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Showing 1 to 12 of 98 entries
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A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid.

Alzheimer's research & therapy

Yang T, O'Malley TT, Kanmert D, Jerecic J, Zieske LR, Zetterberg H, Hyman BT, Walsh DM, Selkoe DJ.
PMID: 25802556
Alzheimers Res Ther. 2015 Mar 22;7(1):14. doi: 10.1186/s13195-015-0100-y. eCollection 2015.

INTRODUCTION: Amyloid β-protein oligomers play a key role in Alzheimer's disease (AD), but well-validated assays that routinely detect them in cerebrospinal fluid (CSF) are just emerging. We sought to confirm and extend a recent study using the Singulex Erenna...

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Yang T, O'Malley TT, Kanmert D, et al. A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid. Alzheimers Res Ther. 2015;7(1):14doi: 10.1186/s13195-015-0100-y.
Yang, T., O'Malley, T. T., Kanmert, D., Jerecic, J., Zieske, L. R., Zetterberg, H., Hyman, B. T., Walsh, D. M., & Selkoe, D. J. (2015). A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid. Alzheimer's research & therapy, 7(1), 14. https://doi.org/10.1186/s13195-015-0100-y
Yang, Ting, et al. "A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid." Alzheimer's research & therapy vol. 7,1 (2015): 14. doi: https://doi.org/10.1186/s13195-015-0100-y
Yang T, O'Malley TT, Kanmert D, Jerecic J, Zieske LR, Zetterberg H, Hyman BT, Walsh DM, Selkoe DJ. A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid. Alzheimers Res Ther. 2015 Mar 22;7(1):14. doi: 10.1186/s13195-015-0100-y. eCollection 2015. PMID: 25802556; PMCID: PMC4369838.
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Optogenetic pacing in Drosophila melanogaster.

Science advances

Alex A, Li A, Tanzi RE, Zhou C.
PMID: 26601299
Sci Adv. 2015 Oct 09;1(9):e1500639. doi: 10.1126/sciadv.1500639. eCollection 2015 Oct.

Electrical stimulation is currently the gold standard for cardiac pacing. However, it is invasive and nonspecific for cardiac tissues. We recently developed a noninvasive cardiac pacing technique using optogenetic tools, which are widely used in neuroscience. Optogenetic pacing of...

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Alex A, Li A, Tanzi RE, et al. Optogenetic pacing in Drosophila melanogaster. Sci Adv. 2015;1(9):e1500639doi: 10.1126/sciadv.1500639.
Alex, A., Li, A., Tanzi, R. E., & Zhou, C. (2015). Optogenetic pacing in Drosophila melanogaster. Science advances, 1(9), e1500639. https://doi.org/10.1126/sciadv.1500639
Alex, Aneesh, et al. "Optogenetic pacing in Drosophila melanogaster." Science advances vol. 1,9 (2015): e1500639. doi: https://doi.org/10.1126/sciadv.1500639
Alex A, Li A, Tanzi RE, Zhou C. Optogenetic pacing in Drosophila melanogaster. Sci Adv. 2015 Oct 09;1(9):e1500639. doi: 10.1126/sciadv.1500639. eCollection 2015 Oct. PMID: 26601299; PMCID: PMC4646813.
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Optical coherence tomography visualizes neurons in human entorhinal cortex.

Neurophotonics

Magnain C, Augustinack JC, Konukoglu E, Frosch MP, Sakadžić S, Varjabedian A, Garcia N, Wedeen VJ, Boas DA, Fischl B.
PMID: 25741528
Neurophotonics. 2015 Feb 09;2(1):015004. doi: 10.1117/1.NPh.2.1.015004.

The cytoarchitecture of the human brain is of great interest in diverse fields: neuroanatomy, neurology, neuroscience, and neuropathology. Traditional histology is a method that has been historically used to assess cell and fiber content in the

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Magnain C, Augustinack JC, Konukoglu E, et al. Optical coherence tomography visualizes neurons in human entorhinal cortex. Neurophotonics. 2015;2(1):015004doi: 10.1117/1.NPh.2.1.015004.
Magnain, C., Augustinack, J. C., Konukoglu, E., Frosch, M. P., Sakadžić, S., Varjabedian, A., Garcia, N., Wedeen, V. J., Boas, D. A., & Fischl, B. (2015). Optical coherence tomography visualizes neurons in human entorhinal cortex. Neurophotonics, 2(1), 015004. https://doi.org/10.1117/1.NPh.2.1.015004
Magnain, Caroline, et al. "Optical coherence tomography visualizes neurons in human entorhinal cortex." Neurophotonics vol. 2,1 (2015): 015004. doi: https://doi.org/10.1117/1.NPh.2.1.015004
Magnain C, Augustinack JC, Konukoglu E, Frosch MP, Sakadžić S, Varjabedian A, Garcia N, Wedeen VJ, Boas DA, Fischl B. Optical coherence tomography visualizes neurons in human entorhinal cortex. Neurophotonics. 2015 Feb 09;2(1):015004. doi: 10.1117/1.NPh.2.1.015004. PMID: 25741528; PMCID: PMC4346095.
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Multiple neuropathologies and dementia in the aging brain: a key role for cerebrovascular disease?.

