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Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats.

Cardiovascular endocrinology

Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI.
PMID: 23795309
Cardiovasc Endocrinol. 2012 Sep 01;1(3):49-58. doi: 10.1097/XCE.0b013e32835a2159.

OBJECTIVES: Long-term systemic blockade of the renin-angiotensin system (RAS) with either an angiotensin (Ang) II type 1 receptor antagonist or an angiotensin-converting enzyme inhibitor attenuates age-related cardiac remodeling and oxidative damage, and improves myocardial relaxation. However, the role of...

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Groban L, Wang H, Machado FS, et al. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012;1(3):49-58doi: 10.1097/XCE.0b013e32835a2159.
Groban, L., Wang, H., Machado, F. S., Trask, A. J., Kritchevsky, S. B., Ferrario, C. M., & Diz, D. I. (2012). Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovascular endocrinology, 1(3), 49-58. https://doi.org/10.1097/XCE.0b013e32835a2159
Groban, Leanne, et al. "Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats." Cardiovascular endocrinology vol. 1,3 (2012): 49-58. doi: https://doi.org/10.1097/XCE.0b013e32835a2159
Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012 Sep 01;1(3):49-58. doi: 10.1097/XCE.0b013e32835a2159. PMID: 23795309; PMCID: PMC3685869.
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Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults.

BMC obesity

Bharadwaj MS, Tyrrell DJ, Leng I, Demons JL, Lyles MF, Carr JJ, Nicklas BJ, Molina AJ.
PMID: 26448868
BMC Obes. 2015 Oct 06;2:40. doi: 10.1186/s40608-015-0070-4. eCollection 2015.

BACKGROUND: Mitochondrial function declines with age; however, the relationship between adiposity and mitochondrial function among older adults is unclear. This study examined relationships between skeletal muscle mitochondrial content and electron transport chain complex 2 driven respiration with whole body...

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Bharadwaj MS, Tyrrell DJ, Leng I, et al. Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults. BMC Obes. 2015;2:40doi: 10.1186/s40608-015-0070-4.
Bharadwaj, M. S., Tyrrell, D. J., Leng, I., Demons, J. L., Lyles, M. F., Carr, J. J., Nicklas, B. J., & Molina, A. J. (2015). Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults. BMC obesity, 240. https://doi.org/10.1186/s40608-015-0070-4
Bharadwaj, Manish S, et al. "Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults." BMC obesity vol. 2 (2015): 40. doi: https://doi.org/10.1186/s40608-015-0070-4
Bharadwaj MS, Tyrrell DJ, Leng I, Demons JL, Lyles MF, Carr JJ, Nicklas BJ, Molina AJ. Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults. BMC Obes. 2015 Oct 06;2:40. doi: 10.1186/s40608-015-0070-4. eCollection 2015. PMID: 26448868; PMCID: PMC4594906.
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Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia.

Current gerontology and geriatrics research

Vaughan L, Leng I, Dagenbach D, Resnick SM, Rapp SR, Jennings JM, Brunner RL, Simpson SL, Beavers DP, Coker LH, Gaussoin SA, Sink KM, Espeland MA.
PMID: 24454359
Curr Gerontol Geriatr Res. 2013;2013:495793. doi: 10.1155/2013/495793. Epub 2013 Dec 22.

Intraindividual variability among cognitive domains may predict dementia independently of interindividual differences in cognition. A multidomain cognitive battery was administered to 2305 older adult women (mean age 74 years) enrolled in an ancillary study of the Women's Health Initiative....

