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Anticonvulsant and neuroprotective effects of Rosa damascena hydro-alcoholic extract on rat hippocampus.

Avicenna journal of phytomedicine

Homayoun M, Seghatoleslam M, Pourzaki M, Shafieian R, Hosseini M, Ebrahimzadeh Bideskan A.
PMID: 26101759
Avicenna J Phytomed. 2015 May-Jun;5(3):260-70.

OBJECTIVE: Previously, analgesic, hypnotic, and anticonvulsant effects have been suggested for Rosa damascena (R. damascena). In the present study, possible anti-seizure and neuro-protective effects of hydro-alcoholic extract of R. damascena has been investigated after inducing seizures in rats by...

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Homayoun M, Seghatoleslam M, Pourzaki M, et al. Anticonvulsant and neuroprotective effects of Rosa damascena hydro-alcoholic extract on rat hippocampus. Avicenna J Phytomed. 2015;5(3):260-70
Homayoun, M., Seghatoleslam, M., Pourzaki, M., Shafieian, R., Hosseini, M., & Ebrahimzadeh Bideskan, A. (2015). Anticonvulsant and neuroprotective effects of Rosa damascena hydro-alcoholic extract on rat hippocampus. Avicenna journal of phytomedicine, 5(3), 260-70.
Homayoun, Mansour, et al. "Anticonvulsant and neuroprotective effects of Rosa damascena hydro-alcoholic extract on rat hippocampus." Avicenna journal of phytomedicine vol. 5,3 (2015): 260-70.
Homayoun M, Seghatoleslam M, Pourzaki M, Shafieian R, Hosseini M, Ebrahimzadeh Bideskan A. Anticonvulsant and neuroprotective effects of Rosa damascena hydro-alcoholic extract on rat hippocampus. Avicenna J Phytomed. 2015 May-Jun;5(3):260-70. PMID: 26101759; PMCID: PMC4469956.
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Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice.

EXCLI journal

Bhat JU, Nizami Q, Asiaf A, Parray SA, Ahmad ST, Aslam M, Khanam R, Mujeeb M, Umar S, Siddiqi A.
PMID: 27298604
EXCLI J. 2012 Jan 20;11:1-6. eCollection 2012.

The aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The...

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Bhat JU, Nizami Q, Asiaf A, et al. Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice. EXCLI J. 2012;11:1-6
Bhat, J. U., Nizami, Q., Asiaf, A., Parray, S. A., Ahmad, S. T., Aslam, M., Khanam, R., Mujeeb, M., Umar, S., & Siddiqi, A. (2012). Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice. EXCLI journal, 111-6.
Bhat, Jalal Uddin, et al. "Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice." EXCLI journal vol. 11 (2012): 1-6.
Bhat JU, Nizami Q, Asiaf A, Parray SA, Ahmad ST, Aslam M, Khanam R, Mujeeb M, Umar S, Siddiqi A. Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice. EXCLI J. 2012 Jan 20;11:1-6. eCollection 2012. PMID: 27298604; PMCID: PMC4897659.
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Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling-Induced Cognitive Impairment and Depressive-Like Behavior.

Frontiers in behavioral neuroscience

Zhu X, Dong J, Han B, Huang R, Zhang A, Xia Z, Chang H, Chao J, Yao H.
PMID: 29093670
Front Behav Neurosci. 2017 Oct 18;11:203. doi: 10.3389/fnbeh.2017.00203. eCollection 2017.

Epilepsy is a chronic neurological disease which is usually associated with psychiatric comorbidities. Depsression and cognition impairment are considered to be the most common psychiatric comorbidities in epilepsy patients. However, the specific contribution of epilepsy made to these psychiatric...

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Zhu X, Dong J, Han B, et al. Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling-Induced Cognitive Impairment and Depressive-Like Behavior. Front Behav Neurosci. 2017;11:203doi: 10.3389/fnbeh.2017.00203.
Zhu, X., Dong, J., Han, B., Huang, R., Zhang, A., Xia, Z., Chang, H., Chao, J., & Yao, H. (2017). Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling-Induced Cognitive Impairment and Depressive-Like Behavior. Frontiers in behavioral neuroscience, 11203. https://doi.org/10.3389/fnbeh.2017.00203
Zhu, Xinjian, et al. "Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling-Induced Cognitive Impairment and Depressive-Like Behavior." Frontiers in behavioral neuroscience vol. 11 (2017): 203. doi: https://doi.org/10.3389/fnbeh.2017.00203
Zhu X, Dong J, Han B, Huang R, Zhang A, Xia Z, Chang H, Chao J, Yao H. Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling-Induced Cognitive Impairment and Depressive-Like Behavior. Front Behav Neurosci. 2017 Oct 18;11:203. doi: 10.3389/fnbeh.2017.00203. eCollection 2017. PMID: 29093670; PMCID: PMC5651248.
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GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus.

