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Front Behav Neurosci. 2016 Sep 22;10:178. doi: 10.3389/fnbeh.2016.00178. eCollection 2016.

Variation in the Oxytocin Receptor Gene Is Associated with Face Recognition and its Neural Correlates.

Frontiers in behavioral neuroscience

Lars Westberg, Susanne Henningsson, Anna Zettergren, Joakim Svärd, Daniel Hovey, Tian Lin, Natalie C Ebner, Håkan Fischer

Affiliations

  1. Department of Pharmacology, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg Gothenburg, Sweden.
  2. Department of Pharmacology, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of GothenburgGothenburg, Sweden; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of GothenburgGothenburg, Sweden.
  3. Aging Research Center, Karolinska Institutet Stockholm, Sweden.
  4. Department of Psychology, University of Florida Gainesville, FL, USA.
  5. Department of Psychology, University of FloridaGainesville, FL, USA; Department of Aging and Geriatric Research, University of FloridaGainesville, FL, USA.
  6. Aging Research Center, Karolinska InstitutetStockholm, Sweden; Department of Psychology, Stockholm UniversityStockholm, Sweden.

PMID: 27713694 PMCID: PMC5031602 DOI: 10.3389/fnbeh.2016.00178

Abstract

The ability to recognize faces is crucial for daily social interactions. Recent studies suggest that intranasal oxytocin administration improves social recognition in humans. Oxytocin signaling in the amygdala plays an essential role for social recognition in mice, and oxytocin administration has been shown to influence amygdala activity in humans. It is therefore possible that the effects of oxytocin on human social recognition depend on mechanisms that take place in the amygdala-a central region for memory processing also in humans. Variation in the gene encoding the oxytocin receptor (

Keywords: OXTR; face recognition; oxytocin; polymorphism; social cognition

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