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Showing 1 to 12 of 162 entries
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Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib.

Clinical and translational medicine

Shivapurkar N, Vietsch EE, Carney E, Isaacs C, Wellstein A.
PMID: 28980224
Clin Transl Med. 2017 Oct 04;6(1):37. doi: 10.1186/s40169-017-0169-y.

BACKGROUND: Serial analysis of biomarkers in the circulation of patients undergoing treatment ("liquid biopsies") can provide new insights into drug effects. In particular the analysis of cell-free, circulating nucleic acids such as microRNAs (miRs) can reveal altered expression patterns...

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Shivapurkar N, Vietsch EE, Carney E, et al. Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib. Clin Transl Med. 2017;6(1):37doi: 10.1186/s40169-017-0169-y.
Shivapurkar, N., Vietsch, E. E., Carney, E., Isaacs, C., & Wellstein, A. (2017). Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib. Clinical and translational medicine, 6(1), 37. https://doi.org/10.1186/s40169-017-0169-y
Shivapurkar, Narayan, et al. "Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib." Clinical and translational medicine vol. 6,1 (2017): 37. doi: https://doi.org/10.1186/s40169-017-0169-y
Shivapurkar N, Vietsch EE, Carney E, Isaacs C, Wellstein A. Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib. Clin Transl Med. 2017 Oct 04;6(1):37. doi: 10.1186/s40169-017-0169-y. PMID: 28980224; PMCID: PMC5628092.
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Video intervention increases participation of black breast cancer patients in therapeutic trials.

NPJ breast cancer

Robinson BN, Newman AF, Tefera E, Herbolsheimer P, Nunes R, Gallagher C, Randolph-Jackson P, Omogbehin A, Dilawari A, Pohlmann PR, Mohebtash M, Lee Y, Ottaviano Y, Mohapatra A, Lynce F, Brown R, Mete M, Swain SM.
PMID: 28944289
NPJ Breast Cancer. 2017 Sep 18;3:36. doi: 10.1038/s41523-017-0039-1. eCollection 2017.

There is a striking racial and ethnic disparity in incidence and mortality of cancer yet minorities remain markedly underrepresented in clinical trials. This pilot study set out to determine the impact of a 15-min culturally tailored educational video on...

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Robinson BN, Newman AF, Tefera E, et al. Video intervention increases participation of black breast cancer patients in therapeutic trials. NPJ Breast Cancer. 2017;3:36doi: 10.1038/s41523-017-0039-1.
Robinson, B. N., Newman, A. F., Tefera, E., Herbolsheimer, P., Nunes, R., Gallagher, C., Randolph-Jackson, P., Omogbehin, A., Dilawari, A., Pohlmann, P. R., Mohebtash, M., Lee, Y., Ottaviano, Y., Mohapatra, A., Lynce, F., Brown, R., Mete, M., & Swain, S. M. (2017). Video intervention increases participation of black breast cancer patients in therapeutic trials. NPJ breast cancer, 336. https://doi.org/10.1038/s41523-017-0039-1
Robinson, Brandi N, et al. "Video intervention increases participation of black breast cancer patients in therapeutic trials." NPJ breast cancer vol. 3 (2017): 36. doi: https://doi.org/10.1038/s41523-017-0039-1
Robinson BN, Newman AF, Tefera E, Herbolsheimer P, Nunes R, Gallagher C, Randolph-Jackson P, Omogbehin A, Dilawari A, Pohlmann PR, Mohebtash M, Lee Y, Ottaviano Y, Mohapatra A, Lynce F, Brown R, Mete M, Swain SM. Video intervention increases participation of black breast cancer patients in therapeutic trials. NPJ Breast Cancer. 2017 Sep 18;3:36. doi: 10.1038/s41523-017-0039-1. eCollection 2017. PMID: 28944289; PMCID: PMC5603544.
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Metabolomic biomarkers of pancreatic cancer: a meta-analysis study.