Advanced pharmaceutical bulletin

Ataie Z, Babri S, Ghahramanian Golzar M, Ebrahimi H, Mirzaie F, Mohaddes G.
PMID: 24312860
Adv Pharm Bull. 2013;3(2):353-8. doi: 10.5681/apb.2013.057. Epub 2013 Aug 20.

PURPOSE: Ghrelin has been shown to have antiepileptic function. However, the underlying mechanisms by which, ghrelin exerts its antiepileptic effects are still unclear. In the present study; we investigated antiepileptic mechanism of ghrelin through GABAB receptors using CGP35348 (selective...

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Ataie Z, Babri S, Ghahramanian Golzar M, et al. GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus. Adv Pharm Bull. 2013;3(2):353-8doi: 10.5681/apb.2013.057.
Ataie, Z., Babri, S., Ghahramanian Golzar, M., Ebrahimi, H., Mirzaie, F., & Mohaddes, G. (2013). GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus. Advanced pharmaceutical bulletin, 3(2), 353-8. https://doi.org/10.5681/apb.2013.057
Ataie, Zohreh, et al. "GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus." Advanced pharmaceutical bulletin vol. 3,2 (2013): 353-8. doi: https://doi.org/10.5681/apb.2013.057
Ataie Z, Babri S, Ghahramanian Golzar M, Ebrahimi H, Mirzaie F, Mohaddes G. GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus. Adv Pharm Bull. 2013;3(2):353-8. doi: 10.5681/apb.2013.057. Epub 2013 Aug 20. PMID: 24312860; PMCID: PMC3848211.
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Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy.

International journal of clinical and experimental medicine

Sefil F, Arık AE, Acar MD, Bostancı MÖ, Bagirici F, Kozan R.
PMID: 26379841
Int J Clin Exp Med. 2015 Jul 15;8(7):10508-14. eCollection 2015.

Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the combination valproic acid with carbenoxolone...

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Sefil F, Arık AE, Acar MD, et al. Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy. Int J Clin Exp Med. 2015;8(7):10508-14
Sefil, F., Arık, A. E., Acar, M. D., Bostancı, M. �. �., Bagirici, F., & Kozan, R. (2015). Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy. International journal of clinical and experimental medicine, 8(7), 10508-14.
Sefil, Fatih, et al. "Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy." International journal of clinical and experimental medicine vol. 8,7 (2015): 10508-14.
Sefil F, Arık AE, Acar MD, Bostancı MÖ, Bagirici F, Kozan R. Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy. Int J Clin Exp Med. 2015 Jul 15;8(7):10508-14. eCollection 2015. PMID: 26379841; PMCID: PMC4565224.
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Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals.

Ancient science of life

Durg S, Veerapur VP, Thippeswamy BS, Ahamed SM.
PMID: 26865744
Anc Sci Life. 2015 Oct-Dec;35(2):110-7. doi: 10.4103/0257-7941.171675.

BACKGROUND: Śilājatu (Shilajit; SJ) is claimed in traditional Indian medical practice to be useful in the treatment of nervous disorders, epilepsy and as antistress.AIM: To investigate whether SJ possesses antiepileptic and antipsychotic activities in rodents.MATERIALS AND METHODS: Isonicotinyl hydrazine...

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Durg S, Veerapur VP, Thippeswamy BS, et al. Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals. Anc Sci Life. 2015;35(2):110-7doi: 10.4103/0257-7941.171675.
Durg, S., Veerapur, V. P., Thippeswamy, B. S., & Ahamed, S. M. (2015). Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals. Ancient science of life, 35(2), 110-7. https://doi.org/10.4103/0257-7941.171675
Durg, Sharanbasappa, et al. "Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals." Ancient science of life vol. 35,2 (2015): 110-7. doi: https://doi.org/10.4103/0257-7941.171675
Durg S, Veerapur VP, Thippeswamy BS, Ahamed SM. Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals. Anc Sci Life. 2015 Oct-Dec;35(2):110-7. doi: 10.4103/0257-7941.171675. PMID: 26865744; PMCID: PMC4728862.
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The Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats.

