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Showing 1 to 12 of 297 entries
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Adult Acute Myeloid Leukemia Long-term Survivors.

Journal of leukemia (Los Angeles, Calif.)

Cheng MJ, Hourigan CS, Smith TJ.
PMID: 25243197
J Leuk (Los Angel). 2014 Apr 10;2(2). doi: 10.4172/2329-6917.1000135.

The number of leukemia patients and survivors is growing. This review summarizes what is known regarding the health related quality of life (HRQOL) and medical complications associated with acute myeloid leukemia (AML) disease and treatment and highlights understudied aspects...

Oncotarget

Pankov D, Sjöström L, Kalidindi T, Lee SG, Sjöström K, Gardner R, McDevitt MR, O'Reilly R, Thorek DLJ, Larson SM, Veach D, Ulmert D.
PMID: 29029482
Oncotarget. 2017 Jul 26;8(39):65917-65931. doi: 10.18632/oncotarget.19579. eCollection 2017 Sep 12.

Preferentially Expressed Antigen in Melanoma (PRAME) is a cancer/testis antigen that is overexpressed in a broad range of malignancies, while absent in most healthy human tissues, making it an attractive diagnostic cancer biomarker and therapeutic target. Although commonly viewed...

A Patient with HIV Treated with Ipilimumab and Stereotactic Radiosurgery for Melanoma Metastases to the Brain.

Case reports in oncological medicine

Ruzevick J, Nicholas S, Redmond K, Kleinberg L, Lipson EJ, Lim M.
PMID: 24383025
Case Rep Oncol Med. 2013;2013:946392. doi: 10.1155/2013/946392. Epub 2013 Dec 08.

Cancers, such as melanoma, that are associated with immune deficiencies are a major cause of morbidity and mortality in HIV-infected patients. Once patients develop melanoma metastases to the brain, treatment is often limited to palliative surgery and/or radiation. Ipilimumab,...

Molecular heterogeneity of localized prostate cancer: more different than alike.

Translational cancer research

Tosoian JJ, Antonarakis ES.
PMID: 28529909
Transl Cancer Res. 2017 Feb;6:S47-S50. doi: 10.21037/tcr.2017.02.17.

No abstract available.

Practice gaps and barriers to optimal care of hematologic malignancies in the United States.

The Journal of community and supportive oncology

Murray S, Obholz KL, Bowser AD, Mortimer J, Lazure P, Peterson E, Armitage JO, Smith BD.
PMID: 25811037
J Community Support Oncol. 2014 Sep;12(9):329-338. doi: 10.12788/jcso.0073.

BACKGROUND: Treating patients with hematologic malignancies can be challenging for physicians because of the rapidly evolving standards of care and relatively low incidence of these diseases.OBJECTIVE: To identify clinical challenges among hematologists and medical oncologists regarding the provision of...

Beefing up prostate cancer therapy with performance-enhancing (anti-) steroids.

Cancer cell

Nelson WG, Haffner MC, Yegnasubramanian S.
PMID: 21741594
Cancer Cell. 2011 Jul 12;20(1):7-9. doi: 10.1016/j.ccr.2011.06.019.

In the May 26th issue of the New England Journal of Medicine, de Bono et al. report that the inhibition of androgen synthesis by abiraterone acetate prolonged the survival of men with prostate cancer previously treated by androgen suppression.

Implications of systemic dysfunction for the etiology of malignancy.

Gene regulation and systems biology

Knox SS, Ochs MF.
PMID: 23440603
Gene Regul Syst Bio. 2013;7:11-22. doi: 10.4137/GRSB.S10943. Epub 2013 Feb 06.

The current approach to treatment in oncology is to replace the generally cytotoxic chemotherapies with pharmaceutical treatment which inactivates specific molecular targets associated with cancer development and progression. The goal is to limit cellular damage to pathways perceived to...

Infection of Xenotransplanted Human Cell Lines by Murine Retroviruses: A Lesson Brought Back to Light by XMRV.

Frontiers in oncology

Hempel HA, Burns KH, De Marzo AM, Sfanos KS.
PMID: 23785669
Front Oncol. 2013 Jun 17;3:156. doi: 10.3389/fonc.2013.00156. eCollection 2013.

Infection of xenotransplanted human cells by xenotropic retroviruses is a known phenomenon in the scientific literature, with examples cited since the early 1970s. However, arguably, until recently, the importance of this phenomenon had not been largely recognized. The emergence...

Infections and inflammation in prostate cancer.

American journal of clinical and experimental urology

Sfanos KS, Isaacs WB, De Marzo AM.
PMID: 25110720
Am J Clin Exp Urol. 2013 Dec 25;1(1):3-11.

The frequent observation of both acute and chronic inflammation of unknown stimulus in the adult prostate has motivated a large body of research aimed at identifying potential infectious agents that may elicit prostatic inflammation. The overarching hypothesis is that...

Oncotarget

Gustin JP, Miller J, Farag M, Rosen DM, Thomas M, Scharpf RB, Lauring J.
PMID: 29262572
Oncotarget. 2017 Oct 20;8(61):103415-103427. doi: 10.18632/oncotarget.21910. eCollection 2017 Nov 28.

The

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3.

Oncotarget

Nagai K, Hou L, Li L, Nguyen B, Seale T, Shirley C, Ma H, Levis M, Ghiaur G, Duffield A, Small D.
PMID: 30250637
Oncotarget. 2018 Aug 31;9(68):32885-32899. doi: 10.18632/oncotarget.25972. eCollection 2018 Aug 31.

Acute myeloid leukemia (AML) patients with FLT3/ITD mutations have a poor prognosis. Monotherapy with selective FLT3 tyrosine kinase inhibitors (TKIs) have shown transient and limited efficacy due to the development of resistance. Arsenic trioxide (ATO, As

AR-V7 and treatment selection in advanced prostate cancer: are we there yet?.

Precision cancer medicine

Bastos DA, Antonarakis ES.
PMID: 30370427
Precis Cancer Med. 2018 Sep;1. doi: 10.21037/pcm.2018.09.01. Epub 2018 Sep 18.

No abstract available.

Showing 1 to 12 of 297 entries