Alzheimer's & dementia (New York, N. Y.)

Charidimou A, Viswanathan A.
PMID: 28944284
Alzheimers Dement (N Y). 2016 Nov;2(4):281-282. doi: 10.1016/j.trci.2016.11.001. Epub 2016 Nov 29.

No abstract available.

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Charidimou A, Viswanathan A. Multiple neuropathologies and dementia in the aging brain: a key role for cerebrovascular disease?. Alzheimers Dement (N Y). 2016;2(4):281-282doi: 10.1016/j.trci.2016.11.001.
Charidimou, A., & Viswanathan, A. (2016). Multiple neuropathologies and dementia in the aging brain: a key role for cerebrovascular disease?. Alzheimer's & dementia (New York, N. Y.), 2(4), 281-282. https://doi.org/10.1016/j.trci.2016.11.001
Charidimou, Andreas, and Viswanathan, Anand. "Multiple neuropathologies and dementia in the aging brain: a key role for cerebrovascular disease?." Alzheimer's & dementia (New York, N. Y.) vol. 2,4 (2016): 281-282. doi: https://doi.org/10.1016/j.trci.2016.11.001
Charidimou A, Viswanathan A. Multiple neuropathologies and dementia in the aging brain: a key role for cerebrovascular disease?. Alzheimers Dement (N Y). 2016 Nov;2(4):281-282. doi: 10.1016/j.trci.2016.11.001. Epub 2016 Nov 29. PMID: 28944284; PMCID: PMC5603192.
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Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms.

Neurology and therapy

Keine D, Zelek M, Walker JQ, Sabbagh MN.
PMID: 30900186
Neurol Ther. 2019 Jun;8(1):79-94. doi: 10.1007/s40120-019-0131-6. Epub 2019 Mar 21.

INTRODUCTION: Polypharmacy is a growing problem in the United States. The use of multiple medications increases the likelihood that a patient will experience potential drug interactions and adverse drug reactions (ADRs). Those individuals with dementia or Alzheimer's disease (AD)...

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Keine D, Zelek M, Walker JQ, et al. Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms. Neurol Ther. 2019;8(1):79-94doi: 10.1007/s40120-019-0131-6.
Keine, D., Zelek, M., Walker, J. Q., & Sabbagh, M. N. (2019). Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms. Neurology and therapy, 8(1), 79-94. https://doi.org/10.1007/s40120-019-0131-6
Keine, Dorothy, et al. "Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms." Neurology and therapy vol. 8,1 (2019): 79-94. doi: https://doi.org/10.1007/s40120-019-0131-6
Keine D, Zelek M, Walker JQ, Sabbagh MN. Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms. Neurol Ther. 2019 Jun;8(1):79-94. doi: 10.1007/s40120-019-0131-6. Epub 2019 Mar 21. PMID: 30900186; PMCID: PMC6534631.
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Uniform resolution of compact identifiers for biomedical data.

Scientific data

Wimalaratne SM, Juty N, Kunze J, Janée G, McMurry JA, Beard N, Jimenez R, Grethe JS, Hermjakob H, Martone ME, Clark T.
PMID: 29737976
Sci Data. 2018 May 08;5:180029. doi: 10.1038/sdata.2018.29.

Most biomedical data repositories issue locally-unique accessions numbers, but do not provide globally unique, machine-resolvable, persistent identifiers for their datasets, as required by publishers wishing to implement data citation in accordance with widely accepted principles. Local accessions may however...

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Wimalaratne SM, Juty N, Kunze J, et al. Uniform resolution of compact identifiers for biomedical data. Sci Data. 2018;5:180029doi: 10.1038/sdata.2018.29.
Wimalaratne, S. M., Juty, N., Kunze, J., Janée, G., McMurry, J. A., Beard, N., Jimenez, R., Grethe, J. S., Hermjakob, H., Martone, M. E., & Clark, T. (2018). Uniform resolution of compact identifiers for biomedical data. Scientific data, 5180029. https://doi.org/10.1038/sdata.2018.29
Wimalaratne, Sarala M, et al. "Uniform resolution of compact identifiers for biomedical data." Scientific data vol. 5 (2018): 180029. doi: https://doi.org/10.1038/sdata.2018.29
Wimalaratne SM, Juty N, Kunze J, Janée G, McMurry JA, Beard N, Jimenez R, Grethe JS, Hermjakob H, Martone ME, Clark T. Uniform resolution of compact identifiers for biomedical data. Sci Data. 2018 May 08;5:180029. doi: 10.1038/sdata.2018.29. PMID: 29737976; PMCID: PMC5944906.
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Permutation Tests for General Dependent Truncation.

