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Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.

Toxicological research

Shimada T.
PMID: 28443179
Toxicol Res. 2017 Apr;33(2):79-96. doi: 10.5487/TR.2017.33.2.079. Epub 2017 Apr 15.

A variety of xenobiotic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), aryl- and heterocyclic amines and tobacco related nitrosamines, are ubiquitous environmental carcinogens and are required to be activated to chemically reactive metabolites by xenobiotic-metabolizing enzymes, including cytochrome P450...

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Shimada T. Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity. Toxicol Res. 2017;33(2):79-96doi: 10.5487/TR.2017.33.2.079.
Shimada, T. (2017). Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity. Toxicological research, 33(2), 79-96. https://doi.org/10.5487/TR.2017.33.2.079
Shimada, Tsutomu. "Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity." Toxicological research vol. 33,2 (2017): 79-96. doi: https://doi.org/10.5487/TR.2017.33.2.079
Shimada T. Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity. Toxicol Res. 2017 Apr;33(2):79-96. doi: 10.5487/TR.2017.33.2.079. Epub 2017 Apr 15. PMID: 28443179; PMCID: PMC5402866.
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Facilely Fabricating Multifunctional N-Enriched Carbon.

ACS applied materials & interfaces

Wan MM, Sun XD, Li YY, Zhou J, Wang Y, Zhu JH.
PMID: 26700796
ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1252-63. doi: 10.1021/acsami.5b09759. Epub 2016 Jan 07.

A new synthetic strategy, named "carbonization in limited space" and based on the specific interaction between eutectic salt and dual-ionic liquids (dual-ILs), is reported in this article. N-Containing dual-ILs (1,4-diethyl-1,4-diazaniabicyclo[2,2,2]octane imidazolide-4,5-dicyanoiazolide, [2C2DABCO](2+)[Im](-)[CN-Im](-)) were synthesized as new carbon-nitrogen precursors, while...

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Wan MM, Sun XD, Li YY, et al. Facilely Fabricating Multifunctional N-Enriched Carbon. ACS Appl Mater Interfaces. 2016;8(2):1252-63doi: 10.1021/acsami.5b09759.
Wan, M. M., Sun, X. D., Li, Y. Y., Zhou, J., Wang, Y., & Zhu, J. H. (2016). Facilely Fabricating Multifunctional N-Enriched Carbon. ACS applied materials & interfaces, 8(2), 1252-63. https://doi.org/10.1021/acsami.5b09759
Wan, Mi Mi, et al. "Facilely Fabricating Multifunctional N-Enriched Carbon." ACS applied materials & interfaces vol. 8,2 (2016): 1252-63. doi: https://doi.org/10.1021/acsami.5b09759
Wan MM, Sun XD, Li YY, Zhou J, Wang Y, Zhu JH. Facilely Fabricating Multifunctional N-Enriched Carbon. ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1252-63. doi: 10.1021/acsami.5b09759. Epub 2016 Jan 07. PMID: 26700796.
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Distribution of Seven N-Nitrosamines in Food.

Toxicological research

Park JE, Seo JE, Lee JY, Kwon H.
PMID: 26483887
Toxicol Res. 2015 Sep;31(3):279-88. doi: 10.5487/TR.2015.31.3.279.

N-nitrosamines, which are classified as carcinogens by IARC and US EPA, can be easily found in various foods. They are reaction products between nitrogen oxide and secondary amines, but can also be generated during fermentation. Ever since the 1960s,...

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Park JE, Seo JE, Lee JY, et al. Distribution of Seven N-Nitrosamines in Food. Toxicol Res. 2015;31(3):279-88doi: 10.5487/TR.2015.31.3.279.
Park, J. E., Seo, J. E., Lee, J. Y., & Kwon, H. (2015). Distribution of Seven N-Nitrosamines in Food. Toxicological research, 31(3), 279-88. https://doi.org/10.5487/TR.2015.31.3.279
Park, Jong-Eun, et al. "Distribution of Seven N-Nitrosamines in Food." Toxicological research vol. 31,3 (2015): 279-88. doi: https://doi.org/10.5487/TR.2015.31.3.279
Park JE, Seo JE, Lee JY, Kwon H. Distribution of Seven N-Nitrosamines in Food. Toxicol Res. 2015 Sep;31(3):279-88. doi: 10.5487/TR.2015.31.3.279. PMID: 26483887; PMCID: PMC4609975.
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Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A Review.

