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The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects.

NPJ schizophrenia

Ellingrod VL, Grove TB, Burghardt KJ, Taylor SF, Dalack G.
PMID: 27336047
NPJ Schizophr. 2015 Nov 11;1:15046. doi: 10.1038/npjschz.2015.46. eCollection 2015.

BACKGROUND: Metabolic syndrome may be related to folate's pharmacogenetically regulated metabolism and atypical antipsychotic (AAP) exposure.AIMS: We examined folate supplementation on metabolic measures, endothelial functioning (Reactive Hyperemia Index (RHI)), and global methylation in AAP-treated schizophrenia subjects meeting NCEP-ATP-III-a metabolic...

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Ellingrod VL, Grove TB, Burghardt KJ, et al. The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. NPJ Schizophr. 2015;1:15046doi: 10.1038/npjschz.2015.46.
Ellingrod, V. L., Grove, T. B., Burghardt, K. J., Taylor, S. F., & Dalack, G. (2015). The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. NPJ schizophrenia, 115046. https://doi.org/10.1038/npjschz.2015.46
Ellingrod, Vicki L, et al. "The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects." NPJ schizophrenia vol. 1 (2015): 15046. doi: https://doi.org/10.1038/npjschz.2015.46
Ellingrod VL, Grove TB, Burghardt KJ, Taylor SF, Dalack G. The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. NPJ Schizophr. 2015 Nov 11;1:15046. doi: 10.1038/npjschz.2015.46. eCollection 2015. PMID: 27336047; PMCID: PMC4849464.
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Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves.

Annals of clinical and translational neurology

Hamid HS, Mervak CM, Münch AE, Robell NJ, Hayes JM, Porzio MT, Singleton JR, Smith AG, Feldman EL, Lentz SI.
PMID: 25493271
Ann Clin Transl Neurol. 2014 Oct;1(10):799-812. doi: 10.1002/acn3.119. Epub 2014 Oct 01.

OBJECTIVE: This study focused on altered mitochondrial dynamics as a potential mechanism for diabetic peripheral neuropathy (DPN). We employed both an in vitro sensory neuron model and an in situ analysis of human intraepidermal nerve fibers (IENFs) from cutaneous...

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Hamid HS, Mervak CM, Münch AE, et al. Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves. Ann Clin Transl Neurol. 2014;1(10):799-812doi: 10.1002/acn3.119.
Hamid, H. S., Mervak, C. M., Münch, A. E., Robell, N. J., Hayes, J. M., Porzio, M. T., Singleton, J. R., Smith, A. G., Feldman, E. L., & Lentz, S. I. (2014). Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves. Annals of clinical and translational neurology, 1(10), 799-812. https://doi.org/10.1002/acn3.119
Hamid, Hussein S, et al. "Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves." Annals of clinical and translational neurology vol. 1,10 (2014): 799-812. doi: https://doi.org/10.1002/acn3.119
Hamid HS, Mervak CM, Münch AE, Robell NJ, Hayes JM, Porzio MT, Singleton JR, Smith AG, Feldman EL, Lentz SI. Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves. Ann Clin Transl Neurol. 2014 Oct;1(10):799-812. doi: 10.1002/acn3.119. Epub 2014 Oct 01. PMID: 25493271; PMCID: PMC4241807.
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Improving eye care for veterans with diabetes: an example of using the QUERI steps to move from evidence to implementation: QUERI Series.

Implementation science : IS

Krein SL, Bernstein SJ, Fletcher CE, Makki F, Goldzweig CL, Watts B, Vijan S, Hayward RA.
PMID: 18353187
Implement Sci. 2008 Mar 19;3:18. doi: 10.1186/1748-5908-3-18.

BACKGROUND: Despite being a critical part of improving healthcare quality, little is known about how best to move important research findings into clinical practice. To address this issue, the Department of Veterans Affairs (VA) developed the Quality Enhancement Research...

