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Showing 1 to 12 of 137 entries
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Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes.

Oncotarget

Wang X, Malawista A, Qian F, Ramsey C, Allore HG, Montgomery RR.
PMID: 29515754
Oncotarget. 2018 Jan 03;9(11):9572-9580. doi: 10.18632/oncotarget.23851. eCollection 2018 Feb 09.

The multifactorial immune deterioration in aging--termed "inflamm-aging"--is comprised of a state of low-grade, chronic inflammation and complex dysregulation of responses to immune stimulation. The TAM family (Tyro 3, Axl, and Mer) of receptor tyrosine kinases are negative regulators of...

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Wang X, Malawista A, Qian F, et al. Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes. Oncotarget. 2018;9(11):9572-9580doi: 10.18632/oncotarget.23851.
Wang, X., Malawista, A., Qian, F., Ramsey, C., Allore, H. G., & Montgomery, R. R. (2018). Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes. Oncotarget, 9(11), 9572-9580. https://doi.org/10.18632/oncotarget.23851
Wang, Xiaomei, et al. "Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes." Oncotarget vol. 9,11 (2018): 9572-9580. doi: https://doi.org/10.18632/oncotarget.23851
Wang X, Malawista A, Qian F, Ramsey C, Allore HG, Montgomery RR. Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes. Oncotarget. 2018 Jan 03;9(11):9572-9580. doi: 10.18632/oncotarget.23851. eCollection 2018 Feb 09. PMID: 29515754; PMCID: PMC5839385.
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Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients.

International journal of statistics in medical research

Han L, Pisani MA, Araujo KL, Allore HG.
PMID: 27123153
Int J Stat Med Res. 2016;5:8-16. doi: 10.6000/1929-6029.2016.05.01.2. Epub 2016 Jan 08.

Exposure-crossover design offers a non-experimental option to control for stable baseline confounding through self-matching while examining causal effect of an exposure on an acute outcome. This study extends this approach to longitudinal data with repeated measures of exposure and...

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Han L, Pisani MA, Araujo KL, et al. Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients. Int J Stat Med Res. 2016;5:8-16doi: 10.6000/1929-6029.2016.05.01.2.
Han, L., Pisani, M. A., Araujo, K. L., & Allore, H. G. (2016). Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients. International journal of statistics in medical research, 58-16. https://doi.org/10.6000/1929-6029.2016.05.01.2
Han, Ling, et al. "Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients." International journal of statistics in medical research vol. 5 (2016): 8-16. doi: https://doi.org/10.6000/1929-6029.2016.05.01.2
Han L, Pisani MA, Araujo KL, Allore HG. Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients. Int J Stat Med Res. 2016;5:8-16. doi: 10.6000/1929-6029.2016.05.01.2. Epub 2016 Jan 08. PMID: 27123153; PMCID: PMC4844076.
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Erratum to: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions.

BMC geriatrics

Fried TR, Niehoff K, Tjia J, Redeker N, Goldstein MK.
PMID: 27312251
BMC Geriatr. 2016 Jun 16;16(1):123. doi: 10.1186/s12877-016-0300-8.

No abstract available.

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Fried TR, Niehoff K, Tjia J, et al. Erratum to: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions. BMC Geriatr. 2016;16(1):123doi: 10.1186/s12877-016-0300-8.
Fried, T. R., Niehoff, K., Tjia, J., Redeker, N., & Goldstein, M. K. (2016). Erratum to: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions. BMC geriatrics, 16(1), 123. https://doi.org/10.1186/s12877-016-0300-8
Fried, Terri R, et al. "Erratum to: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions." BMC geriatrics vol. 16,1 (2016): 123. doi: https://doi.org/10.1186/s12877-016-0300-8
Fried TR, Niehoff K, Tjia J, Redeker N, Goldstein MK. Erratum to: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions. BMC Geriatr. 2016 Jun 16;16(1):123. doi: 10.1186/s12877-016-0300-8. PMID: 27312251; PMCID: PMC4911679.
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Reply to Measuring Under- and Over-Use of Medications.

Journal of the American Geriatrics Society

Fried TR, Mecca M.
PMID: 31390042
J Am Geriatr Soc. 2019 Nov;67(11):2429. doi: 10.1111/jgs.16112. Epub 2019 Aug 07.

No abstract available.

