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Showing 1 to 12 of 220 entries
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Autophagy in Ischemic Livers: A Critical Role of Sirtuin 1/Mitofusin 2 Axis in Autophagy Induction.

Toxicological research

Chun SK, Go K, Yang MJ, Zendejas I, Behrns KE, Kim JS.
PMID: 26977257
Toxicol Res. 2016 Jan;32(1):35-46. doi: 10.5487/TR.2016.32.1.035. Epub 2016 Jan 31.

No-flow ischemia occurs during cardiac arrest, hemorrhagic shock, liver resection and transplantation. Recovery of blood flow and normal physiological pH, however, irreversibly injures the liver and other tissues. Although the liver has the powerful machinery for mitochondrial quality control,...

Transcription Profile of Aging and Cognition-Related Genes in the Medial Prefrontal Cortex.

Frontiers in aging neuroscience

Ianov L, Rani A, Beas BS, Kumar A, Foster TC.
PMID: 27242522
Front Aging Neurosci. 2016 May 17;8:113. doi: 10.3389/fnagi.2016.00113. eCollection 2016.

Cognitive function depends on transcription; however, there is little information linking altered gene expression to impaired prefrontal cortex function during aging. Young and aged F344 rats were characterized on attentional set shift and spatial memory tasks. Transcriptional differences associated...

Reply from Elizabeth Schroder, Brian Hodge, Lance Riley, Xiping Zhang and Karyn Esser.

The Journal of physiology

Schroder E, Hodge B, Riley L, Zhang X, Esser K.
PMID: 27246552
J Physiol. 2016 Jun 01;594(11):3163-4. doi: 10.1113/JP272165.

No abstract available.

Mobile Device Accuracy for Step Counting Across Age Groups.

JMIR mHealth and uHealth

Modave F, Guo Y, Bian J, Gurka MJ, Parish A, Smith MD, Lee AM, Buford TW.
PMID: 28659255
JMIR Mhealth Uhealth. 2017 Jun 28;5(6):e88. doi: 10.2196/mhealth.7870.

BACKGROUND: Only one in five American meets the physical activity recommendations of the Department of Health and Human Services. The proliferation of wearable devices and smartphones for physical activity tracking has led to an increasing number of interventions designed...

WHAT WE HAVE LEARNED FROM EXERCISE AND LIFESTYLE TRIALS TO ALLEVIATE MOBILITY IMPAIRMENT IN OLDER ADULTS.

The Journal of frailty & aging

Manini TM, Clark BC.
PMID: 26568947
J Frailty Aging. 2013;2(1):57-9.

Enhancement of cardiovascular and muscular fitness through exercise and lifestyle interventions is critical to in alleviating mobility impairment in older adults. In this review article, we discuss the current knowledge-base surrounding mobility improvements in seniors following behavioral interventions that...

Mitophagy: therapeutic potentials for liver disease and beyond.

Toxicological research

Lee S, Kim JS.
PMID: 25584143
Toxicol Res. 2014 Dec;30(4):243-50. doi: 10.5487/TR.2014.30.4.243.

Mitochondrial integrity is critical for maintaining proper cellular functions. A key aspect of regulating mitochondrial homeostasis is removing damaged mitochondria through autophagy, a process called mitophagy. Autophagy dysfunction in various disease states can inactivate mitophagy and cause cell death,...

The authors reply.

Critical care medicine

Moldawer LL, Efron PA, Brakenridge S, Moore FA.
PMID: 28622238
Crit Care Med. 2017 Jul;45(7):e740-e741. doi: 10.1097/CCM.0000000000002469.

No abstract available.

Variation in the Oxytocin Receptor Gene Is Associated with Face Recognition and its Neural Correlates.

Frontiers in behavioral neuroscience

Westberg L, Henningsson S, Zettergren A, Svärd J, Hovey D, Lin T, Ebner NC, Fischer H.
PMID: 27713694
Front Behav Neurosci. 2016 Sep 22;10:178. doi: 10.3389/fnbeh.2016.00178. eCollection 2016.

The ability to recognize faces is crucial for daily social interactions. Recent studies suggest that intranasal oxytocin administration improves social recognition in humans. Oxytocin signaling in the amygdala plays an essential role for social recognition in mice, and oxytocin...

Erratum to: Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study.

Journal of translational medicine

White SH, McDermott MM, Sufit RL, Kosmac K, Bugg AW, Gonzalez-Freire M, Ferrucci L, Tian L, Zhao L, Gao Y, Kibbe MR, Criqui MH, Leeuwenburgh C, Peterson CA.
PMID: 28241774
J Transl Med. 2017 Feb 23;15(1):45. doi: 10.1186/s12967-017-1127-6.

No abstract available.

Examining Healthcare Utilization Patterns of Elderly Middle-Aged Adults in the United States.

Proceedings of the ... International Florida AI Research Society Conference. Florida AI Research Symposium

Zayas CE, He Z, Yuan J, Maldonado-Molina M, Hogan W, Modave F, Guo Y, Bian J.
PMID: 27430035
Proc Int Fla AI Res Soc Conf. 2016 May;2016:361-366.

Elderly patients, aged 65 or older, make up 13.5% of the U.S. population, but represent 45.2% of the top 10% of healthcare utilizers, in terms of expenditures. Middle-aged Americans, aged 45 to 64 make up another 37.0% of that...

Using physical activity to gain the most public health bang for the buck.

JAMA internal medicine

Manini TM.
PMID: 25844886
JAMA Intern Med. 2015 Jun;175(6):968-9. doi: 10.1001/jamainternmed.2015.0544.

No abstract available.

Innovative Medicines Initiative: The SPRINTT Project.

The Journal of frailty & aging

Marzetti E, Calvani R, Landi F, Hoogendijk EO, Fougère B, Vellas B, Pahor M, Bernabei R, Cesari M.
PMID: 26693163
J Frailty Aging. 2015 Dec 01;4(4):207-208.

No abstract available.

Showing 1 to 12 of 220 entries