulate relaxation of the fetal ductus arteriosus (DA) and its postnatal constriction are the subject of ongoing studies. Using pressure myography, a pattern of rhythmic oscillatory contractions termed vasomotion was observed in the isolated DA of...

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Vucovich M, Ehinger N, Poole SD, et al. Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice. EJ Neonatol Res. 2012;2(1):13-24
Vucovich, M., Ehinger, N., Poole, S. D., Lamb, F. S., & Reese, J. (2012). Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice. The e-journal of neonatology research, 2(1), 13-24.
Vucovich, Megan, et al. "Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice." The e-journal of neonatology research vol. 2,1 (2012): 13-24.
Vucovich M, Ehinger N, Poole SD, Lamb FS, Reese J. Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice. EJ Neonatol Res. 2012 Jan;2(1):13-24. PMID: 23710420; PMCID: PMC3661283.
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Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder.

Frontiers in physiology

Chakrabarty B, Bijos DA, Vahabi B, Clavica F, Kanai AJ, Pickering AE, Fry CH, Drake MJ.
PMID: 30687132
Front Physiol. 2019 Jan 10;9:1937. doi: 10.3389/fphys.2018.01937. eCollection 2018.

Micromotions are phasic contractions of the bladder wall. During urine storage, such phasic activity has little effect on intravesical pressure, however, changed motile activity may underlie urodynamic observations such as detrusor overactivity. The potential for bladder motility to affect...

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Chakrabarty B, Bijos DA, Vahabi B, et al. Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder. Front Physiol. 2019;9:1937doi: 10.3389/fphys.2018.01937.
Chakrabarty, B., Bijos, D. A., Vahabi, B., Clavica, F., Kanai, A. J., Pickering, A. E., Fry, C. H., & Drake, M. J. (2018). Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder. Frontiers in physiology, 91937. https://doi.org/10.3389/fphys.2018.01937
Chakrabarty, Basu, et al. "Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder." Frontiers in physiology vol. 9 (2018): 1937. doi: https://doi.org/10.3389/fphys.2018.01937
Chakrabarty B, Bijos DA, Vahabi B, Clavica F, Kanai AJ, Pickering AE, Fry CH, Drake MJ. Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder. Front Physiol. 2019 Jan 10;9:1937. doi: 10.3389/fphys.2018.01937. eCollection 2018. PMID: 30687132; PMCID: PMC6335571.
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The solid state of anti-inflammatory morniflumate diniflumate: A cocrystalline salt.

International journal of pharmaceutics

Barrio M, Ceolin R, Robert B, Allouchi H, Teulon JM, Guéchot C, Tamarit JL, Rietveld IB.
PMID: 34710544
Int J Pharm. 2021 Dec 15;610:121224. doi: 10.1016/j.ijpharm.2021.121224. Epub 2021 Oct 25.

Morniflumate diniflumate, a molecular compound involving niflumic acid and its β-morpholino ethyl ester (morniflumate) in the mole ratio 2:1, is found to crystallize in a triclinic P - 1 space group with a unit-cell volume of 2203.4(5) Å

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Barrio M, Ceolin R, Robert B, et al. The solid state of anti-inflammatory morniflumate diniflumate: A cocrystalline salt. Int J Pharm. 2021;610:121224doi: 10.1016/j.ijpharm.2021.121224.
Barrio, M., Ceolin, R., Robert, B., Allouchi, H., Teulon, J. M., Guéchot, C., Tamarit, J. L., & Rietveld, I. B. (2021). The solid state of anti-inflammatory morniflumate diniflumate: A cocrystalline salt. International journal of pharmaceutics, 610121224. https://doi.org/10.1016/j.ijpharm.2021.121224
Barrio, Maria, et al. "The solid state of anti-inflammatory morniflumate diniflumate: A cocrystalline salt." International journal of pharmaceutics vol. 610 (2021): 121224. doi: https://doi.org/10.1016/j.ijpharm.2021.121224
Barrio M, Ceolin R, Robert B, Allouchi H, Teulon JM, Guéchot C, Tamarit JL, Rietveld IB. The solid state of anti-inflammatory morniflumate diniflumate: A cocrystalline salt. Int J Pharm. 2021 Dec 15;610:121224. doi: 10.1016/j.ijpharm.2021.121224. Epub 2021 Oct 25. PMID: 34710544.
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Estimation of the ionization pK(a) of pharmaceutical substances using the computer program Sparc.