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Krein SL, Bernstein SJ, Fletcher CE, et al. Improving eye care for veterans with diabetes: an example of using the QUERI steps to move from evidence to implementation: QUERI Series. Implement Sci. 2008;3:18doi: 10.1186/1748-5908-3-18.
Krein, S. L., Bernstein, S. J., Fletcher, C. E., Makki, F., Goldzweig, C. L., Watts, B., Vijan, S., & Hayward, R. A. (2008). Improving eye care for veterans with diabetes: an example of using the QUERI steps to move from evidence to implementation: QUERI Series. Implementation science : IS, 318. https://doi.org/10.1186/1748-5908-3-18
Krein, Sarah L, et al. "Improving eye care for veterans with diabetes: an example of using the QUERI steps to move from evidence to implementation: QUERI Series." Implementation science : IS vol. 3 (2008): 18. doi: https://doi.org/10.1186/1748-5908-3-18
Krein SL, Bernstein SJ, Fletcher CE, Makki F, Goldzweig CL, Watts B, Vijan S, Hayward RA. Improving eye care for veterans with diabetes: an example of using the QUERI steps to move from evidence to implementation: QUERI Series. Implement Sci. 2008 Mar 19;3:18. doi: 10.1186/1748-5908-3-18. PMID: 18353187; PMCID: PMC2277434.
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Fatty Acid desaturase gene polymorphisms and metabolic measures in schizophrenia and bipolar patients taking antipsychotics.

Cardiovascular psychiatry and neurology

Burghardt KJ, Gardner KN, Johnson JW, Ellingrod VL.
PMID: 24455201
Cardiovasc Psychiatry Neurol. 2013;2013:596945. doi: 10.1155/2013/596945. Epub 2013 Dec 21.

Atypical antipsychotics have become a common therapeutic option in both schizophrenia and bipolar disorder. However, these medications come with a high risk of metabolic side effects, particularly dyslipidemia and insulin resistance. Therefore, identification of patients who are at increased...

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Burghardt KJ, Gardner KN, Johnson JW, et al. Fatty Acid desaturase gene polymorphisms and metabolic measures in schizophrenia and bipolar patients taking antipsychotics. Cardiovasc Psychiatry Neurol. 2013;2013:596945doi: 10.1155/2013/596945.
Burghardt, K. J., Gardner, K. N., Johnson, J. W., & Ellingrod, V. L. (2013). Fatty Acid desaturase gene polymorphisms and metabolic measures in schizophrenia and bipolar patients taking antipsychotics. Cardiovascular psychiatry and neurology, 2013596945. https://doi.org/10.1155/2013/596945
Burghardt, Kyle J, et al. "Fatty Acid desaturase gene polymorphisms and metabolic measures in schizophrenia and bipolar patients taking antipsychotics." Cardiovascular psychiatry and neurology vol. 2013 (2013): 596945. doi: https://doi.org/10.1155/2013/596945
Burghardt KJ, Gardner KN, Johnson JW, Ellingrod VL. Fatty Acid desaturase gene polymorphisms and metabolic measures in schizophrenia and bipolar patients taking antipsychotics. Cardiovasc Psychiatry Neurol. 2013;2013:596945. doi: 10.1155/2013/596945. Epub 2013 Dec 21. PMID: 24455201; PMCID: PMC3880735.
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Use of Secondary Data to Estimate Instantaneous Model Parameters of Diabetic Heart Disease: Lemonade Method.

An international journal on information fusion

Ye W, Isaman DJ, Barhak J.
PMID: 22563307
Inf Fusion. 2012 Apr 01;13(2):137-145. doi: 10.1016/j.inffus.2010.08.003. Epub 2010 Sep 06.

With the increasing burden of chronic diseases on the health care system, Markov-type models are becoming popular to predict the long-term outcomes of early intervention and to guide disease management. However, statisticians have not been actively involved in the...