Oncotarget

Mehta KY, Wu HJ, Menon SS, Fallah Y, Zhong X, Rizk N, Unger K, Mapstone M, Fiandaca MS, Federoff HJ, Cheema AK.
PMID: 28978166
Oncotarget. 2017 Aug 18;8(40):68899-68915. doi: 10.18632/oncotarget.20324. eCollection 2017 Sep 15.

Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is no blood test for early detection and diagnosis of this disease. Several research groups have reported on metabolomics based clinical investigations to identify biomarkers of...

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Mehta KY, Wu HJ, Menon SS, et al. Metabolomic biomarkers of pancreatic cancer: a meta-analysis study. Oncotarget. 2017;8(40):68899-68915doi: 10.18632/oncotarget.20324.
Mehta, K. Y., Wu, H. J., Menon, S. S., Fallah, Y., Zhong, X., Rizk, N., Unger, K., Mapstone, M., Fiandaca, M. S., Federoff, H. J., & Cheema, A. K. (2017). Metabolomic biomarkers of pancreatic cancer: a meta-analysis study. Oncotarget, 8(40), 68899-68915. https://doi.org/10.18632/oncotarget.20324
Mehta, Khyati Y, et al. "Metabolomic biomarkers of pancreatic cancer: a meta-analysis study." Oncotarget vol. 8,40 (2017): 68899-68915. doi: https://doi.org/10.18632/oncotarget.20324
Mehta KY, Wu HJ, Menon SS, Fallah Y, Zhong X, Rizk N, Unger K, Mapstone M, Fiandaca MS, Federoff HJ, Cheema AK. Metabolomic biomarkers of pancreatic cancer: a meta-analysis study. Oncotarget. 2017 Aug 18;8(40):68899-68915. doi: 10.18632/oncotarget.20324. eCollection 2017 Sep 15. PMID: 28978166; PMCID: PMC5620306.
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Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat.

Metabolomics : Official journal of the Metabolomic Society

Mak TD, Tyburski JB, Krausz KW, Kalinich JF, Gonzalez FJ, Fornace AJ.
PMID: 26557048
Metabolomics. 2015 Oct 01;11(5):1082-1094. doi: 10.1007/s11306-014-0765-4. Epub 2014 Dec 20.

The potential for exposures to ionizing radiation has increased in recent years. Although advances have been made, understanding the global metabolic response as a function of both dose and exposure time is challenging considering the complexity of the responses....

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Mak TD, Tyburski JB, Krausz KW, et al. Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat. Metabolomics. 2014;11(5):1082-1094doi: 10.1007/s11306-014-0765-4.
Mak, T. D., Tyburski, J. B., Krausz, K. W., Kalinich, J. F., Gonzalez, F. J., & Fornace, A. J. (2015). Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat. Metabolomics : Official journal of the Metabolomic Society, 11(5), 1082-1094. https://doi.org/10.1007/s11306-014-0765-4
Mak, Tytus D, et al. "Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat." Metabolomics : Official journal of the Metabolomic Society vol. 11,5 (2015): 1082-1094. doi: https://doi.org/10.1007/s11306-014-0765-4
Mak TD, Tyburski JB, Krausz KW, Kalinich JF, Gonzalez FJ, Fornace AJ. Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat. Metabolomics. 2015 Oct 01;11(5):1082-1094. doi: 10.1007/s11306-014-0765-4. Epub 2014 Dec 20. PMID: 26557048; PMCID: PMC4635442.
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Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance).

Cancer

Mandelblatt JS, Clapp JD, Luta G, Faul LA, Tallarico MD, McClendon TD, Whitley JA, Cai L, Ahles TA, Stern RA, Jacobsen PB, Small BJ, Pitcher BN, Dura-Fernandis E, Muss HB, Hurria A, Cohen HJ, Isaacs C.
PMID: 27447359
Cancer. 2016 Nov 15;122(22):3555-3563. doi: 10.1002/cncr.30208. Epub 2016 Jul 22.

