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Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme.

Biomedicines

González-Casimiro CM, Merino B, Casanueva-Álvarez E, Postigo-Casado T, Cámara-Torres P, Fernández-Díaz CM, Leissring MA, Cózar-Castellano I, Perdomo G.
PMID: 33477364
Biomedicines. 2021 Jan 17;9(1). doi: 10.3390/biomedicines9010086.

Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed metalloprotease that degrades insulin and several other intermediate-size peptides. For many decades, IDE had been assumed to be involved primarily in hepatic insulin clearance, a key process that regulates...

Showing 1 to 1 of 1 entries