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Ye W, Isaman DJ, Barhak J. Use of Secondary Data to Estimate Instantaneous Model Parameters of Diabetic Heart Disease: Lemonade Method. Inf Fusion. 2010;13(2):137-145doi: 10.1016/j.inffus.2010.08.003.
Ye, W., Isaman, D. J., & Barhak, J. (2012). Use of Secondary Data to Estimate Instantaneous Model Parameters of Diabetic Heart Disease: Lemonade Method. An international journal on information fusion, 13(2), 137-145. https://doi.org/10.1016/j.inffus.2010.08.003
Ye, Wen, et al. "Use of Secondary Data to Estimate Instantaneous Model Parameters of Diabetic Heart Disease: Lemonade Method." An international journal on information fusion vol. 13,2 (2012): 137-145. doi: https://doi.org/10.1016/j.inffus.2010.08.003
Ye W, Isaman DJ, Barhak J. Use of Secondary Data to Estimate Instantaneous Model Parameters of Diabetic Heart Disease: Lemonade Method. Inf Fusion. 2012 Apr 01;13(2):137-145. doi: 10.1016/j.inffus.2010.08.003. Epub 2010 Sep 06. PMID: 22563307; PMCID: PMC3341173.
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The cost-effectiveness of diabetes prevention: results from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study.

Clinical diabetes and endocrinology

Herman WH.
PMID: 28702228
Clin Diabetes Endocrinol. 2015 Sep 02;1:9. doi: 10.1186/s40842-015-0009-1. eCollection 2015.

BACKGROUND: The Diabetes Prevention Program (DPP) was a randomized, controlled clinical trial. It demonstrated that among high-risk individuals with impaired glucose tolerance, diabetes incidence was reduced by 58 % with lifestyle intervention and 31 % with metformin compared to...

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Herman WH. The cost-effectiveness of diabetes prevention: results from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study. Clin Diabetes Endocrinol. 2015;1:9doi: 10.1186/s40842-015-0009-1.
Herman, W. H. (2015). The cost-effectiveness of diabetes prevention: results from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study. Clinical diabetes and endocrinology, 19. https://doi.org/10.1186/s40842-015-0009-1
Herman, William H. "The cost-effectiveness of diabetes prevention: results from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study." Clinical diabetes and endocrinology vol. 1 (2015): 9. doi: https://doi.org/10.1186/s40842-015-0009-1
Herman WH. The cost-effectiveness of diabetes prevention: results from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study. Clin Diabetes Endocrinol. 2015 Sep 02;1:9. doi: 10.1186/s40842-015-0009-1. eCollection 2015. PMID: 28702228; PMCID: PMC5471886.
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New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action.

Frontiers in medicine

Sheng L, Ye L, Zhang D, Cawthorn WP, Xu B.
PMID: 30238005
Front Med (Lausanne). 2018 Sep 06;5:244. doi: 10.3389/fmed.2018.00244. eCollection 2018.

Long non-coding RNAs (lncRNA) are emerging as new genetic/epigenetic regulators that can impact almost all physiological functions. Here, we focus on the long non-coding steroid receptor RNA activator (SRA), including new insights into its effects on gene expression, the...

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Sheng L, Ye L, Zhang D, et al. New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action. Front Med (Lausanne). 2018;5:244doi: 10.3389/fmed.2018.00244.
Sheng, L., Ye, L., Zhang, D., Cawthorn, W. P., & Xu, B. (2018). New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action. Frontiers in medicine, 5244. https://doi.org/10.3389/fmed.2018.00244
Sheng, Liang, et al. "New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action." Frontiers in medicine vol. 5 (2018): 244. doi: https://doi.org/10.3389/fmed.2018.00244
Sheng L, Ye L, Zhang D, Cawthorn WP, Xu B. New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action. Front Med (Lausanne). 2018 Sep 06;5:244. doi: 10.3389/fmed.2018.00244. eCollection 2018. PMID: 30238005; PMCID: PMC6135885.
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Magnetic resonance imaging of human neural stem cells in rodent and primate brain.

Stem cells translational medicine

McGinley LM, Willsey MS, Kashlan ON, Chen KS, Hayes JM, Bergin IL, Mason SN, Stebbins AW, Kwentus JF, Pacut C, Kollmer J, Sakowski SA, Bell CB, Chestek CA, Murphy GG, Patil PG, Feldman EL.
PMID: 32841522
Stem Cells Transl Med. 2021 Jan;10(1):83-97. doi: 10.1002/sctm.20-0126. Epub 2020 Aug 25.

Stem cell transplantation therapies are currently under investigation for central nervous system disorders. Although preclinical models show benefit, clinical translation is somewhat limited by the absence of reliable noninvasive methods to confirm targeting and monitor transplanted cells in vivo....