Computational statistics & data analysis

Chiou SH, Qian J, Mormino E, Betensky RA.
PMID: 30613119
Comput Stat Data Anal. 2018 Dec;128:308-324. doi: 10.1016/j.csda.2018.07.012. Epub 2018 Jul 29.

Truncated survival data arise when the event time is observed only if it falls within a subject-specific region, known as the truncation set. Left-truncated data arise when there is delayed entry into a study, such that subjects are included...

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Chiou SH, Qian J, Mormino E, et al. Permutation Tests for General Dependent Truncation. Comput Stat Data Anal. 2018;128:308-324doi: 10.1016/j.csda.2018.07.012.
Chiou, S. H., Qian, J., Mormino, E., Betensky, R. A. (2018). Permutation Tests for General Dependent Truncation. Computational statistics & data analysis, 128308-324. https://doi.org/10.1016/j.csda.2018.07.012
Chiou, Sy Han, et al. "Permutation Tests for General Dependent Truncation." Computational statistics & data analysis vol. 128 (2018): 308-324. doi: https://doi.org/10.1016/j.csda.2018.07.012
Chiou SH, Qian J, Mormino E, Betensky RA. Permutation Tests for General Dependent Truncation. Comput Stat Data Anal. 2018 Dec;128:308-324. doi: 10.1016/j.csda.2018.07.012. Epub 2018 Jul 29. PMID: 30613119; PMCID: PMC6317381.
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Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment.

Journal of central nervous system disease

Curcio N, Wilmoth K, LoBue C, Cullum CM.
PMID: 31040738
J Cent Nerv Syst Dis. 2019 Apr 22;11:1179573519843874. doi: 10.1177/1179573519843874. eCollection 2019.

BACKGROUND: Clinical diagnosis of cognitive disorders depends on accurate reporting of medical history, yet little is known about the reliability and the validity of such reports, particularly in older patients with and without cognitive impairment.METHODS: In 2 studies, we...

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Curcio N, Wilmoth K, LoBue C, et al. Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment. J Cent Nerv Syst Dis. 2019;11:1179573519843874doi: 10.1177/1179573519843874.
Curcio, N., Wilmoth, K., LoBue, C., & Cullum, C. M. (2019). Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment. Journal of central nervous system disease, 111179573519843874. https://doi.org/10.1177/1179573519843874
Curcio, Nicholas, et al. "Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment." Journal of central nervous system disease vol. 11 (2019): 1179573519843874. doi: https://doi.org/10.1177/1179573519843874
Curcio N, Wilmoth K, LoBue C, Cullum CM. Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment. J Cent Nerv Syst Dis. 2019 Apr 22;11:1179573519843874. doi: 10.1177/1179573519843874. eCollection 2019. PMID: 31040738; PMCID: PMC6477758.
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Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer's Coordinating Center Participants.

Journal of Alzheimer's disease reports

Wang G, Li W.
PMID: 33681711
J Alzheimers Dis Rep. 2021 Jan 11;5(1):1-6. doi: 10.3233/ADR-200275.

BACKGROUND: It is inconclusive on how sex affects the risk of developing mild cognitive impairment (MCI) or dementia.OBJECTIVE: To investigate how sex affects the risk of developing MCI or dementia.METHODS: A secondary data analysis was performed on data collected...

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Wang G, Li W. Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer's Coordinating Center Participants. J Alzheimers Dis Rep. 2021;5(1):1-6doi: 10.3233/ADR-200275.
Wang, G., & Li, W. (2021). Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer's Coordinating Center Participants. Journal of Alzheimer's disease reports, 5(1), 1-6. https://doi.org/10.3233/ADR-200275
Wang, Ge, and Li, Wei. "Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer's Coordinating Center Participants." Journal of Alzheimer's disease reports vol. 5,1 (2021): 1-6. doi: https://doi.org/10.3233/ADR-200275
Wang G, Li W. Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer's Coordinating Center Participants. J Alzheimers Dis Rep. 2021 Jan 11;5(1):1-6. doi: 10.3233/ADR-200275. PMID: 33681711; PMCID: PMC7902986.
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Plasma-borne indicators of inflammasome activity in Parkinson's disease patients.

NPJ Parkinson's disease

Anderson FL, von Herrmann KM, Andrew AS, Kuras YI, Young AL, Scherzer CR, Hickey WF, Lee SL, Havrda MC.
PMID: 33398042
NPJ Parkinsons Dis. 2021 Jan 04;7(1):2. doi: 10.1038/s41531-020-00147-6.

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms and loss of dopaminergic neurons of the substantia nigra. Inflammation and cell death are recognized aspects of PD suggesting that strategies to monitor and modify these...