Frontiers in oncology

Sanner T, Grimsrud TK.
PMID: 26380225
Front Oncol. 2015 Aug 31;5:196. doi: 10.3389/fonc.2015.00196. eCollection 2015.

Tobacco use is considered the single most important man-made cause of cancer that can be avoided. The evidence that nicotine is involved in cancer development is reviewed and discussed in this paper. Both tobacco smoke and tobacco products for...

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Sanner T, Grimsrud TK. Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A Review. Front Oncol. 2015;5:196doi: 10.3389/fonc.2015.00196.
Sanner, T., & Grimsrud, T. K. (2015). Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A Review. Frontiers in oncology, 5196. https://doi.org/10.3389/fonc.2015.00196
Sanner, Tore, and Grimsrud, Tom K. "Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A Review." Frontiers in oncology vol. 5 (2015): 196. doi: https://doi.org/10.3389/fonc.2015.00196
Sanner T, Grimsrud TK. Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A Review. Front Oncol. 2015 Aug 31;5:196. doi: 10.3389/fonc.2015.00196. eCollection 2015. PMID: 26380225; PMCID: PMC4553893.
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Synthesis and characterization of secondary nitrosamines from secondary amines using sodium nitrite and p-toluenesulfonic acid.

Chemistry, an Asian journal

Miró Sabaté C, Delalu H.
PMID: 25582458
Chem Asian J. 2015 Mar;10(3):674-8. doi: 10.1002/asia.201403182. Epub 2015 Jan 12.

We synthesized nitrosamines (R2N-NO) with R = iPr (1), nPr (2), nBu (3), and hydroxyethyl (4) from the amine using sodium nitrite/p-toluenesulfonic acid in CH2Cl2. The rate of formation of 1-4 increases in the direction iPr

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Miró Sabaté C, Delalu H. Synthesis and characterization of secondary nitrosamines from secondary amines using sodium nitrite and p-toluenesulfonic acid. Chem Asian J. 2015;10(3):674-8doi: 10.1002/asia.201403182.
Miró Sabaté, C., & Delalu, H. (2015). Synthesis and characterization of secondary nitrosamines from secondary amines using sodium nitrite and p-toluenesulfonic acid. Chemistry, an Asian journal, 10(3), 674-8. https://doi.org/10.1002/asia.201403182
Miró Sabaté, Carles, and Delalu, Henri. "Synthesis and characterization of secondary nitrosamines from secondary amines using sodium nitrite and p-toluenesulfonic acid." Chemistry, an Asian journal vol. 10,3 (2015): 674-8. doi: https://doi.org/10.1002/asia.201403182
Miró Sabaté C, Delalu H. Synthesis and characterization of secondary nitrosamines from secondary amines using sodium nitrite and p-toluenesulfonic acid. Chem Asian J. 2015 Mar;10(3):674-8. doi: 10.1002/asia.201403182. Epub 2015 Jan 12. PMID: 25582458.
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Anaerobic (bacterial) vaginosis and premalignant disease of the cervix.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Barrington JW, Linton D, O'Leary A, Blackwell A, Brick J, Calvert JP.
PMID: 15511897
J Obstet Gynaecol. 1997 Jun;17(4):383-5. doi: 10.1080/01443619750112943.

Nitrosamines are carcinogenic substances found in cigarette smoke, and it is known that female smokers have an increased risk of cervical carcinoma and premalignant change. Nitrosamines may also be formed due to the combination of amines and nitrites in...

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Barrington JW, Linton D, O'Leary A, et al. Anaerobic (bacterial) vaginosis and premalignant disease of the cervix. J Obstet Gynaecol. 1997;17(4):383-5doi: 10.1080/01443619750112943.
Barrington, J. W., Linton, D., O'Leary, A., Blackwell, A., Brick, J., & Calvert, J. P. (1997). Anaerobic (bacterial) vaginosis and premalignant disease of the cervix. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 17(4), 383-5. https://doi.org/10.1080/01443619750112943
Barrington, J W, et al. "Anaerobic (bacterial) vaginosis and premalignant disease of the cervix." Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology vol. 17,4 (1997): 383-5. doi: https://doi.org/10.1080/01443619750112943
Barrington JW, Linton D, O'Leary A, Blackwell A, Brick J, Calvert JP. Anaerobic (bacterial) vaginosis and premalignant disease of the cervix. J Obstet Gynaecol. 1997 Jun;17(4):383-5. doi: 10.1080/01443619750112943. PMID: 15511897.
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Significance of nitrosamines in animal diets.