Talanta

Hilal SH, El-Shabrawy Y, Carreira LA, Karickhoff SW, Toubar SS, Rizk M.
PMID: 18966526
Talanta. 1996 Apr;43(4):607-19. doi: 10.1016/0039-9140(95)01789-5.

The computer program sparc was used to calculate the pK(a) values of some important pharmaceutical substances. The sparc models proved to be suitable for estimating the pK(a) values of beta-adrenergic blocking agents and benzodiazepine drugs. Ionization macroconstants, microconstants, zwitterionic...

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Hilal SH, El-Shabrawy Y, Carreira LA, et al. Estimation of the ionization pK(a) of pharmaceutical substances using the computer program Sparc. Talanta. 1996;43(4):607-19doi: 10.1016/0039-9140(95)01789-5.
Hilal, S. H., El-Shabrawy, Y., Carreira, L. A., Karickhoff, S. W., Toubar, S. S., & Rizk, M. (1996). Estimation of the ionization pK(a) of pharmaceutical substances using the computer program Sparc. Talanta, 43(4), 607-19. https://doi.org/10.1016/0039-9140(95)01789-5
Hilal, S H, et al. "Estimation of the ionization pK(a) of pharmaceutical substances using the computer program Sparc." Talanta vol. 43,4 (1996): 607-19. doi: https://doi.org/10.1016/0039-9140(95)01789-5
Hilal SH, El-Shabrawy Y, Carreira LA, Karickhoff SW, Toubar SS, Rizk M. Estimation of the ionization pK(a) of pharmaceutical substances using the computer program Sparc. Talanta. 1996 Apr;43(4):607-19. doi: 10.1016/0039-9140(95)01789-5. PMID: 18966526.
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Anion-Channel Blockers Inhibit S-Type Anion Channels and Abscisic Acid Responses in Guard Cells.

Plant physiology

Schwartz A, Ilan N, Schwarz M, Scheaffer J, Assmann SM, Schroeder JI.
PMID: 12228619
Plant Physiol. 1995 Oct;109(2):651-658. doi: 10.1104/pp.109.2.651.

The effects of anion-channel blockers on light-mediated stomatal opening, on the potassium dependence of stomatal opening, on stomatal responses to abscisic acid (ABA), and on current through slow anion channels in the plasma membrane of guard cells were investigated....

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Schwartz A, Ilan N, Schwarz M, et al. Anion-Channel Blockers Inhibit S-Type Anion Channels and Abscisic Acid Responses in Guard Cells. Plant Physiol. 1995;109(2):651-658doi: 10.1104/pp.109.2.651.
Schwartz, A., Ilan, N., Schwarz, M., Scheaffer, J., Assmann, S. M., & Schroeder, J. I. (1995). Anion-Channel Blockers Inhibit S-Type Anion Channels and Abscisic Acid Responses in Guard Cells. Plant physiology, 109(2), 651-658. https://doi.org/10.1104/pp.109.2.651
Schwartz, A., et al. "Anion-Channel Blockers Inhibit S-Type Anion Channels and Abscisic Acid Responses in Guard Cells." Plant physiology vol. 109,2 (1995): 651-658. doi: https://doi.org/10.1104/pp.109.2.651
Schwartz A, Ilan N, Schwarz M, Scheaffer J, Assmann SM, Schroeder JI. Anion-Channel Blockers Inhibit S-Type Anion Channels and Abscisic Acid Responses in Guard Cells. Plant Physiol. 1995 Oct;109(2):651-658. doi: 10.1104/pp.109.2.651. PMID: 12228619; PMCID: PMC157632.
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NSAIDs modulate GABA-activated currents via Ca.

Experimental and therapeutic medicine

Zhao L, Li LI, Ma KT, Wang Y, Li J, Shi WY, Zhu HE, Zhang ZS, Si JQ.
PMID: 27168798
Exp Ther Med. 2016 May;11(5):1755-1761. doi: 10.3892/etm.2016.3158. Epub 2016 Mar 15.