Iranian journal of pharmaceutical research : IJPR

Vafaee F, Hosseini M, Hassanzadeh Z, Edalatmanesh MA, Sadeghnia HR, Seghatoleslam M, Mousavi SM, Amani A, Shafei MN.
PMID: 25901163
Iran J Pharm Res. 2015;14(2):547-57.

Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro - alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (PTZ) - induced repeated seizures. There were 4 experimental groups...

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Vafaee F, Hosseini M, Hassanzadeh Z, et al. The Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats. Iran J Pharm Res. 2015;14(2):547-57
Vafaee, F., Hosseini, M., Hassanzadeh, Z., Edalatmanesh, M. A., Sadeghnia, H. R., Seghatoleslam, M., Mousavi, S. M., Amani, A., & Shafei, M. N. (2015). The Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats. Iranian journal of pharmaceutical research : IJPR, 14(2), 547-57.
Vafaee, Farzaneh, et al. "The Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats." Iranian journal of pharmaceutical research : IJPR vol. 14,2 (2015): 547-57.
Vafaee F, Hosseini M, Hassanzadeh Z, Edalatmanesh MA, Sadeghnia HR, Seghatoleslam M, Mousavi SM, Amani A, Shafei MN. The Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats. Iran J Pharm Res. 2015;14(2):547-57. PMID: 25901163; PMCID: PMC4403072.
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GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn.

Evidence-based complementary and alternative medicine : eCAM

Khan I, Karim N, Ahmad W, Abdelhalim A, Chebib M.
PMID: 27143980
Evid Based Complement Alternat Med. 2016;2016:1215393. doi: 10.1155/2016/1215393. Epub 2016 Apr 07.

Artemisia indica, also known as "Mugwort," has been widely used in traditional medicines. However, few studies have investigated the effects of nonvolatile components of Artemisia indica on central nervous system's function. Fractionation of Artemisia indica led to the isolation...

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Khan I, Karim N, Ahmad W, et al. GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn. Evid Based Complement Alternat Med. 2016;2016:1215393doi: 10.1155/2016/1215393.
Khan, I., Karim, N., Ahmad, W., Abdelhalim, A., & Chebib, M. (2016). GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn. Evidence-based complementary and alternative medicine : eCAM, 20161215393. https://doi.org/10.1155/2016/1215393
Khan, Imran, et al. "GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn." Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 1215393. doi: https://doi.org/10.1155/2016/1215393
Khan I, Karim N, Ahmad W, Abdelhalim A, Chebib M. GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn. Evid Based Complement Alternat Med. 2016;2016:1215393. doi: 10.1155/2016/1215393. Epub 2016 Apr 07. PMID: 27143980; PMCID: PMC4838807.
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Discriminative stimulus effects of the novel anxiolytic buspirone.

Behavioural pharmacology

Ator NA.
PMID: 11224042
Behav Pharmacol. 1991 Feb;2(1):3-14.

Separate groups of Long-Evans rats were trained to discriminate either 0.56 or 1.0mg/kg buspirone i.p. in a two-lever, drug vs no-drug discrimination procedure. Training took twice as long for the lower versus the higher training-dose group. Generalization tests were...

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Ator NA. Discriminative stimulus effects of the novel anxiolytic buspirone. Behav Pharmacol. 1991;2(1):3-14
Ator, N. A. (1991). Discriminative stimulus effects of the novel anxiolytic buspirone. Behavioural pharmacology, 2(1), 3-14.
Ator, N.A.. "Discriminative stimulus effects of the novel anxiolytic buspirone." Behavioural pharmacology vol. 2,1 (1991): 3-14.
Ator NA. Discriminative stimulus effects of the novel anxiolytic buspirone. Behav Pharmacol. 1991 Feb;2(1):3-14. PMID: 11224042.
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Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents.

International journal of Ayurveda research

Galani VJ, Patel BG.
PMID: 20814521
Int J Ayurveda Res. 2010 Apr;1(2):87-92. doi: 10.4103/0974-7788.64412.