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Anderson FL, von Herrmann KM, Andrew AS, et al. Plasma-borne indicators of inflammasome activity in Parkinson's disease patients. NPJ Parkinsons Dis. 2021;7(1):2doi: 10.1038/s41531-020-00147-6.
Anderson, F. L., von Herrmann, K. M., Andrew, A. S., Kuras, Y. I., Young, A. L., Scherzer, C. R., Hickey, W. F., Lee, S. L., & Havrda, M. C. (2021). Plasma-borne indicators of inflammasome activity in Parkinson's disease patients. NPJ Parkinson's disease, 7(1), 2. https://doi.org/10.1038/s41531-020-00147-6
Anderson, Faith L, et al. "Plasma-borne indicators of inflammasome activity in Parkinson's disease patients." NPJ Parkinson's disease vol. 7,1 (2021): 2. doi: https://doi.org/10.1038/s41531-020-00147-6
Anderson FL, von Herrmann KM, Andrew AS, Kuras YI, Young AL, Scherzer CR, Hickey WF, Lee SL, Havrda MC. Plasma-borne indicators of inflammasome activity in Parkinson's disease patients. NPJ Parkinsons Dis. 2021 Jan 04;7(1):2. doi: 10.1038/s41531-020-00147-6. PMID: 33398042; PMCID: PMC7782812.
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Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners.

International journal of geriatric psychiatry

Wilkins JM, Locascio JJ, Gunther JM, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OI.
PMID: 34498322
Int J Geriatr Psychiatry. 2021 Sep 08; doi: 10.1002/gps.5620. Epub 2021 Sep 08.

OBJECTIVES: Persons with progressive cognitive impairment (CI) increasingly rely on surrogate decision-makers for everyday activities. Yet, little is known about changes in everyday preferences over time or about concordance between persons with CI and their care partners regarding longitudinal...

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Wilkins JM, Locascio JJ, Gunther JM, et al. Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. Int J Geriatr Psychiatry. 2021;doi: 10.1002/gps.5620.
Wilkins, J. M., Locascio, J. J., Gunther, J. M., Gomez-Isla, T., Hyman, B. T., Blacker, D., Forester, B. P., & Okereke, O. I. (2021). Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. International journal of geriatric psychiatry, . https://doi.org/10.1002/gps.5620
Wilkins, James M, et al. "Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners." International journal of geriatric psychiatry vol. (2021). doi: https://doi.org/10.1002/gps.5620
Wilkins JM, Locascio JJ, Gunther JM, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OI. Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. Int J Geriatr Psychiatry. 2021 Sep 08; doi: 10.1002/gps.5620. Epub 2021 Sep 08. PMID: 34498322.
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Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies.

Brain communications

Sanderson JB, De S, Jiang H, Rovere M, Jin M, Zaccagnini L, Hays Watson A, De Boni L, Lagomarsino VN, Young-Pearse TL, Liu X, Pochapsky TC, Hyman BT, Dickson DW, Klenerman D, Selkoe DJ, Bartels T.
PMID: 32280944
Brain Commun. 2020;2(1):fcaa010. doi: 10.1093/braincomms/fcaa010. Epub 2020 Feb 11.

Since researchers identified α-synuclein as the principal component of Lewy bodies and Lewy neurites, studies have suggested that it plays a causative role in the pathogenesis of dementia with Lewy bodies and other 'synucleinopathies'. While α-synuclein dyshomeostasis likely contributes...

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Sanderson JB, De S, Jiang H, et al. Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain Commun. 2020;2(1):fcaa010doi: 10.1093/braincomms/fcaa010.
Sanderson, J. B., De, S., Jiang, H., Rovere, M., Jin, M., Zaccagnini, L., Hays Watson, A., De Boni, L., Lagomarsino, V. N., Young-Pearse, T. L., Liu, X., Pochapsky, T. C., Hyman, B. T., Dickson, D. W., Klenerman, D., Selkoe, D. J., & Bartels, T. (2020). Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain communications, 2(1), fcaa010. https://doi.org/10.1093/braincomms/fcaa010
Sanderson, John B, et al. "Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies." Brain communications vol. 2,1 (2020): fcaa010. doi: https://doi.org/10.1093/braincomms/fcaa010
Sanderson JB, De S, Jiang H, Rovere M, Jin M, Zaccagnini L, Hays Watson A, De Boni L, Lagomarsino VN, Young-Pearse TL, Liu X, Pochapsky TC, Hyman BT, Dickson DW, Klenerman D, Selkoe DJ, Bartels T. Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain Commun. 2020;2(1):fcaa010. doi: 10.1093/braincomms/fcaa010. Epub 2020 Feb 11. PMID: 32280944; PMCID: PMC7130446.
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Showing 1 to 12 of 98 entries