BACKGROUND: The number of survivors of breast cancer aged ≥65 years ("older") is growing, but to the authors' knowledge, little is known regarding the cognitive outcomes of these individuals.METHODS: A cohort of cognitively intact older survivors with nonmetastatic, invasive...

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Mandelblatt JS, Clapp JD, Luta G, et al. Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance). Cancer. 2016;122(22):3555-3563doi: 10.1002/cncr.30208.
Mandelblatt, J. S., Clapp, J. D., Luta, G., Faul, L. A., Tallarico, M. D., McClendon, T. D., Whitley, J. A., Cai, L., Ahles, T. A., Stern, R. A., Jacobsen, P. B., Small, B. J., Pitcher, B. N., Dura-Fernandis, E., Muss, H. B., Hurria, A., Cohen, H. J., & Isaacs, C. (2016). Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance). Cancer, 122(22), 3555-3563. https://doi.org/10.1002/cncr.30208
Mandelblatt, Jeanne S, et al. "Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance)." Cancer vol. 122,22 (2016): 3555-3563. doi: https://doi.org/10.1002/cncr.30208
Mandelblatt JS, Clapp JD, Luta G, Faul LA, Tallarico MD, McClendon TD, Whitley JA, Cai L, Ahles TA, Stern RA, Jacobsen PB, Small BJ, Pitcher BN, Dura-Fernandis E, Muss HB, Hurria A, Cohen HJ, Isaacs C. Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance). Cancer. 2016 Nov 15;122(22):3555-3563. doi: 10.1002/cncr.30208. Epub 2016 Jul 22. PMID: 27447359; PMCID: PMC5113662.
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Vitamin E Nicotinate.

Antioxidants (Basel, Switzerland)

Duncan KR, Suzuki YJ.
PMID: 28335380
Antioxidants (Basel). 2017 Mar 13;6(1). doi: 10.3390/antiox6010020.

Vitamin E refers to a family of compounds that function as lipid-soluble antioxidants capable of preventing lipid peroxidation. Naturally occurring forms of vitamin E include tocopherols and tocotrienols. Vitamin E in dietary supplements and fortified foods is often an...

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Duncan KR, Suzuki YJ. Vitamin E Nicotinate. Antioxidants (Basel). 2017;6(1)doi: 10.3390/antiox6010020.
Duncan, K. R., & Suzuki, Y. J. (2017). Vitamin E Nicotinate. Antioxidants (Basel, Switzerland), 6(1), . https://doi.org/10.3390/antiox6010020
Duncan, Kimbell R, and Suzuki, Yuichiro J. "Vitamin E Nicotinate." Antioxidants (Basel, Switzerland) vol. 6,1 (2017). doi: https://doi.org/10.3390/antiox6010020
Duncan KR, Suzuki YJ. Vitamin E Nicotinate. Antioxidants (Basel). 2017 Mar 13;6(1). doi: 10.3390/antiox6010020. PMID: 28335380; PMCID: PMC5384183.
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Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway.

Journal of Cancer

Datta K, Suman S, Kumar S, Fornace AJ.
PMID: 26819641
J Cancer. 2016 Jan 01;7(2):174-83. doi: 10.7150/jca.13387. eCollection 2016.

Adult colorectal epithelium undergoes continuous renewal and maintains homeostatic balance through regulated cellular proliferation, differentiation, and migration. The canonical Wnt signaling pathway involving the transcriptional co-activator β-catenin is important for colorectal development and normal epithelial maintenance, and deregulated Wnt/β-catenin...

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Datta K, Suman S, Kumar S, et al. Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway. J Cancer. 2016;7(2):174-83doi: 10.7150/jca.13387.
Datta, K., Suman, S., Kumar, S., & Fornace, A. J. (2016). Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway. Journal of Cancer, 7(2), 174-83. https://doi.org/10.7150/jca.13387
Datta, Kamal, et al. "Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway." Journal of Cancer vol. 7,2 (2016): 174-83. doi: https://doi.org/10.7150/jca.13387
Datta K, Suman S, Kumar S, Fornace AJ. Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway. J Cancer. 2016 Jan 01;7(2):174-83. doi: 10.7150/jca.13387. eCollection 2016. PMID: 26819641; PMCID: PMC4716850.
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A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation.