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Vaughan L, Leng I, Dagenbach D, et al. Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia. Curr Gerontol Geriatr Res. 2013;2013:495793doi: 10.1155/2013/495793.
Vaughan, L., Leng, I., Dagenbach, D., Resnick, S. M., Rapp, S. R., Jennings, J. M., Brunner, R. L., Simpson, S. L., Beavers, D. P., Coker, L. H., Gaussoin, S. A., Sink, K. M., & Espeland, M. A. (2013). Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia. Current gerontology and geriatrics research, 2013495793. https://doi.org/10.1155/2013/495793
Vaughan, Leslie, et al. "Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia." Current gerontology and geriatrics research vol. 2013 (2013): 495793. doi: https://doi.org/10.1155/2013/495793
Vaughan L, Leng I, Dagenbach D, Resnick SM, Rapp SR, Jennings JM, Brunner RL, Simpson SL, Beavers DP, Coker LH, Gaussoin SA, Sink KM, Espeland MA. Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia. Curr Gerontol Geriatr Res. 2013;2013:495793. doi: 10.1155/2013/495793. Epub 2013 Dec 22. PMID: 24454359; PMCID: PMC3881440.
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Exercise intolerance.

Cardiology clinics

Kitzman DW, Groban L.
PMID: 21803233
Cardiol Clin. 2011 Aug;29(3):461-77. doi: 10.1016/j.ccl.2011.06.002.

Exercise intolerance is the primary symptom of chronic diastolic heart failure. It is part of the definition of heart failure and is intimately linked to its pathophysiology. Further, exercise intolerance affects the diagnosis and prognosis of heart failure. In...

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Kitzman DW, Groban L. Exercise intolerance. Cardiol Clin. 2011;29(3):461-77doi: 10.1016/j.ccl.2011.06.002.
Kitzman, D. W., & Groban, L. (2011). Exercise intolerance. Cardiology clinics, 29(3), 461-77. https://doi.org/10.1016/j.ccl.2011.06.002
Kitzman, Dalane W, and Groban, Leanne. "Exercise intolerance." Cardiology clinics vol. 29,3 (2011): 461-77. doi: https://doi.org/10.1016/j.ccl.2011.06.002
Kitzman DW, Groban L. Exercise intolerance. Cardiol Clin. 2011 Aug;29(3):461-77. doi: 10.1016/j.ccl.2011.06.002. PMID: 21803233; PMCID: PMC3694583.
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Patient-Reported Outcome Measures (PROM) as A Preoperative Assessment Tool.

Journal of anesthesia and perioperative medicine

Kim S, Duncan PW, Groban L, Segal H, Abbott RM, Williamson JD.
PMID: 29333531
J Anesth Perioper Med. 2017 Nov 28;4(6):274-281. Epub 2017 Nov 02.

AIM OF REVIEW: Patient-reported outcomes (PRO) on functional, social, and behavioral factors might be important preoperative predictors of postoperative outcomes. We conducted a literature review to explore associations of preoperative depression, socioeconomic status, social support, functional status/frailty, cognitive status,...

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Kim S, Duncan PW, Groban L, et al. Patient-Reported Outcome Measures (PROM) as A Preoperative Assessment Tool. J Anesth Perioper Med. 2017;4(6):274-281
Kim, S., Duncan, P. W., Groban, L., Segal, H., Abbott, R. M., & Williamson, J. D. (2017). Patient-Reported Outcome Measures (PROM) as A Preoperative Assessment Tool. Journal of anesthesia and perioperative medicine, 4(6), 274-281.
Kim, Sunghye, et al. "Patient-Reported Outcome Measures (PROM) as A Preoperative Assessment Tool." Journal of anesthesia and perioperative medicine vol. 4,6 (2017): 274-281.
Kim S, Duncan PW, Groban L, Segal H, Abbott RM, Williamson JD. Patient-Reported Outcome Measures (PROM) as A Preoperative Assessment Tool. J Anesth Perioper Med. 2017 Nov 28;4(6):274-281. Epub 2017 Nov 02. PMID: 29333531; PMCID: PMC5766034.
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Weighted Vest Use during Dietary Weight Loss on Bone Health in Older Adults with Obesity.

Journal of osteoporosis and physical activity

Kelleher JL, Beavers DP, Henderson RM, Yow D, Crotts C, Kiel J, Nicklas BJ, Beavers KM.
PMID: 29388604
J Osteoporos Phys Act. 2017;5(4). doi: 10.4172/2329-9509.1000210. Epub 2017 Nov 28.