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McGinley LM, Willsey MS, Kashlan ON, et al. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2020;10(1):83-97doi: 10.1002/sctm.20-0126.
McGinley, L. M., Willsey, M. S., Kashlan, O. N., Chen, K. S., Hayes, J. M., Bergin, I. L., Mason, S. N., Stebbins, A. W., Kwentus, J. F., Pacut, C., Kollmer, J., Sakowski, S. A., Bell, C. B., Chestek, C. A., Murphy, G. G., Patil, P. G., & Feldman, E. L. (2021). Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem cells translational medicine, 10(1), 83-97. https://doi.org/10.1002/sctm.20-0126
McGinley, Lisa M, et al. "Magnetic resonance imaging of human neural stem cells in rodent and primate brain." Stem cells translational medicine vol. 10,1 (2021): 83-97. doi: https://doi.org/10.1002/sctm.20-0126
McGinley LM, Willsey MS, Kashlan ON, Chen KS, Hayes JM, Bergin IL, Mason SN, Stebbins AW, Kwentus JF, Pacut C, Kollmer J, Sakowski SA, Bell CB, Chestek CA, Murphy GG, Patil PG, Feldman EL. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2021 Jan;10(1):83-97. doi: 10.1002/sctm.20-0126. Epub 2020 Aug 25. PMID: 32841522; PMCID: PMC7780819.
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Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry.

Bio-protocol

Yu S, Münzberg H.
PMID: 29951570
Bio Protoc. 2018 Apr 20;8(8). doi: 10.21769/BioProtoc.2811.

The fundamental of neuroscience is to connect the firing of neurons to physiological and behavioral outcomes. Chemogenetics enables researchers to control the activity of a genetically defined population of neurons

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Yu S, Münzberg H. Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio Protoc. 2018;8(8)doi: 10.21769/BioProtoc.2811.
Yu, S., & Münzberg, H. (2018). Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio-protocol, 8(8), . https://doi.org/10.21769/BioProtoc.2811
Yu, Sangho, and Münzberg, Heike. "Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry." Bio-protocol vol. 8,8 (2018). doi: https://doi.org/10.21769/BioProtoc.2811
Yu S, Münzberg H. Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio Protoc. 2018 Apr 20;8(8). doi: 10.21769/BioProtoc.2811. PMID: 29951570; PMCID: PMC6018017.
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Magnetic resonance imaging of human neural stem cells in rodent and primate brain.

Stem cells translational medicine

McGinley LM, Willsey MS, Kashlan ON, Chen KS, Hayes JM, Bergin IL, Mason SN, Stebbins AW, Kwentus JF, Pacut C, Kollmer J, Sakowski SA, Bell CB, Chestek CA, Murphy GG, Patil PG, Feldman EL.
PMID: 32841522
Stem Cells Transl Med. 2021 Jan;10(1):83-97. doi: 10.1002/sctm.20-0126. Epub 2020 Aug 25.

Stem cell transplantation therapies are currently under investigation for central nervous system disorders. Although preclinical models show benefit, clinical translation is somewhat limited by the absence of reliable noninvasive methods to confirm targeting and monitor transplanted cells in vivo....

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McGinley LM, Willsey MS, Kashlan ON, et al. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2020;10(1):83-97doi: 10.1002/sctm.20-0126.
McGinley, L. M., Willsey, M. S., Kashlan, O. N., Chen, K. S., Hayes, J. M., Bergin, I. L., Mason, S. N., Stebbins, A. W., Kwentus, J. F., Pacut, C., Kollmer, J., Sakowski, S. A., Bell, C. B., Chestek, C. A., Murphy, G. G., Patil, P. G., & Feldman, E. L. (2021). Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem cells translational medicine, 10(1), 83-97. https://doi.org/10.1002/sctm.20-0126
McGinley, Lisa M, et al. "Magnetic resonance imaging of human neural stem cells in rodent and primate brain." Stem cells translational medicine vol. 10,1 (2021): 83-97. doi: https://doi.org/10.1002/sctm.20-0126
McGinley LM, Willsey MS, Kashlan ON, Chen KS, Hayes JM, Bergin IL, Mason SN, Stebbins AW, Kwentus JF, Pacut C, Kollmer J, Sakowski SA, Bell CB, Chestek CA, Murphy GG, Patil PG, Feldman EL. Magnetic resonance imaging of human neural stem cells in rodent and primate brain. Stem Cells Transl Med. 2021 Jan;10(1):83-97. doi: 10.1002/sctm.20-0126. Epub 2020 Aug 25. PMID: 32841522; PMCID: PMC7780819.
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Influence of a Community Health Worker Intervention on Mental Health Outcomes among Low-Income Latino and African American Adults with Type 2 Diabetes.