Metabolomics : Official journal of the Metabolomic Society

Pannkuk EL, Laiakis EC, Mak TD, Astarita G, Authier S, Wong K, Fornace AJ.
PMID: 28220056
Metabolomics. 2016 May;12(5). doi: 10.1007/s11306-016-1010-0. Epub 2016 Mar 15.

INTRODUCTION: Due to dangers associated with potential accidents from nuclear energy and terrorist threats, there is a need for high-throughput biodosimetry to rapidly assess individual doses of radiation exposure. Lipidomics and metabolomics are becoming common tools for determining global...

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Pannkuk EL, Laiakis EC, Mak TD, et al. A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation. Metabolomics. 2016;12(5)doi: 10.1007/s11306-016-1010-0.
Pannkuk, E. L., Laiakis, E. C., Mak, T. D., Astarita, G., Authier, S., Wong, K., & Fornace, A. J. (2016). A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation. Metabolomics : Official journal of the Metabolomic Society, 12(5), . https://doi.org/10.1007/s11306-016-1010-0
Pannkuk, Evan L, et al. "A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation." Metabolomics : Official journal of the Metabolomic Society vol. 12,5 (2016). doi: https://doi.org/10.1007/s11306-016-1010-0
Pannkuk EL, Laiakis EC, Mak TD, Astarita G, Authier S, Wong K, Fornace AJ. A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation. Metabolomics. 2016 May;12(5). doi: 10.1007/s11306-016-1010-0. Epub 2016 Mar 15. PMID: 28220056; PMCID: PMC5314995.
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Disparities in knowledge and willingness to donate research biospecimens: a mixed-methods study in an underserved urban community.

Journal of community genetics

Dash C, Wallington SF, Muthra S, Dodson E, Mandelblatt J, Adams-Campbell LL.
PMID: 24771039
J Community Genet. 2014 Oct;5(4):329-36. doi: 10.1007/s12687-014-0187-z. Epub 2014 Apr 26.

Although research involving biospecimens is essential in advancing cancer research, minorities, especially African-Americans, are underrepresented in such research. We conducted a mixed-method (qualitative focus groups among African-Americans and quantitative cross-sectional surveys) study on factors associated with biospecimen knowledge and...

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Dash C, Wallington SF, Muthra S, et al. Disparities in knowledge and willingness to donate research biospecimens: a mixed-methods study in an underserved urban community. J Community Genet. 2014;5(4):329-36doi: 10.1007/s12687-014-0187-z.
Dash, C., Wallington, S. F., Muthra, S., Dodson, E., Mandelblatt, J., & Adams-Campbell, L. L. (2014). Disparities in knowledge and willingness to donate research biospecimens: a mixed-methods study in an underserved urban community. Journal of community genetics, 5(4), 329-36. https://doi.org/10.1007/s12687-014-0187-z
Dash, Chiranjeev, et al. "Disparities in knowledge and willingness to donate research biospecimens: a mixed-methods study in an underserved urban community." Journal of community genetics vol. 5,4 (2014): 329-36. doi: https://doi.org/10.1007/s12687-014-0187-z
Dash C, Wallington SF, Muthra S, Dodson E, Mandelblatt J, Adams-Campbell LL. Disparities in knowledge and willingness to donate research biospecimens: a mixed-methods study in an underserved urban community. J Community Genet. 2014 Oct;5(4):329-36. doi: 10.1007/s12687-014-0187-z. Epub 2014 Apr 26. PMID: 24771039; PMCID: PMC4159473.
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Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.

JAK-STAT

Timofeeva OA, Tarasova NI.
PMID: 24058784
JAKSTAT. 2012 Oct 01;1(4):274-84. doi: 10.4161/jkst.22313.