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Fried TR, Mecca M. Reply to Measuring Under- and Over-Use of Medications. J Am Geriatr Soc. 2019;67(11):2429doi: 10.1111/jgs.16112.
Fried, T. R., & Mecca, M. (2019). Reply to Measuring Under- and Over-Use of Medications. Journal of the American Geriatrics Society, 67(11), 2429. https://doi.org/10.1111/jgs.16112
Fried, Terri R, and Mecca, Marcia. "Reply to Measuring Under- and Over-Use of Medications." Journal of the American Geriatrics Society vol. 67,11 (2019): 2429. doi: https://doi.org/10.1111/jgs.16112
Fried TR, Mecca M. Reply to Measuring Under- and Over-Use of Medications. J Am Geriatr Soc. 2019 Nov;67(11):2429. doi: 10.1111/jgs.16112. Epub 2019 Aug 07. PMID: 31390042; PMCID: PMC6861606.
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Chronic Conditions, Medically Supportive Care Partners, And Functional Disability Among Cognitively Impaired Adults.

Innovation in aging

Van Ness PH, MacNeil Vroomen J, Leo-Summers L, Vander Wyk B, Allore HG.
PMID: 31286072
Innov Aging. 2019 Jul 02;3(2):igz018. doi: 10.1093/geroni/igz018. eCollection 2019 May.

BACKGROUND AND OBJECTIVES: To assess whether medically supportive care partners modify the associations of symptomatic chronic conditions with the number of functional disabilities in a cohort of multimorbid older adults with cognitive impairment.RESEARCH DESIGN AND METHODS: The research design...

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Van Ness PH, MacNeil Vroomen J, Leo-Summers L, et al. Chronic Conditions, Medically Supportive Care Partners, And Functional Disability Among Cognitively Impaired Adults. Innov Aging. 2019;3(2):igz018doi: 10.1093/geroni/igz018.
Van Ness, P. H., MacNeil Vroomen, J., Leo-Summers, L., Vander Wyk, B., & Allore, H. G. (2019). Chronic Conditions, Medically Supportive Care Partners, And Functional Disability Among Cognitively Impaired Adults. Innovation in aging, 3(2), igz018. https://doi.org/10.1093/geroni/igz018
Van Ness, Peter H, et al. "Chronic Conditions, Medically Supportive Care Partners, And Functional Disability Among Cognitively Impaired Adults." Innovation in aging vol. 3,2 (2019): igz018. doi: https://doi.org/10.1093/geroni/igz018
Van Ness PH, MacNeil Vroomen J, Leo-Summers L, Vander Wyk B, Allore HG. Chronic Conditions, Medically Supportive Care Partners, And Functional Disability Among Cognitively Impaired Adults. Innov Aging. 2019 Jul 02;3(2):igz018. doi: 10.1093/geroni/igz018. eCollection 2019 May. PMID: 31286072; PMCID: PMC6604743.
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Burden and Management of Multidrug-Resistant Organisms in Palliative Care.

Palliative care

Datta R, Juthani-Mehta M.
PMID: 29317826
Palliat Care. 2017 Dec 19;10:1178224217749233. doi: 10.1177/1178224217749233. eCollection 2017.

Palliative care includes comprehensive strategies to optimize quality of life for patients and families confronting terminal illness. Infections are a common complication in terminal illness, and infections due to multidrug-resistant organisms (MDROs) are particularly challenging to manage in palliative...

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Datta R, Juthani-Mehta M. Burden and Management of Multidrug-Resistant Organisms in Palliative Care. Palliat Care. 2017;10:1178224217749233doi: 10.1177/1178224217749233.
Datta, R., & Juthani-Mehta, M. (2017). Burden and Management of Multidrug-Resistant Organisms in Palliative Care. Palliative care, 101178224217749233. https://doi.org/10.1177/1178224217749233
Datta, Rupak, and Juthani-Mehta, Manisha. "Burden and Management of Multidrug-Resistant Organisms in Palliative Care." Palliative care vol. 10 (2017): 1178224217749233. doi: https://doi.org/10.1177/1178224217749233
Datta R, Juthani-Mehta M. Burden and Management of Multidrug-Resistant Organisms in Palliative Care. Palliat Care. 2017 Dec 19;10:1178224217749233. doi: 10.1177/1178224217749233. eCollection 2017. PMID: 29317826; PMCID: PMC5753884.
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Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis.

Scientific reports

Liu Z, Burgess S, Wang Z, Deng W, Chu X, Cai J, Zhu Y, Shi J, Xie X, Wang Y, Jin L, Wang X.
PMID: 28134330
Sci Rep. 2017 Jan 30;7:41579. doi: 10.1038/srep41579.

Observational studies suggest associations of triglyceride levels with longevity and frailty. This study aimed to test whether the associations are causal. We used data from the Rugao Longevity and Ageing Study, a population-based cohort study performed in Rugao, China....