Science (New York, N.Y.)

Edwards GS, Fox JG.
PMID: 17840491
Science. 1979 Jan 05;203(4375):6. doi: 10.1126/science.203.4375.6.

No abstract available.

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Edwards GS, Fox JG. Significance of nitrosamines in animal diets. Science. 1979;203(4375):6doi: 10.1126/science.203.4375.6.
Edwards, G. S., & Fox, J. G. (1979). Significance of nitrosamines in animal diets. Science (New York, N.Y.), 203(4375), 6. https://doi.org/10.1126/science.203.4375.6
Edwards, G S, and Fox, J G. "Significance of nitrosamines in animal diets." Science (New York, N.Y.) vol. 203,4375 (1979): 6. doi: https://doi.org/10.1126/science.203.4375.6
Edwards GS, Fox JG. Significance of nitrosamines in animal diets. Science. 1979 Jan 05;203(4375):6. doi: 10.1126/science.203.4375.6. PMID: 17840491.
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Chemical ionization mass spectrometry of nitrosamines.

Talanta

Fang Y, Jiahua D, Shili L.
PMID: 18963662
Talanta. 1984 Aug;31(8):619-20. doi: 10.1016/0039-9140(84)80181-2.

The mass spectra of eight nitrosamines have been recorded, with excitation by chemical ionization (CI) and electron impact (EI). Comparison of the intensities of the base peaks under CI and El conditions gives intensity ratios in the range 1.4-1.9...

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Fang Y, Jiahua D, Shili L. Chemical ionization mass spectrometry of nitrosamines. Talanta. 1984;31(8):619-20doi: 10.1016/0039-9140(84)80181-2.
Fang, Y., Jiahua, D., & Shili, L. (1984). Chemical ionization mass spectrometry of nitrosamines. Talanta, 31(8), 619-20. https://doi.org/10.1016/0039-9140(84)80181-2
Fang, Y, et al. "Chemical ionization mass spectrometry of nitrosamines." Talanta vol. 31,8 (1984): 619-20. doi: https://doi.org/10.1016/0039-9140(84)80181-2
Fang Y, Jiahua D, Shili L. Chemical ionization mass spectrometry of nitrosamines. Talanta. 1984 Aug;31(8):619-20. doi: 10.1016/0039-9140(84)80181-2. PMID: 18963662.
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Formation and repair of tobacco carcinogen-derived bulky DNA adducts.

Journal of nucleic acids

Hang B.
PMID: 21234336
J Nucleic Acids. 2010 Dec 20;2010:709521. doi: 10.4061/2010/709521.

DNA adducts play a central role in chemical carcinogenesis. The analysis of formation and repair of smoking-related DNA adducts remains particularly challenging as both smokers and nonsmokers exposed to smoke are repetitively under attack from complex mixtures of carcinogens...

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Hang B. Formation and repair of tobacco carcinogen-derived bulky DNA adducts. J Nucleic Acids. 2010;2010:709521doi: 10.4061/2010/709521.
Hang, B. (2010). Formation and repair of tobacco carcinogen-derived bulky DNA adducts. Journal of nucleic acids, 2010709521. https://doi.org/10.4061/2010/709521
Hang, Bo. "Formation and repair of tobacco carcinogen-derived bulky DNA adducts." Journal of nucleic acids vol. 2010 (2010): 709521. doi: https://doi.org/10.4061/2010/709521
Hang B. Formation and repair of tobacco carcinogen-derived bulky DNA adducts. J Nucleic Acids. 2010 Dec 20;2010:709521. doi: 10.4061/2010/709521. PMID: 21234336; PMCID: PMC3017938.
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Automatic screening method for the preconcentration and determination of N-nitrosamines in water.

Talanta

Jurado-Sánchez B, Ballesteros E, Gallego M.
PMID: 19073062
Talanta. 2007 Sep 30;73(3):498-504. doi: 10.1016/j.talanta.2007.04.007. Epub 2007 Apr 21.

A screening method was developed to discriminate among water samples contaminated or uncontaminated with N-nitrosamines in order to reduce the use of expensive instruments such as chromatographs. The system is based on the preconcentration of the analytes onto a...