BACKGROUND: To examine the effects of daily weighted vest use during a dietary weight loss intervention, on (a) hip and spine bone mineral density (aBMD), and (b) biomarkers of bone turnover, in older adults with obesity.METHODS: 37 older (70.1...

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Kelleher JL, Beavers DP, Henderson RM, et al. Weighted Vest Use during Dietary Weight Loss on Bone Health in Older Adults with Obesity. J Osteoporos Phys Act. 2017;5(4)doi: 10.4172/2329-9509.1000210.
Kelleher, J. L., Beavers, D. P., Henderson, R. M., Yow, D., Crotts, C., Kiel, J., Nicklas, B. J., & Beavers, K. M. (2017). Weighted Vest Use during Dietary Weight Loss on Bone Health in Older Adults with Obesity. Journal of osteoporosis and physical activity, 5(4), . https://doi.org/10.4172/2329-9509.1000210
Kelleher, Jessica L, et al. "Weighted Vest Use during Dietary Weight Loss on Bone Health in Older Adults with Obesity." Journal of osteoporosis and physical activity vol. 5,4 (2017). doi: https://doi.org/10.4172/2329-9509.1000210
Kelleher JL, Beavers DP, Henderson RM, Yow D, Crotts C, Kiel J, Nicklas BJ, Beavers KM. Weighted Vest Use during Dietary Weight Loss on Bone Health in Older Adults with Obesity. J Osteoporos Phys Act. 2017;5(4). doi: 10.4172/2329-9509.1000210. Epub 2017 Nov 28. PMID: 29388604; PMCID: PMC5788462.
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Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle.

Frontiers in aging neuroscience

Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.
PMID: 25278877
Front Aging Neurosci. 2014 Sep 18;6:245. doi: 10.3389/fnagi.2014.00245. eCollection 2014.

Pericytes are perivascular cells that envelop and make intimate connections with adjacent capillary endothelial cells. Recent studies show that they may have a profound impact in skeletal muscle regeneration, innervation, vessel formation, fibrosis, fat accumulation, and ectopic bone formation...

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Birbrair A, Zhang T, Wang ZM, et al. Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Front Aging Neurosci. 2014;6:245doi: 10.3389/fnagi.2014.00245.
Birbrair, A., Zhang, T., Wang, Z. M., Messi, M. L., Mintz, A., & Delbono, O. (2014). Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Frontiers in aging neuroscience, 6245. https://doi.org/10.3389/fnagi.2014.00245
Birbrair, Alexander, et al. "Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle." Frontiers in aging neuroscience vol. 6 (2014): 245. doi: https://doi.org/10.3389/fnagi.2014.00245
Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O. Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Front Aging Neurosci. 2014 Sep 18;6:245. doi: 10.3389/fnagi.2014.00245. eCollection 2014. PMID: 25278877; PMCID: PMC4166895.
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Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults.

Frontiers in aging neuroscience

Wanigatunga AA, Manini TM, Cook DR, Katula J, Fielding RA, Kramer AF, Verghese J, Rapp SR, Sink KM, King AC, Buford TW, Anton S, Nadkarni N, Jennings JM, Reid K, Espeland MA, Gill TM, Pahor M, Nocera JR.
PMID: 30498440
Front Aging Neurosci. 2018 Nov 15;10:341. doi: 10.3389/fnagi.2018.00341. eCollection 2018.

Over the last few decades, considerable evidence shows that greater levels of aerobic exercise and cardiovascular fitness benefit cognitive performance. However, the degree to which free-living activity in community settings is related to cognitive performance remains unclear, particularly in...

