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Showing 1 to 12 of 97 entries
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Micro RNAs in the development of non-alcoholic fatty liver disease.

World journal of hepatology

Gerhard GS, DiStefano JK.
PMID: 25729477
World J Hepatol. 2015 Feb 27;7(2):226-34. doi: 10.4254/wjh.v7.i2.226.

Nonalcoholic fatty liver disease or nonalcoholic fatty liver disease (NAFLD) refers to a group of disorders that arise from the accrual of fat in hepatocytes. Although various factors have been associated with the development of NAFLD, including genetic predisposition...

DASH (Dietary Approaches to Stop Hypertension) Diet and Risk of Subsequent Kidney Disease.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Rebholz CM, Crews DC, Grams ME, Steffen LM, Levey AS, Miller ER, Appel LJ, Coresh J.
PMID: 27519166
Am J Kidney Dis. 2016 Dec;68(6):853-861. doi: 10.1053/j.ajkd.2016.05.019. Epub 2016 Aug 09.

BACKGROUND: There are established guidelines for recommended dietary intake for hypertension treatment and cardiovascular disease prevention. Evidence is lacking for effective dietary patterns for kidney disease prevention.STUDY DESIGN: Prospective cohort study.SETTING & PARTICIPANTS: Atherosclerosis Risk in Communities (ARIC) Study...

Does IRISIN Have a BRITE Future as a Therapeutic Agent in Humans?.

Current obesity reports

Irving BA, Still CD, Argyropoulos G.
PMID: 24818073
Curr Obes Rep. 2014 Feb 02;3:235-41. doi: 10.1007/s13679-014-0091-1. eCollection 2014.

The epidemic of obesity has contributed to the rapid rise in comorbid conditions such as cardiovascular disease, type 2 diabetes, sleep apnea, and hypertension among others. Therefore, there is a critical need to develop therapeutic strategies to reduce the...

Dissecting gene-environment contributions to Type 2 diabetes.

Diabetes management (London, England)

Mitchell BD, Hanson RL.
PMID: 24966891
Diabetes Manag (Lond). 2012 Sep;2(5):375-378. doi: 10.2217/dmt.12.47.

No abstract available.

Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study.

Thrombosis journal

Cole JW, Brown DW, Giles WH, Stine OC, O'Connell JR, Mitchell BD, Sorkin JD, Wozniak MA, Stern BJ, Sparks MJ, Dobbins MT, Shoffner LT, Zappala NK, Reinhart LJ, Kittner SJ.
PMID: 18727828
Thromb J. 2008 Aug 26;6:11. doi: 10.1186/1477-9560-6-11.

BACKGROUND: Although cigarette smoking is a well-established risk factor for vascular disease, the genetic mechanisms that link cigarette smoking to an increased incidence of stroke are not well understood. Genetic variations within the genes of the inflammatory pathways are...

Clinical impact of recent genetic discoveries in osteoporosis.

The application of clinical genetics

Mitchell BD, Streeten EA.
PMID: 24133373
Appl Clin Genet. 2013 Oct 04;6:75-85. doi: 10.2147/TACG.S52047.

Osteoporotic fracture carries an enormous public health burden in terms of mortality and morbidity. Current approaches to identify individuals at high risk for fracture are based on assessment of bone mineral density and presence of other osteoporosis risk factors....

Oxyhemoglobin Saturation Overshoot Following Obstructive Breathing Events Mitigates Sleep Apnea-Induced Glucose Elevations.

Frontiers in endocrinology

Pham LV, Schwartz AR, Jun JC.
PMID: 30190705
Front Endocrinol (Lausanne). 2018 Aug 23;9:477. doi: 10.3389/fendo.2018.00477. eCollection 2018.

No abstract available.

A Genome-Wide Association Study of Idiopathic Dilated Cardiomyopathy in African Americans.

Journal of personalized medicine

Xu H, Dorn GW, Shetty A, Parihar A, Dave T, Robinson SW, Gottlieb SS, Donahue MP, Tomaselli GF, Kraus WE, Mitchell BD, Liggett SB.
PMID: 29495422
J Pers Med. 2018 Feb 26;8(1). doi: 10.3390/jpm8010011.

Idiopathic dilated cardiomyopathy (IDC) is the most common form of non-ischemic chronic heart failure. Despite the higher prevalence of IDC in African Americans, the genetics of IDC have been relatively understudied in this ethnic group. We performed a genome-wide...

Sex-specific effects of serum sulfate level and .

Molecular genetics and metabolism reports

Tise CG, Anforth LE, Zhou AE, Perry JA, McArdle PF, Streeten EA, Shuldiner AR, Yerges-Armstrong LM.
PMID: 28154797
Mol Genet Metab Rep. 2017 Jan 27;10:84-91. doi: 10.1016/j.ymgmr.2017.01.005. eCollection 2017 Mar.

CONTEXT: Sulfate is critical in the biotransformation of multiple compounds via sulfation. These compounds include neurotransmitters, proteoglycans, xenobiotics, and hormones such as dehydroepiandrosterone (DHEA). Sulfation reactions are thought to be rate-limited by endogenous sulfate concentrations. The gene, OBJECTIVE: To...

Prolonged, Controlled Daytime versus Delayed Eating Impacts Weight and Metabolism.

Current biology : CB

Allison KC, Hopkins CM, Ruggieri M, Spaeth AM, Ahima RS, Zhang Z, Taylor DM, Goel N.
PMID: 33259790
Curr Biol. 2021 Feb 08;31(3):650-657.e3. doi: 10.1016/j.cub.2020.10.092. Epub 2020 Nov 30.

A delayed eating schedule is associated with increased risk of obesity and metabolic dysfunction in humans.

COVID-19 Vaccination Associated with Reduced Post-Operative SARS-CoV-2 Infection and Morbidity.

Annals of surgery

Prasad NK, Lake R, Englum BR, Turner DJ, Siddiqui T, Mayorga-Carlin M, Sorkin JD, Lal BK.
PMID: 34417362
Ann Surg. 2021 Aug 19; doi: 10.1097/SLA.0000000000005176. Epub 2021 Aug 19.

OBJECTIVE: The purpose of this study was to determine the effect of COVID-19 vaccination on postoperative mortality, pulmonary and thrombotic complications, readmissions and hospital lengths of stay among patients undergoing surgery in the United States.BACKGROUND: While vaccination prevents COVID-19,...

Stressful life events and openness to experience: Relevance to depression.

Journal of affective disorders

Chiappelli J, Kvarta M, Bruce H, Chen S, Kochunov P, Hong LE.
PMID: 34517244
J Affect Disord. 2021 Dec 01;295:711-716. doi: 10.1016/j.jad.2021.08.112. Epub 2021 Sep 04.

BACKGROUND: Stressful life events are known as risk factors for depression, though there is considerable heterogeneity in how people respond to stress. Previous studies have found an association between experience of stressful life events and the personality trait of...

Showing 1 to 12 of 97 entries