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Jurado-Sánchez B, Ballesteros E, Gallego M. Automatic screening method for the preconcentration and determination of N-nitrosamines in water. Talanta. 2007;73(3):498-504doi: 10.1016/j.talanta.2007.04.007.
Jurado-Sánchez, B., Ballesteros, E., & Gallego, M. (2007). Automatic screening method for the preconcentration and determination of N-nitrosamines in water. Talanta, 73(3), 498-504. https://doi.org/10.1016/j.talanta.2007.04.007
Jurado-Sánchez, Beatriz, et al. "Automatic screening method for the preconcentration and determination of N-nitrosamines in water." Talanta vol. 73,3 (2007): 498-504. doi: https://doi.org/10.1016/j.talanta.2007.04.007
Jurado-Sánchez B, Ballesteros E, Gallego M. Automatic screening method for the preconcentration and determination of N-nitrosamines in water. Talanta. 2007 Sep 30;73(3):498-504. doi: 10.1016/j.talanta.2007.04.007. Epub 2007 Apr 21. PMID: 19073062.
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A screening procedure for total N-nitroso contaminants in personal care products: results of collaborative studies undertaken by a CTPA Working Group.

International journal of cosmetic science

Challis BC, Colling J, Cromie DD, Guthrie WG, Pollock JR, Taylor P, Telling GM, Wallace L.
PMID: 19245470
Int J Cosmet Sci. 1995 Dec;17(6):219-31. doi: 10.1111/j.1467-2494.1995.tb00127.x.

Synopsis A modified procedure for the determination of total N-nitroso compounds in personal care products was evaluated in collaborative studies organized through the UK Cosmetic Toiletry and Perfumery Association (CTPA). The method offers a true 'totals'determination in that a...

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Challis BC, Colling J, Cromie DD, et al. A screening procedure for total N-nitroso contaminants in personal care products: results of collaborative studies undertaken by a CTPA Working Group. Int J Cosmet Sci. 1995;17(6):219-31doi: 10.1111/j.1467-2494.1995.tb00127.x.
Challis, B. C., Colling, J., Cromie, D. D., Guthrie, W. G., Pollock, J. R., Taylor, P., Telling, G. M., & Wallace, L. (1995). A screening procedure for total N-nitroso contaminants in personal care products: results of collaborative studies undertaken by a CTPA Working Group. International journal of cosmetic science, 17(6), 219-31. https://doi.org/10.1111/j.1467-2494.1995.tb00127.x
Challis, B C, et al. "A screening procedure for total N-nitroso contaminants in personal care products: results of collaborative studies undertaken by a CTPA Working Group." International journal of cosmetic science vol. 17,6 (1995): 219-31. doi: https://doi.org/10.1111/j.1467-2494.1995.tb00127.x
Challis BC, Colling J, Cromie DD, Guthrie WG, Pollock JR, Taylor P, Telling GM, Wallace L. A screening procedure for total N-nitroso contaminants in personal care products: results of collaborative studies undertaken by a CTPA Working Group. Int J Cosmet Sci. 1995 Dec;17(6):219-31. doi: 10.1111/j.1467-2494.1995.tb00127.x. PMID: 19245470.
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Reduction of nitrosamines in cosmetic products.

International journal of cosmetic science

Challis BC, Trew DF, Guthrie WG, Roper DV.
PMID: 19245496
Int J Cosmet Sci. 1995 Jun;17(3):119-31. doi: 10.1111/j.1467-2494.1995.tb00115.x.

Summary From initial rate studies of morpholine nitrosation in aqueous media by nitrite ion in the presence of formaldehyde at pH 5-7 and 25 degrees C, four potential pathways are revealed for the concurrent formation of nitrosamine contaminants in...

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Challis BC, Trew DF, Guthrie WG, et al. Reduction of nitrosamines in cosmetic products. Int J Cosmet Sci. 1995;17(3):119-31doi: 10.1111/j.1467-2494.1995.tb00115.x.
Challis, B. C., Trew, D. F., Guthrie, W. G., & Roper, D. V. (1995). Reduction of nitrosamines in cosmetic products. International journal of cosmetic science, 17(3), 119-31. https://doi.org/10.1111/j.1467-2494.1995.tb00115.x
Challis, B C, et al. "Reduction of nitrosamines in cosmetic products." International journal of cosmetic science vol. 17,3 (1995): 119-31. doi: https://doi.org/10.1111/j.1467-2494.1995.tb00115.x
Challis BC, Trew DF, Guthrie WG, Roper DV. Reduction of nitrosamines in cosmetic products. Int J Cosmet Sci. 1995 Jun;17(3):119-31. doi: 10.1111/j.1467-2494.1995.tb00115.x. PMID: 19245496.
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Showing 1 to 12 of 300 entries