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Wanigatunga AA, Manini TM, Cook DR, et al. Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci. 2018;10:341doi: 10.3389/fnagi.2018.00341.
Wanigatunga, A. A., Manini, T. M., Cook, D. R., Katula, J., Fielding, R. A., Kramer, A. F., Verghese, J., Rapp, S. R., Sink, K. M., King, A. C., Buford, T. W., Anton, S., Nadkarni, N., Jennings, J. M., Reid, K., Espeland, M. A., Gill, T. M., Pahor, M., & Nocera, J. R. (2018). Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Frontiers in aging neuroscience, 10341. https://doi.org/10.3389/fnagi.2018.00341
Wanigatunga, Amal A, et al. "Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults." Frontiers in aging neuroscience vol. 10 (2018): 341. doi: https://doi.org/10.3389/fnagi.2018.00341
Wanigatunga AA, Manini TM, Cook DR, Katula J, Fielding RA, Kramer AF, Verghese J, Rapp SR, Sink KM, King AC, Buford TW, Anton S, Nadkarni N, Jennings JM, Reid K, Espeland MA, Gill TM, Pahor M, Nocera JR. Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci. 2018 Nov 15;10:341. doi: 10.3389/fnagi.2018.00341. eCollection 2018. PMID: 30498440; PMCID: PMC6249499.
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Serious adverse events of older adults in nursing home and community intervention trials.

Contemporary clinical trials communications

Datta R, Trentalange M, Van Ness PH, McGloin JM, Guralnik JM, Miller ME, Walkup MP, Nadkarni N, Pahor M, Gill TM, Quagliarello V, Juthani-Mehta M.
PMID: 29696228
Contemp Clin Trials Commun. 2017 Dec 21;9:77-80. doi: 10.1016/j.conctc.2017.12.004. eCollection 2018 Mar.

BACKGROUND/AIMS: Clinical trials of older adults are increasingly common, but risks of serious adverse events (SAE) may vary. We describe the incidence of SAE in two randomized trials, one community-based and one nursing home-based.METHODS: We performed a secondary data...

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Datta R, Trentalange M, Van Ness PH, et al. Serious adverse events of older adults in nursing home and community intervention trials. Contemp Clin Trials Commun. 2017;9:77-80doi: 10.1016/j.conctc.2017.12.004.
Datta, R., Trentalange, M., Van Ness, P. H., McGloin, J. M., Guralnik, J. M., Miller, M. E., Walkup, M. P., Nadkarni, N., Pahor, M., Gill, T. M., Quagliarello, V., Juthani-Mehta, M. (2018). Serious adverse events of older adults in nursing home and community intervention trials. Contemporary clinical trials communications, 977-80. https://doi.org/10.1016/j.conctc.2017.12.004
Datta, Rupak, et al. "Serious adverse events of older adults in nursing home and community intervention trials." Contemporary clinical trials communications vol. 9 (2018): 77-80. doi: https://doi.org/10.1016/j.conctc.2017.12.004
Datta R, Trentalange M, Van Ness PH, McGloin JM, Guralnik JM, Miller ME, Walkup MP, Nadkarni N, Pahor M, Gill TM, Quagliarello V, Juthani-Mehta M. Serious adverse events of older adults in nursing home and community intervention trials. Contemp Clin Trials Commun. 2017 Dec 21;9:77-80. doi: 10.1016/j.conctc.2017.12.004. eCollection 2018 Mar. PMID: 29696228; PMCID: PMC5898490.
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Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice.

Journal of cachexia, sarcopenia and muscle

Rodrigues ACZ, Messi ML, Wang ZM, Bonilla HJ, Freeman WM, Delbono O.
PMID: 34546662
J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1908-1924. doi: 10.1002/jcsm.12790. Epub 2021 Sep 21.

BACKGROUND: The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass. However, chronic administration has serious side effects...