Most attempts to develop inhibitors of STAT transcription factors target either activating phosphorylation of tyrosine residue or SH2 domains. However, all six domains of STATs are highly conserved between the species and play important roles in the function of...

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Timofeeva OA, Tarasova NI. Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation. JAKSTAT. 2012;1(4):274-84doi: 10.4161/jkst.22313.
Timofeeva, O. A., & Tarasova, N. I. (2012). Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation. JAK-STAT, 1(4), 274-84. https://doi.org/10.4161/jkst.22313
Timofeeva, Olga A, and Tarasova, Nadya I. "Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation." JAK-STAT vol. 1,4 (2012): 274-84. doi: https://doi.org/10.4161/jkst.22313
Timofeeva OA, Tarasova NI. Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation. JAKSTAT. 2012 Oct 01;1(4):274-84. doi: 10.4161/jkst.22313. PMID: 24058784; PMCID: PMC3670285.
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Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Cancer genetics

Vietsch EE, Graham GT, McCutcheon JN, Javaid A, Giaccone G, Marshall JL, Wellstein A.
PMID: 30447903
Cancer Genet. 2018 Dec;228:131-142. doi: 10.1016/j.cancergen.2018.11.001. Epub 2018 Nov 09.

Cancer is a heterogeneous disease harboring diverse subclonal populations that can be discriminated by their DNA mutations. Environmental pressure selects subclones that ultimately drive disease progression and tumor relapse. Circulating cell-free DNA (ccfDNA) can be used to approximate the...

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Vietsch EE, Graham GT, McCutcheon JN, et al. Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer. Cancer Genet. 2018;228:131-142doi: 10.1016/j.cancergen.2018.11.001.
Vietsch, E. E., Graham, G. T., McCutcheon, J. N., Javaid, A., Giaccone, G., Marshall, J. L., & Wellstein, A. (2018). Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer. Cancer genetics, 228131-142. https://doi.org/10.1016/j.cancergen.2018.11.001
Vietsch, Eveline E, et al. "Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer." Cancer genetics vol. 228 (2018): 131-142. doi: https://doi.org/10.1016/j.cancergen.2018.11.001
Vietsch EE, Graham GT, McCutcheon JN, Javaid A, Giaccone G, Marshall JL, Wellstein A. Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer. Cancer Genet. 2018 Dec;228:131-142. doi: 10.1016/j.cancergen.2018.11.001. Epub 2018 Nov 09. PMID: 30447903.
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Introduction to the Special Issue on Clinical and Public Health Genomics: Opportunities for translational behavioral medicine research, practice, and policy.

Translational behavioral medicine

Graves KD, Hall MJ, Tercyak KP.
PMID: 29385593
Transl Behav Med. 2018 Jan 29;8(1):4-6. doi: 10.1093/tbm/ibx068.

No abstract available.

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Graves KD, Hall MJ, Tercyak KP. Introduction to the Special Issue on Clinical and Public Health Genomics: Opportunities for translational behavioral medicine research, practice, and policy. Transl Behav Med. 2018;8(1):4-6doi: 10.1093/tbm/ibx068.
Graves, K. D., Hall, M. J., & Tercyak, K. P. (2018). Introduction to the Special Issue on Clinical and Public Health Genomics: Opportunities for translational behavioral medicine research, practice, and policy. Translational behavioral medicine, 8(1), 4-6. https://doi.org/10.1093/tbm/ibx068
Graves, Kristi D, et al. "Introduction to the Special Issue on Clinical and Public Health Genomics: Opportunities for translational behavioral medicine research, practice, and policy." Translational behavioral medicine vol. 8,1 (2018): 4-6. doi: https://doi.org/10.1093/tbm/ibx068
Graves KD, Hall MJ, Tercyak KP. Introduction to the Special Issue on Clinical and Public Health Genomics: Opportunities for translational behavioral medicine research, practice, and policy. Transl Behav Med. 2018 Jan 29;8(1):4-6. doi: 10.1093/tbm/ibx068. PMID: 29385593; PMCID: PMC6065537.
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Showing 1 to 12 of 162 entries