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Liu Z, Burgess S, Wang Z, et al. Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis. Sci Rep. 2017;7:41579doi: 10.1038/srep41579.
Liu, Z., Burgess, S., Wang, Z., Deng, W., Chu, X., Cai, J., Zhu, Y., Shi, J., Xie, X., Wang, Y., Jin, L., & Wang, X. (2017). Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis. Scientific reports, 741579. https://doi.org/10.1038/srep41579
Liu, Zuyun, et al. "Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis." Scientific reports vol. 7 (2017): 41579. doi: https://doi.org/10.1038/srep41579
Liu Z, Burgess S, Wang Z, Deng W, Chu X, Cai J, Zhu Y, Shi J, Xie X, Wang Y, Jin L, Wang X. Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis. Sci Rep. 2017 Jan 30;7:41579. doi: 10.1038/srep41579. PMID: 28134330; PMCID: PMC5278549.
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Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults.

Frontiers in aging neuroscience

Wanigatunga AA, Manini TM, Cook DR, Katula J, Fielding RA, Kramer AF, Verghese J, Rapp SR, Sink KM, King AC, Buford TW, Anton S, Nadkarni N, Jennings JM, Reid K, Espeland MA, Gill TM, Pahor M, Nocera JR.
PMID: 30498440
Front Aging Neurosci. 2018 Nov 15;10:341. doi: 10.3389/fnagi.2018.00341. eCollection 2018.

Over the last few decades, considerable evidence shows that greater levels of aerobic exercise and cardiovascular fitness benefit cognitive performance. However, the degree to which free-living activity in community settings is related to cognitive performance remains unclear, particularly in...

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Wanigatunga AA, Manini TM, Cook DR, et al. Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci. 2018;10:341doi: 10.3389/fnagi.2018.00341.
Wanigatunga, A. A., Manini, T. M., Cook, D. R., Katula, J., Fielding, R. A., Kramer, A. F., Verghese, J., Rapp, S. R., Sink, K. M., King, A. C., Buford, T. W., Anton, S., Nadkarni, N., Jennings, J. M., Reid, K., Espeland, M. A., Gill, T. M., Pahor, M., & Nocera, J. R. (2018). Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Frontiers in aging neuroscience, 10341. https://doi.org/10.3389/fnagi.2018.00341
Wanigatunga, Amal A, et al. "Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults." Frontiers in aging neuroscience vol. 10 (2018): 341. doi: https://doi.org/10.3389/fnagi.2018.00341
Wanigatunga AA, Manini TM, Cook DR, Katula J, Fielding RA, Kramer AF, Verghese J, Rapp SR, Sink KM, King AC, Buford TW, Anton S, Nadkarni N, Jennings JM, Reid K, Espeland MA, Gill TM, Pahor M, Nocera JR. Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci. 2018 Nov 15;10:341. doi: 10.3389/fnagi.2018.00341. eCollection 2018. PMID: 30498440; PMCID: PMC6249499.
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An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU.

International journal of statistics in medical research

Murphy TE, Van Ness PH, Araujo KL, Pisani MA.
PMID: 26798411
Int J Stat Med Res. 2016;5(1):41-47. doi: 10.6000/1929-6029.2016.05.01.4. Epub 2016 Jan 08.

Longitudinal research on older persons in the medical intensive care unit (MICU) is often complicated by the time-dependent confounding of concurrently administered interventions such as medications and intubation. Such temporal confounding can bias the respective longitudinal associations between concurrently...

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Murphy TE, Van Ness PH, Araujo KL, et al. An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU. Int J Stat Med Res. 2016;5(1):41-47doi: 10.6000/1929-6029.2016.05.01.4.
Murphy, T. E., Van Ness, P. H., Araujo, K. L., & Pisani, M. A. (2016). An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU. International journal of statistics in medical research, 5(1), 41-47. https://doi.org/10.6000/1929-6029.2016.05.01.4
Murphy, T E, et al. "An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU." International journal of statistics in medical research vol. 5,1 (2016): 41-47. doi: https://doi.org/10.6000/1929-6029.2016.05.01.4
Murphy TE, Van Ness PH, Araujo KL, Pisani MA. An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU. Int J Stat Med Res. 2016;5(1):41-47. doi: 10.6000/1929-6029.2016.05.01.4. Epub 2016 Jan 08. PMID: 26798411; PMCID: PMC4718607.
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Serious adverse events of older adults in nursing home and community intervention trials.

Contemporary clinical trials communications

Datta R, Trentalange M, Van Ness PH, McGloin JM, Guralnik JM, Miller ME, Walkup MP, Nadkarni N, Pahor M, Gill TM, Quagliarello V, Juthani-Mehta M.
PMID: 29696228
Contemp Clin Trials Commun. 2017 Dec 21;9:77-80. doi: 10.1016/j.conctc.2017.12.004. eCollection 2018 Mar.

BACKGROUND/AIMS: Clinical trials of older adults are increasingly common, but risks of serious adverse events (SAE) may vary. We describe the incidence of SAE in two randomized trials, one community-based and one nursing home-based.METHODS: We performed a secondary data...