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Rodrigues ACZ, Messi ML, Wang ZM, et al. Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice. J Cachexia Sarcopenia Muscle. 2021;12(6):1908-1924doi: 10.1002/jcsm.12790.
Rodrigues, A. C. Z., Messi, M. L., Wang, Z. M., Bonilla, H. J., Freeman, W. M., & Delbono, O. (2021). Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice. Journal of cachexia, sarcopenia and muscle, 12(6), 1908-1924. https://doi.org/10.1002/jcsm.12790
Rodrigues, Anna Carolina Zaia, et al. "Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice." Journal of cachexia, sarcopenia and muscle vol. 12,6 (2021): 1908-1924. doi: https://doi.org/10.1002/jcsm.12790
Rodrigues ACZ, Messi ML, Wang ZM, Bonilla HJ, Freeman WM, Delbono O. Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice. J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1908-1924. doi: 10.1002/jcsm.12790. Epub 2021 Sep 21. PMID: 34546662; PMCID: PMC8718059.
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A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study.

JMIR research protocols

Brooks AK, Miller DP, Fanning JT, Suftin EL, Reid MC, Wells BJ, Leng X, Hurley RW.
PMID: 31895042
JMIR Res Protoc. 2020 Jan 02;9(1):e14525. doi: 10.2196/14525.

BACKGROUND: Low back pain is a costly healthcare problem and the leading cause of disability among adults in the United States. Primary care providers urgently need effective ways to deliver evidence-based, nonpharmacological therapies for chronic low back pain. Guidelines...

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Brooks AK, Miller DP, Fanning JT, et al. A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study. JMIR Res Protoc. 2020;9(1):e14525doi: 10.2196/14525.
Brooks, A. K., Miller, D. P., Fanning, J. T., Suftin, E. L., Reid, M. C., Wells, B. J., Leng, X., & Hurley, R. W. (2020). A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study. JMIR research protocols, 9(1), e14525. https://doi.org/10.2196/14525
Brooks, Amber K, et al. "A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study." JMIR research protocols vol. 9,1 (2020): e14525. doi: https://doi.org/10.2196/14525
Brooks AK, Miller DP, Fanning JT, Suftin EL, Reid MC, Wells BJ, Leng X, Hurley RW. A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study. JMIR Res Protoc. 2020 Jan 02;9(1):e14525. doi: 10.2196/14525. PMID: 31895042; PMCID: PMC6966554.
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Association Between Physical Performance and Cognitive Function in Older Adults Across Multiple Studies: A Pooled Analysis Study.

Innovation in aging

Handing EP, Leng XI, Kritchevsky SB, Craft S.
PMID: 33241126
Innov Aging. 2020 Oct 12;4(6):igaa050. doi: 10.1093/geroni/igaa050. eCollection 2020.

BACKGROUND AND OBJECTIVES: While several studies have examined the association between cognitive and physical function, the consistency of these associations across functional contexts is unclear. The consistency of the association between cognitive and physical function performance was examined at...

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Handing EP, Leng XI, Kritchevsky SB, et al. Association Between Physical Performance and Cognitive Function in Older Adults Across Multiple Studies: A Pooled Analysis Study. Innov Aging. 2020;4(6):igaa050doi: 10.1093/geroni/igaa050.
Handing, E. P., Leng, X. I., Kritchevsky, S. B., & Craft, S. (2020). Association Between Physical Performance and Cognitive Function in Older Adults Across Multiple Studies: A Pooled Analysis Study. Innovation in aging, 4(6), igaa050. https://doi.org/10.1093/geroni/igaa050
Handing, Elizabeth P, et al. "Association Between Physical Performance and Cognitive Function in Older Adults Across Multiple Studies: A Pooled Analysis Study." Innovation in aging vol. 4,6 (2020): igaa050. doi: https://doi.org/10.1093/geroni/igaa050
Handing EP, Leng XI, Kritchevsky SB, Craft S. Association Between Physical Performance and Cognitive Function in Older Adults Across Multiple Studies: A Pooled Analysis Study. Innov Aging. 2020 Oct 12;4(6):igaa050. doi: 10.1093/geroni/igaa050. eCollection 2020. PMID: 33241126; PMCID: PMC7679973.
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Showing 1 to 12 of 76 entries