The ability of non-steroidal anti-inflammatory drugs (NSAIDs) to modulate γ-aminobutyrate (GABA)-activated currents via Ca

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Zhao L, Li LI, Ma KT, et al. NSAIDs modulate GABA-activated currents via Ca. Exp Ther Med. 2016;11(5):1755-1761doi: 10.3892/etm.2016.3158.
Zhao, L., Li, L. I., Ma, K. T., Wang, Y., Li, J., Shi, W. Y., Zhu, H. E., Zhang, Z. S., & Si, J. Q. (2016). NSAIDs modulate GABA-activated currents via Ca. Experimental and therapeutic medicine, 11(5), 1755-1761. https://doi.org/10.3892/etm.2016.3158
Zhao, Lei, et al. "NSAIDs modulate GABA-activated currents via Ca." Experimental and therapeutic medicine vol. 11,5 (2016): 1755-1761. doi: https://doi.org/10.3892/etm.2016.3158
Zhao L, Li LI, Ma KT, Wang Y, Li J, Shi WY, Zhu HE, Zhang ZS, Si JQ. NSAIDs modulate GABA-activated currents via Ca. Exp Ther Med. 2016 May;11(5):1755-1761. doi: 10.3892/etm.2016.3158. Epub 2016 Mar 15. PMID: 27168798; PMCID: PMC4840517.
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Effects of niflumic acid on γ-aminobutyric acid-induced currents in isolated dorsal root ganglion neurons of neuropathic pain rats.

Experimental and therapeutic medicine

Wang LJ, Wang Y, Chen MJ, Tian ZP, Lu BH, Mao KT, Zhang L, Zhao L, Shan LY, Li L, Si JQ.
PMID: 28810599
Exp Ther Med. 2017 Aug;14(2):1373-1380. doi: 10.3892/etm.2017.4666. Epub 2017 Jun 26.

Niflumic acid (NFA) is a type of non-steroidal anti-inflammatory drug. Neuropathic pain is caused by a decrease in presynaptic inhibition mediated by γ-aminobutyric acid (GABA). In the present study, a whole-cell patch-clamp technique and intracellular recording were used to...

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Wang LJ, Wang Y, Chen MJ, et al. Effects of niflumic acid on γ-aminobutyric acid-induced currents in isolated dorsal root ganglion neurons of neuropathic pain rats. Exp Ther Med. 2017;14(2):1373-1380doi: 10.3892/etm.2017.4666.
Wang, L. J., Wang, Y., Chen, M. J., Tian, Z. P., Lu, B. H., Mao, K. T., Zhang, L., Zhao, L., Shan, L. Y., Li, L., & Si, J. Q. (2017). Effects of niflumic acid on γ-aminobutyric acid-induced currents in isolated dorsal root ganglion neurons of neuropathic pain rats. Experimental and therapeutic medicine, 14(2), 1373-1380. https://doi.org/10.3892/etm.2017.4666
Wang, Li-Jie, et al. "Effects of niflumic acid on γ-aminobutyric acid-induced currents in isolated dorsal root ganglion neurons of neuropathic pain rats." Experimental and therapeutic medicine vol. 14,2 (2017): 1373-1380. doi: https://doi.org/10.3892/etm.2017.4666
Wang LJ, Wang Y, Chen MJ, Tian ZP, Lu BH, Mao KT, Zhang L, Zhao L, Shan LY, Li L, Si JQ. Effects of niflumic acid on γ-aminobutyric acid-induced currents in isolated dorsal root ganglion neurons of neuropathic pain rats. Exp Ther Med. 2017 Aug;14(2):1373-1380. doi: 10.3892/etm.2017.4666. Epub 2017 Jun 26. PMID: 28810599; PMCID: PMC5526125.
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Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate.

Translational and clinical pharmacology

Jin LH, Kim BH, Lee JH, Lee K, Kwack K, Yim SV.
PMID: 32095470
Transl Clin Pharmacol. 2017 Dec;25(4):166-172. doi: 10.12793/tcp.2017.25.4.166. Epub 2017 Dec 20.

Talniflumate is a phthalidyl ester of niflumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis. To screen the possible genetic factors affecting the pharmacokinetics (PK) of talniflumate,...

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Jin LH, Kim BH, Lee JH, et al. Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate. Transl Clin Pharmacol. 2017;25(4):166-172doi: 10.12793/tcp.2017.25.4.166.
Jin, L. H., Kim, B. H., Lee, J. H., Lee, K., Kwack, K., & Yim, S. V. (2017). Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate. Translational and clinical pharmacology, 25(4), 166-172. https://doi.org/10.12793/tcp.2017.25.4.166
Jin, Li Hua, et al. "Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate." Translational and clinical pharmacology vol. 25,4 (2017): 166-172. doi: https://doi.org/10.12793/tcp.2017.25.4.166
Jin LH, Kim BH, Lee JH, Lee K, Kwack K, Yim SV. Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate. Transl Clin Pharmacol. 2017 Dec;25(4):166-172. doi: 10.12793/tcp.2017.25.4.166. Epub 2017 Dec 20. PMID: 32095470; PMCID: PMC7033407.
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Showing 1 to 12 of 35 entries