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Showing 1 to 12 of 73 entries
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Comparison between effects of pressure support and pressure-controlled ventilation on lung and diaphragmatic damage in experimental emphysema.

Intensive care medicine experimental

Padilha GA, Horta LF, Moraes L, Braga CL, Oliveira MV, Santos CL, Ramos IP, Morales MM, Capelozzi VL, Goldenberg RC, de Abreu MG, Pelosi P, Silva PL, Rocco PR.
PMID: 27761886
Intensive Care Med Exp. 2016 Dec;4(1):35. doi: 10.1186/s40635-016-0107-0. Epub 2016 Oct 19.

BACKGROUND: In patients with emphysema, invasive mechanical ventilation settings should be adjusted to minimize hyperinflation while reducing respiratory effort and providing adequate gas exchange. We evaluated the impact of pressure-controlled ventilation (PCV) and pressure support ventilation (PSV) on pulmonary...

Protein Crystallography at Ultra-Short Wavelengths: Feasibility Study of Anomalous-Dispersion Experiments at the Xenon K-edge.

Journal of synchrotron radiation

Schiltz M, Kvick A, Svensson OS, Shepard W, de La Fortelle E, Prangé T, Kahn R, Bricogne G, Fourme R.
PMID: 16699242
J Synchrotron Radiat. 1997 Sep 01;4:287-97. doi: 10.1107/S0909049597008571.

A protein crystallography experiment at the xenon K-edge (lambda = 0.358 A) has been successfully carried out at the materials science beamline (BL2/ID11) of the ESRF. The samples used in this methodological study were crystals of porcine pancreatic elastase,...

Structure of native pancreatic elastase from North Atlantic salmon at 1.61 A resolution.

Acta crystallographica. Section D, Biological crystallography

Berglund GI, Willassen NP, Hordvik A, Smalås AO.
PMID: 15299762
Acta Crystallogr D Biol Crystallogr. 1995 Nov 01;51:925-37. doi: 10.1107/S0907444995004835.

The crystal structure of native salmon pancreatic elastase (SPE) has been solved by molecular-replacement methods, and refined by conventional conjugate-gradient methods and simulated-annealing techniques. The final R value is 17.2% for 21 389 reflections between 8.0 and 1.61 A,...

Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia.

International journal of endocrinology

Pei G, Lv W, Li X, Zhang G, Zhang J.
PMID: 29138633
Int J Endocrinol. 2017;2017:3709306. doi: 10.1155/2017/3709306. Epub 2017 Aug 24.

OBJECTIVE: This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas-kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia.METHODS: A total of 19 patients with simultaneous...

Exocrine Dysfunction Correlates with Endocrinal Impairment of Pancreas in Type 2 Diabetes Mellitus.

Indian journal of endocrinology and metabolism

Prasanna Kumar HR, Gowdappa HB, Hosmani T, Urs T.
PMID: 29535950
Indian J Endocrinol Metab. 2018 Jan-Feb;22(1):121-125. doi: 10.4103/ijem.IJEM_139_17.

BACKGROUND: Diabetes mellitus (DM) is a chronic abnormal metabolic condition, which manifests elevated blood sugar level over a prolonged period. The pancreatic endocrine system generally gets affected during diabetes, but often abnormal exocrine functions are also manifested due to...

Bruising as the first sign of exocrine pancreatic insufficiency in infancy.

Medicine and pharmacy reports

Szabo CE, Man OI, Şerban RS, Kiss E, Lazăr CF.
PMID: 31086851
Med Pharm Rep. 2019 Apr;92(2):200-204. doi: 10.15386/mpr-1231. Epub 2019 Apr 25.

Exocrine pancreatic insufficiency is an important cause of chronic malnutrition, secondary to maldigestion-malabsorption, which can be caused in children especially by cystic fibrosis, but also by other much rarer diseases. The case of a 6 months and 3 weeks...

Development of a Model for Abdominal Aortic Aneurysms in Swine.

