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Showing 1 to 12 of 30 entries
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Potential for specific dihydropyridine calcium channel blockers to have a positive impact on cognitive function in humans: a systematic review.

Therapeutic advances in chronic disease

Peters J, Booth A, Peters R.
PMID: 26137206
Ther Adv Chronic Dis. 2015 Jul;6(4):160-9. doi: 10.1177/2040622315582353.

BACKGROUND: There is some evidence to suggest a possible association between calcium channel blocker (CCB) use and a lower decline in cognitive function compared with use of other hypertensive treatments. In particular, there is an emerging interest in the...

Antihypertensive therapy in older patients with isolated systolic hypertension: the Syst-Eur experience in general practice.

Family practice

Celis H, Yodfat Y, Thijs L, Clement D, Cozic J, De Cort P, Forette F, Gregoire M, Heyrman J, Stibbe G, Van den Haute M, Staessen J, Fagard R, behalf of the Syst-Eur Investigators o.
PMID: 8671117
Fam Pract. 1996;13(2):138-43.

Background and objective. This interim report from the Syst-Eur trial investigated the level of blood pressure control achieved during the double-blind period in patients followed in general practices. Methods. In the Syst-Eur trial elderly patients (60 years or older)...

How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2).

Current controlled trials in cardiovascular medicine

Thijs L, Staessen JA, Beleva S, Birkenhäger WH, Bulpitt CJ, Celis H, Fletcher AE, Kermova R, Leonetti G, Laks T, Mantov S, Nachev C, Sarti C, Tuomilehto J, Fagard RH.
PMID: 11806817
Curr Control Trials Cardiovasc Med. 2001 Oct 18;2(6):298-306. doi: 10.1186/cvm-2-6-298.

BACKGROUND: The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy starting with nitrendipine reduces the risk of cardiovascular complications in elderly patients with isolated systolic hypertension. In an attempt to...

Selective enhancement in striatal [(3)H]nitrendipine binding following chronic treatment with morphine.

Neurochemistry international

Saito K, Ishii K, Fujita N, Nakahiro M, Inoki R.
PMID: 20493016
Neurochem Int. 1985;7(6):1033-6. doi: 10.1016/0197-0186(85)90152-4.

Two parameters of Ca(2+) dynamics in brain preparations ((45)Ca-uptake to slices and [(3)H]nitrendipine binding to membrane fractions) were measured in naive and chronic morphine-administered rats. While morphine did not have any effect on (45)Ca-uptake to striatal slices in normal...

Long-term habituation of the gill-withdrawal reflex in aplysia requires gene transcription, calcineurin and L-type voltage-gated calcium channels.

Frontiers in behavioral neuroscience

Esdin J, Pearce K, Glanzman DL.
PMID: 21152260
Front Behav Neurosci. 2010 Nov 29;4:181. doi: 10.3389/fnbeh.2010.00181. eCollection 2010.

Although habituation is possibly the simplest form of learning, we still do not fully understand the neurobiological basis of habituation in any organism. To advance the goal of a comprehensive understanding of habituation, we have studied long-term habituation (LTH)...

Nitrendipine and Dementia: Forgotten Positive Facts?.

Frontiers in aging neuroscience

Novotny M, Klimova B, Valis M.
PMID: 30618724
Front Aging Neurosci. 2018 Dec 18;10:418. doi: 10.3389/fnagi.2018.00418. eCollection 2018.

Nowadays, there are about 50 million people suffering from dementia worldwide. In 2030, it is expected that there will be 82 million people living with dementia and in 2050, their number should reach 152 million. This increase in the...

Nitrendipine-Treatment Increases Cork Spot Disorder Incidence in Pear 'Akituki' (.

Plants (Basel, Switzerland)

Cui Z, Wang N, Li D, Wang R, Ma C.
PMID: 34067594
Plants (Basel). 2021 May 17;10(5). doi: 10.3390/plants10050994.

'Akituki' (

Pharmacological properties of voltage-gated Na+ currents in motor neurones from a hydrozoan jellyfish Polyorchis penicillatus.

The Journal of experimental biology

Spafford J, Grigoriev N, Spencer A.
PMID: 9318735
J Exp Biol. 1996;199:941-8.

The Na+ current of 'swimming motor neurones' in the hydromedusan Polyorchis penicillatus was tetrodotoxin-insensitive. The local anaesthetics lidocaine and procainamide caused partial, non use-dependent blockade of the Na+ channel. Veratridine produced partial blockade of the Na+ channel without affecting...

The Effect of Hypertension Treatment on the Prevention of Coronary Artery Disease Events in the Elderly.

The American journal of geriatric cardiology

Moser M.
PMID: 11416442
Am J Geriatr Cardiol. 1998 Jan;7(1):28-34.

Both isolated systolic (greater than 140/ less than 90 mm Hg) and systolic/diastolic ( greater than 140/ greater than 90 mm Hg) hypertension have been identified as major risk factors for cardiovascular disease in the elderly. Effective specific antihypertension...

Inhibition of lipid peroxidation by some dihydropyridine derivatives.

Journal of anesthesia

Sakamoto A, Ohnishi ST, Ogawa R.
PMID: 15278473
J Anesth. 1993 Apr;7(2):193-7. doi: 10.1007/s0054030070193.

The efficacy of dihydropyridine derivatives in inhibiting lipid peroxidation was studied using modified Buege and Aust's method. The method first involves keeping a decapitated rat head at 37 degrees C for 30 min in order to induce global ischemia....

Role of multiple voltage-sensitive calcium channels in depolarization-induced release of neuropeptide y and luteinizing hormone-releasing hormone from rat median eminence-arcuate nucleus.

Molecular and cellular neurosciences

Sahu A, Crowley WR, Kalra SP, Kalra PS.
PMID: 19912956
Mol Cell Neurosci. 1993 Dec;4(6):492-8. doi: 10.1006/mcne.1993.1061.

The objective of the present studies was to identify the subtypes of voltage-sensitive Ca(2+) channels (VSCC) that regulate the basal and depolarization-induced release of neuropeptide Y (NPY) and LH-releasing hormone (LHRH) from rat hypothalamus. Tissues containing median eminence-arcuate nucleus...

Morbidity and mortality after stroke--eposartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES).

Current cardiology reports

Weinberger J.
PMID: 17362677
Curr Cardiol Rep. 2007 Mar;9(1):5.

No abstract available.

Showing 1 to 12 of 30 entries