To investigate the effects of a hydroalcoholic extract of the Sphaeranthus indicus (SIE) against experimentally induced anxiety, depression and convulsions in rodents. The SIE (100, 200, 500 mg/kg, p.o.) was used in elevated plus maze, open field, forced swimming,...

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Galani VJ, Patel BG. Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents. Int J Ayurveda Res. 2010;1(2):87-92doi: 10.4103/0974-7788.64412.
Galani, V. J., & Patel, B. G. (2010). Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents. International journal of Ayurveda research, 1(2), 87-92. https://doi.org/10.4103/0974-7788.64412
Galani, Varsha J, and Patel, Bharatkumar G. "Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents." International journal of Ayurveda research vol. 1,2 (2010): 87-92. doi: https://doi.org/10.4103/0974-7788.64412
Galani VJ, Patel BG. Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents. Int J Ayurveda Res. 2010 Apr;1(2):87-92. doi: 10.4103/0974-7788.64412. PMID: 20814521; PMCID: PMC2924989.
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Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors.

International journal of health sciences

Raza M, Alghasham AA, Alorainy MS, El-Hadiyah TM.
PMID: 21475467
Int J Health Sci (Qassim). 2008 Jan;2(1):15-25.

This study investigated antiepileptic effects of the main constituents of Nigella sativa (NS) seed (i.e. aqueous extract (AE), fixed oil (FO), volatile oil (VO)) and the main components of its VO (i.e. thymoquinone, α-pinene and p-cymene) using pentylenetetrazole (PTZ)...

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Raza M, Alghasham AA, Alorainy MS, et al. Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors. Int J Health Sci (Qassim). 2008;2(1):15-25
Raza, M., Alghasham, A. A., Alorainy, M. S., & El-Hadiyah, T. M. (2008). Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors. International journal of health sciences, 2(1), 15-25.
Raza, Muhammad, et al. "Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors." International journal of health sciences vol. 2,1 (2008): 15-25.
Raza M, Alghasham AA, Alorainy MS, El-Hadiyah TM. Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors. Int J Health Sci (Qassim). 2008 Jan;2(1):15-25. PMID: 21475467; PMCID: PMC3068708.
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Synthesis and anticonvulsant activity of some 4-nitro-N-phenylbenzamides.

European journal of medicinal chemistry

Bailleux V, Vallée L, Nuyts J, Hamoir G, Poupaert J, Stables J, Vamecq J.
PMID: 22625428
Eur J Med Chem. 1995;30(5):439-44. doi: 10.1016/0223-5234(96)88254-7.

A short series of 4-nitro-N-phenylbenzamides was synthesized and evaluated for anticonvulsant properties and neurotoxicity. In mice dosed intraperitoneally, three of the four 4-nitro-N-phenylbenzamides were efficient in the maximal electroshock-induced seizure (MES) test, especially N-(2,6-dimethylphenyl)-4-nitrobenzamide (ED(50) value in the MES...

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Bailleux V, Vallée L, Nuyts J, et al. Synthesis and anticonvulsant activity of some 4-nitro-N-phenylbenzamides. Eur J Med Chem. 1995;30(5):439-44doi: 10.1016/0223-5234(96)88254-7.
Bailleux, V., Vallée, L., Nuyts, J., Hamoir, G., Poupaert, J., Stables, J., & Vamecq, J. (1995). Synthesis and anticonvulsant activity of some 4-nitro-N-phenylbenzamides. European journal of medicinal chemistry, 30(5), 439-44. https://doi.org/10.1016/0223-5234(96)88254-7
Bailleux, V, et al. "Synthesis and anticonvulsant activity of some 4-nitro-N-phenylbenzamides." European journal of medicinal chemistry vol. 30,5 (1995): 439-44. doi: https://doi.org/10.1016/0223-5234(96)88254-7
Bailleux V, Vallée L, Nuyts J, Hamoir G, Poupaert J, Stables J, Vamecq J. Synthesis and anticonvulsant activity of some 4-nitro-N-phenylbenzamides. Eur J Med Chem. 1995;30(5):439-44. doi: 10.1016/0223-5234(96)88254-7. PMID: 22625428.
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Showing 1 to 12 of 293 entries