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Datta R, Trentalange M, Van Ness PH, et al. Serious adverse events of older adults in nursing home and community intervention trials. Contemp Clin Trials Commun. 2017;9:77-80doi: 10.1016/j.conctc.2017.12.004.
Datta, R., Trentalange, M., Van Ness, P. H., McGloin, J. M., Guralnik, J. M., Miller, M. E., Walkup, M. P., Nadkarni, N., Pahor, M., Gill, T. M., Quagliarello, V., Juthani-Mehta, M. (2018). Serious adverse events of older adults in nursing home and community intervention trials. Contemporary clinical trials communications, 977-80. https://doi.org/10.1016/j.conctc.2017.12.004
Datta, Rupak, et al. "Serious adverse events of older adults in nursing home and community intervention trials." Contemporary clinical trials communications vol. 9 (2018): 77-80. doi: https://doi.org/10.1016/j.conctc.2017.12.004
Datta R, Trentalange M, Van Ness PH, McGloin JM, Guralnik JM, Miller ME, Walkup MP, Nadkarni N, Pahor M, Gill TM, Quagliarello V, Juthani-Mehta M. Serious adverse events of older adults in nursing home and community intervention trials. Contemp Clin Trials Commun. 2017 Dec 21;9:77-80. doi: 10.1016/j.conctc.2017.12.004. eCollection 2018 Mar. PMID: 29696228; PMCID: PMC5898490.
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Treatment of Hypertension in Complex Older Adults: How Many Medications Are Needed?.

Gerontology & geriatric medicine

Ouellet GM, McAvay G, Murphy TE, Tinetti ME.
PMID: 31245434
Gerontol Geriatr Med. 2019 Jun 17;5:2333721419856436. doi: 10.1177/2333721419856436. eCollection 2019.

No abstract available.

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Ouellet GM, McAvay G, Murphy TE, et al. Treatment of Hypertension in Complex Older Adults: How Many Medications Are Needed?. Gerontol Geriatr Med. 2019;5:2333721419856436doi: 10.1177/2333721419856436.
Ouellet, G. M., McAvay, G., Murphy, T. E., & Tinetti, M. E. (2019). Treatment of Hypertension in Complex Older Adults: How Many Medications Are Needed?. Gerontology & geriatric medicine, 52333721419856436. https://doi.org/10.1177/2333721419856436
Ouellet, Gregory M, et al. "Treatment of Hypertension in Complex Older Adults: How Many Medications Are Needed?." Gerontology & geriatric medicine vol. 5 (2019): 2333721419856436. doi: https://doi.org/10.1177/2333721419856436
Ouellet GM, McAvay G, Murphy TE, Tinetti ME. Treatment of Hypertension in Complex Older Adults: How Many Medications Are Needed?. Gerontol Geriatr Med. 2019 Jun 17;5:2333721419856436. doi: 10.1177/2333721419856436. eCollection 2019. PMID: 31245434; PMCID: PMC6580710.
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Medication appropriateness criteria for older adults: a narrative review of criteria and supporting studies.

Therapeutic advances in drug safety

Niehoff KM, Mecca MC, Fried TR.
PMID: 30719279
Ther Adv Drug Saf. 2019 Jan 18;10:2042098618815431. doi: 10.1177/2042098618815431. eCollection 2019.

Polypharmacy is common among older adults and is associated with adverse outcomes. Polypharmacy increases the likelihood of receiving a potentially inappropriate medication (PIM). PIMs have traditionally been defined as medications that have either no benefit (e.g. therapeutic duplication) or...

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Niehoff KM, Mecca MC, Fried TR. Medication appropriateness criteria for older adults: a narrative review of criteria and supporting studies. Ther Adv Drug Saf. 2019;10:2042098618815431doi: 10.1177/2042098618815431.
Niehoff, K. M., Mecca, M. C., & Fried, T. R. (2019). Medication appropriateness criteria for older adults: a narrative review of criteria and supporting studies. Therapeutic advances in drug safety, 102042098618815431. https://doi.org/10.1177/2042098618815431
Niehoff, Kristina M, et al. "Medication appropriateness criteria for older adults: a narrative review of criteria and supporting studies." Therapeutic advances in drug safety vol. 10 (2019): 2042098618815431. doi: https://doi.org/10.1177/2042098618815431
Niehoff KM, Mecca MC, Fried TR. Medication appropriateness criteria for older adults: a narrative review of criteria and supporting studies. Ther Adv Drug Saf. 2019 Jan 18;10:2042098618815431. doi: 10.1177/2042098618815431. eCollection 2019. PMID: 30719279; PMCID: PMC6348576.
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Showing 1 to 12 of 137 entries