The Journal of surgical research

De Leo N, Melillo A, Zhang P, Badach J, Miller H, Lin A, Williamson J, Ghobrial G, Gaughan J, Krishnadoss V, Noshadi I, Brown SA, Carpenter JP.
PMID: 34289418
J Surg Res. 2021 Jul 18;268:79-86. doi: 10.1016/j.jss.2021.05.047. Epub 2021 Jul 18.

INTRODUCTION: Producing a reliable large-animal model of AAA has proven challenging. We sought to create a reproducible swine model of AAA using enzymatic degradation of the aortic wall.METHODS: Twelve male Yorkshire swine received periadventitial injections of type 1 collagenase...

Translating mouse models of abdominal aortic aneurysm to the translational needs of vascular surgery.

JVS-vascular science

Busch A, Bleichert S, Ibrahim N, Wortmann M, Eckstein HH, Brostjan C, Wagenhäuser MU, Goergen CJ, Maegdefessel L.
PMID: 34778850
JVS Vasc Sci. 2021 Mar 03;2:219-234. doi: 10.1016/j.jvssci.2021.01.002. eCollection 2021.

INTRODUCTION: Abdominal aortic aneurysm (AAA) is a condition that has considerable socioeconomic impact and an eventual rupture is associated with high mortality and morbidity. Despite decades of research, surgical repair remains the treatment of choice and no medical therapy...

Progression and Regression of Abdominal Aortic Aneurysms in Mice.

Current medical science

Ding YC, Zhang XJ, Zhang JX, Zhai ZY, Zhang MX, Jiang BH.
PMID: 34643880
Curr Med Sci. 2021 Oct;41(5):901-908. doi: 10.1007/s11596-021-2425-z. Epub 2021 Oct 13.

OBJECTIVE: Abdominal aortic aneurysm (AAA) is a significant medical problem with a high mortality rate. Nevertheless, the underlying mechanism for the progression and regression of AAA is unknown.METHODS: Experimental model of AAA was first created by porcine pancreatic elastase...

Evaluation of Circulating Endothelial Progenitor Cells in Abdominal Aortic Aneurysms after Endovascular Aneurysm Repair.

International journal of stem cells

Wu W, Zhang J, Shao L, Huang H, Meng Q, Shen Z, Teng X.
PMID: 34711694
Int J Stem Cells. 2021 Oct 31; doi: 10.15283/ijsc21027. Epub 2021 Oct 31.

BACKGROUND AND OBJECTIVES: Circulating endothelial progenitor cells (EPCs) participate in vascular repair and predict cardiovascular outcomes. The aim of this study was to investigate the correlation between EPCs and abdominal aortic aneurysms (AAAs).METHODS AND RESULTS: Patients (age 67±9.41 years)...

Establishing the blood reference interval of pancreatic elastase-1: A prospective study.

Journal of gastroenterology and hepatology

Chi SF, Lai CY, Dong WT, Wang JM, Wang YY, Yang SS, Lin JT, Lee TY.
PMID: 34498301
J Gastroenterol Hepatol. 2021 Sep 08; doi: 10.1111/jgh.15685. Epub 2021 Sep 08.

BACKGROUND AND AIM: Pancreatic elastase-1 (PE-1) has been investigated in pancreatic disorders. However, the reference interval (RI) of PE-1 in blood remains unconfirmed. We aimed to establish the blood RI of PE-1 in an adult population.METHODS: In this prospective...

Fluorescence Determination of Peptidase Activity Based on the Quenching of a Fluorophore-Labelled Peptide by Graphene Oxide.

The protein journal

Le DV.
PMID: 33856620
Protein J. 2021 Oct;40(5):682-688. doi: 10.1007/s10930-021-09985-6. Epub 2021 Apr 15.

In this study, a fluorescence detection strategy is reported for the peptidase activity assay, which is based on fluorescence resonance energy transfer (FRET) from a fluorophore-labelled peptide to graphene oxide (GO). By the hydrolysis of the peptide, the fluorophore-labelled...

Showing 1 to 12 of 73 entries