Race and social problems

Spencer MS, Hawkins J, Espitia NR, Sinco B, Jennings T, Lewis C, Palmisano G, Kieffer E.
PMID: 26448789
Race Soc Probl. 2013 Jun 01;5(2):137-146. doi: 10.1007/s12552-013-9098-6.

This study investigated the influence of a community health worker (CHW) diabetes lifestyle intervention on mental health outcomes. Our study was guided by the principles of community-based participatory research. Data were collected from 164 African American (

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Spencer MS, Hawkins J, Espitia NR, et al. Influence of a Community Health Worker Intervention on Mental Health Outcomes among Low-Income Latino and African American Adults with Type 2 Diabetes. Race Soc Probl. 2013;5(2):137-146doi: 10.1007/s12552-013-9098-6.
Spencer, M. S., Hawkins, J., Espitia, N. R., Sinco, B., Jennings, T., Lewis, C., Palmisano, G., & Kieffer, E. (2013). Influence of a Community Health Worker Intervention on Mental Health Outcomes among Low-Income Latino and African American Adults with Type 2 Diabetes. Race and social problems, 5(2), 137-146. https://doi.org/10.1007/s12552-013-9098-6
Spencer, Michael S, et al. "Influence of a Community Health Worker Intervention on Mental Health Outcomes among Low-Income Latino and African American Adults with Type 2 Diabetes." Race and social problems vol. 5,2 (2013): 137-146. doi: https://doi.org/10.1007/s12552-013-9098-6
Spencer MS, Hawkins J, Espitia NR, Sinco B, Jennings T, Lewis C, Palmisano G, Kieffer E. Influence of a Community Health Worker Intervention on Mental Health Outcomes among Low-Income Latino and African American Adults with Type 2 Diabetes. Race Soc Probl. 2013 Jun 01;5(2):137-146. doi: 10.1007/s12552-013-9098-6. PMID: 26448789; PMCID: PMC4593061.
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First Things First: Difficulty with Current Medications Is Associated With Patient Willingness to Add New Ones.

The patient

Zikmund-Fisher BJ, Hofer TP, Klamerus ML, Kerr EA.
PMID: 20634991
Patient. 2009 Dec 01;2(4):221-231. doi: 10.2165/11313850-000000000-00000.

BACKGROUND: Inadequate blood pressure (BP) control remains prevalent. One proposed explanation is "clinical inertia," often defined as the failure by providers to initiate or intensify medication therapy when otherwise appropriate. However, patients could contribute to clinical inertia by signaling...

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Zikmund-Fisher BJ, Hofer TP, Klamerus ML, et al. First Things First: Difficulty with Current Medications Is Associated With Patient Willingness to Add New Ones. Patient. 2009;2(4):221-231doi: 10.2165/11313850-000000000-00000.
Zikmund-Fisher, B. J., Hofer, T. P., Klamerus, M. L., & Kerr, E. A. (2009). First Things First: Difficulty with Current Medications Is Associated With Patient Willingness to Add New Ones. The patient, 2(4), 221-231. https://doi.org/10.2165/11313850-000000000-00000
Zikmund-Fisher, Brian J, et al. "First Things First: Difficulty with Current Medications Is Associated With Patient Willingness to Add New Ones." The patient vol. 2,4 (2009): 221-231. doi: https://doi.org/10.2165/11313850-000000000-00000
Zikmund-Fisher BJ, Hofer TP, Klamerus ML, Kerr EA. First Things First: Difficulty with Current Medications Is Associated With Patient Willingness to Add New Ones. Patient. 2009 Dec 01;2(4):221-231. doi: 10.2165/11313850-000000000-00000. PMID: 20634991; PMCID: PMC2902151.
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Showing 1 to 12 of 40 entries